• Title/Summary/Keyword: Productivity Improvement

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Doxorubicin Productivity Improvement by the Recombinant Streptomyces peucetius with High-Copy Regulatory Genes Cultured in the Optimized Media Composition

  • PARK, HEE-SEOP;KANG, SEUNG-HOON;PARK, HYUN-JOO;KIM, EUNG-SOO
    • Journal of Microbiology and Biotechnology
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    • v.15 no.1
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    • pp.66-71
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    • 2005
  • Doxorubicin is a clinically important anticancer polyketide compound that is typically produced by Streptomyces peucetius var. caesius. To improve doxorubicin productivity by S. peucetius, a doxorubicin pathway-specific regulatory gene, dnrI, was cloned into a high-copy-number plasmid containing a catechol promoter system. The S. peucetius containing the recombinant plasmid exhibited approximately 9.5-fold higher doxorubicin productivity compared with the wild-type S. peucetius. The doxorubicin productivity by this recombinant S. peucetius strain was further improved through the optimization of culture media composition. Based on the Fractional Factorial Design (FFD), cornstarch, $K_2HPO_4$, and $MgSO_4$ were identified to be the key factors influencing doxorubicin productivity. The Response Surface Method (RSM) results based on 20 independent culture conditions with varying amounts of key factors predicted the highest theoretical doxorubicin productivity of 11.1 mg/l with corn starch of 46.33 g/l, $K_2HPO_4$ of 4.63 g/l, and $MgSO_4$ of 9.26 g/l. The doxorubicin productivity of the recombinant S. peucetius strain with the RSM-based optimized culture condition was experimentally verified to be 11.46 mg/l, which was approximately 30.8-fold higher productivity compared with the wild-type S. peucetius without culture media optimization.

A Study on the Improvement for Productivity of Construction Subcontract (건설 하도급 생산성 개선 방안 연구)

  • Lee Tai Sik;Jung Bo Gun
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.337-340
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    • 2001
  • Construction market structure give to third subcontract from contractor that received bid. A general contractor is subcontract to subcontractor that construct final product. When the subcontractor is related with productivity on the site, a study is lack to subcontractor productivity. The property of construction industry include many subcontractor at one project. If a subcontractor will improve productivity, total productivity would improve on the site. We will understand about subcontractor productivity and suggest about productivity method.

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The Relationship between Carbon Productivity and Economic Performance : An Empirical Analysis (탄소생산성과 경제적 성과의 인과성에 관한 실증연구)

  • Yook, Keun-Hyo
    • Journal of Environmental Policy
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    • v.9 no.3
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    • pp.47-67
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    • 2010
  • Carbon productivity is an efficiency concept, well suited to maximizing product/service(economic) value of firms and minimizing environmental impact($CO_2$ emissions). This study investigates the causal relationship between carbon productivity (eco-efficiency) and financial performance in Korean firms. The result shows that firms improving carbon productivity are able to gain superior financial performance. The analysis also show that changes in financial performance have a positive impact on the improvement of carbon productivity. However this study reports that carbon productivity does not have a long-run impact on financial performance and vice versa. Finally, the results also show that differences exist in the relationship between carbon productivity and financial performance when grouped by industry characteristics.

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A Study of Crane Monitoring System for Container Crane (컨테이너 크레인의 CMS에 관한 연구)

  • 김영호;손정기;정동호;배종일;이권순;이만형
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 1998.10a
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    • pp.145-151
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    • 1998
  • This paper is aimed to handle quick work for all the workers and to improve the productivity by adding more effective content in Crane Monitoring System. This contributing proportion of the increase of port productivity is more increasing concerning not only the port industry, but also all the informations of container crane which is the representative equipment by the rapid increase of the volume of freight of port. The basic of rapid service is the improvement of the productivity, the information of operation as to the productivity of crane for the quick handling within yard and especially the informations of breakdown and to handle breakdown as soon as possible has a greate effect on the increase of productivity.

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An Analytical Study for the Labor Productivity Improvement of Enterprise (기업의 노동생산성 향상을 위한 분석연구)

  • 김종래
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.4 no.4
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    • pp.35-42
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    • 1981
  • This paper grasped the labor productivity actual condition by the standard of per unit working hour and production about the main products of our country's industrial the main materials and could understand the average of our country's labor productivity as compared this with the labor productivity actual condition of Japan. As the point at issue of analitical result. 1. Low a matter of thinking about productivity. 2. Have a lot of difficult problem in an industrial part. 3. Have the point at issue on technical development and accumulation. 4. Have the point at issue on management. As a countermeasure about these. 1. must convert the way of use of industrial policy. 2. must make a housing development and special serialization of a small and medium enterprise. 3. must establish an organic technical development system. 4. must grope the policy of management rationalization.

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Information System Impact on Swine Productivety (양돈농가의 정보시스템 사용 효과 분석)

  • Lee, Min-Soo;Choe, Young-Chan;Kim, Sang-Ho
    • Journal of Agricultural Extension & Community Development
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    • v.17 no.4
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    • pp.933-955
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    • 2010
  • Researchers have different views on impact of information system use on productivity. The differences are fueled by 'the productivity paradox' insisted by Brynjofsson(1993). This paper intend to quantitate impacts of information system and to test the productivity paradox of using the information system. Restricted Maximumlikelihood Estimation(RMLE) method is applied on data from 81 farms adopting Pigplan system. The results find positive productivity improvement with information systems in swine farm. Adopting Pigplan system increases 0.52 in PSY(pigs per sow per year) and 0.087 in sow turnover. When it comes to region and farm size, region has impact on both PSY and sow turnover, while farm size does not. This result infers that local cooperatives, regardless of farm size, differentiate the impacts of the information system, implying that the ability to utilize information systems should be improved in organizational level.

Wind Tunnel Testing Productivity at KARI LSWT

  • Chung, Jindeog;Cho, Taehwan;Sung, Bongzoo;Lee, Jangyeon
    • International Journal of Aeronautical and Space Sciences
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    • v.2 no.1
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    • pp.103-109
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    • 2001
  • Productivity enhancement program of wind tunnel testing has begun at Korea Aerospace Research Institute Low Speed Wind Tunnel (KARI LSWT). A previous test record of a canard airplane model was adopted to examine the current status of wind tunnel testing efficiency. The time consumed to perform testing activities from the model preparation to data collection was broken down and the results were compared with those of the recent Boeing low speed test result. The efforts to improve the wind tunnel productivity consisted of the installation of mini crane underneath of test section, fabricating lift device for image fairings, model configuration changing rigs and the modifications of external balance system. Time reductions for changing strut interface platform and installation of image fairings. These effects showed more than 70% improvement over the previous test time. Integration of the new and modified systems will improve productivity of wind tunnel testing in KARI LSWT.

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A Study for Monitoring Method of Crane (크레인의 모니터링 기법에 관한 연구)

  • 김영호;이영일;박종웅;배종일;김영식
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.206-206
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    • 2000
  • This paper is ai ed to handle quick work for all the workers and to improve the productivity by adding more effective content in Crane Monitoring System. The contributing proportion of the increase of port productivity is more increasing concerning not only the port industry, but also all the informations of container crane which is the representative equipment by the rapid increase of the volume of freight of port. The basic of rapid service is the improvement of the productivity, the information of operation as to the productivity of crane for the quick handling within yard and especially the informations of breakdown and to handle breakdown as soon as possible has a great enect on the increase of productivity.

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An empirical study on the significance of employment criteria in KORAIL (코레일 신규채용기준의 유의성에 관한 연구)

  • Yin, Tae-Myoung;Park, Soo-Myung
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.1914-1923
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    • 2009
  • KORAIL continuously drives practical reforms of change and originality both internally and externally for the purpose of adapting to rapidly changing circumstance and promote productivity of the organization. Various management strategies are needed to increase its productivity, yet the fist thing to be considered is to select talented human resources. A selection of the human resource should be conducted based on 3R(Right People, Right Place, Right Time). This study empirically analyzes through actual study how the method of new employment introduced on January 1, 2005 positively affects capability and productivity of each member of KORAIL. The area of this study is defined centering on the standard of new employment, capability of personnel, and productivity of the organization. Also, the improvement of new employment standard of KORAIL is suggested as significance of the standard was verified through survey of the standard, the capability and the productivity conducted to KORAIL working personnel.

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RMQC Monitoring Method via PLC (PLC를 이용한 RMQC 모니터링 기법)

  • Kim, Y.H.;Jung, D.J.;Bae, J.I.;Lee, D.C.
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.3189-3191
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    • 2000
  • This paper is aimed to handle quick work for all the workers and to improve the productivity by adding more effective content in Crane Monitoring System. The contributing proportion of the increase of port productivity is more increasing concerning not only the port industry, but also all the informations of container crane which is the representative equipment by the rapid increase of the volume of freight of port. The basic of rapid service is the improvement of the productivity, the information of operation as to the productivity of crane for the quick handling within yard and especially the informations of breakdown and to handle breakdown as soon as possible has a great effect on the increase of productivity.

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