• Toxicological Research
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• 제17권
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• pp.135-138
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• 2001

Female Wistar rats were randomly divided into 5 groups: Control, received distilled water; Low lead, received 0.5 g/ιlead (as acetate) in drinking water; High lead, received 2.0 g/ιlead; Low lead + Minerals, received 0.5 g/ιlead in drinking water and received minerals (Ca$^{2+}$, 25 mg/kg/day; Fe$^{3+}$, 0.47 mg/ kg/day; Zn$^{2+}$, 0.33 mg/kg/day; Se, 0.83 $\mu\textrm{g}$/kg/day) by gavage; High lead + Minerals, received 2.0 g/ιlead and received the same minerals. Animals exposure to lead was from 10 days before mating till postnatal day 21; and the minerals was administered from the first day of pregnancy and during lactation. No statistical difference was found either in body weights or in blood lead levels between the pups received minerals and those only exposed to lead at the same dose. The developmental and behavioral teratological effects of lead on pups, such as time-lag of eye opening, pinna detachment, fur developing, incisor eruption, ear unfolding, and surface righting were observed in this study; and the minerals decreased the toxicity of lead either in low or in high lead exposure pups. The numbers of step-down were significantly increased in lead exposed animals, and the effect of intervention by the minerals was appeared only in the pups exposed to low lead. The ChAT activity and levels of glutamate and aspartate in hippocampus decreased in treated animals compared to control animals, no effect of intervention by the minerals was found. The results of this study indicate that the applied multi-minerals can alter the outcome of develop-mental lead poisoning in rats.s.s.s.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2000년도 제52차 추계학술대회 연제집
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• pp.93-94
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• 2000

• 보건교육건강증진학회지
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• 제24권1호
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• pp.1-16
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• 2007

Objctives: This study purposed to examine the intention to participate in the preventive program of depression of Internet user and to offer the baseline data for development of mental health promotion program. Methods: The internet survey was performed using a self-reported questionnaire on intention to participate in the preventive program of depression, depressive symptom(with Zung's SDS) and so forth from 1,000 internet user (aged $13{\sim}49$ years) via two web sites at Feb($1st{\sim}10th$), 2006. We analyzed the intention to participate in preventive program of depression and the factors related with that intention by depressive level. Results: In the normal group, the intention to participate in a preventive program of depression was influenced significantly by counselling experience(s) on depression(p<.001), and perceived control(p<.001) over the barriers to participation in the preventive program of depression, and marginally by gender. In the depressive group, the smoking habit revealed marginal effect(p=.051) and perceived control over the barriers to participation in the preventive program of depression influenced on that intention significantly(p<.001). Conclusion: Among internet users, especially the solutions of barriers to participate in the preventive program of depression is more important at the intervention program for prevention of depression. In the normal group, we need to consider the use of messages tailored by counselling experience(s) on depression. Some intervention program dealing with two subjects, smoking cessation and prevention of depression concurrently, will be appropriate for the depressive group.

• Nutrition Research and Practice
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• 제6권2호
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• pp.138-145
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• 2012

The objective of this study was to evaluate the effect of a healthy school tuck shop program, developed as a way of creating a healthy and nutritional school environment, on students' access to healthy foods. Five middle schools and four high schools (775 students) participated in the healthy school tuck shop program, and nine schools (1,282 students) were selected as the control group. The intervention program included restriction of unhealthy foods sold in tuck shops, provision of various fruits, and indirect nutritional education with promotion of healthy food products. The program evaluation involved the examination of students' purchase and intake patterns of healthy foods, satisfaction with the available foodstuffs, and utilization of and satisfaction with nutritional educational resources. Our results indicated that among of the students who utilized the tuck shop, about 40% purchased fruit products, showing that availability of healthy foods in the tuck shop increased the accessibility of healthy foods for students. Overall food purchase and intake patterns did not significantly change during the intervention period. However, students from the intervention schools reported higher satisfaction with the healthy food products sold in the tuck shop than did those from the control schools (all $P$ < 0.001), and they were highly satisfied with the educational resources provided to them. In conclusion, the healthy school tuck shop program had a positive effect on the accessibility of healthy food. The findings suggest that a healthy school tuck shop may be an effective environmental strategy for promoting students' access to healthy foods.

• Journal of Preventive Medicine and Public Health
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• 제44권3호
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• pp.101-110
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• 2011

Objectives: Screening for colorectal cancer is considered cost effective, but is underutilized in the U.S. Information on the efficiency of "tailored interventions" to promote colorectal cancer screening in primary care settings is limited. The paper reports the results of a cost effectiveness analysis that compared a survey-only control group to a Centers for Disease Control (CDC) web-based intervention (screen for life) and to a tailored interactive computer-based intervention. Methods: A randomized controlled trial of people 50 and over, was conducted to test the interventions. The sample was 1224 partcipants 50-70 years of age, recruited from Kelsey-Seybold Clinic, a large multi-specialty clinic in Houston, Texas. Screening status was obtained by medical chart review after a 12-month follow-up period. An "intention to treat" analysis and micro costing from the patient and provider perspectives were used to estimate the costs and effects. Analysis of statistical uncertainty was conducted using nonparametric bootstrapping. Results: The estimated cost of implementing the web-based intervention was $40 per person and the cost of the tailored intervention was $45 per person. The additional cost per person screened for the web-based intervention compared to no intervention was $2602 and the tailored intervention was no more effective than the web-based strategy. Conclusions: The tailored intervention was less cost-effective than the web-based intervention for colorectal cancer screening promotion. The web-based intervention was less cost-effective than previous studies of in-reach colorectal cancer screening promotion. Researchers need to continue developing and evaluating the effectiveness and costeffectiveness of interventions to increase colorectal cancer screening.

• Journal of Preventive Medicine and Public Health
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• 제46권sup1호
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• pp.22-27
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• 2013

The purpose of this study was to examine the beneficial effects of a new cognitive intervention program designed for the care and prevention of dementia, namely Learning Therapy. The training program used systematized basic problems in arithmetic and Japanese language as training tasks. In study 1, 16 individuals in the experimental group and 16 in the control group were recruited from a nursing home. In both groups, all individuals were clinically diagnosed with senile dementia of the Alzheimer type. In study 2, we performed a single-blind, randomized controlled trial in our cognitive intervention program of 124 community-dwelling seniors. In both studies, the daily training program using reading and arithmetic tasks was carried out approximately 5 days a week, for 15 to 20 minutes a day in the intervention groups. Neuropsychological measures were determined simultaneously in the groups both prior to and after six months of the intervention. The results of our investigations indicate that our cognitive intervention using reading and arithmetic problems demonstrated a transfer effect and they provide convincing evidence that cognitive training maintains and improves the cognitive functions of dementia patients and healthy seniors.

• 대한간호학회지
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• 제41권5호
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• pp.715-723
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• 2011

Purpose: This study was done to evaluated the effects of Human Papillomavirus (HPV) vaccination education on college women's knowledge of HPV, health beliefs (perceived severity and perceived susceptibility), and preventive behavior intention. Methods: A nonequivalent control group pretest-posttest design with repeated measures was used. Participants were 125 female college students in one university, assigned to an experimental group (72 students) and control group (53 students). Results: Two weeks after the intervention, the experimental group reported higher scores of knowledge, perceived severity, perceived susceptibility, and preventive behavior intention than the control group. All follow-up scores except intention measured at 5 weeks after the intervention from the experimental group remained still higher than those from the control group. Conclusion: The results suggest that the variable of preventive behavior intention which is believed to be the closest predictor of real vaccination rate could be affected by the education, but did not remain at the same level at 5 weeks. Therefore, additional interventions may need to be provided before the educational effect on preventive behavior intention is greatly diminished.

• 대한예방한의학회지
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• 제22권1호
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• pp.29-44
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• 2018

Objectives : This study was conducted to survey on the research trends of Traditional Korean Medicine(TKM) intervention with woman menopausal symptoms in Korea. Method : We searched Korean research database by using keyword 'Menopause'. Korean research databases were Korean Studies Information Service System(KISS), Research Information Service System(RISS) and Korean Medicine Information System(OASIS). We classified articles identified by TKM treatments. Results : We analyzed 63 studies by classifying 4 interventions that consist of acupuncture treatment, herbal medicine, lifestyle modification, complex therapy. According to studies using acupuncture, Sameumgyo(三陰交, SP6) was the most treated. Soyosan(逍遙散) was most treated in herbal medicine studies, and massage was most used in lifestyle modification. Conclusion : A variety of treatment using TKM have been used for menopausal women. It is necessary to increase the level of evidence of TKM intervention through additional studies in the future.

• 한국사회복지학
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• 제44권
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• pp.318-345
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• 2001

The purpose of this research was to develop and evaluate a preventive mental health program for the depression among the elderly in community. Based on the review of literature, intervention program for preventing depression among the elderly was developed. In particular, the program focuses on enhancing the sense of control which is from social cognitive theory. The preventive mental health program consists of two parts: Tan-Hak and Social intervention program. Tan-Hak was oriented to cognitive change and activities, while social intervention program dealt with some social skills for relationship, stress management, motivation of social activities (volunteer activities), positive future designing, etc. For the evaluation of this program, we employed depression scale and medical measurement such as hormone test before and after the program, and in-depth interview of subjects. Overall, this program was successful in some points. First, through the pre and post test, this program has positive effect on strengthening the sense of control, and consequently, lowering depression level. Secondly, 18 people started this program called "smile class" at first time, and none of them turned out until the end of the program. This implies that the program was interesting to the elderly.

• 한국간호교육학회지
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• 제23권4호
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• pp.398-408
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• 2017

Purpose: This study aims to identify the effect of pediatric fall prevention education with leaflets and picture books on the fall-related knowledge and preventive behaviors in caregivers of inpatient children. Methods: This study is a non-equivalent control group non-synchronized design. It divided 62 caregivers of inpatient children aged 5 and under into an experimental group and a control group in P general hospital located in B City. Results: Fall related knowledge score in the experimental group was increased by 2 points after the intervention and the score in the comparison group was increased by 0.1 points. The difference after the intervention in fall related knowledge scores between the two groups was statistically significant (t=7.67, p<.001). The fall related prevention behavior score of the experimental group increased by 9.3 points after the intervention, and the score of the comparison group increased by 2.5 points. The difference in the scores of fall related prevention behaviors between the two groups was statistically significant (t=5.71, p<.001). Conclusion: Pediatric inpatient fall prevention education using leaflets and picture books can improve caregivers' fall-related knowledge and preventive behaviors. In turn, this can reduce children's falls in pediatric wards in general hospitals.