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Histomorphometry and stability analysis of early loaded implants with two different surface conditions in beagle dogs

  • Kim, Dong-Seok;Kim, Dae-Gon;Park, Chan-Jin;Cho, Lee-Ra
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.10-18
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    • 2009
  • STATEMENT OF PROBLEM. Despite an improved bone reactions of Mg-incorporated implants in the animals, little yet has been carried out by the experimental investigations in functional loading conditions. PURPOSE. This study investigated the clinical and histologic parameters of osseointegrated Mg-incorporated implants in early loading conditions. MATERIAL AND METHODS. A total of 36 solid screw implants(diameter 3.75 mm, length 10 mm) were placed in the mandibles of 6 beagle dogs. Test groups included 18 Mg-incorporated implants. Turned titanium implants served as control. Gold crowns were inserted 4 weeks after implant placement and the dogs were immediately put on a food diet. Implants were observed for 10 weeks after loading. Radiographic assessments and stability tests were performed at the time of fixture installation, $2^{nd}$ stage surgery, 4 weeks after loading, and 10 weeks after loading. Histological observations and morphometrical measurements were also performed. RESULTS. Of 36 implants, 33 displayed no discernible mobility, corresponding to successful clinical function. There was no statistically significant difference between test implants and controls in marginal bone levels(P=.46) and RFA values. The mean BIC % in the Mg-implants was $54.5{\pm}8.4%$. The mean BIC % in the turned implant was $45.3{\pm}12.2%$. These differences between the Mg-implant and control implant were statistically significant(P=.005). CONCLUSIONS. The anodized, Mg-incorporated implant demonstrated significantly more bone-to-implant contact(BIC) in early loading conditions. CLINICAL IMPLICATIONS. The results of this study in beagle dogs suggest the possibility of achieving predictable stability of early loaded free-standing dental implants with Mg-incorporated surface.

Evaluation of TMJ sound on the subject with TMJ disorder by Joint Vibration Analysis

  • Hwang, In-Taek;Jung, Da-Un;Lee, Jae-Hoon;Kang, Dong-Wan
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.26-30
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    • 2009
  • STATEMENT OF PROBLEM. Qualitative and semi-quantitative methods have been developed for TMJ sound classification, but the criteria presented are completely inhomogeneous. Thus, to develop more objective criteria for defining TMJ sounds, electroacoustical systems have been developed. We used Joint vibration analysis in the BioPAK system(Bioresearch Inc., Milwaukee, USA) as the electrovibratography. PURPOSE. The aim of this study was to examine the TMJ sounds with repect to frequency spectra patterns and the integral > 300 Hz /< 300 Hz ratios via six-months follow-up. MATERIAL AND METHODS. This study was done before and after the six-months recordings with 20 dental school students showed anterior disk displacement with reduction. Joint vibrations were analyzed using a mathematical technique known as the Fast Fourier Transform. RESULTS. In this study Group I and Group II showed varied integral > 300 /< 300 ratios before and after the six-months recordings. Also, by the comparative study between the integral > 300 /< 300 ratios and the frequency spectrums, it was conceivable that the frequency spectrums showed similar patterns at the same location that the joint sound occurred before and after the six-months recordings. while the frequency spectrums showed varied patterns at the different locations that the joint sound occurred before and after six-month recordings, it would possibly be due to the differences in the degree of internal derangement and/or in the shape of the disc. CONCLUSIONS. It is suggested that clinicians consider the integral > 300 /< 300 ratios as well as the frequency spectrums to decide the starting-point of the treatment for TMJ sounds.

The change of rotational freedom following different insertion torques in three implant systems with implant driver

  • Kwon, Joo-Hyun;Han, Chong-Hyun;Kim, Sun-Jai;Chang, Jae-Seung
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.37-40
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    • 2009
  • STATEMENT OF PROBLEM. Implant drivers are getting popular in clinical dentistry. Unlike to implant systems with external hex connection, implant drivers directly engage the implant/abutment interface. The deformation of the implant/abutment interface can be introduced while placing an implant with its implant driver in clinical situations. PURPOSE. This study evaluated the change of rotational freedom between an implant and its abutment after application of different insertion torques. MATERIAL AND METHODS. Three kinds of internal connection implants were utilized for the current study($4.5{\times}12\;mm$ Xive, $4.3{\times}11.5\;mm$ Inplant Magicgrip, $4.3{\times}12\;mm$ Implantium MF). An EstheticBase, a 2-piece top, a Dual abutment was used for its corresponding implant system. The rotational freedom between an implant and its abutment were measured before and after applying 45, 100 Ncm insertion torque. Repeated measures ANOVA was used for statistical analysis. RESULTS. Under 45 Ncm insertion torque, the rotational freedom between an implant and its abutment was significantly increased in Xive(P = .003). However, no significant change was noted in Inplant Magicgrip and Implantium MF. Under 100 Ncm torque, both in Xive(P = .0005) and Implatium MF(P = .03) resulted in significantly increased rotational freedom between the implant and its abutment. DISCUSSION. The design of the implant/implant driver interface effectively prevented the deformation of implant/abutment interface. Little change was noted in the rotational freedom between an implant and its abutment, even though the insertion torque was far beyond clinical application. CONCLUSIONS. The implant/abutment joint of internally connecting implants were quite stable under insertion torque in clinical situation.

Effect of adhesive primers on bonding strength of heat cure denture base resin to cast titanium and cobalt-chromium alloy

  • Kim, Su-Sung;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Lim, Hyun-Pil
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.41-46
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    • 2009
  • STATEMENT OF PROBLEM. The poor chemical bonding of a denture base resin to cast titanium framework often introduces adhesive failure and increases microleakage. PURPOSE. This study evaluated the shear bond strengths of a heat cure denture base resin to commercially pure titanium, Ti-6Al-4V alloy and a cobalt-chromium alloy using two adhesive primers. MATERIAL AND MATHODS. Disks of commercially pure titanium, Ti-6Al-4V alloy and a cobalt-chromium alloy were cast. Specimens without the primer were also prepared and used as the controls. The shear bond strengths were measured on a screw-driven universal testing machine. RESULTS. The primers significantly(P < .05) improved the shear bond strengths of the heat cure resin to all metals. However, the specimens primed with the Alloy $primer^{(R)}$(MDP monomer) showed higher bond strength than those primed with the MR $bond^{(R)}$(MAC-10 monomer) on titanium. Only adhesive failure was observed at the metal-resin interface in the non-primed specimens, while the primed specimens showed mixed failure of adhesive and cohesive failure. CONCLUSIONS. The use of appropriate adhesive metal primers makes it possible not only to eliminate the need for surface preparation of the metal framework before applying the heat cure resins, but also reduce the need for retentive devices on the metal substructure. In particular, the Alloy $primer^{(R)}$, which contains the phosphoric acid monomer, MDP, might be clinically more acceptable for bonding a heat cure resin to titanium than a MR $bond^{(R)}$, which contains the carboxylic acid monomer, MAC-10.

Comparion of stability in titanium implants with different surface topographies in dogs

  • Kim, Nam-Sook;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Park, Ha-Ok;Lim, Hyun-Pil
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.47-55
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    • 2009
  • STATEMENT OF PROBLEM. A few of studies which compared and continuously measured the stability of various surface treated implants in the same individual had been performed. PURPOSE. We aim to find the clinical significance of surface treatments by observing the differences in the stabilization stages of implant stability. MATERIAL AND METHODS. Eight different surface topographies of dental implants were especially designed for the present study. Machined surface implants were used as a control group. 4 nano-treated surface implants(20 nm $TiO_2$ coating surface, heat-treated 80 nm $TiO_2$ coating surface, CaP coating surface, heat treated CaP coating surface) and 3 micro-treated surface implants [resorbable blast media(RBM) surface, sandblast and acid-etched(SAE) surface, anodized RBM surface] were used as experiment groups. All 24 implants were placed in 3 adult dogs. $Periotest^{(R)}$ & ISQ values measured for 8 weeks and all animals were sacrificed at 8 weeks after surgery. Then the histological analyses were done. RESULTS. In PTV, all implants were stabilized except 1 failed implants. In ISQ values, The lowest stability was observed at different times for each individual. The ISQ values were showed increased tendency after 5 weeks in every groups. After 4 to 5 weeks, the values were stabilized. There was no statistical correlation between the ISQ values and PTV. In the histological findings, the bone formation was observed to be adequate in general and no differences among the 8 surface treated implants. CONCLUSIONS. In this study, the difference in the stability of the implants was determined not by the differences in the surface treatment but by the individual specificity.

Cell response to a newly developed Ti-10Ta-10Nb alloy and its sputtered nanoscale coating

  • Kim, Young-Min;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Lim, Hyun-Pil
    • The Journal of Advanced Prosthodontics
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    • v.1 no.1
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    • pp.56-61
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    • 2009
  • STATEMENT OF PROBLEM. The success of titanium implants is due to osseointegration or the direct contact of the implant surface and bone without a fibrous connective tissue interface. PURPOSE. The purpose of this study was to evaluate the osteoblast precursor response to titanium-10 tantalum-10 niobium(Ti-Ta-Nb) alloy and its sputtered coating. MATERIAL AND METHODS. Ti-Ta-Nb coatings were sputtered onto the Ti-Ta-Nb disks. Ti6-Al-4V alloy disks were used as controls. An osteoblast precursor cell line, were used to evaluate the cell responses to the 3 groups. Cell attachment was measured using coulter counter and the cell morphology during attachment period was observed using fluorescent microscopy. Cell culture was performed at 4, 8, 12 and 16 days. RESULTS. The sputtered Ti-Ta-Nb coatings consisted of dense nanoscale grains in the range of 30 to 100 nm with alpha-Ti crystal structure. The Ti-Ta-Nb disks and its sputtered nanoscale coatings exhibited greater hydrophilicity and rougher surfaces compared to the Ti-6Al-4V disks. The sputtered nanoscale Ti-Ta-Nb coatings exhibited significantly greater cell attachment compared to Ti-6Al-4V and Ti-Ta-Nb disks. Nanoscale Ti-Ta-Nb coatings exhibited significantly greater ALP specific activity and total protein production compared to the other 2 groups CONCLUSIONS. It was concluded that nanoscale Ti-Ta-Nb coatings enhance cell adhesion. In addition, Ti-Ta-Nb alloy and its nanoscale coatings enhanced osteoblast differentiation, but did not support osteoblast precursor proliferation compared to Ti-6Al-4V. These results indicate that the new developed Ti-Ta-Nb alloy and its nanoscale Ti-Ta-Nb coatings may be useful as an implant material.

Establishing a Policy Framework for the Primary Prevention of Occupational Cancer: A Proposal Based on a Prospective Health Policy Analysis

  • Veglia, Amanda;Pahwa, Manisha;Demers, Paul A.
    • Safety and Health at Work
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    • v.8 no.1
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    • pp.29-35
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    • 2017
  • Background: Despite our knowledge of the causes of cancer, millions of workers are involuntarily exposed to a wide range of known and suspected carcinogens in the workplace. To address this issue from a policy perspective, we developed a policy framework based on a prospective health policy analysis. Use of the framework was demonstrated for developing policies to prevent cancers associated with diesel engine exhaust (DEE), asbestos, and shift work, three occupational carcinogens with global reach and large cancer impact. Methods: An environmental scan of existing prospective health policy analyses was conducted to select and describe our framework parameters. These parameters were augmented by considerations unique to occupational cancer. Policy-related resources, predominantly from Canada, were used to demonstrate how the framework can be applied to cancers associated with DEE, asbestos, and shift work. Results: The parameters of the framework were: problem statement, context, jurisdictional evidence, primary prevention policy options, and key policy players and their attributes. Applying the framework to the three selected carcinogens illustrated multiple avenues for primary prevention, including establishing an occupational exposure limit for DEE, banning asbestos, and improving shift schedules. The framework emphasized the need for leadership by employers and government. Conclusion: To our knowledge, this is the first proposal for a comprehensive policy framework dedicated to the primary prevention of occupational cancer. The framework can be adapted and applied by key policy players in Canada and other countries as a guide of what parameters to consider when developing policies to protect workers' health.

Vertical System Testing Method For Efficient Error Tracing (효과적인 오류 추적을 위한 수직적 시스템 시험 방법)

  • Seo, Kwang-Ik;Choi, Eun-Man
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.2
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    • pp.19-29
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    • 2008
  • In case of unit testing, White-box test can be used to closely check source code and to analyze logic and statement errors. On the other hand, in case of function testing of system level, Black-box test can be mainly used to compare actual and expected results by inputting test data because the scale of function is large. This Black-Box test in system testing level has problem in tracing errors in source code when we find errors. Moreover applying White-box test is not easy for system testing level because the levels of test target are different. Therefore this paper suggests the vertical test method of a practical and integrated system level which can checks up to source code level using White-box test style although it aims to test the highly abstract level like a system function. In addition, the experiment explains how to apply the vertical test by displaying an example which traces from UML specification model to the source code and also shows efficiency of error trace.

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THREE DIMENSIONAL FINITE ELEMENT ANALYSIS OF INTERNALLY CONNECTED IMPLANT SYSTEMS (내부연결방식 임플랜트 시스템의 삼차원 유한요소법적 연구)

  • Kim Yu-Lee;Cho Hye-Won;Lee Jai-Bong
    • The Journal of Korean Academy of Prosthodontics
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    • v.44 no.1
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    • pp.85-102
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    • 2006
  • Statement of problem: Currently, there are some 20 different geometric variations in implant/abutment interface available. The geometry is important because it is one of the primary determinants of joint strength, joint stability, locational and rotational stability. Purpose: As the effects of the various implant-abutment connections and the prosthesis height variation on stress distribution are not yet examined this study is to focus on the different types of implant-abutment connection and the prosthesis height using three dimensional finite element analysis. Material and method. The models were constructed with ITI, 3i TG, Bicon, Frialit-2 fixtures and solid abutment, TG post, Bicon post, EstheticBase abutment respectively. And the super structures were constructed as mandibular second premolar shapes with 8.5 mm, 11 mm, 13.5 mm of crown height. In each model, 244 N of vertical load and 244 N of $30^{\circ}$ oblique load were placed on the central pit of an occlusal surface. von Mises stresses were recorded and compared in the crowns, abutments, fixtures. Results: 1. Under the oblique loading, von Mises stresses were larger in the crown, abutment, fixture compared to the vertical loading condition. 2. The stresses were increased proportionally to the crown height under oblique loading but showed little differences with three different crown heights under vertical loading. 3. In the crown, the highest stress areas were loading points under vertical loading, and the finish lines under oblique loading. 4. Under the oblique loading, the higher stresses were located in the fixture/abutment interface of the Bicon and Frialit-2 systems compared to the ITI and TG systems. Conclusions: The stress distribution patterns of each implant-abutment system had difference among them and adequate crown height/implant ratio was important to reduce the stresses around the implants.

THE EFFECT OF SPRUE DESIGN ON THE INTERNAL POROSITY OF TITANIUM CASTINGS (주입선 설계가 티타늄 주조체의 내부기포 발생에 미치는 영향)

  • Heo Sook-Myeong;Jeon Young-Chan;Jeong Chang-Mo;Lim Jang-Seop;Jeong Hee-Chan
    • The Journal of Korean Academy of Prosthodontics
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    • v.44 no.2
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    • pp.147-156
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    • 2006
  • Statement of problem: The high melting temperature and chemical reactivity of titanium necessitates casting machines different from those used in conventional casting. Despite the new developments in Ti casting systems , inadequate mold filling and internal porosity are frequently observed casting defects. Therefore, the study on the fabrication technique including sprue design to solve these casting defects is still necessary. Purpose: The purpose of this study was to evaluate the effect of sprue design and cross sectional area of sprue on the internal porosity. Materials and methods: 30 simulated cast three units titanium crowns were prepared. 5 cast crowns for each with different sprue design(sinlge sprue, double sprue and plate sprue) of two cross sectional areas (small and large cross sectional areas) were fabricated. The sections of titanium castings were photographed in a microscope at ${\times}100$ magnification to record internal porosities. Results and Conclusion: Within the limits of this study, the following conclusions were drawn: 1. There was a significantly lower in internal porosity of titanium castings for large cross sectional area of sprue group than the small group (P<.05) 2. There was no significant difference in internal porosity among sprue designs in similar cross sectional area of sprue (P>.05).