• 생약학회지
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• 제44권2호
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• pp.188-192
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• 2013

Acer tegmentosum which is belongs to Aceraceae has been widely used as a traditional medicine for the treatment of lots of diseases including pain management. In this study, we evaluated the anti-nocicepitve effects of methanolic extract of A. tegmentosum (MAT) in mice using various pain models. MAT presented strong and dose-dependent anti-nociceptive activities on thermal nociception models such as tail-immersion test and hot plate test. Moreover, acetic acid-induced chemical nociception was signigicantly reduced by MAT treatment. We could confirm MAT's central and peripheral analgesic properties by formalin test. We also found that the pre-treatment of opioid receptor antagonist did not alter the MAT's anti-nociception, suggesting opioid receptor is not involved in analgesic activity of MAT. Based on our results, we could conclude that MAT may be possibly used as an anti-nociceptive agent for the treatment of various nociceptive pains.

• 한국의학물리학회지:의학물리
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• 제17권3호
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• pp.167-172
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• 2006

전산화단층촬영에서 조영 증강을 위한 조영제 주입은 정맥내에 삽입한 카테터를 통해 자동주입기로 주입하고 있다. 정맥내에 위치한 카테터를 제거하는 도중에 IV 카테터가 부러져 정맥내에 남아 있는 카테터의 조각은 환자에게 순환기 질환의 위험을 초래할 수 있다. CT 검사 중에 정맥내에 카테터 조각이 남아있는 2명의 환자를 대상으로 카테터의 크기 및 위치를 정확히 확인하기 위해 MDCT를 이용하여 정맥내 주사부위를 스캔하였다. 3D 재구성은 MPR, MIP, 볼륨렌더링, SSD 등으로 구성하였다. 정맥내에 위치한 카테터 조각을 MDCT로 스캔한 데이터를 3D 재구성으로 정맥내의 위치 및 크기를 확인하였고, 카테터 조각을 제거하는데 일조하였다.

• 대한소아치과학회지
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• 제34권3호
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• pp.519-525
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• 2007

과잉치는 정상 치판의 과도한 증식의 결과로 발생하고, 주로 상악 전방부에서 많이 발견되며 이것을 정중과잉치라 칭한다. 정중과잉치의 존재 시 영구 전치의 위치 이상, 정중이개, 낭종의 형성, 구강 및 비강 내로의 맹출 등과 같은 다양한 문제가 존재하게 되므로 발거하는 것이 일반적이다. 본 증례는 외상으로 인해 편측 상악 중절치를 조기에 상실하였고, 매복된 상악 정중과잉치를 가지고 있는 9세 8개월된 남아로, 정중과잉치를 상실된 상악 중절치 부위에 자가이식한 후 보철적으로 수복하여 치조골 흡수를 막고 심미적인 수복을 도모한 증례이다. 이 증례에서 과잉치는 총 길이 14mm로 지대치로 사용하기에는 크기가 작고 치관/치근 비율도 좋지 않아 예후가 불량할 것으로 예상하였으나, 시술 후 8개월의 관찰 기간 동안 양호한 결과를 나타내어 이에 보고하는 바이다.

• 구강회복응용과학지
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• 제17권4호
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• pp.275-282
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• 2001

Centric relation is defined the horizontal position between maxilla and mandible when condylar head of mandible is positioned adequately in mandibular fossa. The most recent concept of centric relation position is defined as the mandibular position in which the condyles are in their most superoanterior position in the articular fossa, resting against the posterior slope of the articular eminences, with the articular disk properly interposed. To be suitable as a reference point during occlusal management, a mandibular position of centric relation has to be functionally acceptable to the patient and clinically reproducible and achievable during everyday practice. There are numerous methods for determination of centric relation, and in this study we used three of them, Gothic arch tracing(Group I), leaf gauge(Group II), and anterior jig(Group III). The subjects were 10, 8 men and 2 women, age-ranged from 23 to 26 years old, had no prosthetics in thier mouth, and had no sign and symptom of temporomandibular disorders. We gained three occlusal records using each method, and then the degree of the reproducibility was examined with split cast technique. In this study the reproducibility of centric relation using split cast technique was greater in the order of Group I(mean 1.6), Group II(mean 1.4), and Group III(mean 1.3), but there was no significant differences among them statistically(p>0.05).

• 한국전문물리치료학회지
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• 제11권3호
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• pp.43-50
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• 2004

This study was designed to determine the effects of different widths in the base of support (BOS) on trunk and lower extremity muscle activation during upper extremity exercise. Twenty-seven healthy male subjects volunteered for this study. Exercises were performed for a total of 10 trials with a load of 10 repetitions maximum (10 RM) for each of the various widths of BOS (10 cm, 32 cm, 45 cm). The width of a BOS is the distance between each medial malleoli when a subject was in a comfortable standing position. Electromyography was used to determine muscle activation. Surface bipolar electrodes were applied over the tibialis anterior, medial gastrocnemius, biceps femoris, rectus femoris, gluteus maximus, upper rectus abdominis, and elector spinae muscle. Electromyographic (EMG) root mean square (RMS) signal intensity was normalized to 5 seconds of EMG obtained with a maximal voluntary isometric contraction (MVIC). The data were analyzed by atwo-factor analysis of variance (ANOVA) with repeated-measures ($3{\times}7$) and Bonferroni post hoc test. The results were as follows: (1) There were significant differences in the width of the BOS (p=.006). (2) The post hoc test showed significant differences with the BOS between 10 cm and 32 cm, between 10 cm and 45 cm and between 32 cm and 35 cm (p=.008, p=.003, p=.011). (3) There was no interaction with the BOS and muscle. (p=.438) There were no significant differences in the muscle activation (p=.215).

• Natural Product Sciences
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• 제21권2호
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• pp.128-133
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• 2015

Lindera obtusiloba has been widely used as a traditional medicine for the treatment of lots of diseases, including abdominal pain, bruise, and hepatocirrhosis. Here in this study, we elucidated the lifespan-extending effect of methanolic extract of Lindera obtusiloba (MLO) using Caenorhabditis elegans model system. We found that MLO has potent lifespan extension activities under normal culture condition. Then, we determined the protective effects of MLO on the stress conditions such as osmotic, thermal and oxidative stress. To reveal possible mechanism of MLO-mediated lifespan, we further investigated the effect of MLO on the antioxidant enzyme activities and intracellular ROS levels. Our results demonstrated that superoxide dismutase and catalase activities were significantly up-regulated by MLO treatment, resulted in reduced intracellular ROS levels. In this work, we also tested whether MLO-mediated longevity activity was associated with aging-related factors such as food intake and growth. Our data revealed that both of pharyngeal pumping rate and body length were significantly shifted by MLO treatment, indicating these factors were involved in MLO's lifespan-extension effects. Although MLO induces reduction in food intake, the body movement of MLO-fed aged worms was not decreased, compared to untreated control worms, indicating MLO might extend lifespan without affecting healthspan.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제28권6호
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• pp.590-594
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• 2006

Dental implant has become one of the important option for completely or partially edentulous patients, But it is challenging to reconstruct the severely atrophic ridge. Insufficient bone volume could restrict to place the wide and long implant and because of excessive interocclusal clearance, improper prosthetics could be produced. In this case bone augmentation for implant dentistry is necessary procedure to improve the insufficient bone volume. Therefore, bone augmentation or GBR is the most important procedure for successful implant placement and for ideal crown- root ratio. There are various bone augmentation techniques have been introduced recently; like block bone graft, distraction osteogenesis, inlay graft, onlay graft, etc.... In severe bucco-lingual resorption area, ridge splitting is the first choice of the treatment, because it provides a place for implantation and also has compaction effect. This technique may be indicated for sharp mandible and maxillary ridges in patients whose bone quantity is inadequate for primary stabilization. We report that the clinical experience of bone augmentation using ridge splitting technique in bucco-lingual bone resorption area.

• 대한족부족관절학회지
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• 제12권1호
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• pp.41-46
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• 2008

Purpose: This study was designed to evaluate characteristics of foot pressure distribution with or without partial prosthetic foot in transmetatarsal amputee. Materials and Methods: The subjects were 9 transmetatarsal amputees. Foot pressures were measured at hallux, the $1^{st}-5^{th}$ metatarsal head (MTH), mid-foot, condyle area by F-scan system in amputated or contralateral foot during active walking. Results: In amputated foot, mean peak pressure was greatest in midfoot without prosthetic foot but it was greatest in hindfoot with prosthetic foot. In unaffected foot, although mean peak pressure was higher in hallux, and $1-5^{th}$ MTH compared to amputated foot, it was greatest in hind foot both with and without prosthetic foot. However, in unaffected foot, mean peak pressure significantly decreased in hallux and $5^{th}$ MTH after wearing the prosthetic foot. There was a significant difference in mean peak pressure in hallux and $5^{th}$ MTH between amputated and unaffected foot after wearing prosthetic foot. However, other region had no significant difference with or without prosthetic foot between feet. Conclusions: The use of partial prosthetic foot tends to shift weight bearing from the heel area to forefoot and could significantly reduce hind foot peak pressure and redistributed to peak pressure. The partial prosthetic foot can also offer the peak pressure to reduction both amputated foot and unaffected foot and help to toe off during walking.

• 한국콘텐츠학회논문지
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• 제14권5호
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• pp.281-288
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• 2014

본 연구는 울산시에 소재하는 H기업 예비군 동원훈련에 참여한 307명을 대상으로 보철물(틀니, 브릿지)과 임플란트 기대 수준에 대한 인식을 조사하고, 환자교육 및 상담에 기초자료로 활용하고자 한다. 보철물 기대수준의 신뢰도 cronbach'${\alpha}$는 .971, 임플란트 기대수준의 신뢰도 cronbach'${\alpha}$는 .967로 높게 나타났고 자료의 분석은 IBM SPSS Statistics. v. 19.0 프로그램을 이용하였으며, 유의수준은 0.05로 고려하였다. 연구결과는 첫째, 보철물 기대수준은 평균 3.98점으로 나타났다. 둘째, 임플란트 기대수준은 평균 3.74점으로 나타났다. 셋째, 주관적 건강상태에 따른 임플란트 기대수준은 평균 3.74점으로 나타났고 통계적으로 유의하였다(p=0.003). 넷째, 구강위생관리 관심정도에 따른 임플란트 기대수준의 차이는 평균 3.74점으로 나타났고 통계적으로 유의하였다(0<0.001). 다섯째, 보철물 기대수준과 임플란트 기대수준은 0.392로 강한 양의 상관관계를 나타났다. 위의 결과로 보철과 임플란트에 대한 정확한 정보전달이 필요하다.

• The Journal of Korean Physical Therapy
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• 제24권6호
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• pp.409-413
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• 2012

Purpose: Rehabilitative devices are used to enhance sensorimotor training protocols, for improvement of motor function in the hemiplegic limb of patients who have suffered a stroke. Sensorimotor integration feedback systems, included with these devices, are very good therapeutic frameworks. We applied this approach using electrical stimulation in stroke patients and examined whether a functional electric stimulation-assisted biofeedback therapy system could improve function of the upper extremity in chronic hemiplegia. Methods: A prototype biofeedback system was used by six subjects to perform a set of tasks with their affected upper extremity during a 30-minute session for 20 consecutive working days. When needed for a grasping or releasing movement of objects, the functional electrical stimulation (FES) stimulated the wrist and finger flexor or extensor and assisted the patients in grasping or releasing the objects. Kinematic data provided by the biofeedback system were acquired. In addition, clinical performance scales and activity of daily living skills were evaluated before and after application of a prototype biofeedback system. Results: Our findings revealed statistically significant gradual improvement in patients with stroke, in terms of kinematic and clinical performance during the treatment sessions, in terms of manual function test and the Purdue pegboard. However, no significant difference of the motor activity log was found. Conclusion: Hemiplegic upper extremity function of a small group of patients with chronic hemiparesis was improved through two weeks of training using the FES-assisted biofeedback system. Further research into the use of biofeedback systems for long-term clinical improvement will be needed.