• Korean Journal of Psychosomatic Medicine
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• v.31 no.1
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• pp.19-24
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• 2023

Objectives : Biofeedback is a useful non-pharmacological treatment for panic disorder (PD), but no studies have identified physiological markers related to the treatment response. This study investigated predictors of the treatment response for biofeedback in patients with PD. Methods : A retrospective study based on the electronic medical records of 372 adult patients with PD was performed. Patients received biofeedback treatment at least once, and physiological markers including heart rate, heart rate variability, respiratory rate, skin conductance, skin temperature, and electromyography were collected before the treatment began. The patients were classified as responders or non-responders based on the change in Clinical Global Impression-Severity (CGI-S) score. Results : The response rate to biofeedback treatment was 30.4%. Multivariable logistic regression analysis revealed that a higher CGI-S score at baseline and fewer benzodiazepine prescriptions were associated with a better response to biofeedback treatment. According to subgroup analyses, the baseline CGI-S score, dose of benzodiazepines, and skin conductance are candidate predictors of the response to biofeedback treatment in men, while only baseline disease severity was associated with the treatment response in women. Conclusions : The present results suggest that skin conductance may be target marker and predictor for biofeedback in male patients with PD.

• Journal of Oriental Neuropsychiatry
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• v.24 no.3
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• pp.251-256
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• 2013

Objectives : Qi gong is generally considered to be safe in most people when learned from a qualified instructor. But abnormal psychosomatic responses or mental disorder may be induced when Qigong is practiced inappropriately, excessively, or when practiced unguided in predisposed individuals. Here we reported a case of Qigong-induced Mental Disorder (QIMD). A woman who had not had a psychiatric disease, by chance started Qigong practice, and felt raising- Qisymptoms, including headache. Methods : We identified the unique characteristics of QIMD and discusses differences with other diseases such as somatoform disorder and schizophrenia. Results : To conclude, QIMD does not come under current somatoform disorder subtypes and schizophrenia. Conclusions : It has distinct characters that occurring after Qigong practice, symptoms of upper body, feeling that something to rise up.

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.2
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• pp.111-119
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• 2001

Tic disorder which is purposeless, repeated, unexpected, involuntary behavior and voice can be divided into motor, vocal tic. Tic disorder belongs to pediatic psychosomatic disease. In four clinical cases, patients between the age of 6 to 15 consisted of three males and one females. They all are the eldest or only son and have the parental behavioral, home background and studing problem. The patients appealed to eye blinking in tic early stage and belong to chronic motor or vocal tic disorder or transient tic disorder without tourette's disorder. When estimated by an appraisal standard of Yale Global Tic Severity Scale(YGTSS). Four patients administered Bosimgeunatang known to invigorating the heart, relieving mental stress improved.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.1
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• pp.37-48
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• 2001

Objectives : The purpose of this study was to evaluate the difference of psychometric analysis among patients with Post-traumatic organic mental disorder according to the lesion of MRI finding of traumatic brain injury. Methods : We divided 35 patients into 4 groups according to the lesion of MRI finding of brain injury. We evaluated the difference of the subscales of MMPI and K-WAIS among 4 groups with Post-traumatic organic mental disorder by ANOVA. Results : We found no significant difference of all subscales of MMPI and K -WAIS among 4 groups by ANOVA. Compared Rt hemispheric injury group with Lt hemispheric injury group by independent t-test, the depression scale in MMPI scored significantly higher in Lt hemispheric injury group, and the block design in K-WAIS scored significantly lower in Rt hemispheric injury group. Conclusion : This study suggests that Lt hemispheric injury be significantly related to depression, and Rt hemispheric injury be significantly related to visuospatial ability.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.2
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• pp.103-121
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• 2004

Conversion disorder and factitious disorder should be ruled out before making diagnosis of malingering. For this work, inspection of patient's behavior along with complete neurological examinations, psychological tests, and meticulous psychiatric interview are necessary. Facial expression test, thermography, dynamometry were failed differentiating conversion disorders to the malingered pain and motor symptoms, however, controlled diagnostic block showed positive result partly in patients with regional or cervical pain syndrome. Chronic pain patients who are related to the process of litigation encounter stressful life situations which lead them into various neurobehavioral and psychosocial complications. Most of suspected malingered patients would not revealed pure form rather mixed with factitious and/or conversion features. At the time of increasing number of chronic patients associated with traffic accidents or industrial injuries who are involved in litigation, psychiatrist are needed sharp eyes and tenacity for evaluating malingering or medically unexplained symptoms.

• Korean Journal of Psychosomatic Medicine
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• v.20 no.2
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• pp.135-138
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• 2012

The pathophysiology of functional gastrointestinal disorder(FGID) is not completely understood, but the importance of the 'Brain-Gut Axis(BGA)' model in FGID is being increasingly recognized. The BGA model is a bidirectional, hard-wired and homeostatic relationship between the central nervous system(CNS) and the enteric nervous system(ENS) via neural, neurohormonal and neuroimmunological pathways. In addition, the BGA model would provide a rationale for the use of psychotropics on FGID. The authors experienced two cases in which duloxetine, a serotonin-norepinephrine reuptake inhibitor, was effective in relieving FGID symptoms as well as psychiatric symptoms such as depression and hypochondriacal anxiety. Therefore we discuss the vignettes from the perspective of BGA theory. Duloxetine showed efficacy in these two patients by reducing visceral hypersensivity (bottom-up regulation) and by relieving depression and anxiety(top-down regulation).

• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.134-141
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• 1999

Objects : Cancer patients receiving radiotherapy have many psychological problems. Those problems depend on clinical factors of cancer and the characteristics of patients. This study was designed to estimate the morbidity of psychiatric disorder and to investigate the relationship between psychiatric disorders and clinical variables. Methods : The subjects were 47 patients who had been treated by radiotherapy. Psychiatric disorder was diagnosed according to DSM-IV. The authors assessed the relation between psychiatric disorder and demographic features, clinical features of cancer such as site, duration, frequency of recurrence of cancer, and patients' awareness of disease and expectation of outcome of radiotherapy. Results : 21 patients(44.7%) had a psychiatric disorder. The most common psychiatric disorder were adjustment disorder(66.7%), and the next major depressive disorder(23.8%). There was a significant positive relationship between psychiatric disorder and recurrence of cancer, patients' expectation of poor outcome after radiotherapy. Psychiatric morbidity was significantly low in those who had no evidence of recurrence and who considered radiation treatment as curative. However, site and duration of cancer, patients' awareness about serious illness were not related with psychiatric disorder. Conclusion : Psychiatric disorders are common among cancer patients on radiotherapy. Further clinical attention and effective treatment of psychiatric complication in cancer patients are needed not only for reducing symptoms but for better adjustment.

• Journal of Oriental Neuropsychiatry
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• v.13 no.2
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• pp.11-19
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• 2002

Objectives : This study aimed investigation of mutual relation to a psychosomatic disorder and Sasang Constitutinal Medicine. Results : 1. A view of the body and mind, Sasang Constitutinal Medicine is similar to Mind-Body Medicine that a thought of the mind is the central idea. But a viewpoint of the mind to Sasang Constitutinal Medicine is based on Confucianism idea 2. The Nature and Emotion(性情)-a symbol of Happiness, Anger, Sorrow joy(喜怒哀樂) show a characteristic of man relate to an attack of a disease also take a disease itself. But Mind-Body Medicine recognize an attack of a disease caused only by the mind. 3. Sasang Constitutinal Medicine emphasize the care of health by respective The Nature and Emotion(性情) to the treatment and prevention of disease and drug therapy is an assistant. This is similar to an important meaning at psycho therapy-suggestive therapy, autogenic training, relaxation training etc in Mind-Body Medicine. Conclusions : Therefore, Sasang Constitutinal Medicine's clinical use in aspect of psychiatry, must to study human nature regard to korean traditional thought-Confucianism idea

• Korean Journal of Psychosomatic Medicine
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• v.6 no.1
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• pp.79-84
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• 1998

Authors report a case of poststroke bipolar disorder that occurs much less frequently than poststroke depression(PSD). A MRI study performed to identify the etiology of a secondary manic episode in a patient with preceded PSD after left basal ganglia infarction revealed newly developed right basal ganglia infarction associated with poststroke bipolar disorder. It is interesting to note that (1) the temporal relationship was found between the occurrence of PSD after left hemisphere stroke and the occurrence of poststroke bipolar disorder following right hemisphere stroke, and that (2) the occurrence of PSD and the occurrence of poststroke bipolar disorder are associated with lesion location respectively. It has been reported that bipolar disorders were associated with subcortical lesions of the right hemisphere, whereas right-cortical lesions led to unipolar mania and that risk factors for mania included a family history of psychiatric disorders and mild subcortical atrophy. In this case, MR image shows subcortical lesions of the right hemisphere and mild subcortical atrophy. The investigation of the relationships among stroke lesion locations and potstroke mood disorders and risk factors for poststroke bipolar disorder may contribute to understanding the neurobiology of primary mood disorder. A clinical implication is that the risk of secondary bipolar disorder after cerebral infarction should be highlighted.

• Korean Journal of Psychosomatic Medicine
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• v.23 no.2
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• pp.107-113
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• 2015

Objectives : The aim of this study was to investigate the factors including possibility of bipolar disorder that are related to intensity of suicidal idea. Methods : The study subjects consisted of 50 patients who did suicidal attempt and treated at the Inje University Haeundae Paik Hospital Emergency Room. All participants underwent psychiatric interview and underwent Columbia Suicide Severity Rating Scale(C-SSRS), Beck Depression Inventory(BDI), Korean Version of Mood Disorder Questionnaire(MDQ) and Bipolar Spectrum Diagnostic Scale(BSDS) to evaluate patient's suicide attempt, severity of depression and possibility of bipolar disorder. Results : Compared to non-high risk group, suicide high risk group showed significantly higher BDI(p<0.001) and intensity of ideation(IOI) in C-SSRS(p<0.001). Also intensity of ideation(IOI) was correlated with Mood Disorder Questionnaire(MDQ) bipolarity positive(p=0.033). Conclusions : The present study indicated that possibility of bipolar disorder plays a significant role in suicide attempters. Assessment of suicide ideation severity and possibility of bipolar disorder should be considered when suicide attempters come to emergency room.