• Clinical and Experimental Pediatrics
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• 제52권10호
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• pp.1175-1180
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• 2009

신생아 폐고혈압 지속증은 치료가 힘들고 사망률이 높은 질환이나, 산화질소 흡입 치료가 시행된 이후 사망률의 많은 감소를 가져왔다. 그러나, 신생아 집중 치료실이 있는 병원이라도 이러한 산화질소 흡입 치료가 가능하지 않는 곳이 많고, 산화질소 투여에도 호전되지 않는 경우도 있다. 흡입 iloprost는 최근 원발성 혹은 이차성 폐고혈압 환자에서 사용이 늘고있는 폐동맥 확장제로, 신생아 폐고혈압 지속증에 사용한 증례가 외국에 보고된 바 있다. 환아는 출생시 심한 태변 착색과 출산 질식, 진행되는 저산소증을 보였으며, 신생아 폐고혈압 지속증으로 진단되었다. 환아는 지속적인 저산소증을 보였으며, 통상적인 지지 치료에도 호전되지 않았다. 당시 저자들의 병원에는 산화질소 흡입 치료가 가능하지 않아, iloprost 흡입 치료를 시도하였다. Iloprost 흡입 치료 이후 수시간 내에 산소 포화도가 증가하였으며, 심초음파상에는 동맥관을 통한 우좌 단락이 좌우로 바뀌었고, 우심실 압력이 감소하였다. Iloprost 흡입 치료를 하는 동안 특별한 부작용은 관찰되지 않았다. 저자들은 산화질소 흡입치료가 가능하지 않은 상황에서 신생아 폐고혈압 지속증 신생아의 치료로 iloprost 흡입 치료를 시도한 경험을 보고하는 바이다.

• 한국안전학회지
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• 제35권4호
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• pp.84-91
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• 2020

The Korean nuclear industry developed the SPACE (Safety and Performance Analysis Code for nuclear power plants) code and this code adpots two-phase flows, two-fluid, three-field models which are comprised of gas, continuous liquid and droplet fields and has a capability to simulate three-dimensional model. According to the revised law by the Nuclear Safety and Security Commission (NSSC) in Korea, the multiple failure accidents that must be considered for accident management plan of nuclear power plant was determined based on the lessons learned from the Fukushima accident. Generally, to improve the reliability of the calculation results of a safety analysis code, verification work for separate and integral effect experiments is required. In this reason, the goal of this work is to verify calculation capability of SPACE code for multiple failure accident. For this purpose, it was selected the experiment which was conducted to simulate a Multiple Steam Generator Tube Rupture(MSGTR) accident with Passive Auxiliary Feedwater System(PAFS) operation by Korea Atomic Energy Research Institute (KAERI) and focused that the comparison between the experiment results and code calculation results to verify the performance of the SPACE code. The MSGR accident has a unique feature of the penetration of the barrier between the Reactor Coolant System (RCS) and the secondary system resulting from multiple failure of steam generator U-tubes. The PAFS is one of the advanced safety features with passive cooling system to replace a conventional active auxiliary feedwater system. This system is passively capable of condensing steam generated in steam generator and feeding the condensed water to the steam generator by gravity. As the results of overall system transient response using SPACE code showed similar trends with the experimental results such as the system pressure, mass flow rate, and collapsed water level in component. In conclusion, it could be concluded that the SPACE code has sufficient capability to simulate a MSGTR accident.

• 한국암반공학회:학술대회논문집
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• 한국암반공학회 2006년도 춘계학술발표회 논문집
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• pp.195-203
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• 2006

철도지하횡단공사는 횡단구조물 축조시 개착식과 비개착식 공법으로 구별되는데 개착식 공법은 열차의 비운행시간을 고려하여 시공하는 극히 제한적인 공법인데 반하여 비개착식은 열차의 속도 및 운행시간에 제약을 받지 않는 특징을 갖고 있으며 안전하고 신속한 시공의 장점을 갖고 있다. 비개착식 공법 중 Front Jacking 공법은 소구경의 강관을 압입하여 구조물과의 마찰력과 토압을 최소화시킨 후 현장에서 제작한 전단면 Precast Box 선단부에 PC강연선과 유압Jack을 이용하여 박스를 지중에 견인하는 공법으로 시공시 안정성과 열차의 정시성 확보가 유리하여 많이 적용되고 있다. 이 공법은 박스단면의 크기 및 연장, 지반조건에 관계없이 시공가능하며 친환경적인 시공을 할 수 있다. 본 고에서는 Front Jacking 공법이 적용된 대전동서관통대로의 철도횡단 시공사례를 소개하고자 한다.

• 한국임상수의학회지
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• 제31권4호
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• pp.350-353
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• 2014

A 13-year-old, castrated male, Shih Tzu dog with a history of acute ataxia was referred to veterinary medical teaching hospital and anesthetized for diagnostic magnetic resonance imaging of cervical intervertebral disk disease. After preanesthetic evaluation including physical examination, blood chemistry, radiography and ultrasound, the patient was premedicated with intravenous butorphanol (0.2 mg/kg). Anesthesia was induced by intravenous propofol (6 mg/kg) and maintained with isoflurane at 1.2 minimal alveolar concentrations. Because the mean arterial pressure (MAP) decreased from 70 to 58 mmHg at 70 minutes after induction, dobutamine was administered by constant rate infusion ($5{\mu}g/kg/min$) to treat hypotension. However MAP did not increase, and heart rate rapidly decreased from 100 to 55 beats per minute (bpm). To treat bradycardia, intravenous glycopyrrolate ($5{\mu}g/kg$) was administered, and heart rate increased to 165 bpm. After extubation of endotracheal tube, the patient showed normal recovery without any problems related to cardiovascular system. Unexpected dobutamine-induced bradycardia was considered as Bezold-Jarisch reflex. It is recommended that clinicians know and prepare the possibility of bradycardia during dobutamine therapy under general anesthesia.

• Bulletin of the Korean Chemical Society
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• 제32권8호
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• pp.2637-2642
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• 2011

A new ultrasonic-assisted micellar extraction and cloud-point pre-concentration method was developed for the determination of major saikosaponins, namely saikosaponins -A, -C and -D, in Radix Bupleuri by high performance liquid chromatography with evaporative light scattering detection (HPLC-ELSD). The non-ionic surfactant Genapol X-080 (oligoethylene glycol monoalkyl ether) was chosen as the extraction additive and parameters affecting the extraction efficiency were optimized. The highest yield was obtained with 10% (w/v) Genapol X-080, a liquid/solid ratio of 200:1 (mL/g) and ultrasonic-assisted extraction for 40 min. In addition, the optimum cloud-point pre-concentration was reached with 10% sodium sulfate and equilibration at $60^{\circ}C$ for 30 min. Separation was achieved on an Ascentis Express C18 column (100 ${\times}$ 4.6 mm i.d., 2.7 ${\mu}M$) using a binary mobile phase composed of 0.1% acetic acid and acetonitrile. Saikosaponins were detected by ELSD, which was operated at a $50^{\circ}C$ drift tube temperature and 3.0 bar nebulizer gas ($N_2$) pressure. The water-based solvent modified with Genapol X-080 showed better extraction efficiency compared to that of the conventional solvent methanol. Recovery of saikosaponins ranged from 93.1 to 101.9%. An environmentally-friendly extraction method was successfully applied to extract and enrich major saikosaponins in Radix Bupleuri.

• 한국세라믹학회지
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• 제36권9호
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• pp.937-945
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• 1999

반응결합 탄화규소(RBSC) 반응관을 보호하기 위하여, 반응결합 탄화규소 기판 위에 탄화규소를 1~10 범위의 입력기체비(${\alpha}=P_{H2}/P_{MTS}=Q_{H2}/Q_{MTS}$)와 1050~1300$^{\circ}C$범위의 증착온도에서 methyltrichlorosilane(MTS)로부터 수소분위기에서 저압화학기상법으로 증착하였다. 1250$^{\circ}C$의 증착온도에서 입력기체비가 감소함에 따라 증착속도는 증가하다가 감소하였다 입력기체비가 높을 때에는 (111) 우선배향성을 나타내고 과립형의 미세구조를 보이며, 입력기체비가 작을 경우에는 (220) 우선배향성을 가지는 마면주상의 미세구조가 관찰되었다. 증착온도가 증가함에 따라 입력기체비와 비슷하게 미세구조의 변화하는결과를 얻었으며, 이러한 결과는 증착기구의 변화와 밀접한 관련이 있다. 일정한 증착온도에서 입력기체비의 조정를 통하여 얻었으며, 이러한 결과는 증착기구의 변화와 밀접한 관련이 있다. 일정한 증착온도에서 입력기체비의 조절을 통하여 과립형과 미면주상의 미세구조를 함께 가지는 복층구조를 연속공정을 통하여 성공적으로 제조하였다.

• 대한기계학회논문집B
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• 제25권6호
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• pp.786-798
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• 2001

This paper describes the phenomena of wake-induced transition of the boundary layers on a NACA0012 airfoil using measured phase-averaged data. Especially, the phase-averaged wall shear stresses are reasonably evaluated using the principle of Computational Preston Tube Method. Due to the passing wake, the turbulent patch is generated in the laminar boundary layer on the airfoil and the boundary layer becomes temporarily transitional. The patches propagate downstream with less speed than free-stream velocity and merge with each other at further down stream station, and the boundary layer becomes more transitional. The generation of turbulent patch at the leading edge of the airfoil mainly depends on velocity defects and turbulent intensity profiles of passing wakes. However, the growth and merging of turbulent patches depend on local streamwise pressure gradients as well as characteristics of turbulent patches. In this transition process, the present experimental data show very similar features to the previous numerical and experimental studies. It is confirmed that the two phase-averaged mean velocity dips appear in the outer region of transitional boundary layer for each passing cycle. Relatively high values of the phase-averaged turbulent fluctuations in the outer region indicate the possibility that breakdown occurs in the outer layer not near the wall.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2005년도 춘계학술대회 논문집
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• pp.646-654
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• 2005

철도지하횡단공사는 횡단구조물 축조시 개착식과 비개착식 공법으로 구별되는데 개착식 공법은 열차의 비운행시간을 고려하여 시공하는 극히 제한적인 공법인데 반하여 비개착식은 열차의 속도 및 운행시간에 제약을 받지 않는 특징을 갖고 있으며 안전하고 신속한 시공의 장점을 갖고 있다. 비개착식 공법 중 Front Jacking 공법은 소구경의 강관을 압입하여 구조물과의 마찰력과 토압을 최소화 시킨 후 현장에서 제작한 전단면 Precast Box 선단부에 PC강연선과 유압Jack을 이용하여 박스를 지중에 견인하는 공법으로 시공시 안정성과 열차의 정시성 확보가 유리하여 많이 적용되고 있다. 이 공법은 박스단면의 크기 및 연장, 토질조건에 관계없이 시공가능하며 친환경적인 시공을 할 수 있다. 본 고에서는 Front Jacking 공법이 적용된 대전동서관통대로의 철도횡단 시공사례를 소개하고자 한다.

• 플랜트 저널
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• 제4권3호
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• pp.54-59
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• 2008

The resonance of boiler is caused by exciting force in the gas path and it generates the vibration by the harmony of boiler's dimensional factor. According to trending toward the boiler of increasing capacity and a bigger size, it has a problem of the vibration at back-pass heating surfaces. We can predict such vibrations as comparison between vortex frequency and gas column's natural frequency. We can't rely on the method for the past decades because of changing parameters, such as an allowable error, gas temperature, gas velocity, Strouhal number. We can reduce the vibration to use the seasoning effect and change the operating condition in coal fired boiler but it's not essential solution. When the vibration occurred in the model boiler, we must measures the acoustic pressure and frequency of places for considering the means. So far, we confirmed the problem from field measures and theoretical analysis about the acoustic vibration of boiler. We installed anti-acoustic baffle in a existing boiler to change the acoustic natural frequency at the cavity, which results in reducing the acoustic vibration. The first, we prove that the acoustic resonance is caused by harmonizing vortex shedding frequency of tube heat surface with acoustic natural frequency of cavity in the range of 650~750 MW loads. The second, the acoustic resonance at the back-pass heating surface has the third order of acoustic natural frequency at the second economizer. We install five anti-acoustic baffles at the second economizer to reducing the resonance. We confirm considerably reducing the acoustic vibration of boiler during the commercial boiler.

• 동력기계공학회지
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• 제21권2호
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• pp.64-69
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• 2017

The purpose of this study is to investigate the performance characteristics of seawater cooling system for a fishing vessel. The circulation amount of refrigerant, condensation capacity, evaporation capacity, compression work and coefficient of performance(COP) were analyzed as the heat source temperature changed. The experimental setup consisted of an open-type compressor, a shell&tube type condenser, an evaporator and an expansion valve. The heat source was controlled by a constant temperature chamber. The main results of this study are summarized as follows. The condensation capacity increased with increasing heat source temperature, and it was confirmed that the effect of circulating amount of refrigerant was dominant. The amount of heat for vaporization was almost constant even though the temperature of the heat source increased. On the other hand, the compression power was increased. This is because the compression ratio increases as the condensation pressure, the enthalpy difference between inlet and outlet, the amount of circulating refrigerant increases. The performance coefficient of this system showed a tendency decreasing with increasing heat source temperature. Therefore, the basic data of the seawater cooling system for the maintenance of the catch line of the shore fishing boats was acquired through this study, and it is considered that it will be sufficient for the actual design.