• Journal of Chest Surgery
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• v.42 no.4
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• pp.473-479
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• 2009

Background: Retrograde autologous priming (RAP) is known to be useful in decreasing the need of transfusions in cardiac surgery because it prevents excessive hemodilution due to the crystalloid priming of cardiopulmonary bypass circuit. However, there are also negative side effects in terms of blood conservation. We analyzed the intraoperative blood-conserving effect of RAP and also investigated the efficacy of autotransfusion and ultrafiltration as a supplemental method for RAP. Material and Method: From January 2005 to December 2007, 117 patients who underwent isolated coronary artery bypass operations using cardiopulmonary bypass (CPB) were enrolled. Mean age was 63.9$\pm$9.1 years (range 36$\sim$83 years) and 34 patients were female. There were 62 patients in the RAP group and 55 patients in he control group. Intraoperative autotransfusion was performed via the arterial line. RAP was done just before initiating CPB using retrograde drainage of the crystalloid priming solution. Both conventional (CUF) and modified (MUF) ultrafiltrations were done during and after CPB, respectively. The transfusion threshold was less than 20% in hematocrit. Result: Autotransfusions were done in 79 patients (67.5%) and the average amount was 142.5$\pm$65.4 mL (range 30$\sim$320 mL). Homologous red blood cell (RBC) transfusion was done in 47 patients (40.2%) and mean amount of transfused RBC was 404.3$\pm$222.6 mL. Risk factors for transfusions were body surface area (OR 0.01, 95% CI 0.00 $\sim$ 0.63, p=0.030) and cardiopulmonary bypass time (OR 1.04, 95% CI 1.01 $\sim$ 1.08, p=0.019). RAP was not effective in terms of the rate of transfusion (34.5% vs 45.2%, p=0.24). However, the amount of transfused RBC was significantly decreased (526.3$\pm$242.3ml vs 321.4$\pm$166.3 mL, p=0.001). Autotransfusion and ultrafiltration revealed additive and cumulative effects decreasing transfusion amount (one; 600.0$\pm$231.0 mL, two; 533.3$\pm$264.6 mL, three; 346.7$\pm$176.7 mL, four; 300.0$\pm$146.1 mL, p=0.002). Conclusion: Even though RAP did not appear to be effective in terms of the number of patients receiving intraoperative RBC transfusions, it could conserve blood in terms of the amount transfused and with the additive effects of autotransfusion and ultrafiltration. If we want to maximize the blood conserving effect of RAP, more aggressive control will be necessary - such as high threshold of transfusion trigger or strict regulation of crystalloid infusion, and so forth.

• Journal of Korean Elementary Science Education
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• v.27 no.1
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• pp.9-22
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• 2008

The purpose of this study was to investigate the type of classification criterion and the characteristic of classification strategy that appear in pre-service elementary teachers' classification activity. The 4 tasks were developed for classification activity; button as a real things that attribute is prominent, shell as a real things that attribute is less prominent, snow flake as a picture cards that attribute is prominent, and galaxy as a picture cards that attribute is less prominent. The 5 college students who major in elementary education were selected. Data were collected by interview with participants, participants' classification recording paper, investigator's observation of participants' action observation, and videotaped that record participants' subject classification process. Result proved in this study is as following. First, pre-service elementary teachers used 4 qualitative classification criterion of feature, random field, image and secondary property, and used 2 dimension classification criterion of space and quantity. They used single quality classification criterion or combining dimension classification criterion in classification activity. Second, pre-service elementary teachers have classification strategy that apply each various classification criterion, and also classification strategy are different according to subject, but discussed that "anchor" and "priming effect" are important for effective classification. Result of this study is expected to contribute classification research and classification teaching program development.

• The Journal of the Korean Society for Microbiology
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• v.20 no.1
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• pp.103-107
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• 1985

Female ICR mice were vaccinated against Toxoplasma gondii(RH strain), infected 2 weeks later and after recovery mated to normal ICR males. Control matings were with normal ICR females. The progeny of the above matings were weaned at 1 week, vaccinated at 1, 2, 3, 4 or 5 weeks of age and infected 2 weeks later with lethal Toxoplasma tachyzoites. As assessed by survival, the effectiveness of vaccination among offspring of vaccinated-recovered mothers was greatly impaired than that of control mice, with respective of age : where mice did survive, recovery was greatly delayed relative to the controls. The protective effect of vaccination among infants born to control mothers was also blocked by maternal specific antibodies, by administration of high-titered specific antibodies or by transfer of nylon wool adherent immune-spleen cells, but was augmented by transfer of nylon wool passed immune-spleen cells. These results indicate that this impairment of vaccination may be due to the transmission of maternal specific antibodies to the offspring which acts to suppress both priming by the vaccine and the generation of parasite-specific helper T cells.

• Journal of Microbiology and Biotechnology
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• v.9 no.4
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• pp.464-468
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• 1999

The effectiveness of current biodegradation test methods for degradable polymers under controlled composting conditions was studied in regards to the test temperature and compost condition. When biodegradability tests for the natural (starch, cellulose, PHB/HV) and synthetic (PCL, SG, PLA) polymers were conducted at temperature levels of 35 and $55^{\circ}C$ with compost cured at ambient temperature, the degradations of cellulose and starch were higher at $35^{\circ}C$ because of the priming effect. On the other hand, degradations of other polymers were higher at $55^{\circ}C$. In the biodegradation test at $55^{\circ}C$, compost harvested right after the thermophilic degradation stage showed higher biodegradation activities than the cured compost for both the synthetic aliphatic polyester (SG) and a natural polymer, cellulose. These results suggest that the biodegradation test conducted at $55^{\circ}C$ with the compost, harvested right after the thermophilic degradation stage during composting, showed the highest biodegradation activity under controlled composting conditions.

• Proceedings of the KIEE Conference
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• 2003.10a
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• pp.229-232
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• 2003

AC PDP의 ADS 추동 방식은 구동 방법이 간단하여 구현하기가 용이할 뿐만 아니라 가장 안정적인 구동 방식으로 널리 사용되고 있다 [1]. 그러나 ADS 구동 방식은 주사선의 수가 늘어남에 따라 어드레싱에 필요한 시간이 증가하게 되고 유지방전 구간에 할애할 시간이 상대적으로 감소하게 되어 휘도가 저하되게 되는 문제점을 갖고 있다. 이러한 문제를 해결하기 위하여 어드레싱 시간을 최소화하기 위한 고속 어드레싱 기술에 대한 연구가 계속하여 진행되고 있다 [2-10]. 본 논문에서는 고속 구동 시에 나타나는 불안정한 어드레싱으로 인한 화질의 저하문제를 해결하기 위한 개선된 ADS 구동파형을 제시한다. 초기화 구간의 Reset 파형은 어드레싱 추간의 특성에 중요한 영향을 미치게 되는데, Reset 구간에서 생성된 벽전하를 어드레싱 방전구간 동안 지속적으로 유지되게 함으로서 어드레싱 방전전압을 줄이고 안정적인 어드레싱이 유지될 수 있도록 하였다. 본 논문에서는 Priming Effect의 영향이 급격히 감소하는 80us 이후, 벽전하의 생성을 돕는 Wall Charge Acceleration Pulse를 적용함으로서 불안정한 어드레싱 문제를 해결할 수 있는 방법을 제시하였고 휘도의 불균등화로 인한 화질 저하의 문제를 해결하였다.

• Journal of Chest Surgery
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• v.32 no.4
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• pp.364-367
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• 1999

Background: The efficacy of the hemostasis of prophylactic aprotinin after cardiac valve replacement was evaluated from January 1994 to December 1996 at Pusan National University Hospital. Material and Method: In a randomized study, 20 patients received aprotinin(2${\times}$106 KIU as a loading dose for 30 minutes after anesthesia, 1${\times}$106 KIU for priming and 5${\times}$105 KIU/hr as a maintenance dose from the completion of loading dose till skin closure) and another 20 untreated patients served as controls. Result: Aprotinin produced a significant reduction in postoperative blood loss compared with controls and significantly decreased total exposure to allogenic blood products compared with the control group(p<0.05). Conclusion: We conclude that aprotinin effectively reduces postoperative blood loss and trasfusion in patient undergoing cardiac valve replacement.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.46 no.4
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• pp.321-324
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• 2001

Tobacco seeds (Nicotiana tabacum L. cv KF109) were primed in the polyethylene glycol 6000(PEG) solution and then stored at 5 and $25^{\circ}C$ under 40, 60 and 80% relative humidity (RH) conditions for six months. The effect of storage temperature and humidity on mean germination time ($T_{50}$), longevity and germination of the primed tobacco seeds were compared. Untreated seeds (control) stored at $5^{\circ}C$ showed high germinability throughout the entire storage period and humidity, and a decline in germinability showed after 6 months at 60% RH and after 3 months at 80% RH when stored at $25^{\circ}C$, Primed seeds retained high germinability until 6 months at 60% RH and 3 months at 80% RH when stored at $5^{\circ}C$ but showed a significant decline in germinability after 3 months at 40% RH, and 1 months at 60% and 80% RH, respectively when stored at $25^{\circ}C$, Primed seeds were completely lost viability when stored at $25^{\circ}C$ under 60% RH for 6 months and under 80% RH for 3 months.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.3
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• pp.38-43
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• 2011

A CNG/diesel dual-fuel engine uses CNG as the main fuel and injects a small amount of diesel as an ignition priming. This study proposed the modification of the existing diesel engine into a dual-fuel engine that injects diesel with a high pressure by common rail direct injection (CRDI) and by injecting CNG at the intake port for premixing. And experiment was progressed for understanding about effect of CNG mixing ratio. The CNG/diesel dual-fuel engine showed equally satisfactory coordinate torque and power regardless of CNG mixing ratio. The PM emission was low at any CNG mixing ratio because of very small diesel pilot injection. In case of NOx and HC, high CNG mixing ratio showed low NOx and HC emissions at low speed. At medium & high speed, low CNG mixing ratio showed low NOx and HC emissions. Therefore, it would be optimized by controlling CNG mixing ratio.

• Journal of Distribution Science
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• v.21 no.12
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• pp.127-140
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• 2023

Purpose: In a situation where the local economy and alley economy are stagnant, efforts to revitalize the role of small business owners need a virtuous cycle system through consumers' consumption power, not just cash support. Research design, data, and methodology: The study site focuses on Daedeok-gu, the first to introduce local currency as a policy. In the case of the store survey, 254 stores out of 300 stores registered with local currency were analyzed, and the consumer survey was conducted on 1,394 out of 1,500 local people using local currency. Statistical analysis was performed using the SPSS. Result: As a result of time-series checking whether local economic activities are carried out smoothly due to the nature of the local currency, the average daily sales of Daedeok-gu increased by 388,980won compared to 2019. This proved through empirical research in the region that local currency played a priming role in bringing opportunities and rehabilitation to the local commercial districts and small business owners. Conclusions: In the monetary function of simply buying and selling value through payment, points supported as incentives can be used as local currency while inducing direct participation in solving social problems, and the concurrent effect of causing problem-solving and regional economic vitality began to sprout.

• IMMUNE NETWORK
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• v.11 no.1
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• pp.79-94
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• 2011

Background: Dendritic cell (DC)-based vaccines are currently being evaluated as a novel strategy for tumor vaccination and immunotherapy. However, inducing long-term regression in established tumor-implanted mice is difficult. Here, we show that deoxypohophyllotoxin (DPT) induces maturation and activation of bone marrow-derived DCs via Toll-like receptor (TLR) 4 activation of MAPK and NF-${\kappa}B$. Methods: The phenotypic and functional maturation of DPT-treated DCs was assessed by flow cytometric analysis and cytokine production, respectively. DPT-treated DCs was also used for mixed leukocyte reaction to evaluate T cell-priming capacity and for tumor regression against melanoma. Results: DPT promoted the activation of $CD8^+$ T cells and the Th1 immune response by inducing IL-12 production in DCs. In a B16F10 melanoma-implanted mouse model, we demonstrated that DPT-treated DCs (DPT-DCs) enhance immune priming and regression of an established tumor in vivo. Furthermore, migration of DPT-DCs to the draining lymph nodes was induced via CCR7 upregulation. Mice that received DPT-DCs displayed enhanced antitumor therapeutic efficacy, which was associated with increased IFN-${\gamma}$ production and induction of cytotoxic T lymphocyte activity. Conclusion: These findings strongly suggest that the adjuvant effect of DPT in DC vaccination is associated with the polarization of T effector cells toward a Th1 phenotype and provides a potential therapeutic antitumor immunity.