• Environmental Engineering Research
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• 제22권1호
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• pp.40-54
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• 2017

According to FAO, "agricultural sectors are particularly exposed to the effects of climate change and increases climate variability". As a result, the study makes an attempt to answer the question: Is there a causal effect between agricultural production and carbon dioxide emissions in Ghana? By employing a time series data spanning from 1960 to 2015 using the Autoregressive Distributed Lag method. There was evidence of a long-run equilibrium relationship running from copra production, corn production, green coffee production, milled rice production, millet production, palm kernel production and sorghum production to carbon dioxide emissions. The short-run equilibrium relationship shows that, a 1% increase in copra and green coffee production will increase carbon dioxide emissions by 0.22% and 0.03%, a 1% increase in millet and sorghum production will decrease carbon dioxide emissions by 0.13% and 0.11% in the short-run while a 31% of future fluctuations in carbon dioxide emissions are due to shocks in corn production. There was bidirectional causality between milled rice production and carbon dioxide emissions, millet production and carbon dioxide emissions and, sorghum production and carbon dioxide emissions; and a unidirectional causality running from corn production to carbon dioxide emissions and carbon dioxide emissions to palm kernel production.

• Asian-Australasian Journal of Animal Sciences
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• 제24권6호
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• pp.825-833
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• 2011

Forty-five Hisex commercial layers and forty-five local Saudi breed layers were used to determine the acceptable limit of short-term water restriction in the late phase of production, when the problem of high feed and water consumption is expected. The experiment was performed under hot and arid environmental conditions when the layers were at fifty weeks of age. Layers from each breed were randomly assigned in groups of five into nine floor pens. The average environmental temperature was 37.2-$38.6^{\circ}C$, and the relative humidity was between 20 to 37%. The trial was divided into 3 periods; control (1 week), water restriction (2 weeks) and rehydration (1 week). During the restriction period, layers from each breed were divided into three groups that received 20, 40, and 0% restriction of drinking water relative to their consumed water during the control period. During the study, feed and water consumption, body weight, changes in body weight, egg production, primary antibody response to SRBC, and rectal temperature were evaluated. Water restriction did not result in any clear effect on feed intake in either breed, however, commercial layers tended to consume less feed compared to the local breed. Body weight declined with water restriction during the first week of restriction in the commercial breed regardless of rate of restriction, but it was delayed until the second week in the local breed. Water restriction of 40% decreased egg production in both breeds but with a delay of 1 week in the local breed. Antibody level to SRBC was not affected by water restriction in the commercial line while it was highly affected in the local breed. A water restriction of 20% is considered to be an acceptable limit under the current experimental conditions without a negative effect on egg production in both breeds and considering the immune status of the local breed. Whereas, 40% restriction had a negative effect on egg production, and varied effects in the other traits in both breeds.

• Asian-Australasian Journal of Animal Sciences
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• 제18권7호
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• pp.990-996
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• 2005

The effect of diets varying in level and source of nitrogen (N) and fermentable organic matter on dynamic characteristics of microbial populations in rumen liquor and their impact on substrate fermentation in vitro was studied. The diets tested were straw alone, straw+concentrate mixture and straw+urea molasses mineral block (UMMB) lick. The same diets were taken as substrates and tested on each inoculum collected from the diets. Diet had no effect on the amino acid (AA) composition of either bacteria or protozoa. Differences among the diets in intake, source of N and OM affected bacterial and protozoal characteristics in the rumen. Upper asymptote of gas production (Y$\alpha$) had a higher correlation with bacterial pool size and production rate than with protozoal pool size and production rate. Among the parameters of the gas production model, Y$\alpha$ and lag time in total gas has showed significant (p<0.01) correlation with bacterial characteristics. Though the rate constant of gas production significantly differed (p<0.01) between diet and type of straw, it was least influenced by the microbial characteristics. The regression coefficient of diet and type of straw for Y$\alpha$ indicated that the effect of diet on Y$\alpha$ was threefold higher than that of the straw. As microbial characteristics showed higher correlation with Y$\alpha$, and diet had more influence on the microbial characteristics, gas production on a straw diet could be used effectively to understand the microbial characteristics.

• 약학회지
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• 제60권1호
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• pp.21-28
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• 2016

Systemic lupus erythematosus (SLE) is characterized by dysregulatory production of proinflammatory cytokines and helper T (Th) cytokine-dependent autoantibody production. This study aims to investigate the protective effect of baicalin on the dysregulatory production of proinflammatory cytokines and Th cytokines in pristane-induced lupus mice. Mice were received i.p. a single injection of 0.5 ml of pristane, and then, later about 3 months, were used as a pristane-induced lupus model. The pristane-induced lupus mice were administrated orally with baicalin 50 mg/kg once in a day for 10 days. Immune cells obtained from the pristane-primed lupus control group (lupus control) and baicalin-treated pristaneprimed lupus mouse group (BAC lupus) were cultured for 24 h or 36 h with/without mitogens. These results demonstrated that LPS-induced production of macrophage and splenic TNF-${\alpha}$ and Con A-induced production of thymic IFN-${\gamma}$ were attenuated in BAC lupus compared to lupus control, while LPS-stimulated production of macrophage IL-10, Con A-stimulated production of splenic IL-10 and, $PGE_2$-reduced production of splenic IFN-${\gamma}$ enhanced. Therefore, these findings suggest that baicalin may protect from autoimmunity and disease activity in lupus via modulatory effect of proinflammatory cytokine overproduction and Th cytokine imbalance.

• 동의생리병리학회지
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• 제18권1호
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• pp.254-259
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• 2004

Jeongshin-tang (JST) is a Korean herbal prescription, which has been successfully applied for the various neuronal diseases. However, it's effect remains unknown in experimental models. To investigate the biological effect of JST in Alzheimer's disease (AD) in vitro model, we analized the production of interleukin (IL)-6 and IL-8, and expression of cyclooxygenase (COX)-2 in IL-1β plus β-amyloid [25-35] fragment (A)-stimulated human astrocytoma cell line U373MG. JST alone had no effect on the cell viability. The production of IL-6 and IL-8 was significantly inhibited by pretreatment with JST (1mg/㎖) on IL-1β plus A-stimulated U373MG cells. Maximal inhibition rate of IL-6 and IL-8 production by JST was about 41.22% (P<0.01) and 34.45% (P<0.05), respectively. The expression level of COX-2 protein was up-regulated by IL-1β plus A but the increased level of COX-2 was inhibited by pretreatment with JST (1 mg/㎖). These data indicate that JST has a regulatory effect on cytokine production and COX-2 expression, which might explain it's beneficial effect in the treatment of AD.

• 대한음성학회지:말소리
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• 제62호
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• pp.51-68
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• 2007

Two experiments were conducted to determine the exact locus of the frequency effect in speech production. Experiment 1 addressed the question as to whether the word frequency effect arise from the stage of lemma selection. A picture-word interference task was performed to test the significance of interactions between the effects of target frequency, distractor frequency and semantic relatedness. There was a significant interaction between the distractor frequency and the semantic relatedness and between the target and the distractor frequency. Experiment 2 examined whether the word frequency effect is attributed to the lexeme level which represent phonological information of words. A methodological logic applied to Experiment 2 was the same as that of Experiment 1. There was no significant interaction between the distractor frequency and the phonological relatedness. These results demonstrate that word frequency has influence on the processes involved in selecting a correct lemma corresponding to an activated lexical concept in speech production.

• Journal of Plant Biology
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• 제32권4호
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• pp.343-350
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• 1989

Calcium promoted ethylene production from mungbean hypocotyl segments incubated in the presence of either auxin or cytokinin (kinetin). Time course studies indicated that the calcium effect on ethylene production had a longer latent period (about 6 h) in combination with kinetin than with auxin. Studies on the effects of agents that are known to interfere with either action or transport (uptake) of calcium on ethylene biosynthesis indicated different patterns between auxin- and kinetin-treated tissues. Auxin-induced ethylene production was inhibited by the calmodulin inhibitor, trifluoperazine (TFP), and this inhibition was overcome by high concentrations of calcium applied, but TFP had no significant effect on kinetin-induced ethylene production regardless of calcium in the medium. The calcium channel blocker, verapamil, inhibited auxin-induced, but had little effect on kinetin-induced, ethylene producton. In vivo activity of "ethylene forming enzyme (EFE)" was found to be substantially promoted by calcium treatment. The enzyme activity was further increased by kinetin when segments were simultaneously treated with calcium, but auxin did not have such an effect.an effect.

• Journal of Plant Biology
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• 제37권4호
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• pp.445-452
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• 1994

Methyl jasmonate(MeJA)가 녹두(Phaseolus radiatus L.) 하배축과 잎에서 에틸렌 생성에 미치는 영향을 조사하였다. 녹두 하배축 조직에서의 에틸렌 생성은 MeJA의 농도에 비례해서 감소했으며 그 억제 효과는 3시간 이후부터 현저하게 나타났다. 1-Aminocyclopropane-1-carboxylic acid (ACC) oxidase의 활성에 대한 MeJA의 억제 효과 역시 3시간 이후부터 나타났으며 ACC synthase의 활성에는 별 효과가 없었다. $450\;\mu\textrm{M}$ MeJA가 포함된 배지에서 배양시킨 녹두 하배축 조직에서 옥신 유발 에틸렌 생성은 대조구에 비하여 현저히 억제되었는데 이러한 옥신 유발 에틸렌 생성에 대한 MeJA의 억제 기작을 알아보기 위하여 ACC synthase의 활성과 ACC oxidase의 활성을 조사하였다. MeJA는 옥신이 처리된 조직내 ACC양과 ACC synthase 활성 및 ACC oxidase의 활성을 감소시켰다. 따라서 옥신 유발 에틸렌 생성에 대한 MeJA의 억제 효과는 MeJA가 ACC synthase의 활성 뿐만 아니라 ACC oxidase의 활성을 감소시킴으로써 나타난다고 볼 수 있다. 하배축과는 반대로 $4.5\;\mu\textrm{M}$로 처리한 잎 조직에서의 에틸렌 생성은 대조구에 비해 약 50% 촉진되었으며 옥신에 의해 유발된 에틸렌 생성량은 MeJA에 의해 증가되었다. 잎에서의 MeJA에 의한 에틸렌의 합성 증가는 ACC oxidase의 활성 증가에 기인하였으며 ACC synthase의 효소활성은 변화가 없어TEk. 따라서 MeJA는 녹두의 서로 다른 조직에서 에틸렌 합성에 대해 서로 상반된 효과를 나타내었다.

• 대한한의학회지
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• 제21권3호
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• pp.20-30
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• 2000

Objective : This experiment was performed in order to study the effect of an aqueous extract of Salviae radix root(SRRAE) on NO production and NOS gene induction from macrophages Methods : To investigate dose-dependent effects of SRRAE for NO release on the $rIFN-{\gamma}-treated$ macrophages, the cells were incubated for 6 hrs in a medium containing $rIFN-{\gamma}$ (5 U/ml), stimulated with SRRAE and incubated in a CO2 incubator. The cells were treated with 5 U/ml $rIFN-{\gamma}$ plus 100 g/ml of SRRAE, Then, the cells were incubated with various concentrations of NGMMA at $37^{\circ}C$ for 48 hrs, Results : SRRAE had no effect on NO production by itself, whereas recombinant $interferon-{\gamma}(rIFN-{\gamma})$ alone showed modest activity, When SRRAE was used in combination with $rIFN-{\gamma}$, there was a marked cooperative induction of NO production in a dose-dependent manner. The optimal effect of SRRAE on NO production was shown at 6hrs after treatment with $rIFN-{\gamma}$. The SRRAE-induced production of NO was inhibited by NG-monomethyl- L-arginine(NGMMA) and arginase. $rIFN-{\gamma}$ in combination with SRRAE showed a marked increase of the expression of the inducible NOS(iNOS) gene. In addition, the effect of SRRAE was mainly dependent on the SRRAE-induced tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ secretion. Conclusions : SRRAE induces NO production from macrophages as a result of SRRAE-induced $TNF-{\alpha}$ secretion. SRRAE may provide a second signal for synergistic induction of NO production in macrophages already induced to express iNOS gene by $rIFN-{\gamma}$.

• Asian-Australasian Journal of Animal Sciences
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• 제12권4호
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• pp.590-596
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• 1999

The effect of evaporative cooling in alleviating seasonal variations of dairy cows raised in AlMarai Dairy Farms in the Kingdom of Saudi Arabia were studied using milking record collected during the period of 1991 to 1996. The data included 13303 and 8137 records represented winter and summer calving seasons. Evaporative cooling system improved production for cows calved in summer. The least square means of milk yield were 9631 and 9556 liter for cows calved in winter and summer seasons but no significant differences (p<0.05) were observed between the yield of two seasons. No significant effect of season on calving under evaporative cooling on most of the biweekly points of the lactation curve. The farm, parity and milk level showed a significant effect on the shape of the curve. Functions of the lactation curve like initial yield, 305 MY, peak yield, time of peak and duration were estimated for each phase of the lactation curve.