• Title/Summary/Keyword: Protection Rate

Search Result 1,733, Processing Time 0.03 seconds

Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease

  • Choi, Joo-Hyung;Jeong, Kwiwan;Kim, Su-Mi;Ko, Mi-Kyeong;You, Su-Hwa;Lyoo, Young S.;Kim, Byounghan;Ku, Jin-Mo;Park, Jong-Hyeon
    • Journal of Veterinary Science
    • /
    • v.19 no.6
    • /
    • pp.788-797
    • /
    • 2018
  • In many countries, vaccines are used for the prevention of foot-and-mouth disease (FMD). However, because there is no protection against FMD immediately after vaccination, research and development on antiviral agents is being conducted to induce protection until immunological competence is produced. This study tested whether well-known chemicals used as RNA virus treatment agents had inhibitory effects on FMD viruses (FMDVs) and demonstrated that ribavirin showed antiviral effects against FMDV in vitro/in vivo. In addition, it was observed that combining the administration of the antiviral agents orally and complementary therapy with vaccines synergistically enhanced antiviral activity and preserved the survival rate and body weight in the experimental animals. Antiviral agents mixed with an adjuvant were inoculated intramuscularly along with the vaccines, thereby inhibiting virus replication after injection and verifying that it was possible to induce early protection against viral infection prior to immunity being achieved through the vaccine. Finally, pigs treated with antiviral agents and vaccines showed no clinical signs and had low virus excretion. Based on these results, it is expected that this combined approach could be a therapeutic and preventive treatment for early protection against FMD.

Comparative Estimation of Exposure Level and Health Risk Assessment of Highly Produced Pesticides to Agriculture Operators by Using Default Dermal Absorption Rate or Actual Measurement Values

  • Kim, Su-Hyeon;Lee, Chang-Hun;Kim, Ki-Hun;Jeong, Sang-Hee
    • Biomedical Science Letters
    • /
    • v.22 no.4
    • /
    • pp.199-206
    • /
    • 2016
  • Pesticides are widely used to prevent loss of agricultural production but extensive exposure can induce health problems to pesticide operators. This study was performed to evaluate the health risk of highly produced pesticides used in fruit growing farm land by comparison of estimated exposure level with AOEL using KO-POEM program. AOEL was driven based on NOAEL of each pesticide evaluated by JMPR, EFSA or KRDA. In calculation of exposure level, types of formulation, dilution factors, spraying duration and motor type and exposure protection device were allocated according to actual condition of use. Dermal absorption rate was differently applied among EFSA default values (25% or 75%), general default value (10%) or real test result values to know the plausibility of default values and safety of pesticide to operators in outline. Twenty pesticide ingredients (fungicides and insecticides) were produced more than 30 tons per year, which were mancozeb, chlorothalonil, imidaclopirid and etc in order. Dermal absorption rates obtained from studies were various from 0.07 to 81% but mostly under 10%. The estimated exposure levels showed big differences more than 10 times higher when using EFSA default rate and up to 5 times higher when using general rate of 10% comparing using rates of test results. Mancozeb, chlorthalonil, diazinon and chlorpyrifos presented still higher exposure level than AOEL even when using test absorption rate from study, which suggests that re-evaluation of AOEL or dermal exposure absorption rate or strict management are required for health protection of operators who use those four pesticides in farm land.

A Review of Dose Rate Meters as First Responders to Ionising Radiation

  • Akber, Aqeel Ahmad;Wiggins, Matthew Benfield
    • Journal of Radiation Protection and Research
    • /
    • v.44 no.3
    • /
    • pp.97-102
    • /
    • 2019
  • Background: Dose rate meters are the most widely used, and perhaps one of the most important tools for the measurement of ionising radiation. They are often the first, or only, device available to a user for an instant check of radiation dose at a certain location. Throughout the world, radiation safety practices rely strongly on the output of these dose rate meters. But how well do we know the quality of their output? Materials and Methods: This review is based on the measurements 1,158 commercially available dose rate meters of 116 different makes and models. Expected versus the displayed dose patterns and consistency was checked at various dose rates between $5{\mu}Gy{\cdot}h^{-1}$ and $2mGy{\cdot}h^{-1}$. Samples of these meters were then selected for further investigation and were exposed to radiation sources covering photon energies from 50 keV to 1.5 MeV. The effect of detector orientation on its reading was also investigated. Rather than focusing on the angular response distribution that is often reported by the manufacturer of the device, this study focussed on the design ergonomics i.e. the angles that the operator will realistically use to measure a dose rate. Results and Discussion: This review shows the scope and boundaries of the ionising radiation dose rate estimations that are made using commonly available meters. Observations showed both inter and intra make and model variations, occasional cases of instrument failure, instrument walk away, and erroneous response. Conclusion: The results indicate the significance of selecting and maintaining suitable monitors for specific applications in radiation safety.

Dose Estimation Model for Terminal Buds in Radioactively Contaminated Fir Trees

  • Kawaguchi, Isao;Kido, Hiroko;Watanabe, Yoshito
    • Journal of Radiation Protection and Research
    • /
    • v.47 no.3
    • /
    • pp.143-151
    • /
    • 2022
  • Background: After the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, biological alterations in the natural biota, including morphological changes of fir trees in forests surrounding the power plant, have been reported. Focusing on the terminal buds involved in the morphological formation of fir trees, this study developed a method for estimating the absorbed radiation dose rate using radionuclide distribution measurements from tree organs. Materials and Methods: A phantom composed of three-dimensional (3D) tree organs was constructed for the three upper whorls of the fir tree. A terminal bud was evaluated using Monte Carlo simulations for the absorbed dose rate of radionuclides in the tree organs of the whorls. Evaluation of the absorbed dose targeted 131I, 134Cs, and 137Cs, the main radionuclides subsequent to the FDNPP accident. The dose contribution from each tree organ was calculated separately using dose coefficients (DC), which express the ratio between the average activity concentration of a radionuclide in each tree organ and the dose rate at the terminal bud. Results and Discussion: The dose estimation indicated that the radionuclides in the terminal bud and bud scale contributed to the absorbed dose rate mainly by beta rays, whereas those in 1-year-old trunk/branches and leaves were contributed by gamma rays. However, the dose contribution from radionuclides in the lower trunk/branches and leaves was negligible. Conclusion: The fir tree model provides organ-specific DC values, which are satisfactory for the practical calculation of the absorbed dose rate of radiation from inside the tree. These calculations are based on the measurement of radionuclide concentrations in tree organs on the 1-year-old leader shoots of fir trees. With the addition of direct gamma ray measurements of the absorbed dose rate from the tree environment, the total absorbed dose rate was estimated in the terminal bud of fir trees in contaminated forests.

Study on the Determination of Fire Protection Thickness based on Section Factor (강재의 단면형상에 따른 내화피복두께 산정 연구)

  • 정청운;지남용;권인규
    • Proceedings of the Korean Institute of Building Construction Conference
    • /
    • 2003.05a
    • /
    • pp.139-142
    • /
    • 2003
  • Traditionally, the thickness of fire protection materials of structural elements such as beam and column have been decided by fire test using the predominant steel section of $H-300{\times}300{\times}10{\times}15$ for column and $H-400{\times}200{\times}8{\times}13$ for beam in Korea. But this way of determination of fire protection thickness yields very unduly results. Because the temperature-increment rate of structural steel elements depends mainly on magnitude of their cross-areas. In general, the thicker size of cross-areas for structural elements, the lower temperature shows up. It had already proved that the fire protection thickness only depends on the size of cross-areas and the fire protection method for three-fide or four-side exposed conditions in European countries, the United State of America and so on. To demonstrate there would be differences among various cross-areas for structural elements, we conducted several fire tests with full-scale specimens of beams and columns. For the determination of critical temperature for steel section when the fire resistant performance is needed to be decided, we conducted with a loaded fire test for beam and column, respectively. The small column in 1.0 meter length and beam in 1.5 meter length were used in order to deprive the rational fire protection thickness of structural elements such as beam and column, respectively. After test, we could obtain there were significant temperature lass between higher cross-areas and lower cross-areas. The critical temperature of steel as a criterion is used 538$^{\circ}C$ for column and 593$^{\circ}C$ for beam which is from ASTM E 119 because we don't make provisions as critical temperature by elements. We could consider that the best way of determination of fire protection thickness is using the following multi-regression equation which was deprived from several fire tests using the concept of section factor, FR(column) = 0.17 +5191.49t A/Hp + 40.77t, FR(beam) = 0.25 +6899.31t A/Hp + 32.60t(where, FR means fire resistant time, t means thickness, A means cross-area and Hp means heated parameter).

  • PDF

Evaluation of Respiratory Protection Program in Petrochemical Industries: Application of Analytic Hierarchy Process

  • Kolahi, Hadi;Jahangiri, Mehdi;Ghaem, Haleh;Rostamabadi, Akbar;Aghabeigi, Mandana;Farhadi, Payam;Kamalinia, Mojtaba
    • Safety and Health at Work
    • /
    • v.9 no.1
    • /
    • pp.95-100
    • /
    • 2018
  • Background: Respiratory protection equipment (RPE) is the last resort to control exposure to workplace air pollutants. A comprehensive respiratory protection program (RPP) ensures that RPE is selected, used, and cared properly. Therefore, RPP must be well integrated into the occupational health and safety requirements. In this study, we evaluated the implementation of RPP in Iranian petrochemical industries to identify the required solutions to improve the current status of respiratory protection. Methods: This cross-sectional study was conducted among 24 petrochemical industries in Iran. The survey instrument was a checklist extracted from the Occupational Safety and Health Administration respiratory protection standard. An index, Respiratory Protection Program Index (RPPI), was developed and weighted by analytic hierarchy process to determine the compliance rate (CR) of provided respiratory protection measures with the RPP standard. Data analysis was performed using Excel 2010. Results: The most important element of RPP, according to experts, was respiratory hazard evaluation. The average value of RPPI in the petrochemical plants was $49{\pm}15%$. The highest and lowest of CR among RPP elements were RPE selection and medical evaluation, respectively. Conclusion: None of studied petrochemical industries implemented RPP completely. This can lead to employees' overexposure to hazardous workplace air contaminants. Increasing awareness of employees and employers through training is suggested by this study to improve such conditions.

A Study on Protection Performance of Radiation Protective Aprons classified by Manufacturers and Lead Equivalent using Over Tube Type Fluoroscopy (Over Tube Type의 투시촬영장치를 이용한 제조사별, 납당량별 엑스선방어 앞치마의 Protection 성능 평가에 관한 연구)

  • Song, Jong-Nam;Seol, Gwang-Wook;Hong, Seong-Il;Choi, Jeong-Gu
    • Journal of the Korean Society of Radiology
    • /
    • v.5 no.3
    • /
    • pp.135-141
    • /
    • 2011
  • If protective performance of apron cannot be good, radiation exposure of an guardian or a patient, a person engaged in radiation related industry cannot rise. Therefore, It will be evaluated protection performance to radiation protection aprons by manufacturers and lead equivalent more than 0.25mm lead equivalent. And, will show in the direction of application to clinic. The new aprons by manufacturers(H, X, I, J company) and lead equivalent(0.50mmPb, 0.35mmPb, 0.25mmPb) measured transmitted dose rate and shielding rate, uniformity under fluoroscopy and general radiography using to fluoroscopy system and digital radiography system, x-ray multifunction meter. The shielding rate measurement results, 0.5mmPb apron was Shielding rate of apron of a I company(fluoroscopy : 97.96%) was the best under six companies, and shielding rate of apron of a J company(fluoroscopy : 96.25%) was worst. 0.35mmPb Apron was Shielding rate of a I company(fluoroscopy : 96.79%) was the best under the three companies, and shielding rate of an H company(fluoroscopy : 95.81%) was the worst. 0.25mmPb Apron was Shielding rate of X company apron(fluoroscopy : 90.908%) was better than H company apron(fluoroscopy : 88.82%) than two companies. The uniformity measurement results, 0.5mmPb Aprons of X company(fluoroscopy : 0.13) and I company(fluoroscopy : 0.19) was the best under the six companies, and J company apron(fluoroscopy : 0.45) was the worst. 0.35mmPb. Along a manufacturer and lead equivalent performance of apron protection is distinguished certainly. Therefore, a patient, guardian or a person engaged in radiation related industry shall enforce experiment of a lot of ways defined or evaluation so that the maximum reduces radiation exposure. Buy the apron that protective performance is good, It will be performed through experiment and evaluation.

A study on Rate Making Scheme of Korean Hull Insurance Rate in Preparation for the Opening of Hull Insurance Market (선박보검시장의 개방에 대비한 우리나라 선박보검기준 산정방안에 관한 연구)

  • 김형건
    • Journal of the Korean Institute of Navigation
    • /
    • v.18 no.3
    • /
    • pp.31-49
    • /
    • 1994
  • In the meantime Korean Insurance Industry has been developed a steady growth under government's political protection. But insurance market seems to be opened unavoidably owing to the liberalization of international trade by the Agreements of UR and the bloc of economy by EC Integration and the Organization of NAFTA. By the above reason, especially, in case of hull insurance, the rate of hull insurance is being instituted as a problem. Accordingly the recognition for the problem like this, in thsi study, explained the major objectives of rate making and described the basic rate making methods that are used in property and liability insurance, and searched the rate making schemes of hull insurance rate of the major nations by comparing method. And as a conclusion, the writer presented several schemes including new rate making scheme of hull insurance rate and the security of statistical data about loss ratio, and the establishment of Korean Hull Insurance Association.

  • PDF

Dyeing Properties and Functionality of Cotton Dyed with Extract from Spirodela polyrhiza and Mixture Extracts from Spirodela polyrhiza and Salvia plebeia R. Br. (개구리밥 추출물 및 개구리밥과 곰보배추 혼합 추출물로 염색한 면직물의 염색성 및 기능성)

  • Jung, Jin-Soun;Jang, Hyun-Joo
    • Fashion & Textile Research Journal
    • /
    • v.18 no.6
    • /
    • pp.869-877
    • /
    • 2016
  • This study looks into the dyeing properties and functionality of cotton fabrics dyed in both the Spirodela polyrhiza extract and the extract resulting from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza. Since the UV-Vis Spectrum of the methanol extract of Spirodela polyrhiza shows absorption peaks at 256, 268nm, and 345nm, it can be inferred that the compound that Spirodela polyrhiza contains is a flavonoid. In addition, it can also be presumed that, by analyzing the infrared absorption spectrum of Spirodela polyrhiza, the plant contains flavonoid compounds, just like Salvia plebeia R. Br.. The UV protection factors of the cotton fabrics dyed in both the Spirodela polyrhiza extract and the extract from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza were 50+, presenting outstanding UV protection factors. The deodorization rate of the cotton dyed in the Spirodela polyrhiza extract was between 30 and 120 minutes, and the rate rose from 92% to 97% as time passed. The deodorization rate of the cotton dyed in the extract from the mixture of Salvia plebeia R. Br. and Spirodela polyrhiza increased from 88% to more than 91%. The result also revealed that overall the fastness of color, including color fastness to washing related to change in color, as well as the color fastness to light of the fabric dyed in the extract from the mixture of the two plants improved, compared to the cloth dyed only in Spirodela polyrhiza extract. Furthermore, the antibacterial activity was also strengthened.