• The Korean Journal of Physiology
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• 제17권2호
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• pp.93-101
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• 1983

국소한냉자극이 전신 및 국소혈액순환에 미치는 영향과 동계에 있어서 한냉에 대한 적응을 관찰하기 위하여 동계 및 하계에 편균연령 21세의 남녀 대학생 각 60명 및 50명을 대상으로 $5^{\circ}C$의 냉수에 일측 손을 담구어 3분간 국소한냉자극을 가하였다. 침수 1, 2, 3분과 회복기 1, 3, 5분에 침수한 측과 침수 반대측에서 평균혈압, 분시심박수, 광전 모세혈관 맥박의 파고, 피부전기저항을 관찰하여 다음과 같은 결과를 얻었다. 국소한냉자극시 혈압은 증가하였고 하계에서 동계보다 더 큰 증가를 보였다. 회복기에 동계는 서서히 대조치로 회복되나 하계에는 대조치보다 유의하게 감소하였다. 분시심박수는 침수시 증가하며 하계에서 동계보다 더 증가하였고 회복기에는 동계 및 하계 모두 대조치보다 감소하였다. 광전 모세혈관 맥박의 파고는 동계에는 침수 및 침수 반대측 모두 감소하였으나 침수한 측에서 더 크게 감소하였으며 이는 침수한 측에 있어서 한냉의 국소효과에 기인한 것으로 보인다. 하계에는 동계보다 작은 감소를 보였으며 회복기에는 더 빠른 회복을 보여 대조치보다 증가하였다. 피부전기저항은 침수시 침수 반대측에서는 감소하나 침수한 측에서는 유의하게 증가하였다가 회복기에 서서히 감소하였다. 침수 반대측의 감소는 동통에 의한 반응이 한냉에 의한 반응에 첨가되어 나타난 것으로 보이며, 침수한 측은 한냉에 의한 국소효과가 크기 때문인 것으로 보인다. 이상으로 $5^{\circ}C$의 국소한냉자극시 전신적 반응은 한냉자극에 의한 동통성 stress에 기인한 반응이 우세한 것으로 생각되며 김 등$^{39)}$의 보고와는 달리 동계 및 하계의 반응의 차이는 계절에 따른 한냉자극에 대한 주관적 감각의 차이에 의한 것으로 동계에서 한냉기후에 의한 국소한냉자극의 적응현상은 나타나지 않는 것으로 사료된다.

• 한방재활의학과학회지
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• 제33권4호
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• pp.167-184
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• 2023

Objectives This study was designed to assess the effectiveness of ultrasound therapy at the ST11 for regulation of sympathetic hyperactivity. Methods Forty healthy adult subjects were assigned to experimental group and control group. After taking mental stress, ultrasound therapy was applied at the ST11 in experimental group and sham-ultrasound therapy was applied in control group. The evaluation of sympathetic activity was measured by blood pressure, pulse rate, and heart rate variability at 3 times (Time 1: before the stress stimulation, Time 2: after the stress stimulation, Time 3: after the intervention). The primary end point was consisted of normalized (norm) low frequency (LF)/high frequency (HF) ratio, LF (norm), HF (norm). The secondary end point was consisted of systolic blood pressure, diastolic blood pressure, pulse rate, mean heart rate, standard deviation of NN intervals, root mean square of the successive differences, total power (log). Results After the stress stimulation, all subjects showed sympathetic hyperactivity. After the intervention, the experimental group showed lower sympathetic activity than the control group. Comparing the Time 3 and Time 1, the experimental group showed no significantly differences in sympathetic activity while the control group showed higher sympathetic activity in Time 3 than Time 1. Comparing the Time 3 and Time 2, the experimental group showed lower sympathetic activity in Time 3 than Time 2 while the control group showed higher sympathetic activity in Time 3 than Time 2. Conclusions We suggest that the ultrasound therapy at ST11 can decrease sympathetic activity in sympathetic hyperactivity condition.

• 대한한방내과학회지
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• 제39권3호
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• pp.426-442
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• 2018

Objective: This study aimed to compare the effects of Zusanli and nonacupoint electroacupuncture stimulation on ultrasonographic gastric emptying and vital signs in eight healthy participants. Gastric emptying and its rate of change were analyzed to search for correlation with physical characteristics such as body mass index (BMI), sternocostal angle, and abdominal wall thickness. Methods: Eight healthy participants with no gastrointestinal disorders were enrolled in this study. Each participant went through three abdominal sonographies for gastric emptying assessment. At the second and third visits, participants received Zusanli and nonacupoint electroacupuncture stimulation in a random order. During the study period, we examined the BMI, sternocostal angle, and abdominal wall thickness of all participants. Vital signs (blood pressure, heart rate, and temperature) were also examined before and after the electroacupuncture stimulation. Results: Electroacupuncture stimulation at Zusanli significantly improved gastric emptying when compared to nonacupoint stimulation. Gastric emptying showed a positive correlation with BMI, sternocostal angle, and abdominal wall thickness, but this correlation was statistically insignificant. The improvement rate of gastric emptying by Zusanli electroacupuncture stimulation showed a positive correlation with BMI and sternocostal angle and a negative correlation with abdominal wall thickness. However, such results were also statistically insignificant. Among vital signs, only heart rate showed a significant decrease according to Zusanli electroacupuncture stimulation. Conclusions: A significant effect of Zusanli electroacupuncture was confirmed through ultrasonographic gastric emptying in healthy participants.

• 대한물리치료과학회지
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• 제10권1호
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• pp.158-169
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• 2003

The present study examined that in vivo test is investigated in sham-operated(control group) and aldosterone-analogue deoxycorticosterone acetate (DOCA)-salt hypertensive animals(experimental group) and that the antihypertensive effect was induced by silver spike point(SSP) low frequency electrical stimulation at meridian points(CV-3, -4, Ki-12, SP-6, LR-3, BL-25, -28, -32, -52), specifically, such as diuretic action in 24 hour urine analysis from normal volunteer. The $Na^+$ and $Ca^{2+}$ ions were significantly increased in aldosterone-analogue DOCA-salt hypertensive rats than that in sham-operated rats. However, the $K^+$ ions were significantly decreased in aldosterone-analogue DOCA-salt hypertensive rats than that in sham-operated rats. The current of 1 Hz continue type of SSP low frequency electrical stimulation significantly increased in excretion of urine $Na^+$ and $K^+$ ions from normal volunteer. However, the excretion of $Ca^{2+}$ ion were significantly decreased by SSP electrical stimulation in volunteer. These results suggest that the development of aldosterone analogue-DOCA-salt hypertension is associated with changed $Na^+$, $K^+$ and $Ca^{2+}$ ions of urine. which directly affects blood pressure. Therefore, the hypertension is a risk factor on cardiovascular disease. Moreover, These results demonstrate that the SSP low frequency electrical stimulation, especially current of 1 Hz continue type, significantly regulates $Na^+$, $Ca^{2+}$ and $K^+$ ions from volunteer. Therefore, the SSP low frequency electrical stimulation is a good regulator through a diuretic action of aldosterone-induced hypertension.

• The Korean Journal of Physiology
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• 제27권1호
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• pp.37-49
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• 1993

Ventilatory responses to inhaled $CO_2$ were measured during continuous negative pressure breathing (CNPB) in awake dogs. End expiratory lung volume (EELV) decreased linearly with pressure level during CNPB (correlation coefficient= 0.81, p<0.005) during air breathing. When CNPB was applied during 5% $CO_2$ inhalation, the decrease in EELV was not significantly different (p<0.5) from that during air breathing. As a result of a lowered EELV, tidal volume ($V_T$) significantly decreased by 22% and breathing frequency ($f_B$) increased by 68% in the steady state during air breathing (p<0.0001). These responses were similar during 5% $CO_2$ inhalation, thus the $CO_2$ response curve measured during CNPB shifted upward without a change in sensitivity (p>0.05). These results indicate additive effects of CNPB and $CO_2$ inhalation. The degree of hyperventilation during CNPB at eupnea was estimated to be 63% of that during control ventilation and was significantly greater than zero (p<0.0001), which suggests an alveolar hyperventilation due to CNPB. These results suggest that the mechanical alterations associated with n decrease in lung volume could play an important role in ventilatory control independently of chemical regulation of breathing. Thus, exercise hyperpnea, which is associated with a lowered functional residual capacity (FRC), may in part be explained by this mechanical stimulation of breathing.

• 한국전문물리치료학회지
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• 제2권2호
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• pp.85-97
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• 1995

When applying FES to patients, proper evaluation must be performed prior to treating patient. Patients with thoracic lesions between $T_4{\sim}T_{12}$ are suitable for FES. However, these patients must have excitability of the leg muscles. Thus, excitability testing is an essential part of the screening program(stimulation at 80V gives a response). Before standing or walking is attempted the patients must perform restrengthening exercise, so that the Quadriceps muscle group minimum strength is 40 Nm (corresponding to a manual grade of F+ to G). After that walking and standing can be attempted. The effects of FES are as follows: prevents pressure sores; development and maintenance of muscle properties; prevents disuse atrophy and contractures.

• 대한약리학회지
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• 제18권1호
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• pp.23-31
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• 1982

1) 카드뮴(Cd) 중독가토(中毒家兎)의 전신동맥혈압(全身動脈血壓) 및 이곡혈관(耳穀血管)의 말초저항(末梢抵抗)은 비(非)중독 대조군에 비(比)하여 증가(增加)되었다. 2) Cd중독군 혈관의 전기자극 반응은 대조군혈관의 것에 비(比)하여 현저히 감약되어 있었다. 그러나 norepinephrine에 대(對)하여는 전자(前者)에서 super-sensitivity를 나타내었다. 3) Arachidonate에 의하여 전기자극반응이 대조군혈관에서는 억제되었으나 Cd중독군에서는 증가되었다. 그리고 $PGE_2$ 및 $PGF_{2{\alpha}}$에 의하여는 양군혈관 모두 반응이 억제되었다. 4. Indomethacin전처치 혈관은 대조군에서는 영향을 받지 않았으나 Cd중독군은 월등히 증가되었다. 5) 비(非)중독군 혈관을 PSS로 관류시는 전기자극반응이 영향을 받지 아니하였으나 $K^+-free\;PSS$로 바꾸었을 때는 항진되었고 norepinephrine 반응은 변화가 없었다. 이상의 결과(結果)로 Cd중독시 동맥압의 상승과 말초저항의 증가는 혈관운동의 조절기전에 변동이 초래되어 야기되었다고 생각한다.

• 한국정밀공학회지
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• 제32권10호
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• pp.845-850
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• 2015

This study was designed to investigate the feasibility of utilizing an adaptation for selective elicitation of tactile sensations by means of transcutaneous electrical stimulation. We conducted the first experiment to investigate how the stimulation frequency affected the adaptation. Twenty healthy subjects participated in the second experiment to confirm our proposal that the perception intensity of the low-frequency vibration can be enhanced after a high-frequency adaptation, and vice versa. It was found that (1) a low-frequency stimulation did not adapt the nerve afferents responsible for the high-frequency vibration, (2) a high-frequency stimulation affected the nerve afferents responsible for the low-frequency vibration, but adapted to the pressure sensation more intensely, and (3) more than 62% of the subjects reported a more clear selective sensation after the adaptation had lessened or depressed the unwanted sensation. The observations showed that adaptation of the nerve afferent could be utilized for selective elicitation of tactile sensations.

• The Journal of Korean Physical Therapy
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• 제25권3호
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• pp.136-142
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• 2013

Purpose: The application of transcutaneous electrical nerve stimulation (TENS) is beneficial for joint movements, inhibition of spasticity, and the improvement of walking ability in patients with chronic hemiplegia. This study aimed to identify the effect of the application of TENS to the knee extensor on the affected side with respect to postural-sway distance and velocity during the sit-to stand movement. Methods: We included 19 patients with post-stroke hemiplegia in this study. They underwent measurements during the sit-to stand movement on a force plate with 5 different stimulation dosages applied over 7 s:No TENS, high-frequency and high intensity TENS, high-frequency and low intensity TENS, low-frequency and high intensity TENS, and low-frequency and low intensity TENS The 5 different condition were administered in random order. Results: The group that received TENS application exhibited a significant decrease in path length and average velocity of center of pressure (COP) displacement compared with the group that did not receive TENS application. TENS dosage at low frequency (3Hz) and high intensity yielded a significant decrease in path length, average velocity, mediolateral distance and anteroposterior distance of COP displacement (p<0.05). Conclusion: Our results demonstrated the effectiveness of the application of low-frequency TENS on STS performance. These findings provide useful information on the application of TENS for the reduction of postural sway during the sit-to-stand movement after stroke.

• 대한의용생체공학회:의공학회지
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• 제31권3호
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• pp.210-216
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• 2010

This study is vestibular electric stimulation applied between the mastoids during quiet standing elicits postural sway. The aim of this study was to characterize the postural sway response to continuous sinusoidal vestibular electric stimulation across various stimulus frequencies and amplitudes. Binaural bipolar sinusoidal vestibular electric stimulation was applied to the skin overlying the mastoid processes of 10 subjects while they stood on a force plate. The position of the center of pressure(COP) and signals at the feet are obtained on an force plate, while the head and whole body center of mass(COM) was measured with motion analysis system. The stimulus conditions included eight frequencies (1/64, 1/32, 1/16, 1/8, 1/4, 1/2, 1, and 2Hz) and six peak amplitudes (0.1, 0.25, 0.5, 0.7, 1 and 2mA). Each subject experienced one trial at each amplitude-frequency pair. The stimuli elicited sway in lateral plane in all subjects, as evidenced by changes in the stimulus frequency. Our results demonstrate that the vestibular system is sensitive to vestibular electric stimulation intensity changes and responds by altering the magnitude of the response accordingly.