• 대한영양사협회학술지
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• 제19권3호
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• pp.236-252
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• 2013

The purpose of this study was to assess the microbiological quality of home-delivered meals during production and delivery for children from low-income families. Production flows from a facility in Seoul that provides home-delivered meals were analyzed and the time-temperature of the food was measured. Microbiological assessment was performed for the production environment, personal hygiene, and food samples at each production and delivery step based on the process approach. It took 2 hours or longer from completion of production to meal delivery. An aerobic colony count (ACC) and coliform were not detected at knives, cutting boards, and dish towels. However, ACC (at pre-preparation, preparation, and packing areas) and coliform (at the preparation area) were detected on the hands and gloves of employees. Air-borne bacterial counts varied according to day and preparation area (ND~6 CFU/plate/15 min). Food temperatures, on the completion of production and meal delivery, fell into temperature danger zones. ACC and coliform counts of raw ingredients did not decrease after pre-preparation (washing and sanitizing) for menus involving food preparation with no cook step. ACC decreased after cooking step for menus of food preparation with cook step, but the ACC of the stir-fried and seasoned dried filefish fillet on the completion of cooking was too numerous to count due to improper heating. The ACC of seasoned young Chinese cabbages (a menu with complex food preparation) increased during delivery (from 2.5 log CFU/ml to 5.0 log CFU/ml). This qualitative assessment of foodborne pathogens revealed that B. cereus was detected in vegetable and meat product menus. These results suggest time-temperature control is necessary during production and delivery and management guidelines during production of home-delivered meals are provided for safe production.

• 말소리와 음성과학
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• 제9권4호
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• pp.1-7
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• 2017

It was shown in speech production studies that the preparation unit of spoken word production is language particular, such as onset phonemes for English and Dutch, syllables for Mandarin Chinese, and morae for Japanese. However, there have been inconsistent results on whether the onset phoneme is a planning unit of spoken word production in Korean. In this study, two sets of experiments investigated possible influences of task demands on the phonological preparation in native Korean adults, namely, implicit priming and word naming with the form preparation paradigm. Only the word naming task, but not the implicit priming task, showed a significant onset priming effect, even though there were significant syllable priming effects in both tasks. Following the attentional theory ($O^{\prime}S{\acute{e}}aghdha$ & Frazer, 2014), these results suggest that task demands might play a role in the absence/presence of onset priming effects in Korean. Native Korean speakers could maintain their attention to the shared onset phonemes in word naming, which is not very demanding, while they have difficulties in allocating their attention to such units in a more cognitive-demanding implicit priming, even though both tasks involve accessing phonological codes. These findings demonstrate that there are cross-linguistic differences in the first selectable unit in preparation of spoken word production, but within a single language, the preparation unit might not be immutable.

• 한국직업건강간호학회지
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• 제19권2호
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• pp.117-127
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• 2010

Purpose: The purpose of this study was to investigate the factors that influenced the preparation for later life of the age group of 30s, 40s, and 50s in production workers. Methods: The participants for this study were 320 men working in 2 workspaces of Ulsan city. The data was collected from May to July, 2010 using structured questionnaires. Chi-square, One way ANOVA, Duncan test, Pearson's Correlation Coefficient and multiple regression with the SPSS WIN 17.0 program were used to analyze the data. Results: There were statistically significant differences among 30s, 40s, and 50s workers regarding the preparation for later life, health promoting behavior, knowledge and attitude of cerebrocardiovascular (CVD) diseases. 50s workers were significantly more higher than 30s and 40s regarding the preparation for later life, health promoting behavior, cognition and attitude of CVD diseases. The model including variables related to the preparation for later life explained variance of 42.3% of 30s, 36.0% of 40s, and 28.5% of 50s workers. Finally, cognition of CVD diseases and social support were predictors in explaining the level of the preparation for later life among production workers. Conclusion: Based on the findings of the study, nursing interventions should be developed to improve the preparation for later life of production workers according to age differences.

• Asian-Australasian Journal of Animal Sciences
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• 제2권3호
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• pp.413-415
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• 1989

• 대한한의학방제학회지
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• 제14권1호
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• pp.30-41
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• 2006

Recently. the herbal industry has expanded into the herbal dietary supplements industry, the herbal cosmetics industry, etc. But still the main form of herbal drug usage is water extraction- packaging after herb preparation in private clinics. There was no report or data of investigations about industrial herbal preparations. To search for a better plan of herbal drug improvement and popularization. we surveyed the present state of Korean herbal preparation production. We made an industrial herbal preparation list, investigated the total amount of production, the chief items of manufacture. names of prescriptions each item is based on. scales of each production company, etc., and report on them on this article.

• Industrial Engineering and Management Systems
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• 제8권2호
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• pp.109-120
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• 2009

As the use of 3DCAD data became widespread in designing products in manufacturing, attempts have been made to shorten lead time and reduce cost of production preparation utilizing 3DCAD data for launching assembly lines. In order to create assembly plans not only efficient but easy for operators to operate ('easy-to-operate'), this study presents approaches, methods, and systems for creating 3DCGAs (3 Dimensional Computer Graphic Animations) which automatically utilize a prototype-free production preparation methodology. Characteristics of this study include that it proposes the methodology for creating assembly operation 3DCGAs automatically, for all the possible assembly operations corresponding each of the possible assembly sequences first. Using the created 3DCGAs, the study next considers assembly methods by evaluating how easy or 'operator friendly' they are in implementing, and devises tools or jigs to be used, and plans efficient assembly line organization. The concept of the methodology was formed by focusing on the value-adding assembly steps at which parts turn into products directly. The study also validates the effectiveness of the presented methodology by employing the methods used in actual production preparation process in businesses, and proves that an efficient assembly line can be organized in a shorter period of time utilizing the developed system and by preparing easy-to-operate and efficient plans in 3DCGAs at the design stage.

• 경영과학
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• 제4권
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• pp.54-59
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• 1987

FMS is recognized as a useful approach to meet with multi-product small-lot-sized production system Large-scaled investment is needed for installing FMS ; full-discussed systematic prefeasibility analysis and preparation study are necessary for successful installation and running the system. Standardization study is one area of the preparation processes ; especially, standardized production strategy is the core in this area. Conceptual framework and case analysis for the standardization process in relation to FMS installation are suggested in this paper. Case analysis is focused in machinary industry.

• 디지털융복합연구
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• 제19권9호
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• pp.241-255
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• 2021

본 연구는 핵심어 카드 제작 및 수업시연 온라인 평생교육프로그램이 시간제 발달장애 근로자의 직장출근준비기술에 미치는 효과를 검증하는 데에 목적을 두어 실시되었다. 연구 대상은 시간제로 식당사업체에 근무하고 있는 세명의 발달장애 근로자들이며, 이들이 거주하는 가정과 지하철역을 실험 환경으로 구성하였다. 연구 방법은 단일대상연구를 사용하였으며, 이에 따라 기초선, 중재, 유지를 실험의 설계 조건으로 반영하였다. 연구 결과, 연구 대상들은 핵심어 카드 제작 및 수업시연 온라인 평생교육프로그램을 통하여 직장출근준비기술을 효과적으로 습득 및 유지한 것으로 나타났다. 연구 결과를 통해, 본 연구는 구성된 독립변인과 종속변인이 상호간에 갖는 유의미한 기능적 관계가 타당하다는 측면을 논의 및 결론지을 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제26권3호
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• pp.145-155
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• 2022

Multidrug resistance of tumors has been a severe obstacle to the success of cancer chemotherapy. The study wants to investigate the reversal effects of imperatorin (IMP) on doxorubicin (DOX) resistance in K562/DOX leukemia cells, A2780/Taxol cells and in NOD/SCID mice, to explore the possible molecular mechanisms. K562/DOX and A2780/Taxol cells were treated with various concentrations of DOX and Taol with or without different concentrations of IMP, respectively. K562/DOX xenograft model was used to assess anti-tumor effect of IMP combined with DOX. MTT assay, Rhodamine 123 efflux assay, RT-PCR, and Western blot analysis were determined in vivo and in vitro. Results showed that IMP significantly enhanced the cytotoxicity of DOX and Taxol toward corresponding resistance cells. In vivo results illustrated both the tumor volume and tumor weight were significantly decreased after 2-week treatment with IMP combined with DOX compared to the DOX alone group. Western blotting and RT-PCR analyses indicated that IMP downregulated the expression of P-gp in K562/DOX xenograft tumors in NOD/SCID mice. We also evaluated glycolysis and glutamine metabolism in K562/DOX cells by measuring glucose consumption and lactate production. The results revealed that IMP could significantly reduce the glucose consumption and lactate production of K562/DOX cells. Furthermore, IMP could also remarkably repress the glutamine consumption, α-KG and ATP production of K562/DOX cells. Thus, IMP may sensitize K562/DOX cells to DOX and enhance the antitumor effect of DOX in K562/DOX xenograft tumors in NOD/SCID mice. IMP may be an adjuvant therapy to mitigate the multidrug resistance in leukemia chemotherapy.

• 산업공학
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• 제14권2호
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• pp.120-126
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• 2001

Virtual manufacturing is a technology facilitating effective development and agile manufacturing of products via sophisticated computer models representing physical and logical schema and behavior of real manufacturing systems including manufacturing resources, environments, and products. Based on these models, virtual manufacturing supports decision making and error checking in the entire manufacturing processes from design to mass production. At first, we analyzed manufacturing preparation activities of the four major production shops such as press, body assembly, painting and final assembly, of a Korean automotive company. We then developed the workflow models out of the analysis by the IDEF methodology, and generated a strategic plan for the systematic application of the virtual manufacturing technologies. We identified many manufacturing preparation activities that can be improved by the application of virtual manufacturing technologies. Finally, we estimated the effect of improvement including time savings in car development processes and corresponding cost savings.