• Journal of the Korean Society of Food Science and Nutrition
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• v.27 no.2
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• pp.333-337
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• 1998

This study was carried out to get infomation on the nitric oxide production ability and its formation mechanisms of polysaccharides extracted from Ganoderma lucidum(PSG) by using murine macrophage cell line. The cultured mycelial cells of Ganoderma lucidum were extracted by alkali, and than neutralized by acid. The extract were passed through the column of DEAE cellulose for more purification. The neutral fraction was concentrated and precipitated with 95% ethanol. The precipitate was lyophilized and PSG was obtained. The immunomodulating effects of PSG on macrophage were performed by using murine macrophage cell line ATCC TIB 71 cells with PSG 0.5mg. PSG alone could not induce the production of nitrite, but it had a significant potential effect on nitrite secretion when the cells were primed and triggered with BCG and Interferon(IFN)-${\gamma}$. Also it was prominent by using calcium channel blocker(verapamil) and adenylate cyclase activator(forskolin).

• IE interfaces
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• v.12 no.1
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• pp.121-131
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• 1999

In this article, a simulation model of a microwave oven assembly line is developed to identify system parameters to improve the system performances such as work-in-process inventories, production lead time, mean earliness, mean tardiness and in-time completion rate. System parameters investigated include dispatching rules, lot sizing, setup time reduction, demand increase, productivity improvement, production scheduling, hardware characteristics, etc. The model has been developed using SIMAN simulation language which has been demonstrated to be a powerful tool to simulate complex manufacturing systems. We have suggested the results obtained to improve the system performances of an existing production line.

• Proceedings of the Safety Management and Science Conference
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• 2007.11a
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• pp.9-19
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• 2007

This study deals with the improvement of production process on a flow production system with the consideration of six sigma. We analyze the production process and survey the important factors of improvement of productivity. Using a six sigma, we find strategic point and suggest a reformation of production process. We applied a simulation technique to simulate the production line proposed by the result of the Six sigma. With the result of the simulation, this study analyzes the propriety of production line and proposes the alternatives of new production process.

• Journal of Industrial Technology
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• v.27 no.A
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• pp.61-67
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• 2007

The construction machine is the composite machine assembled by about 30,000 parts. Excavator, one kind of a construction machine, plays the leading role for export of construction equipment. It is generally impossible to produce all of the items within one company. Especially the supply of hydraulic control valves, one of the core part of the construction equipment, depends on the import heavily. So it is important to make an efficient production plan of hydraulic control valves in the company. The most important thing for the production scheduling of a hydraulic control valve is to make production schedule keeping the start date for assembly line for an excavator and to make minimization of the stock level. The production plan of hydraulic control valve includes the decision of the quantity supplied by subcontractor. This paper presents a scheme for a scheduling system of the hydraulic control valve considering the schedule of the assembly line for excavator production. This paper provides a methodology, which can make a plan of supply and production and generate a detailed schedule for daily production.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.1278-1279
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• 2006

New product line with additional secondary operation of oil pump rotor was built in necessity of increasing capacity. This new line includes steam treatment process after sizing. The new line achieved 1.6 times higher performance compared with a conventional line.

• IE interfaces
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• v.12 no.3
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• pp.437-447
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• 1999

Modeling and system development for the fabrication process in the semiconductor manufacturing is presented in this paper. Maximization of wafer production can be achieved by the wafer flow balance under high utilization of bottleneck machines. Relatively simpler model is developed for the fabrication line by considering main characteristics of logistics. Simulation system is developed to evaluate the line performance such as balance rate, utilization, WIP amount and wafer production. Scheduling rules and input rules are suggested, and tested on the simulation system. We have shown that there exists good combination of scheduling and input rules.

• Korean Journal of Medicinal Crop Science
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• v.12 no.5
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• pp.372-377
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• 2004

Scopolia parviflora Nakai, a rare and endangered species, is the sole plant producing tropane alkaloids (TA) among the Korean native species. In order to enhance TA productivity the SP72 root line was selected by screening 100 of root line, and the optimal culture media for root growth and TA production were investigated with the SP72 roots. Based on the several media, SH and 2B5 medium were determined as growth medium and White and NN medium as production medium. Among the four combinations of two-stage culture, 2BN (2B5 as growth medium plus NN as production medium) showed more enhanced root growth and TA production as compared with production media of White and NN medium and growth media of SH and 2B5 medium, respectively. However, bubble column bioreactor (BCB) cultures applying two-stage culture did not reveal the effective results despite of the each successful operation of two-stage culture in conical flasks and BCB cultures.

• The International Journal of Costume Culture
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• v.2 no.2
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• pp.71-79
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• 1999

The purposes of this study were to 1) identify types and usage levels of production 2) classify apparel manufacturers based on production systems and 3) investigate relationship between characteristics of apparel manufacturers and production system. Apparel manufacturer's characteristics included product line and the number of employees. For this study, the questionnaires were administered to 215 apparel manufacturers in metropolitan area from Feb. to Mar. 1998. Employing a sample of 201, data were analyzed by using factor analysis, descriptive statistics, cluster analysis, discriminant analysis, and multivariate analysis of variance(MANOVA). The following are the results or this study : 1. The production system was identified as three types of production system such as the management centered system, the product centered system and the worker centered system. 2. Based on the three types of the production system, apparel manufacturer were classified into manager centered and product centered groups. 3. With respect to product line, men's wear manufactures were operated the most frequently by manager centered and product centered groups. 3. With respect to product line, men's wear manufacturers were operated the most frequently by management centered system and women's wear manufacturers were operated the most frequently by worker centered system. With respect to the number of employees, apparel manufacturers comprising 5∼19 employees were performed the least frequently worker centered system, while those comprising 50∼99 and 100∼299 employees the least frequently worker centered system.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.14 no.23
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• pp.47-55
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• 1991

In automated assembly line, an automatic guided vehicle system(AGVS) represents a mire versatile means of moving materials automatically. In this paper, the vehicles not only provide the transportation medium between workstations but also as mobile workstations. The objective for the developed model is the determination of the appropriate time to control AGV based assembly line in order to minimize production makespan while maximizing the efficient use of vehicles. In this paper, we consider the finished goods of two types which are produced in assembly line. The assembly line is considered with and without queue. Because no buffer are present in case 1. this model seeks to determine the point in time at which vehicles should be launched in the assembly line without experiencing a delay. The case 2 model also seek to determine the vehicle launch times while minimizing production makespan. The assumption in this model is that the maximum queue size cannot exceed 1 at any time.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.6
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• pp.602-608
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• 2014

Mixed-model production lines are often used in manufacturing systems. In production lines, different product types are simultaneously manufactured by processing small batches. This paper describes a new welding assembly technology involving the development of experimental models for a mixed-model production line in an automobile company. Due to the extensive number of models, the design of a welding assembly system is complicated. Performance evaluation is an important phase in the design of welding assembly lines in a mixed-model production environment. In this study, a new welding assembly technology for a mixed-model production method was used to weld the package tray and dash panel of a vehicle.