• 대한한방내과학회지
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• 제22권3호
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• pp.495-501
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• 2001

Alcohol withdrawal syndrome includes two or more of the following symptoms: autonomic hyperactivity, increased hand tremor, insomnia, nausea or vomiting, hallucinations of illusions, psychomotor agitation, anxiety, grand mal seizures. Symptoms are usually relieved by administering brain depressant. In oriental medicine, Ju sang correspond to alcohol withdrawal syndrome. Galhwahaesung-tang has been used for the treatment of Ju sang. The authors treated 2 cases of alcohol withdrawal syndome with Galhwahaesung-tang and symptoms are markedly improved. So, We report these case with a brief review of related literatures.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제20권4호
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• pp.259-262
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• 2017

Mitochondria play essential role in eukaryotic cells including in the oxidative phosphorylation and generation of adenosine triphosphate via the electron-transport chain. Therefore, defects in mitochondrial DNA (mtDNA) can result in mitochondrial dysfunction which leads to various mitochondrial disorders that may present with various neurologic and non-neurologic manifestations. Mutations in the nuclear gene polymerase gamma (POLG) are associated with mtDNA depletions, and Alpers-Huttenlocher syndrome is one of the most severe manifestations of POLG mutation characterized by the clinical triad of intractable seizures, psychomotor regression, and liver failure. The hepatic manifestation usually occurs late in the disease's course, but in some references, hepatitis was reportedly the first manifestation. Liver transplantation was considered contraindicated in Alpers-Huttenlocher syndrome due to its poor prognosis. We acknowledged a patient with the first manifestation of the disease being hepatic failure who eventually underwent liver transplantation, and whose neurological outcome improved after cocktail therapy.

• Childhood Kidney Diseases
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• 제7권2호
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• pp.197-203
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• 2003

다양한 신경학적 이상을 동반한 소두증과 조기발현 신증군을 보이는 Galloway-Mowat 증후군은 치료반응이 불량하며 신기능의 저하가 진행되 조기에 사망하는 드문 유전성 질환이다. 임상적, 조직학적 다양성을 보이는 소두증과 신증후군을 동반한 일련의 질환군에 대해 아직 그 견해가 정립되지 않았고 향후 지속적인 연구가 이어질 것으로 생각되며 유전성 및 예후 등을 고려할 때 주목해야 할 필요가 있다고 생각되어 저자들이 경험한 소두증과 신경학적 이상을 동반한 조기발현 신증후군 1례를 보고하는 바이다.

• Journal of mucopolysaccharidosis and rare diseases
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• 제3권2호
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• pp.41-43
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• 2017

Prader-Willi syndrome (PWS) is a genetic disorder that is considered, especially on child, to cause poor feeding, hypotonia, failure to thrive, developmental delay and hypogonadism which is known to affect between 1 in 10,000 and 30,000 people. The children with PWS are viewed as affected by growth hormone (GH) insufficiency, although the exact mechanisms of GH deficiency are not fully understood. However, the benefits of GH treatment in children with PWS are well established. Myers, et al. (2006), Grugni, et al. (2016) indicated its positive effects on linear growth, body composition, motor function, respiratory function and psychomotor development. Despite of its effectiveness and advantages had been well known and proven in many other studies, there is only one recombinant GH product that is approved for PWS in Korea, $Genotropin^{(R)}$, till now. A phase III clinical study of GH treatment with $Eutropin^{TM}$, in 34 Korean PWS children is in progress, which is expected to have comparable effects and safety profile with the active control by assessing auxological changes such as height standard deviation score, body composition changes such as lean body mass and percent body fat, motor and cognitive development using Bayley scale, and safety profiles.

• 한국간호교육학회지
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• 제25권3호
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• pp.378-387
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• 2019

Purpose: This article is a comprehensive review for concept clarification of critical thinking, clinical reasoning, and clinical judgment, which still lack a consensus and are of mixed use. Methods: Norris's method of concept clarification was used to review concepts that have no clear definition or conceptualization yet. Results: This review summarized literature from various disciplines, classified each concept based on similarities and differences, and provided hypothetic conceptual schema. Conclusion: Clinical reasoning and clinical judgment are clinical situation specific concepts, while critical thinking is a concept applied in general situations. Critical thinking is a broader concept and serves as a foundation for clinical reasoning and clinical judgment. Clinical reasoning precedes clinical judgment. Clinical judgement implies the end point or conclusion of clinical reasoning. Each of critical thinking, clinical reasoning, and clinical judgment is a cognitive and affective process not a psychomotor process. The concept of clinical competency involves action taken after the cognitive processes of clinical reasoning and clinical judgment.

• Journal of mucopolysaccharidosis and rare diseases
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• 제4권2호
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• pp.42-44
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• 2018

Prader-Willi syndrome (PWS) is a multisystemic complex disorder characterized by hyperphagia and impaired satiety which lead to severe and early obesity. In infancy, hypotonia and poor suck are main problems, and a child goes through Failure-to-thrive. During childhood, clinical manifestations change to food seeking as well as excessive weight gain, short stature, developmental delay, cognitive disability and behavioral problems. Also, growth hormone insufficiency is frequent. Most patients receive the recombinant growth hormone (rGH) therapy that provides improvement in growth, body composition, and physical attributes. The clinical care guideline for rGH therapy in PWS had been noticed in 2013. The rGH therapy helps in body fat, lean body mass, height SDS and head circumference. Also, the rGH therapy helps motor function, psychomotor development and cognition and behavioral issues.In Samsung medical center, there are clinical care guidelines for rGH therapy in PWS and an useful application for the patients. 'Living with PWS', the name of an moblie application for PWS patients, was introduced in the lecture. The application revised to version 2. It was made more convenient to users than in version 1. It helps caregivers to schedule the rGH therapy and to monitor height and weight.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.695-704
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• 2021

This study aims to determine the effect of changes in learning systems and its effects on students' learning outcomes amid the Covid-19 pandemic. The sample of this study are the students who are in Jakarta, Indonesia. "Non-probability random sampling" technique has been used to select the samples while the sampling method used is "purposive sampling", where criteria are used to select samples. The samples in this study are 200 people taken randomly using Google Form. Concentration ability and learning interest can affect learning outcomes with the mediation of learning comfort and a good learning environment. As well as physical distancing can moderate the effect of concentration ability and learning interest on learning outcomes. The ability to concentrate on improving learning outcomes requires psychomotor improvement. Whereas interest in learning with indicators of learning awareness can improve learning outcomes. A clean environment is a strength in the learning comfort and the community environment can be recommended in the learning environment. The implementation of the restriction of gathering becomes an important point of physical distancing. The other novelties are the learning comfort and the learning environment as mediating variables and physical distancing as moderating variables in one study at a time.

• 대한치과의사협회지
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• 제58권11호
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• pp.670-682
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• 2020

This research examined the difference in cognitive load and the virtual presence depending on auditory feedback and task difficulty in haptic-based dental simulation. In the field of dental education, practice-centered training using handpiece has been crucial because a practitioner's psychomotor experience has a significant impact on the mastery of treatment skills. For the novice, it is necessary to reduce errors in dental treatment to enhancing skill acquisition in the haptic practice. In the training process, the force-feedback is crucial to elaborate subtle movement to guide what to do and how it should be hard or soft. However, It is not easy to add force-feedback to generate kinetic experience training. As an alternative method, we examined that auditory feedback can help learners' skill training. In this study, we analyzed how the presence/absence of auditory feedback at the different levels of task difficulty impacts learners' psychological demand and virtual presence in the virtual reality simulation. For this study, 29 dental college students participated in a dental simulation. The participants were grouped into two conditions that are with and without auditory feedback. Additionally, two consecutive tooth preparation tasks with different levels of difficulty were used in the simulation. The auditory feedback condition gives alarms to a learner when he treats a non-targeted tooth with a virtual handpiece. The user's cognitive load and virtual presence were measured to examine the effects of auditory feedback. The results revealed that the main effect was found in cognitive loads. Also, a significant interaction effect was shown in the virtual presence. We discussed the effective design methods for the virtual reality-based dental simulation through the result of this study.

• 정보교육학회논문지
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• 제24권1호
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• pp.1-10
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• 2020

4차 산업 혁명에 따라 전 세계에서는 이에 맞는 새로운 인재를 양성하고자 SW 교육을 강조하고 있다. 이런 세계적 흐름에 맞추어 우리나라에서도 2015 개정교육과정에서 SW 교육을 필수화하였다. 하지만 우리나라 초등 SW교육은 블록 기반 프로그래밍 언어의 활용에 편중되어 있다. 또한 목표 설정 및 내용 구성에 있어 정의적 영역의 신장은 소홀하고 지식, 기능적 영역의 신장에만 집중되는 경향이 있다. 이에 본 연구에서는 텍스트 기반 프로그래밍 언어 중에서 최근 각광받고 있는 파이썬과 정의적 영역인 '공동체 역량'의 신장을 고려하여 팀 공유정신모형 개념을 활용한 SW교육 방법을 탐구하였다. 팀 공유정신모형 형성 정도가 유사한 두 집단에 t-검정을 수행해 본 결과, 본 연구에서 제시한 SW학습방법을 적용한 집단 내 학습자들의 팀 공유정신모형 형성에 효과가 있다는 것을 확인할 수 있었다.

• 대한간호학회지
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• 제36권6호
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• pp.976-982
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• 2006

Purpose: The purpose of this study was to compare the feeling state guided imagery(FSGI) and end state guided imagery(ESGI) on stress and performance of an intramuscular injection of nursing students. Method: The design was a time series with a nonequivalent control group pretest-posttest study. Data was collected from the 23 rd to the 25th of Nov. 2004. The subjects of this study were 40 female sophomores (21 for the ESGI, 19 for the FSGI). The instruments used in this study were the Visual Analogue Scale for Stress and the Nursing Skill Performance Check-list on Intramuscular Injection developed by the researchers(10 items). Guided imagery was provided through audiotapes for 8 minutes. A pretest was given before applying the guided imagery, posttest 1 was performed after the intervention, posttest 2 was performed before the intramuscular injection and then evaluation of the performance of the intramuscular injection was done. Data was analyzed using t-test, and Repeated Measures ANOVA. Result: The level of stress for those who received the ESGI and FEGI was not significant and the level of the nursing skill performance for those who received the ESGI was significantly higher than that of students who received the FEGI. Conclusion: The use of ESGI has an effect on learning psychomotor nursing skills and further research is needed on stress.