• Title/Summary/Keyword: Project risk

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American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in ApcMin/+ mice

  • Yu, Chunhao;Wen, Xiao-Dong;Zhang, Zhiyu;Zhang, Chun-Feng;Wu, Xiaohui;He, Xin;Liao, Yang;Wu, Ningning;Wang, Chong-Zhi;Du, Wei;He, Tong-Chuan;Yuan, Chun-Su
    • Journal of Ginseng Research
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    • v.39 no.3
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    • pp.230-237
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    • 2015
  • Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered $Apc^{Min/+}$ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10-20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-$1{\alpha}$ (IL-$1{\alpha}$), IL-$1{\beta}$, IL-6, tumor necrosis factor-${\alpha}$, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

An Empirical Analysis on the Production and Price Effect by Agricultural Disaster Insurance (농업재해보험의 생산량 및 가격 효과에 관한 실증분석)

  • Han, Sungmin
    • KDI Journal of Economic Policy
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    • v.36 no.4
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    • pp.135-169
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    • 2014
  • This study empirically analyzes changes in production patterns of farmers by agricultural disaster insurance. The aim of this project is to achieve stability of farm management by paying insurance in case of a natural disaster. However, it causes farmers to change production patterns in the direction of increasing production, and leads the crop price to drop. This can be explained by producers' risk reduction through the disaster insurance. The empirical analysis is based on IV approach with using two stage least squares method. The first stage estimates by difference-in-differences methodology indicate that the production of insurable crops increases more about 80,000ton on average than that of non-insurable crops. In addition, to solve the endogeneity problem caused by general supply and demand model, I use the first stage estimates and find that the price index of the crops drops about 2.3% according to the production increase by 10,000ton. The credibility of these results is also attained by various robustness checks. These findings suggest that it is necessary for government to analyze the whole economy which consists of producer and consumer welfare when it determines the policy. Besides, it implies that it is essential to develop a new market to cope with the unintended effect.

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A Study on the Inventory Estimation for the Activated Bioshield Concrete of KRR-2 (연구로 2호기 방사화 수조 콘크리트의 재고량 평가에 관한 연구)

  • Hong, Sang Bum;Seo, Bum Kyoung;Cho, Dong Keun;Jeong, Gyeong Hwan;Moon, Jei Kwon
    • Journal of Radiation Protection and Research
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    • v.37 no.4
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    • pp.202-207
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    • 2012
  • The radioactivity inventory significantly affects all steps of decommissioning projects including planning, cost estimation, risk assessment, waste management and site remediation. The decommissioning project of the KRR-2 was completed in 2009 and a large amount of activated concrete waste was generated. The bioshield concrete, containing minute amount of impurity elements, was activated by neutron reaction during the operation of the reactor. A variety radionuclides was generated in the concrete, including $^3H$, $^{14}C$, $^{55}Fe$, $^{60}Co$ $^{63}Ni$, $^{134}Cs$, $^{152}Eu$ and $^{154}Eu$. In this paper, the comparison between the calculated results and previous measured results was carried out to estimate the inventory of the bioshield concrete of the KRR-2. The combined computer codes of MCNP5 and ORIGEN 2.1 for calculation of the distribution of neutron flux, cross-section and generation of radionuclides were used. The results were shown that 99.8% of the total radioactivity of $^3H$, $^{55}Fe$, $^{60}Co$ and $^{152}Eu$ in the bioshield concrete 12 years after shutdown. The effects on the variation of inventory were analysed depending on the operation periods and the cooling times in the bioshield concrete.

The Study on the Economic Appraisal of Fishing Port Investments (어항투자사업의 경제성 평가에 관한 연구)

  • 정형찬
    • The Journal of Fisheries Business Administration
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    • v.14 no.2
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    • pp.15-68
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    • 1983
  • From the economic point of view the fishing port is the complex of installations on land, organized to serve the fishing fleet and its cargo, and is the main link in the production chain of all components of the fishing industry, with the aim of achieving the planned targets with the minimum cost. Fishing port investment decisions have had significant impact on the development aims of Korean fisheries. Fishing port investments in Korea are made mostly by public or semipublic port authorities. Such investments should be judged not purely on the basis of financial profitability but rather on the extent to which they serve the development aims of the fishing industry. This makes the economic appraisal process more complex and presents certain problems in correctly quantifying the economic costs and benefits of the fishing port projects. This study concentrates more on the theoretical economic appraisal models than on the purely financial aspects of fishing port investments and points out the difference between the two approaches. In the result, there is clearly an element of judgment as to whether or not a shadow price needs to be used in estimating economic benefits and costs. From this viewpoint, some attempts are made to provide definitions of the possible economic benefits and costs, and methods for estimating and evaluating them in Part III and IV. Especially queueing theory is applied in the calculation of economic benefits. When a project is contemplated and analysis shows it to Lave a positive NPV, one question that arises is whether it should be implemented now or delayed. In this paper, the first year rate of return method is regarded as a more concise way of solving the timing of investment, At the end of Part IV, risk analysis of fishing port investments is considered. It can be handled in a number of ways, ranging from informal judgment to complex statistical analyses involving large-scale computer models, This paper recommends that evaluators of fishing port investments use the sensitivity analysis indicating exactly how much NPV will change in response to a given change in an input variable, other things held constant. Decisions regarding the amount of capacity to provide must be made in fishing port investments. Providing too much service would involve excessive capital costs. On the other hand, not providing enough service capacity would cause the waiting line of fishing vessels to become excessively long at times. Therefore, in Part V, the optimal number of berths and berth productivity in fishing port are defined as follows: Minimize E(TC) = E(WC)+E(SC) The minimum of this function is the solution and that is the optimal number of berth and berth productivity in fishing port.

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A Research on Partnership between General contractor and Specialist trades (일반.전문건설업체간의 협력관계에 대한 설문 분석)

  • Kim, Myung-Un;Lee, Jong-Sik;Lee, Jea-Sauk;Chun, Jae-Youl
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.587-590
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    • 2008
  • Typically, General contractor in the construction industry can not plan their own of the amount of orders received, and because of the size of wide fluctuations in the amount of annual orders received for equipment or personnel to full-time employment has limits. Therefore, with a vertical division of labor between specialist trades which distributed the risk and the intention to improve the efficiency of production will be. For this reason, the production structure of the general subcontracting relationships are formed. In this way, Depending on the structure of production outsourced management of the project is the impact on the successful completion. Nevertheless, most construction companies do not achieve effective an organized cooperation until now. This study is to understand the actual conditions an organized cooperation between general contractor and specialist trades, and is look at ways to improve with find the complement. This paper is a preliminary study of the leading research based on the present condition of the cooperating companies considered to be the cause. A result of Analysis, the actual conditions in cooperation of the construction industry is staying in an external form of organizational cooperation And were not effective utilization of the organization for the cooperation a production. Specialist trades have had to register as partners for the amount of orders received, the level of practical cooperation was almost no activity to improve a production. in each step an organized cooperation in the construction industry, to improve productivity construction and to create of economic value for the cooperation of production is required.

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Assessment factors for the Selection of Priority Soil Contaminants based on the Comparative Analysis of Chemical Ranking and Scoring Systems (국내.외 Chemical Ranking and Scoring 체계 비교분석을 통한 우선순위 토양오염물질 선정을 위한 평가인자 도출)

  • An, Youn-Joo;Jeong, Seung-Woo;Kim, Tae-Seung;Lee, Woo-Mi;Nam, Sun-Hwa;Baek, Yong-Wook
    • Journal of Soil and Groundwater Environment
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    • v.13 no.6
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    • pp.62-71
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    • 2008
  • Soil quality standards (SQS) are necessary to protect the human health and soil biota from the exposure to soil pollutants. The current SQS in Korea contain only sixteen substances, and it is scheduled to expand the number of substances. Chemical ranking and scoring (CRS) system is very effective to screen the priority chemicals for the future SQS in terms of their toxicity and exposure potential. In this study, several CRS systems were extensively compared to propose the assessment factors that required for the screening of soil pollutants The CRS systems considered in this study include the CHEMS-1 (Chemical Hazard Evaluation for Management Strategies), SCRAM (Scoring and Ranking Assessment Model), EURAM (European Union Risk Ranking Method), ARET (Accelerated Reduction/Elimination of Toxics), CRSKorea, and other systems. The additional assessment factors of CRS suitable for soil pollutants were suggested. We suggest soil adsorption factor as an appropriate factor of CRS system to consider chemical transport from soil to groundwater. Other factors such as soil emission rate and cases of accident of soil pollutants were included. These results were reflected to screen the priority chemicals in Korea, as a part of the project entitled ‘Setting the Priority of Soil Contaminants'.

EU FP6 Welfare Quality® Poultry Assessment Systems

  • Butterworth, A.
    • Korean Journal of Poultry Science
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    • v.36 no.3
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    • pp.239-246
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    • 2009
  • Animal welfare is of considerable importance to European consumers and citizens, this being most recently confirmed in EU barometer studies. Researchers and others have long proposed that animal-based measures (measures taken on animals, e.g. their health and behaviour) can provide a valid indicator of animal welfare; since welfare is a characteristic of the individual animal. Therefore, a welfare assessment can be essentially based on animal-based measures, but with use of resource measures to provide the capacity to assess 'risk factors'. The first goal of this project was to develop a welfare monitoring system that enables assessment of welfare status through standardised conversion of welfare measures into accessible and understandable information. The acquired information on one hand provides feedback to animal unit managers about the welfare status of their animals, and on the other, information on the welfare status of animal-related products for consumers and retailers. The second goal of Welfare $Quality^{(R)}$ was to improve animal welfare by minimising the occurrence of harmful behavioural and physiological states, improving human-animal relationships, and providing animals with safe and stimulating environments. The different measurable aspects of welfare to be covered are turned into welfare criteria. The criteria reflect what is meaningful to animals as understood by animal welfare science. Once all the measures have been performed on an animal unit, a bottom-up approach is followed to produce an overall assessment of animal welfare on that particular unit: first the data collected (i.e. values obtained for the different measures on the animal unit) are combined to calculate criterion-scores; then criterion-scores are combined to calculate principle-scores; and finally the animal unit is assigned to a welfare category according to the principle-scores it obtained.

Development of A Model for Estimating ITS Market Size in Korea (지능형교통체계(ITS)의 시장예측모형 개발에 관한 연구)

  • 배상훈
    • Journal of Korean Society of Transportation
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    • v.19 no.5
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    • pp.21-33
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    • 2001
  • Intelligent Transport Systems (ITS) was first introduced in Korea early 1990's, and Korean government has put a lot of efforts for flourishing it in the entire nation. Regardless of these efforts, private participation is not active enough to accelerate ITS implementation in Korea. Expert group made every endeavor to analyze the current situation, and found out some phenomena. It may be summarized as two folds. Firstly, private sector has a lack of confidence on the future ITS market. Budget in the strategic plan is the only publication and guide that private sector can refer to, and it merely indicates deployment costs. Secondly, direction and procedure of R&D are not well defined. It implies that private sector takes too much risk when they invest for R&D. This research, therefore, focuses on the first issues. Concretely, the goal of the project was to establish and analyze the model for estimation the future ITS market side. Author reviewed both quantitative and qualitative models, and concluded that diffusion model in qualitative model was suitable for ITS market estimation. According to model calibration. it is estimated that 14 trillion Won was the market size in 2020 under normal condition. Impact of this result may seduce Information Technology(IT) related private companies into ITS market. Although this research couldn't cover various topics, it nay dedicate in boosting ITS in Korea. Also, it will be a good starting point for further study for the advancement of ITS.

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Tunnelling in Bangkok - Two Case Studies (방콕의 터널공사 - 두 개의 사례연구)

  • Teparaksa, Wanchai;Cho, Gye-Chun
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.7 no.2
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    • pp.153-163
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    • 2005
  • This paper presents two case studies for tunnelling in Bangkok: a subway tunnel site and a flood diversion tunnel site. The first case study is related to ground displacement response for dual tunnel Bangkok MRT subway. The MRT subway project of Bangkok city consists of dual tunnels about 20 km long with 18 subway stations. The tunnels are seated in the firm first stiff silty clay layer between 15-22 m in depth below ground surface. The behavior of ground deformation response based on instrumentation is presented. The back analysis based on plain strain FEM analysis is also presented and agrees with field performance. The shear strain of FEM analysis is in the range of 0.1-1% and in accordance with the results of self boring pressuremeter tests. Meanwhile, the second case study is related to the EPB tunnelling bored underneath through underground obstruction. The Premprachakorn flood diversion tunnel is the shortcut tunnel to divert the flood water in rainy season into the Choapraya river. The tunnel was bored by means of EPB shield tunnelling in very stiff silty clay layer at about 20-24 m in depth. During flood diversion tunnel bored underneath the existing Bangkok main water supply tunnel and pile foundation of the bridge, instrumentation was monitored and compared with predicted FEM analysis. The prevention risk potential by means of predicting damage assessment is also presented and discussed.

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Soil Pollution and Contaminated Soil Management of the Public Housing Agency in Residential Land Development (전국 토양오염실태 및 공공택지개발지구의 오염토양 관리)

  • Oh, Jeongik;Jin, Kyunam;Lee, Hyunjeong
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.7
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    • pp.377-386
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    • 2016
  • The purposes of this research are to examine soil pollution in the nation and to explore the contaminated soil management of the public housing agency in public land for residential development. In so doing, the primary and secondary data were utilized, the former made use of the public data annually released by the Korea Ministry of Environment, and the latter relied on a self-administerd questionnaire survey conducted in the staff of the public housing agency, particularly those in charge of soil contamination in large-scale land, housing and urban development projects. The findings reveal that the national concentrations of 21 inorganic and organic soil contaminants (e.g., Cd, Cu, As, Hg, Pb, Cr, Zn, Ni, F, P, PCB, CN, Phenol, BTEX, TPH, TCE, PCE, Benzo(a)pyrene, and pH) in the land were extracted to be well below the risk level designated by the statutory guidance while industrial areas had them at a relatively modest level. In addition, the survey results indicate that the public housing agency didn't establish specific and clear guidelines for soil pollution and its remediation in the residential land development, so that contaminated sites have been primarily remediated by outsourcing companies. As the unexpected occurrence of contaminated sites causes the incurring expenses added to total project budget, the provision of both professional training and on-site manuals with the sufficient information on techniques and methods of soil contamination is critical to promptly and systematically deal with soil pollution.