• 제목/요약/키워드: Principally

검색결과 377건 처리시간 0.024초

좌심방내에 발생한 악성 섬유성 조직구종 치험1례 (Primary Malignant Fibrous Histiocytoma of the Left Atrium - A Case Report -)

  • 김택진
    • Journal of Chest Surgery
    • /
    • 제24권4호
    • /
    • pp.357-360
    • /
    • 1991
  • Malignant fibrous histiocytoma is the most common soft tissue sarcoma of late adult life. The tumor occurs principally in one of the extremities or in the abdominal cavity or retroperitoneum, but very rarely in the heart. We report a case of M.F.H. that arose from the posterior wall of the left atrium. A 50 years old woman was presented with signs and symptoms of severe congestive heart failure. On 2-D echocardiographic exam, a huge mass was found in the left atrium. The mass was excised under open heart surgery. Histologic examination revealed that the tumor was actually a malignant fibrous histiocytoma.

  • PDF

STABLE NUMERICAL DIFFERENTIATION: WHEN IS IT POSSIBLE?

  • Ramm, Alexander G.;Smirnova, Alexandra
    • Journal of the Korean Society for Industrial and Applied Mathematics
    • /
    • 제7권1호
    • /
    • pp.47-61
    • /
    • 2003
  • Two principally different statements of the problem of stable numerical differentiation are considered. It is analyzed when it is possible in principle to get a stable approximation to the derivative ${\Large f}'$ given noisy data ${\Large f}_{\delta}$. Computational aspects of the problem are discussed and illustrated by examples. These examples show the practical value of the new understanding of the problem of stable differentiation.

  • PDF

Enzymatic and/or chemical dosages coupled with the clarification of the sample applied to the screening evaluation of heat load in commercial milks

  • Humbert, Gerard
    • 한국유가공학회:학술대회논문집
    • /
    • 한국유가공기술과학회 2005년도 제61회 국제 유가공 심포지움
    • /
    • pp.11-19
    • /
    • 2005
  • Heat treatment is essential for hygienic safety and for extending shelf-life of milk. Heating of milk affects principally its physicochemical, nutritional and organoleptic properties. The most important changes are the decrease in whey protein solubility and the decrease in stability of casein micelles. Maillard reactions are also important and undesirable consequences.

  • PDF

Chromatography separation of proteins by macroporous chitosan and chitin affinity membranes

  • Yuk, Yeong-Jae;Youm, Kyung-Ho
    • 한국막학회:학술대회논문집
    • /
    • 한국막학회 2004년도 Proceedings of the second conference of aseanian membrane society
    • /
    • pp.59-62
    • /
    • 2004
  • Affinity membranes have emerged principally to overcome the problems of limited specificity experienced with membranes that operate purely on a sieving mechanism and as an alternative to the traditional affinity resins. It is a logical expectation that affinity membranes might combine the outstanding selectivity of affinity resins with the high productivity associated with filtration membranes.(omitted)

  • PDF

Optimizaton of A Fuzzy Adaptive Network for Control Applications

  • Esogbue, Augustine O.;Murrell, Janes A.
    • 한국지능시스템학회:학술대회논문집
    • /
    • 한국퍼지및지능시스템학회 1993년도 Fifth International Fuzzy Systems Association World Congress 93
    • /
    • pp.1346-1349
    • /
    • 1993
  • In this paper, we describe the use of certain optimization techniques, principally dynamic programming and high level computational methods, to enhance the capabilities of a fuzzy adaptive neural network controller which we had developed for on-line control and adaption on complex nonlinear processes. Potential applications to an array of processes from diverse fields are discussed.

  • PDF

경영혁신형 중.소 제조기업 선정 모형에 관한 연구 (A Study on Selecting Model for Small and Medium Management Innovative Manufacturers)

  • 유연우;노재확
    • 한국전자거래학회지
    • /
    • 제15권2호
    • /
    • pp.55-75
    • /
    • 2010
  • 본 연구는 정부가 경영혁신형 중소기업 선정에 사용되는 모형을 찾는 것을 첫 번째 목표로 삼고, 그 결과를 이용하여 현재의 선정 지표의 가중치 개선의 방향은 무엇인가를 찾는 것을 부차적 목적으로 삼았으며, 먼저, 경영혁신형 중소기업 선정에 사용되는 원래의 지표 변수(10개)를 독립요인으로 변환하여 본 결과 3개의 지표가 통계적 유의성이 없는 것으로 나타났다. 본 연구에서 비교한 3가지 선정 모델은 원 변수 사용모형, 9개 독립 요인모형, 7개 독립 요인모형 이다. 3개의 모형 중에서 7개의 독립 요인으로 추정한 모형의 설명력이 다른 2개의 모형보다 높은 것으로 나타났으며, 기존 선정 지표의 가중치 개선도 이를 반영한 방향으로 개선된다면 모형의 신뢰도를 높일 수 있을 것으로 본다. 7개의 독립 요인으로 추정한 모형을 다시 원래의 10개 변수의 영향력으로 복원하여 그 설명력을 최초의 변수들과 비교한 결과 조직프로세스, 마케팅관리, 관리프로세스, 생산설비 현황, 예측수준 등이 실제 선정 시에는 더 큰 영향을 주는 것으로 나타났으며 혁신전략, 지식정보관리, 성과수준, 운영수준 등은 실제 측정되는 지표상의 가중치에 비하여 영향력이 적은 것으로 나타났다.

새로운 항정신병약물의 약물상호작용 (Drug Interaction in New Antipsychotics)

  • 김용식;강웅구;노명선
    • 생물정신의학
    • /
    • 제7권1호
    • /
    • pp.14-20
    • /
    • 2000
  • Recently atypical antipsychotics have been used as first line agent in the treatment of schizophrenia, and also played a significant role in the treatment of many kinds of psychiatric disorders. The pharmacokinetic and pharmacodynamic properties of these newer antipsychotics are well known through preclinical and early clinical trials. However, it is important to note the limitations of the results due to its relatively short experience. Clozapine is eliminated principally by the hepatic P450 1A2 and 3A4 cytochrome enzymes. 1A2 inducers such as carbamazepine and smoking can reduce its half-life, while 1A2 inhibitors such as SSRIs, especially fluvoxamine can increase its duration of action. Carbamazepine should be avoided in a patient on clozapine because of carbamazepine's potential effects on bone marrow. Benzodiazepines tend to increase the chances of sedation, delirium and respiratory depression. Risperidone is metabolized to 9-hydroxyriperidone by the hepatic P450 2D6 cytochrome enzymes. Fluoxetine and paroxetine, 2D6 inhibitors interfere with metabolism, but 9-hydroxyrisperidone has similar biological activity as parental drug, so it has little affect on the outcome. Olanzapine shows minimal capacity to inhibit cytochrome P450 isoenzymes and shows minimal chance of drug interaction. It is eliminated principally by the hepatic P450 1A2 and 2D6 cytochrome enzymes.

  • PDF

플라이 애쉬 치환율에 따른 콘크리트의 염소이온 투과특성 (Effect of Fly-Ash on the Characteristic of Chloride ion Penetration in Concrete)

  • 하재담;김태홍;유재상;이종열;박찬규;김상윤
    • 한국콘크리트학회:학술대회논문집
    • /
    • 한국콘크리트학회 2002년도 가을 학술발표회 논문집
    • /
    • pp.39-42
    • /
    • 2002
  • Cloride attack of concrete is one of the important causes of corrosion of reinforcing steel in concrete with carbonation and frost damage. In this paper, the effect of fly-ash on the cloride attack were investigated by varying water binder ratio and fly-ash contents according to the chloride ion penetrationa test. (ASTM C 1202-94) The principal conclusions from this research were as follows: 1) The compressive strength of concrete at large ages, depends more on $C_2$S contents of base cement than fly-ash contents. 2) On the other hand, the chloride ion penetration of concrete at large ages, principally depends on fly-ash contents and the influence of type of base cement is insignificant.

  • PDF

상하부 스툴을 고려한 파형 격벽 최적 설계에 관한 연구 (A Study on Optimum Structural Design of the Corrugated Bulkhead Considering Stools)

  • 신상훈;남성길
    • 대한조선학회논문집
    • /
    • 제40권4호
    • /
    • pp.53-58
    • /
    • 2003
  • Design of the corrugated watertight bulkhead for a bulk carrier is principally determined by the permissible limit of Classification requirements. As the weight of upper and lower stool has considerable portion of the total weight of the transverse bulkhead, optimum design including the stool geometry and size will play an important role on economic shipbuilding. The purpose of this study is focused on the minimization of steel weight using the design variables, which are the shape and the size of the corrugation as well as the upper and lower stools. Discrete variables are used as design variables for the practical design. In this study, the evolution strategies (ES), which can highly improve the possibility of leaching the global minimum point, are selected as an optimization method. Usefulness of this study is verified by comparison with the proven type ship design. As objective function, total weight of the transverse bulkhead including the upper and lower stools is used.

한국 관박쥐의 정자발생과 자성생식관내의 정자운명에 관한 연구 (A Study on the Spermatogenesis and Spermatozoan Fate in the Female Reproductive Tract of the Korean Greater Horseshoe Bat (Rhinolophus ferrumequinum korai))

  • 김은주;오영근
    • Applied Microscopy
    • /
    • 제21권2호
    • /
    • pp.14-28
    • /
    • 1991
  • The present study was designed in order to clarify ultrastructural characteristies of the spermatogenetic process and to examine survival state of the spermatozoa introduced into the female reproductive tract after autumnal coitus in the Korean greater horseshoe bats(Rhinolophus ferrumeguinum korai). The general morphological characteristics of spermatogenesis were principally similar to those of the other mammalian species; acrosomal formation, flagellar formation, middle piece formation and concentration of the spermatozoan nucleus. The spermatozoa introduced into the vagina were found to be dead forming a vaginal plug, the opaque central core of which consisted of trapped dead spermatozoa. Some spermatozoa introduced into the uterus were observed to be phagocytized by the polymorphonuclear leucocytes infiltrated into the uterine glandular lumen. The oviductal epithelium, consisted of ciliated and secretory cells; the luminal surface of secretory cells were covered by a number of microvilli with well developed glycocalyx, suggesting a close relationship to nutrient (e.g. glycogen) supply for the spermatozoa during hibernation.

  • PDF