• Title/Summary/Keyword: Prevention of CAD

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The Characteristics of Risk Factors in Korean CAD Patients Comparing to American Counterpart and Its Implications to Prevention of CAD

  • Kim, Wan-Soo
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.2
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    • pp.9-20
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    • 2017
  • PURPOSE: The purpose of this study is to understand the difference in the risk factors of coronary artery disease (CAD) between Korean and American CAD patients to determine the discriminant factor for each group, as well as to provide useful information to be reflected in the national concern of health. METHODS: Data were collected from 248 Korean and 107 American CAD patients who underwent either percutaneous coronary intervention or coronary artery bypass grafting. By using t-test and $X^2$-test, risk factors were compared between the Koreans and Americans. To elucidate which risk factor was the most discriminant for each group, logistic regression analysis was performed. RESULTS: All risk factors, except diastolic blood pressure, showed a significant difference between the two groups. $X^2$-test showed statistical significance with respect to the smoking rate between the female groups. Moreover, there was a statistically significant difference between the two groups regarding blood total cholesterol (TC) and triglyceride, and between the male groups, here was a statistically significant difference with respect to blood high-density lipoprotein cholesterol (HDL). Diabetes mellitus (DM) was the most discriminant factor for Korean patients while TC/HDL is the most discriminant for the Americans. CONCLUSION: The characteristics of CAD risk factors were determined to be different between Koreans and Americans in this study. TC/HDL was a discriminant factor for Americans while DM was a discriminant factor for Koreans. This result implies that DM should primarily be given attention to prevent CAD in Korean adults.

Correlation Between Expression of Cell Adhesion Molecules CD44 v6 and E-cadherin and Lymphatic Metastasis in Non-small Cell Lung Cancer

  • Su, Chong-Yu;Li, Yun-Song;Han, Yi;Zhou, Shi-Jie;Liu, Zhi-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2221-2224
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    • 2014
  • Objective: To explore the relationship between expressions of cell adhesion molecules CD44 v6 and E-cadherin (E-cad) and lymphatic metastasis in non-small cell lung cancer (NSCLC). Materials and Methods: Eightyseven tissue samples obtained from patients with primary NSCLC were collected in our hospital from Dec., 2007 to Dec., 2012, and the expressions of CD44 v6 and E-cad gene proteins in these samples were detected by immunohistochemical method. Results: In the tissue without lymphatic metastasis, the positive expression rate of CD44 v6 was significantly lower, whereas the normal expression rate of E-cad was notably higher than that with lymphatic metastasis (55.6% vs. 78.4%, 47.2% vs. 21.6%), and both differences had statistical significance (P<0.05). Besides, CD44 v6 and E-cad expressions had a significant correlation in the NSCLC tissue with lymphatic metastasis (P<0.05). Conclusions: The positive expression of CD44 v6 and abnormal expression of E-cad may play a very important role in promoting lymphatic metastasis of NSCLC, with synergistic effect. Hence, detection of CD44 v6 and E-cad expressions is conductive to judging the lymphatic metastasis in NSCLC.

A basic study on improvement of Disasters Prevention System using space information from 3D CAD - focused on Multiple-use Facilities - (3D CAD 공간 정보를 활용한 방재 시스템 개선에 관한 기초 연구 - 다중이용시설물 중심으로 -)

  • Lee, Myoung-Hoon;Ahn, Byung-Ju;Kim, Jae-Jun
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2009.05b
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    • pp.189-193
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    • 2009
  • As large-scale buildings, skyscrapers, and multi-purpose buildings recently increase in numbers dramatically the internal space of such buildings becomes more and more large and complicated accordingly. The Multi-purpose buildings are increasing rapidly in number, and concerns over the evacuation process in case of fire emergency are also increasing. However, A controller who is responsible for visitor's safety makes a decision about measures for visitor safety in human based decision making process. Many potential accidents that are caused by human error lurk in results of the process. The accidents can be decreased by changing the decision making process from human-based into technology-based. Through this study, the way to improve current disasters prevention system is presented and it can also improve shelter inducement methods effectively. SICS(Spatial Information Control System) which is being studied in other research is used as the tool for improvement.

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Impact of Risk Factors, Autonomy Support and Health Behavior Compliance on the Relapse in Patients with Coronary Artery Disease (관상동맥질환 위험요인, 자율성 지지 및 건강행위 이행이 관상동맥질환자의 재발에 미치는 영향)

  • Park, Ae Ran;So, Hyang Sook;Song, Chi Eun
    • Korean Journal of Adult Nursing
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    • v.29 no.1
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    • pp.32-40
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    • 2017
  • Purpose: The purpose of this secondary data analysis was to identify factors influencing a relapse among patients with coronary artery disease (CAD). Methods: Of 250 participants enrolled in the original study 75 were selected as there was no relapse for more than one year following the initial treatment and 54 were selected because there was a relapse. Data were analyzed using ${\chi}^2$ test, t-test or F test to determine if there were any significant differences in the study variables relative to the status of relapse. Predictors were calculated by logistic regression. Results: Autonomy supported by healthcare providers was the significant predictor for relapse in patients with CAD. Patients with low autonomy supported by healthcare providers was 3.91 times more likely to relapse than patients with high autonomy supported. Patients with diabetes were at greater risk of recurrence. Conclusion: Secondary prevention of CAD is a major task for patients with CAD. Behavioral strategies for cardiovascular risk reduction are essential and autonomy supported by healthcare providers should be included in their strategies.

Cancer Risk from Medical Radiation Procedures for Coronary Artery Disease: A Nationwide Population-based Cohort Study

  • Hung, Mao-Chin;Hwang, Jeng-Jong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2783-2787
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    • 2013
  • To assess the risk of cancer incidence after medical radiation exposure for coronary artery disease (CAD), a retrospective cohort study was conducted based on Taiwan's National Health Insurance Research Database (NHIRD). Patients with CAD were identified according to the International Classification of Diseases code, 9th Revision, Clinical Modification (ICD-9-CM), and their records of medical radiation procedures were collected from 1997 to 2010. A total of 18,697 subjects with radiation exposure from cardiac imaging or therapeutic procedures for CAD were enrolled, and 19,109 subjects receiving cardiac diagnostic procedures without radiation were adopted as the control group. The distributions of age and gender were similar between the two populations. Cancer risks were evaluated by age-adjusted incidence rate ratio (aIRR) and association with cumulative exposure were further evaluated with relative risks by Poisson regression analysis. A total of 954 and 885 subjects with various types of cancers in both cohorts after following up for over 10 years were found, with incidences of 409.8 and 388.0 per 100,000 person-years, respectively. The risk of breast cancer (aIRR=1.85, 95% confidence interval: 1.14-3.00) was significantly elevated in the exposed female subjects, but no significant cancer risk was found in the exposed males. In addition, cancer risks of the breast and lung were increased with the exposure level. The study suggests that radiation exposure from cardiac imaging or therapeutic procedures for CAD may be associated with the increased risk of breast and lung cancers in CAD patients.

A Study on Flooding Prevention Scheme due to Sea Level Rise at Young-do Coast in Busan (부산 영도 해안의 해수면 상승에 따른 침수대책 연구)

  • Hong, Sung-Ki;Kang, Yong-Hoon;Lee, Han-Seok
    • Journal of Navigation and Port Research
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    • v.37 no.4
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    • pp.409-418
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    • 2013
  • On the assumption of the rise of sea level, the inundation vulnerabilities on coastal areas of Korea are evaluated in different ways. The propose of this study is to find out the influences of sea level rise caused by global warming at Young-do coastal area, and to suggest the prevention schemes against the flooding damage caused by the sea level rise. The potential rates of sea level rise are assumed and with these rates the inundation vulnerabilities are simulated using CAD program. With the virtual maps, as the results of the previous CAD simulation, this study attempts to suggest the flood prevention schemes for each sector of damage-expected coastal area.

Computerization for Management of Street Tree Using CAD (CAD를 이용한 가로수 관리 전산화에 관한 연구)

  • 허상현;심경구
    • Journal of the Korean Institute of Landscape Architecture
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    • v.29 no.2
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    • pp.68-76
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    • 2001
  • The purpose of this study is to computerize street tree management using a CAD program in order to manage the drawing record of street trees systematically and concurrently. The configuration of this program is composed of Reference Data, Data Inquiry, and Cost Assessment. The Reference Data includes characteristics of trees, monthly managements records, damage by blight and insects and usage of pesticides. The Data Inquiry includes an individual search of the tree index, simple searches and multiple searches. The Cost Assessment includes two main components, the data input with labor cost, manure ocst and pesticide cost and the assesment of management cost for prevention of blight and insects, pruning and fertilization. The results of this study are as follows: 1) When there are practices such as transplanting and removing of street trees it is immediately updated with the various situation. By creating an in progress a tree management system, up to the date information can be given to the manager for decision making. 2) To identify individual tree at the site or in drawing, the street name and numbers were used instead of coordinates. Tree tags are attached to the street trees individually. It can make DB management simple and easy. 3) By doing simple or multiple search with constructed DB, data can be provided quickly. 4) The result of this type of search are useful in the assessment of management cost very useful in regards to items such as the pruning, pesticides scattering and fertilization. 5) By using the AutoCAD software and existing PC without purchasing new equipment, the cost of system implementation can be minimized.

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Clinical considerations of use of titanium link - CAD/CAM zirconia abutment for dental implant in esthetically important areas (심미가 중요시되는 임플란트 치료시 타이타늄 링크-캐드캠 지르코니아 지대주 사용의 임상적 고려)

  • Kim, Jong-Yub
    • The Journal of the Korean dental association
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    • v.54 no.2
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    • pp.123-133
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    • 2016
  • Currently increasing use of implants, especially in anterior implant esthetics has become a major concern for both the patient and dentist. In the case of thin biotype if the thickness of the gingival soft tissue is less than 2mm, human eye can detect differences of colors depends on underlying materials. The zirconia abutment can be use not only for better esthetics but also for the hygienic because it is less attractive for the plaque deposition when it compare to the metals. Zirconia itself has many advantages as a biomaterial but also has frequent mechanical problems when it use for abutment of internal connection implant. For prevention or reduction of mechanical failures, use of titanium-link with zirconia super-structure which part that connects directly into the implant can be a good alternative. In this literature, I would like to review the clinical considerations of use of titanium link - CAD/CAM zirconia abutment for dental implant in esthetically important areas.

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Serum Fatty Acids in Patients with Angiographically-Documented Coronary Artery Disease (관상동맥질환자의 혈청 지방산 조성에 관한 연구)

  • 김수연
    • Journal of Nutrition and Health
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    • v.32 no.2
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    • pp.166-174
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    • 1999
  • To study the relation between serum fatty acids and coronary artery disease(CAD), 194 subjects were randomly selected and divided into three groups(control, single vessel disease group(SVD), muliple vessel disease group(MVD)) according to the angiographic results. Total serum levels of fatty acids and serum phospholipid(PL)-fatty acids(FAs)were analysed using gas chromatography and their associations with CAD were examined. Different patterns of total serum fatty acid levels were found in men and women. Levels of most fatty acids of SVD and MVD were significantly lower in men, while those of MVD were significantly higher in women. In terms of PL-FAs in both men and women, the levels of PL-FAs follow the order of control < SVD < MVD and in women, the difference was significant. Various ratio(including ratios denoting the activites of desaturase and elongase) of total serum-and PL-FAs were similar in the three groups. In the relation of serum fatty acids to serum lipid profiles, PUFA & LDL showed a negative correlation, while, SFA & LDL-cholesterol and PUFA and HDL-cholesterol showed positive correlatons. correlations. Systolic blood pressure and alcohol intake levels negatively affected the levels of serum LA, AA, EPA and DHA in the risk factor analysis. These findings are consistent with other evidence indicating that fatty acid compositions are changed in CAD, especially on the concentration base and the change was related to the severity of the disease. Therefore, for the purpose of disease prevention and therapeutic use, balanced intakes of various fatty acids must be seriously considered.

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Post-Traumatic Stress Disorder Symptoms and Quality of Life of Patients with Coronary Artery Disease (관상동맥질환자의 외상 후 스트레스장애 증상과 삶의 질)

  • Lee, Seung Ah;Kang, Jiyeon
    • Journal of Korean Critical Care Nursing
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    • v.12 no.1
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    • pp.82-93
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    • 2019
  • Purpose : The purpose of this study was to investigate the degree of post-traumatic stress disorder (PTSD) symptoms and the effect of PTSD on quality of life (QoL) among coronary artery disease (CAD) patients. Methods: The participants were 135 CAD patients who visited outpatient clinics in a university hospital in B city of Korea. Their PTSD symptoms and QoL were measured by structured questionnaires and analyzed with multiple hierarchical regression analysis. Results: Among the 135 participants, 20.7% were classified as moderate risk, and 3.7% as high risk for PTSD. PTSD symptoms were significantly higher in participants who were diagnosed with CAD within 6 months (t=26.02, p<.001). The physical component of health-related QoL was influenced by gender (${\beta}=-.25$, p =.003), recurrence of CAD (${\beta}=.21$, p =.008), and PTSD symptoms (${\beta}=-.33$, p <.001). The mental component of health-related QoL was influenced by religion (${\beta}=-.17$, p =.044), body mass index (${\beta}=.17$, p =.033), and PTSD symptoms (${\beta}=-.37$, p <.001). Conclusion: Patients who had had a CAD diagnosis for less than 6 months were found to be vulnerable to PTSD, and PTSD was found to have a negative impact on the physical and mental components of their QoL. It is necessary to develop an intervention program for the effective prevention and management of PTSD symptoms in patients with CAD.