• Title/Summary/Keyword: Profiles

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A Performance Comparison of Protein Profiles for the Prediction of Protein Secondary Structures (단백질 이차 구조 예측을 위한 단백질 프로파일의 성능 비교)

  • Chi, Sang-Mun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.22 no.1
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    • pp.26-32
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    • 2018
  • The protein secondary structures are important information for studying the evolution, structure and function of proteins. Recently, deep learning methods have been actively applied to predict the secondary structure of proteins using only protein sequence information. In these methods, widely used input features are protein profiles transformed from protein sequences. In this paper, to obtain an effective protein profiles, protein profiles were constructed using protein sequence search methods such as PSI-BLAST and HHblits. We adjust the similarity threshold for determining the homologous protein sequence used in constructing the protein profile and the number of iterations of the profile construction using the homologous sequence information. We used the protein profiles as inputs to convolutional neural networks and recurrent neural networks to predict the secondary structures. The protein profile that was created by adding evolutionary information only once was effective.

Study on the Reconstruction of KSTAR Plasma Density Profiles Using Microwave Reflectometry (마이크로파 레플렉토메터리를 이용한 KSIAR 플라즈마 밀도분포 재구성에 관한 연구)

  • Roh Young-Su
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.54 no.8
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    • pp.365-370
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    • 2005
  • Microwave diagnostics have been widely utilized to measure the important parameters of high temperature and high density plasmas. Reflectometry is known as a promising microwave diagnostic which has a number of merits to measure electron density profiles. In the KSTAR device, X-mode FM reflectometry is planned to measure the plasma density profiles. FM reflectometry is required to extract phase information on raw mixer IF signals, thereby obtaining time-of-flight of reflectometry signals. It is known that the data analysis method is crucial to determine the performance of FM reflectometry In fact, there are several analysis programs which have been utilized in various FM systems. Since each program was developed for a specific device, however, it is difficult to directly apply it to a different reactor like the KSTAR device. It is necessary, therefore, to develop a data analysis program for the KSTAR FM reflectometry. In this paper, complex digital demodulation (CDM) and wavelet transformation are examined in terms of the performance of density profile reconstruction. For the comparison of both methods, FM reflectometry signals are generated on the basis of assumed profiles and the interaction of the X-mode wave and the plasma. In order to see how well both methods work under various conditions, three types of profiles are assumed and noise effects are included. As a result, both methods work well under the condition of gentle density gradient and small noise level. As density gradient becomes steeper and noise level gets higher. the reconstruction performance of wavelet is better than that of CDM.

A Transformation Technique of PIM to PSM based on UML Profiles for Mobile Applications (UML 프로파일에 기반한 모바일 어플리케이션의 PIM/PSM 변환 기법)

  • Choi, Yun-Seok
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.6
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    • pp.131-144
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    • 2012
  • MDD is suitable to satisfy constraints of development of mobile applications. So, there are various studies about applying MDD to the developments of mobile application but systematic development methods about UML profile for PIM/PSM of mobile applications and model transformation techniques are needed. This paper suggests that a development technique about UML profile for PIM/PSM of mobile applications and a model transformation techniques with the profiles. We classify stereotypes by the characteristics of mobile application to compose profiles and suggest development guidelines of profiles for PIM/PSM. On the suggested model transformation process, the PIM with the profiles is transformed to the intial PSM with the mapping rules and the PSM is transformed to the refined PSM with templates which reflected detailed information of a mobile platform. We developed a location based service mobile application with the suggested techniques on the Android platform and compared with other techniques to validate usefulness of the suggested techniques.

Characteristics of Anthropogenic Soil Formed from Paddy near the River

  • Sonn, Yeon-Kyu;Zhang, Yong-Seon;Hyun, Byung-Keun;Kim, Keun-Tae;Lee, Chang-Hoon
    • Korean Journal of Soil Science and Fertilizer
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    • v.49 no.5
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    • pp.434-439
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    • 2016
  • Anthropogenic soil in cropland is formed in the process of subsoil reversal and the refill of soil into cropland. However, there was little information on the chemical properties within soil profiles in anthropogenic soil under rice paddy near the river. In this study, we investigated the chemical properties within soil profiles in the anthropogenic soil located at 4 sites in Gumi, Kimhae, Chungju, and Euiseong to compare with the natural paddy soil near the river. Among particle sizes, the sand content decreased under soil profiles but the silt and clay contents increased compared to the natural paddy soil in soil profiles. Organic matter content in topsoil of anthropogenic soil was lower than in that of natural soil, which was shown the contrary tendency within soil profiles. Also, the soil pH, available $P_2O_5$, and exchangeable cations were higher in anthropogenic soil compared to natural paddy soil at topsoil, which was maintained these tendency into soil depth. Nutrients may be equally distributed in anthropogenic soil during the process of refill in paddy soil near the river. This results indicated that anthropogenic soil would contribute to carbon sequestration, the mitigation of compaction, and reduction of fertilizer application in paddy soil. Therefore, characteristics of anthropogenic soil can be used for the soil management in cropland.

Effects of Cesarean Section in Dogs on Blood Coagulation Profiles (개 제왕절개 수술이 혈액응고계에 미치는 영향)

  • Ahn, So-Jeo;Jeoung, Seok-Young;Kwon, Eun-Jung;Park, Son-Il;Kim, Doo
    • Journal of Veterinary Clinics
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    • v.24 no.2
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    • pp.160-163
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    • 2007
  • Patients often present with spontaneous bleeding, or a bleeding disorder may be discovered when an otherwise healthy dog develops marked bleeding during or after surgery. In this study, we were aimed to elucidate whether the cesarean section in dogs has influence on the coagulation profiles. And we gained the normal data on a panel of screening laboratory tests which allow accurate characterization of a hemostatic defects in dogs. Of the 20 healthy adult dogs, buccal mucosa bleeding time (BMBT) was $83.0{\pm}10.5$ seconds, platelet count was $24.0{\pm}3.5{\times}10^4/{\mu}l$, activated partial thromboplastin time (APTT) was $8.8{\pm}2.0$ seconds, the concentration of fibrinogen was $288.5{\pm}77.9mg/dl$, and the concentration of fibrin degradation products (D-dimer) was <250.0 ng/ml. Coagulation profiles before and after cesarean section of 13 cesarean sectioned dogs were in the normal range and there were no statistical differences in coagulation profiles between normal dogs and cesarean sectioned dogs (p>0.05). The results suggested that labor and cesarean section in healthy dogs did not alter coagulation profiles.

The effects of Momordica charantia on obesity and lipid profiles of mice fed a high-fat diet

  • Wang, Jun;Ryu, Ho Kyung
    • Nutrition Research and Practice
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    • v.9 no.5
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    • pp.489-495
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    • 2015
  • BACKGROUND/OBJECTIVES: The present study was conducted to investigate the effects of dried Momordica charantia aqueous extracts (MCA) and ethanol extracts (MCE) on obesity and lipid profiles in mice fed a high-fat diet. MATERIALS/METHODS: Forty two ICR mice were randomly divided into six groups. The normal group was fed a basal diet, and other groups were fed a 45% high-fat diet (HFD) for 7 weeks. The normal and HFD groups were also orally administered distilled water each day for 7 weeks. The remaining groups received Momordica charantia extract (0.5 or 1.0 g/kg/day MCA, and 0.5 or 1.0 g/kg/day MCE). In order to measure the anti-obesity and lipid profile improvement effects, body and visceral tissue weight, lipid profiles, plasma insulin levels, hepatic malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity were measured. RESULTS: Both MCA and MCE significantly decreased body and visceral tissue weight relative to those of the HFD group (P < 0.05). Additionally high doses of MCE and MCA significantly reduced the plasmatic insulin levels compared to the HFD groups (P < 0.05) to concentrations comparable to those found in the normal group. MCA and MCE supplementation also significantly modulated the lipid profiles in plasma, liver, and feces compared to mice fed the HFD (P < 0.05). Furthermore MCA and MCE significantly increased hepatic SOD activity, and reduced MDA generation in the liver of the HFD mice (P < 0.05). CONCLUSIONS: Results from the present study suggest that Momordica charantia extracts have anti-obesity effects and the ability to modulate lipid prolife of mice fed a HFD by suppressing body weight gain, visceral tissue weight, plasma and hepatic lipid concentrations, and lipid peroxidation along with increasing lipid metabolism.

Person-centered Approach to Organizational Commitment: Analyses of Korean Employees' Commitment Profiles (조직몰입에 대한 사람중심 접근: 국내 직장인들의 조직몰입 프로파일 분석)

  • Oh, Hyun-Sung;Jung, Yongsuhk;Kim, Woo-Seok
    • Journal of the Korean Data Analysis Society
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    • v.20 no.6
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    • pp.3049-3067
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    • 2018
  • Although there is a growing body of research on organizational commitment profiles based on a person-centered approach, it is not widely applied to the commitment research conducted by Korean organizational scholars yet. Therefore, in this paper, we introduced the concept and analytical methods, such as cluster analysis and latent profile analysis (LPA), of the person-centered approach. In addition, we also performed both cluster analysis and LPA to identify types of organizational commitment profiles of Korean employees based on the combination of affective, continuance and normative commitment on the sample from a range of different fields in South Korea (n = 349). Both analyses extracted two comparable sets of 6 commitment profiles. These six profiles were then contrasted with employee turnover intention. Finally, implications for commitment theory, practices and future research issues were discussed.

Estimation of Dynamic Material Properties for Fill Dam : I. In-situ Shearwave Velocity Profiles (필댐 제체 재료의 동적 물성치 평가 : I. 현장 전단파 속도 주상도)

  • Kim, Jong-Tae;Kim, Dong-Soo;Park, Heon-Joon;Kwon, Hyek-Kee
    • Journal of the Korean Geotechnical Society
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    • v.25 no.12
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    • pp.69-85
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    • 2009
  • It is very important to measure reliable dynamic properties of each zone in dam for seismic design. However, the Vs values of core and rock-fill zone are seldom determined by field test. Consequently, seismic design in dam is performed using Vs values assumed or empirically determined. So, it is required that reliable Vs has to be evaluated by in-situ test. In this study, surface wave method, which is nondestructive, was applied to dam to evaluate Vs profiles of core and rock-fill zone in dam. In 6 dams, using SASW and HWAW methods, Vs profiles were evaluated reliably. D/B of Vs profiles of each zone with depth and relationship between confining pressure and Vs profiles of rock-fill zone were constructed including existing results of other dams. The evaluated D/B and proposed relationship were compared with the frequently used empirical method by Sawada and Takahashi.

The Effects of Job Demand-control-support Profiles on Presenteeism: Evidence from the Sixth Korean Working Condition Survey

  • Ari Min;Hye Chong Hong
    • Safety and Health at Work
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    • v.14 no.1
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    • pp.85-92
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    • 2023
  • Background: Presenteeism is closely related to work performance, work quality and quantity, and productivity at work. According to the job demand-control-support model, job demand, job control, and support play important roles in presenteeism. The present study investigated job characteristics profiles based on the job demand-control-support model and identify the association between job characteristics profiles and presenteeism. Methods: This secondary data analysis used the Sixth Korean Working Condition Survey, a nationwide cross-sectional dataset. The study included 25,361 Korean wage workers employed in the workplace with two or more workers. Participants were classified into four job characteristics profiles based on the job demand-control-support model, using latent profile analysis, and logistic regression was performed to examine the association between study variables. Results: Overall, 11.0 % of study participants reported experience of presenteeism in the past 12 months. Age, sex, location, monthly income, shift work, work hours, health problems, and sleep disturbances were significantly associated with presenteeism. The rate of presenteeism was the highest in the passive isolate group. The passive collective, active collective, and low-stain collective groups had a 23.0%, 21.0%, and 29.0% lower likelihood of experiencing presenteeism, respectively, than the passive isolate group. Conclusions: The job demand-control-support profiles and the risk of presenteeism were significantly associated. The most significant group that lowered the experience of presenteeism was the low-strain collective group, which had a low level of demand and high levels of control and support. Therefore, we need a policy to reduce job demand and increase job control and support at the organizational and national levels.

Career decision profiles and characteristics of nursing students (간호대학생의 진로결정유형과 유형별 특성)

  • Jung, Young-Mi;Jung, Yeon-I
    • The Journal of Korean Academic Society of Nursing Education
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    • v.30 no.2
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    • pp.160-169
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    • 2024
  • Purpose: This study aimed to identify the career decision profiles for nursing students and analyze their career barriers, preparation behaviors, decision-making self efficacy, and adaptability according to the career decision profiles. Methods: This cross-sectional study used content analysis. A total of 219 nursing students enrolled in two private Korean universities participated in this study. The data were collected in person and via email between December 8 and 31, 2020. Results: The decidedness and comfort results were statistically significant. Four clusters were identified: undecided-uncomfortable, decided-uncomfortable, decided-comfortable, and undecided-comfortable. Most participants were found to be decided-uncomfortable, followed by decided-comfortable, undecided-uncomfortable, and undecided-comfortable. The self efficacy scores were higher for the decision-comfortable profile than for the undecided-uncomfortable and decided-uncomfortable profiles. The mean adaptability scores were higher for the decision-comfortable profile than for the undecided-comfortable profile. Career barriers were negatively correlated with preparation behavior, decision-making self efficacy, and adaptability, while preparative behaviors were positively correlated with decision-making self efficacy and adaptability. Decision-making self efficacy was positively correlated with adaptability. The mean career barriers, preparation behaviors, decision-making self efficacy, and adaptability scores differed significantly across profiles. The mean career barrier score was higher for the undecided-uncomfortable than for the decided-comfortable profile; preparation behaviors exhibited no significant differences. Conclusion: Tailored career coaching and counseling programs based on personal characteristics and areas of interest are needed for freshmen and senior nursing students to reduce career barriers and to improve preparation behaviors, decision-making self efficacy, and adaptability.