• BMB Reports
• /
• v.29 no.6
• /
• pp.489-492
• /
• 1996

A number of anticancer-chemotherapeutic agents induce cell death through the process of apoptosis. Effects of echinomycin, an anticancer agent on cancer progression, were investigated in P388 murine leukemia cells. First, according to the results of cytotoxicity measurement. $IC_{50}$ of echinomycin was 1.12 nM, a relatively lower value than the other examined anticancer agents, mitomycin-C and etoposide Second, the DNA fragmentation assay for echinomycin-treated cells exhibited that echinomycin was able to induce apoptosis in a shorter period of time and with a lower dose than mitomycin-C or etoposide. The data of DNA fragmentation were quite comparable to those of cytotoxicity measurement. Finally we showed that mitogen-activated protein (MAP) kinase, a key protein in cell mitosis, was translocated into the nucleus from the cytosol after treatment with echinomycin. These findings suggest that a MAP kinase-related process may be involved in apoptosis induced by echinomycin.

• Advances in materials Research
• /
• v.13 no.3
• /
• pp.195-202
• /
• 2024

Aluminum alloy is a material that is frequently used in the aerospace and transportation industries due to its high mechanical and corrosion resistance qualities. Unfortunately, aluminum alloys are prone to corrosion, limiting their application in some harsh situations such as when submerged in aqueous environments. The purpose of this study is to investigate how anodizing can increase the corrosion resistance of 6061 Aluminum alloy. The anodizing process was carried out using two different parameters which are voltage (5V, 10V, 15V) and electrolyte sulfuric acid (H₂SO₄) concentration (0.3M, 0.5M) for 1 hour. The anodized samples were performed using several analyses such as X-ray diffraction (XRD) analysis, morphology analysis, and corrosion test. From this study, it is found that the difference in anodizing parameters affects the corrosion resistance of the samples. Sample anodized at 15V, 0.5M gives the best corrosion resistance.

• Journal of the Korean association of regional geographers
• /
• v.21 no.1
• /
• pp.153-175
• /
• 2015

This study is to analyse Korean map inserted in the "Gwandong Gwanseo-jido(關東 關西地圖)" which is reserved in the Gyujanggak Archives as the mother edition of Korean Map("朝鮮圖") in Kangxi Atlas made in Qing dynasty. Map in Gyujanggak is very similar to the Korean map in the Kangxi atlas in terms of shape of southern part of Korean peninsula, boundary of provinces. Especially over 80% of place names on two maps are coincident and over 90% of islands names are identical. It is revealed that map in the Gyujanggak Archive is the most similar map to the Kangxi Atlas in Korea. This map was produced in 1729~1736 which is late compared to the Kangxi Atlas. This difference of production period shows that mother editon of map in Gyujanggak is the base map of Korean Map in Kangxi atlas. The similarity and differences between those maps show the process of edition of geography in the produce the Kangxi atlas. And map in Gyujanggak shows that production of new type of Korean whole map was began in the late $17^{th}$ century.

• Korean Chemical Engineering Research
• /
• v.58 no.3
• /
• pp.408-415
• /
• 2020

In this study, the AE-SOM method, which combines auto-encoder and self-organizing map, is used to detect and diagnose faults in EVA production process. Then, the fault propagation pathways are identified using Granger causality test. One year and seven months of operation data were obtained to detect faults of the process, and the process variables of the autoclave reactor are mainly analyzed. In the data pretreatment process, the data are standardized and 200 samples of each grade are randomly chosen to obtain a fault detection model. After that, the best matching unit (BMU) of each grade is confirmed by applying AE-SOM. The faults are determined based on each BMU. When a fault is found, the most causative variable of the fault is identified by using a contribution plot, and the fault propagation pathway is identified by Granger causality test. The prognostic of the two shutdowns is detected, and the fault propagation pathway caused by the faulty variable was analyzed.

• Journal of Industrial Technology
• /
• v.25 no.B
• /
• pp.47-54
• /
• 2005

The goal of this study is to generate a landslide potential map using GIS(Geographic Information System) based method. A simple and efficient algorithm is proposed to generate a landslide potentialities map from DEM(Digital Elevation Model) and existing maps. The categories of controlling factors for landslides, aspect of slope, soil, vegetation are defined. The weight value for landslide potentialities is calculated from AHP(Analytic Hierarchy Process) method. Slope and Slope-direction is extracted from DEM, and soil information is extracted from digital soil map. Also, vegetation information is extracted from digital vegetation map. Finally, as overlaying, landslide potentialities map is made out, and it is compared with landslide place.

• Proceedings of the Korean Society for Bioinformatics Conference
• /
• 2005.09a
• /
• pp.124-129
• /
• 2005

The Growing Self-Organizing Map (GSOM), an extended type of the Self-Organizing Map, is a widely accepted tool for clustering high dimensional data. It is also suitable for the clustering of short DNA sequences of phylogenetic genomes by their oligonucleotide frequency. The GSOM presents the result of the clustering process visually on a coloured map, where the clusters can be identified by the user. This paper describes a proposal for automatic cluster detection on this map without any participation by the user. It has been applied with good success on 20 different data sets for the purpose of species separation.

• 제어로봇시스템학회:학술대회논문집
• /
• 1996.10b
• /
• pp.1132-1135
• /
• 1996

The objective of this paper is to make a model-based map for the localization of an autonomous mobile robot(AMR) from ultrasonic sensor measurements, that are acquired when the AMR explores unknown indoors. First, the AMR navigates on unknown space by wall-following and gathers range data from the ultrasonic sensor. Then, the range data are converted to a wall-marked gird map, from which lines representing the walls are extracted using the Hough transform. This process is implemented on an AMR having an ultrasonic sensor, and a preliminary experimental result is presented.

• 제어로봇시스템학회:학술대회논문집
• /
• 1991.10a
• /
• pp.342-346
• /
• 1991

산업공정현장에서는 독립적으로 운영되고 있는 프로그램식 단위제어기기들에 대한 연계운영을 위하여 실시간 처리 소규모 네트워크가 도입되어 구축운영되고 있다. 특히 제조생산공정에서는 계층화된 분산 구조로서 공정정보처리를 위하여 공장환경에 적절한 네트워크 구축을 MAP등의 표준화된 규격에 의하여 권고되고 구현되어 운영되고 있다. 본 논문에서는 공장 환경에서의 표준규격으로 제안된 Mini MAP을 기준으로 하여 물리 및 데이타 링크계층을 Petrinet 기법을 활용하여 실시간 처리를 위한 개선된 모델을 제안하고 네트워크의 성능측정 및 시뮬레이션을 수행하였다. 또한 이 모델에 의하여 토큰버스 네트워크를 구성하여 전송 서비스시간과 메세지 처리율을 분석하고 Mini MAP 규격과 함께 성능을 해석하였다.

• Proceedings of the KSRS Conference
• /
• 1998.09a
• /
• pp.331-341
• /
• 1998

With high resolution capability, satellite images are expanding their roles from earth resource monitorings to map production. Until now, maps are produced from airborne photos, but as large as at 1:2,400 scale, low cost satellite ortho images will replace the airborne photos. However, there has been no standard for map productions with satellite images. In this paper, we study the process of map productions with the satellite images of SPOT, IRS-lC, KOMPSAT, the positional accuracy of map features extracted from the satellite images, and the relationship between the image resolution and the map scale.

• Journal of the Korean Society of Earth Science Education
• /
• v.6 no.2
• /
• pp.93-100
• /
• 2013

The purpose of this study is to examine the effect of science related attitudes and science inquiry skill that apply concept maps for 'Ocean' units in middle school science. The subjects of this study consist of four classes third grade middle school students of the Busan Metropolitan City, which were divided into two groups: one is the experimental group which applied concept map teaching and the other is the ordinary teaching group. The result of this study were shown as follow: First, the use of concept map teaching improved the active meaningful process and improved student's science related attitudes in the experimental group. Second, the science lesson using concept map is effective for science inquiry skill in the experimental group. Third, the using concept map teaching created a positive reaction to make the formulation of ideas.