Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Effects of Cesarean Section in Dogs on Blood Coagulation Profiles

개 제왕절개 수술이 혈액응고계에 미치는 영향

  • Ahn, So-Jeo (School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Jeoung, Seok-Young (School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Kwon, Eun-Jung (School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Park, Son-Il (School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University) ;
  • Kim, Doo (School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University)
  • 안소저 (강원대학교 수의학부대학 및 동물의학종합연구소) ;
  • 정석영 (강원대학교 수의학부대학 및 동물의학종합연구소) ;
  • 권은정 (강원대학교 수의학부대학 및 동물의학종합연구소) ;
  • 박선일 (강원대학교 수의학부대학 및 동물의학종합연구소) ;
  • 김두 (강원대학교 수의학부대학 및 동물의학종합연구소)
  • Published : 2007.06.30
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Abstract

Patients often present with spontaneous bleeding, or a bleeding disorder may be discovered when an otherwise healthy dog develops marked bleeding during or after surgery. In this study, we were aimed to elucidate whether the cesarean section in dogs has influence on the coagulation profiles. And we gained the normal data on a panel of screening laboratory tests which allow accurate characterization of a hemostatic defects in dogs. Of the 20 healthy adult dogs, buccal mucosa bleeding time (BMBT) was $83.0{\pm}10.5$ seconds, platelet count was $24.0{\pm}3.5{\times}10^4/{\mu}l$, activated partial thromboplastin time (APTT) was $8.8{\pm}2.0$ seconds, the concentration of fibrinogen was $288.5{\pm}77.9mg/dl$, and the concentration of fibrin degradation products (D-dimer) was <250.0 ng/ml. Coagulation profiles before and after cesarean section of 13 cesarean sectioned dogs were in the normal range and there were no statistical differences in coagulation profiles between normal dogs and cesarean sectioned dogs (p>0.05). The results suggested that labor and cesarean section in healthy dogs did not alter coagulation profiles.

Keywords

References

  1. Bang NU. Diagnosis and management of bleeding disorders. In: Textbook of critical care, 2nd ed. Philadelphia: WB Saunders Co. 1989: 869-886
  2. Benjamin MM. Hemostatic disorder. In: Outline of veterinary clinical pathology, 3rd ed. Iowa: The Iowa State University Press. 1978: 162-174
  3. Brooks M, Catalfame J. Buccal mucosal bleeding time is prolonged in canine model of primary hemostatic disorders. Thrombosis and Haemostasis 1993; 70: 777-780
  4. Gunzel-Apel AR, Hayer M, Mischke R, Wirth W, Hoppen HO. Dynamics of haemostasis during the oestrous cycle and pregnancy in bitches. J Reprod PertH Suppl 1997; 51: 185-193
  5. Hargis AM, Feldman BF Evaluation of hemostatic defects secondary to vascular tumors in dogs: 11 cases (1983-1988). J Am Vet Med Assoc 1991; 198: 891-894
  6. Jergens AE, Turrentine MA, Kraus KH, Johnson GS. Buccal mambrane bleeding times of healthy dogs and of dogs in various pathologic states, including thrombocytopenia, uremia, and von Willebrand's disease. Am J Vet Res 1987; 48: 1337-1342
  7. Johnstone lB. Clinical and laboratory diagnosis of bleeding disorders. Vet Clin North Am Small Anim Pract 1988; 18: 21-33 https://doi.org/10.1016/S0195-5616(88)50004-9
  8. Kitoh K, Watoh K, Kitagawa H, Sasaki Y. Blood coagulopathy in dogs with shock induced by injection of heartworm extract. Am J Vet Res 1994; 55: 1542-1547
  9. Littlewood JD. A practical approach to bleeding disorders in the dog. J Small Anim Pract 1986; 27: 397-409 https://doi.org/10.1111/j.1748-5827.1986.tb02154.x
  10. Millar HR, Simpson JG, Stalker AL. An evaluation ofthe heat precipitation method for plasma fibrinogen estimation. J Clin Pathol 1971; 24: 827-830 https://doi.org/10.1136/jcp.24.9.827
  11. Millis DL, Hauptman JG, Richter M. Preoperative and postoperative hemostatic profiles of dogs undergoing ovariohysterectomy. Comell Vet 1992; 82: 465-470
  12. Schalm OW, Smith R, Kaneko JJ. Plasma protein: fibrinogen ratios in disease in the dog and horse. Calif Vet 1970; 24: 19-22
  13. Stokol T, Brooks MB, Erb HN, Mauldin GE. D-dimer concentration in healthy dogs and dogs with disseminated intravascular coagulation. Am J Vet Res 2000; 61: 393-398 https://doi.org/10.2460/ajvr.2000.61.393
  14. Tseng LW, Hughes D, Giger U. Evaluation of a point-care coagulation analyzer for measurement of prothrombin time, activated partial thromboplastin time, and activated clotting time in dogs. Am J Vet Res 2001; 62:1455-1460 https://doi.org/10.2460/ajvr.2001.62.1455
  15. Willard MD, Tvedten H, Tumwald GH. Hemostatic abnormalities. In: Small animal clinical diagnosis by laboratory method, 2nd ed. Philadelphia: WB Saunders Co. 1994: 81-96