• Title/Summary/Keyword: Protective effect

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Performance Research of a Multi Functional Tree Protection Pad (다목적 기능을 가진 수목보호패드의 성능 연구)

  • Jung, Yong-Jo;Lee, Kyung-Yeon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.21 no.1
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    • pp.133-143
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    • 2018
  • In spite of the growing importance of landscaping trees, the rate of flawed and withered trees damaged by pest, disease, drought or frost is increasing. In order to evaluate the performance of the Tree Protective Pad, which are developed to reduce the failure ratio in landscape planting, the tree protective pad for 'digging', 'pest controlling', and 'insulating' are tested based on the five functional criteria; moisturizing effect, wither preventive effect, pest and disease control, thermal effect, tensile strength, and environmental performance. The result of this study is as follows. The moisturizing effect of the tree protective pad for digging is found to be outstanding. According to the result of testing the pad on trees, in particular, it is better than jute tape in wither preventive effect, which means it is expected to prevent flaw and wilt from planting during the improper seasons like summertime. The experiment of installing the protective tree pad for pest controlling to the trunk of Quercus mongolica shows that preventive effect of the pad from diseases and insects is superior, and it also has economical effect by reducing the use of agricultural chemicals. The comparative test of the pad for insulating and jute tape proves that the temperature of the pad is about $2^{\circ}C$ higher than outside. The rate of tensile strength and biodegradation of the pad exceeds the optimal level, so it is revealed that the pad may be the work efficient and environment-friendly product. Likewise, by timely irrigating trees, the tree protective pad economically prevents trees from pest, disease,drought or frost, which may be caused by improper seasonal or delayed planting. As a means of reducing the flaw and facilitating the growth of trees, the exceptional performance of the pad is expected to effectively used in landscape planting and management.

Betula Platyphylla var. Japonica Extract Prevent Ultraviolet C Light-induced Cell Damage in Chinese Hamster Fibroblast (V79-4) Cells

  • Lee, Mi-Kyoung;Kim, Jeong-Hee
    • International Journal of Oral Biology
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    • v.33 no.4
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    • pp.137-141
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    • 2008
  • The present study reports the protective properties of a total methanol extract of B. platyphylla var. japonica against ultraviolet (UV)-C irradiation. Pretreatment of Chinese hamster fibroblast (V79-4) cells with a total methanol extract significantly increased cell survival following $300\;J/m^2$ of UV-C irradiation. The total methanol extract was further fractionated into 5 fractions: n-hexane, dichloromethane, ethylacetate, n-butanol and water fractions. Among these fractions, B. platyphylla var. japonica ethylacetate, butanol and water fractions showed significant protective effects against the cellular damage induced by UV-C irradiation. In order to elucidate the mechanism underlying this protective effect, DPPH (Editor note: abbreviations should be spelled out at first use.) radical scavenging and lipid peroxidation inhibitory activity were measured. Significant radical scavenging and lipid peroxidation inhibitory activities were observed for the ethylacetate fraction. In summary, the present data demonstrate that an extract of B. platyphylla var. japonica has a significant protective effect against UV-C irradiation. The underlying mechanism of this protective effect may involve radical scavenging and inhibition of lipid peroxidation by the B. platyphylla var. japonica extract.

Protective Effect of Processed Saengmaek-san(SM) on Cell Damage in UV-exposed HaCaT Cell (생맥산(生脈散)이 자외선에 의한 피부각질세포의 상해에 미치는 영향)

  • Kim, Eun-Seop;Yoo, Dong-Youl
    • The Journal of Korean Obstetrics and Gynecology
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    • v.24 no.2
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    • pp.33-51
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    • 2011
  • Objectives: This study was performed to assess the protective effect of Saengmaek-san (SM) on UVB-induced HaCaT cell damage. Methods: The protective effects of Saengmaek-san(SM) were determined by UVB-induced HaCaT assay. We assessed protective effects of Saengmaek-san (SM) on LDH release and nitrite release from HaCaT. And COX-2, Bcl-2, Bax, $TNF{\alpha}$, c-jun, c-fos, NF-kB, iNOS, Bcl-xL gene expression were determined in HaCaT using real-time PCR method. Results: 1. SM inhibited LDH-release, nitrite production in UVB-exposed HaCaT. 2. SM suppressed the gene expression of COX-2, $TNF{\alpha}$ in UVB-exposed HaCaT. 3. SM increased the gene expression of Bcl-2, Bax, Bcl-xL family protein in UVB-exposed HaCaT. 4. SM suppressed the gene expression of c-jun, c-fos, NF-kB in UVB-exposed HaCaT. Conclusions: The study showed SM inhibited the cell damage in UVB-exposed HaCaT.

Protective Effect of Crataegi Fructus Extract on the Neurotoxicity Induced by Reactive Oxygen Species in Cultured C6 Glioma Cell

  • Ha, Dae-Ho;Yoo, Sun-Mi
    • Biomedical Science Letters
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    • v.14 no.1
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    • pp.27-32
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    • 2008
  • To clerify the antioxidant effect of Crataegi Fructus (CF) extract on reactive oxygen species (ROS), The C6 glioma cells were treated with various concentrations of hydrogen peroxide ($H_2O_2$). The $H_2O_2$-induced neurotoxicity was measured by XTT assay for the cell viability. For the protective effect of CF extract on the cytotoxicity induced by $H_2O_2$, cell viability, lactate dehydroganase (LDH) activity, and the inhibitive activity of lipid peroxidation of CF extract were performed. In this study, $H_2O_2$ decreased cell viability dose- and time-dependent manners and increased LDH activity compared with the control. In the protective effect on $H_2O_2$, CF extract increased cell viability and decreased LDH activity on $H_2O_2$-induced cytotoxicity, lipid peroxidation by FTC assay. From these results, It is suggested that $H_2O_2$ was highly toxic on cultured C6 glioma cells, and also, CF extract showed the protective effect on $H_2O_2$-mediated cytotoxicity.

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PROTECTIVE EFFECT OF TAURINE ON INDOMETHACIN-INDUCED GASTRIC MUCOSAL INJURY

  • Miwon Son;Kim, Hee-Kee;Kim, Won-Bae;Junnick Yang;Kim, Byong-Kak
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.92-92
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    • 1995
  • It has been suggested that oxygen-derived free radicals have an important role in the pathophysiology of acute gastric ulceration induced by NSAIDs and ischemia-reperfusion. Taurine is hypothetized to exert its protective effect on NSAIDS-induced gastric injury by its antioxidant properties, Protect ive effect of taurine on indomethacin-induced gastric mucosal lesion and its protective mechanism were investigated. Intragastric administration of 25 mg/kg of indomethacin induced hemorrhagic lesions on the glandular stomach in rats, Pretreatment with 0.25 g/kg of taurine for 3 days significantly reduced the gastric lesion formation and Inhibited the elevation of lipid peroxide level In gastric mucosa. Both resting and FMLP-induced luminol-dependent chemiluminescence of rat peritoneal neutrophils increased immediately after treatment of indomethacin. 5-20mM of taurine inhibited chemiluminescence of neutrophils activated by indomethacin and/or FMLP. Human neutrophils (polymorphonuclear leukocytes) significantly adhered to confluent monolayer of human umbilical vein endothelial cells(HUVEC) after coincubation with aspirin or indomethacin. Also taurine prevented neutrophil adhesion induced by these drugs to HUVEC in dose-dependent manner. These results indicate that the protective effect of taurine against NSAIDS-induced gastric mucosal Injury is due to its antioxidant effect, which inhibits lipid peroxidation and neutrophil activation.

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Chemistry Study on Protective Effect against·OH-induced DNA Damage and Antioxidant Mechanism of Cortex Magnoliae Officinalis

  • Li, Xican;Fang, Qian;Lin, Jing;Yuan, Zhengpeng;Han, Lu;Gao, Yaoxiang
    • Bulletin of the Korean Chemical Society
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    • v.35 no.1
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    • pp.117-122
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    • 2014
  • As a Chinese herbal medicine used in East Asia for thousands years, Cortex Magnoliae Officinalis (CMO) was observed to possess a protective effect against OH-induced DNA damage in the study. To explore the mechanism, the antioxidant effects and chemical contents of five CMO extracts were determined by various methods. On the basis of mechanistic analysis, and correlation analysis between antioxidant effects & chemical contents, it can be concluded that CMO exhibits a protective effect against OH-induced DNA damage, and the effect can be attributed to the existence of phenolic compounds, especially magnolol and honokiol. They exert the protective effect via antioxidant mechanism which may be mediated via hydrogen atom transfer (HAT) and/or sequential electron proton transfer (SEPT). In the process, the phenolic-OH moiety in phenylpropanoids is oxidized to the stable quinine-like form and the stability of quinine-like can be ultimately responsible for the antioxidant.

Protective Effect of Taurine on Indomethacin-induced Gastric Mucosal Injury

  • Son, Miwon;Kim, Hee-Kee;Kim, Won-Bae;Yang, Junnick;Kim, Byong-Kak
    • Archives of Pharmacal Research
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    • v.19 no.2
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    • pp.85-90
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    • 1996
  • It has been suggested that oxygen-derived free radicals play an important role in the pathophysiology of acute gastric ulceration induced by NSAIDs and ischemia-reperfusion. Taurine is hypothetized to exert its protective effect on NSAIDs-induced gastric injury by its antioxidant properties. Protective effect of taurine on indomethacin-induced gastric mucosal lesion and its protection mechanism were investigated. Intragastric administration of 25 mg/kg of indomethacin induced hemorrhagic lesions on the glandular stomach in rats. Pretreatment with 0.25 or 0.5 g/kg of taurine one day before or for 3 days significantly reduced the gastric lesion formation and inhibited the elevation of lipid peroxide level in gastric mucosa. The luminol-dependent chemiluminescence of rat peritoneal neutrophils increased immediately after treatment of FMLP or indomethacin. Taurine (5-20 mM) inhibited chemiluminescence of neutrophils activated by FMLP. Human neutrophils (polymorphonuclear leukocytes) significantly adhered to the confluent monolayer of human umbilical vein endothelial cells (HUVEC) after coincubation with indomethacin. This neutrophil adhesion induced by indomethacin to HUVEC was prevented by taurine in a dose-dependent manner. These results indicate that the protective effect of taurine against NSAIDs-induced gastric mucosal injury is due to its antioxidant effect, which inhibits lipid peroxidation and neutrophil activation.

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The study on the school resilience of grandparent-grandchildren family adolescent through mediation effect of protective factor (보호요인의 매개효과를 통한 조손가족 청소년의 학교 적응유연성에 관한 연구)

  • Song, Yoo-Mee;Lee, Yun-Hyung
    • Korean Journal of Social Welfare Studies
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    • v.40 no.3
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    • pp.41-68
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    • 2009
  • Grandparent-grandchildren family adolescents(GGFAs) need to be well discussed because they tend to be more influenced by the negative surroundings than ordinary family adolescents. Over the past few years, several studies have been made on the correlation between the risk factor, the protective factor and the school resilience of GGFAs, but these studies have the limit to explain the only correlation between the one factor and the school resilience. So the purpose of this study was to examine not only the direct effect between the risk factor and the protective factor, but also the parametric path and effect that the one factor has influence on the correlation between the another factor and the school resilience of GGFAs. We investigated the 328 GGFAs in Korea, and the analytic method used was the Structural Equation Modeling(SEM). The followings are the results of this paper. It was found that the model adaptability had a considerable validity by inspecting the SEM, which showed not only the direct effect between the risk factor, protective factor and the school resilience of GGFAs, but also the mediation effect by the protective factor. The risk factors - the indifference of teacher, the negative attachment relationship, melancholy, uneasiness etc - had a negative influence on the school resilience of GGFAs. The protective factors - the supporss etteacher, self-esteem etc - had a positive influence on the school resilience of GGFAs. The protective factors were found to reduce the negative influence on the school resilience of GGFAs.

The Impact of Psychosocial Protective and Risk Factors on Problem Drinking among American Adolescents: Focused on Compensatory and Buffering Effects of Protective Factors (미국 청소년의 문제성 음주에 대한 심리사회적 보호변인과 위험변인의 역할 - 보호변인의 보상효과와 완충효과를 중심으로 -)

  • Kim, Young-Mi
    • Korean Journal of Social Welfare
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    • v.56 no.4
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    • pp.269-290
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    • 2004
  • The purpose of this study was to examine the impact of psychosocial protective and risk factors on problem drinking among American adolescents. In addition, this study investigated the compensatory and buffering effects of psychosocial protective factors. The sample consisted 4,362 10th graders taken from the Monitoring the Future Study 2002. This study performed the hierarchical regression analysis for data analyses. The main findings provided that friend influence, sensation-seeking, and tolerance of deviance had significant positive relationships with problem drinking as risk factors. This study also revealed that negative perception on drinking, parental bonding, school bonding, and prosocial activity had significant direct impacts in decreasing problem drinking, which explains the compensatory effect of protective factors. Additionally, this study showed that negative perception on drinking had a significant buffering effect moderating friend influence on adolescents' opportunities exposed to problem drinking. The results of this study suggest some practical implications for preventive intervention programs that target adolescent problem drinking.

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Effects of unconfined blast on strategic structures and its protective measures

  • Choubey, Bishwajeet;Dutta, Sekhar C.;Hussain, Md. Ahsaan
    • Structural Engineering and Mechanics
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    • v.84 no.2
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    • pp.167-180
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    • 2022
  • A strategic structure when exposed to direct hit of conventional bomb/projectile are severely damaged because of large amounts of energy released by the impact and penetration of bomb. When massive concrete slabs suffer a direct hit, the energy released during impact and penetration process are able to easily break up large mass of concrete. When over stressed under such impact of bombs, the concrete structure fails showing brittle behavioural nature. This paper is intended to study and suggest the protective measures for structures used for strategic application by adopting a means to dissipate the large quantum of energy released. To quantitatively evaluate the force, displacement and energy in such scenario, a fine numerical model of the proposed layered structure of different combinations was built in ANSYS programme in which tri-nitrotoluene (TNT) explosive was detonated at penetration depth calculated for GP1000 Lbs bomb. The distinct blast mitigation effect of the proposed structure was demonstrated by adopting various layers/barriers created as protective measures for the strategic structure. The calculated result shows that the blast effect on the structure is potentially reduced due to provision of buster slab with sand cushioning provided as protective measure to the main structure. This concept of layered protective measures may be adopted for safeguarding strategic structures such as Domes, Tunnels and Underground Structures.