• Journal of Preventive Medicine and Public Health
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• v.29 no.1 s.52
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• pp.43-50
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• 1996

We experienced a case of nephropathy in chronic lead poisoning. The patient was 43-year-old male who has been working in secondary lead smelting plant for 14 years. On admission, blood pressure was 160/90 mmHg and the others were non-specific. In past history, he received chelating agent administration for lead poisoning irregularly and medicated for gout, and the blood lead concentration was $180.0{\mu}g/dl$ on 2 months before admission. Smoking habit has been 1 pack per day for 15 years and drinking habit has been 1 bottle of Soju per day but less flow. In liver function test, AST/ALT were 27/28 IU/l and $\gamma-GT$ was 456 IU/l. In blood test, Hb : 11.5 g/dl, Hct : 34.0% and basophilic stipplings were found in peripheral blood smear. Chest PA was normal and abdominal ultrasonographic finding was non-specific except fatty liver. In the test of lead exposure indices, $PbB:83.0{\mu}g/dl,\;PbU:28.3{\mu}g/l$, and blood ZPP was $300.0{\mu}g/dl$. And in renal function test, BUN : 31.4 mg/dl, blood creatinine : 2.7mg/dl, blood uric acid. 9.1 mg/dl, urinary albumin : 100.0 mg/g creatinine, urinary $\alpha_1-microglobulin$ : 120.5 mg/g creatinine, urinary $\beta_2-microglobulin$ : $183.8{\mu}g/g$ creatinine, and 24 hours urinary creatinine clearance was 31.9 ml/min. The ultrasonoguided renal biopsy showed the global sclerosis of glomerulus, moderate atrophy and loss of tubule, and interstitial fibrosis in light microscopy. There were diffuse losses of brush border of proximal tubule in electronmicroscopy.

• Korean Journal of Community Nutrition
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• v.21 no.4
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• pp.378-385
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• 2016

Objectives: This study was conducted to investigate the association between sarcopenia and sarcopenic obesity and cardiovascular disease risk in Korean postmenopausal women. Methods: We analyzed data of 2,019 postmenopausal women aged 50-64 years who participated in the Korea National Health and Nutrition Examination Survey in 2008-2011 and were free of cardiovascular disease history. Blood pressure, height, and weight were measured. We analyzed the serum concentrations of glucose, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglyceride levels. Waist circumference was used to measure obesity. Appendicular skeletal muscle mass was measured by dual-energy X-ray absorptiometry. Sarcopenia was defined as the appendicular skeletal muscle mass/body weight<1 standard deviation below the gender-specific means for healthy young adults. The estimated 10-year risk of cardiovascular disease risk was calculated by Pooled Cohort Equation. Subjects were classified as non-sarcopenia, sarcopenia, or sarcopenic obesity based on status of waist circumference and appendicular skeletal muscle mass. Results: The prevalence of sarcopenia and sarcopenic obesity was 16.3% (n=317) and 18.3% (n=369), respectively. The 10-year risk of cardiovascular disease risk in the sarcopenic obesity group was higher ($3.82{\pm}0.22%$) than the normal group ($2.73{\pm}0.09%$) and sarcopenia group ($3.17{\pm}0.22%$) (p < 0.000). The odd ratios (ORs) for the ${\geq}7.5%$ 10-year risk of cardiovascular disease risk were significantly higher in the sarcopenic obesity group (OR 3.609, 95% CI: 2.030-6.417) compared to the sarcopenia group (OR 2.799, 95% CI: 1.463-5.352) (p for trend < 0.000) after adjusting for independent variables (i.e., exercise, period of menopausal, alcohol use disorders identification test (AUDIT) score, income, education level, calorie intake, %fat intake and hormonal replacement therapy). Conclusions: Sarcopenia and sarcopenic obesity appear to be associated with higher risk factors predicting the 10-year risks of cardiovascular disease risk in postmenopausal women. These findings imply that maintaining normal weight and muscle mass may be important for cardiovascular disease risk prevention in postmenopausal women.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.4
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• pp.273-283
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• 2020

Numerical simulations of the storm surge and waves induced by the Typhoon Bolaven incident on the west sea of Korea in 2012 are performed using the JMA-MSM weather field provided by the Japan Meteorological Agency, and the calculated surge heights are compared with the time history observed at harbours along the various coasts of Korea. For the waves occurring coincidentally with the storm surges the calculated significant wave heights are compared with the data measured using the wave buoys operated by the Korea Hydrographic and Oceanographic Agency and the Korea Meteorological Administration. Additional simulations are also performed based on the pressure and wind fields obtained using the best track information provided by the Joint Typhoon Warning Center, and the calculated results are compared and analyzed. The waves and storm surges calculated using JMA-MSM wether field agree well with the observations because of the better reflection of the topography and the pre-background weather field. On the other hand, the calculated results based on the weather fields produced using the JTWC best track information show some limitations of the general trend of the variations of wave and surge heights. Based on the results of this study it is found that the reliable weather fields are essential for the accurate simulation of storm surges and waves.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.5
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• pp.351-362
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• 2020

Numerical simulations of the storm surge and waves induced by the Typhoon Maemi incident on the south sea of Korea in 2003 are performed using the JMA-MSM forecast weather field, NCEP-CFSR reanalysis weather field, ECMWF-ERA5 reanalysis weather field, and the pressure and wind fields obtained using the best track information provided by JTWC. The calculated surge heights are compared with the time history observed at harbours along the coasts of Korea. For the waves occurring coincidentally with the storm surges the calculated significant wave heights are compared with the measured data. Based on the comparison of surge and wave heights the assessment of the reliability of various weather fields is performed. As a result the JMA-MSM weather fields gives the highest reliability, and the weather field obtained using JTWC best track information gives also relatively good agreement. The ECMWF-ERA5 gives in general surge and wave heights weaker than the measured. The reliability of NCEP-CFSR turns out to be the worst for this special case of Typhoon Maemi. Based on the results of this study it is found that the reliable weather fields are essential for the accurate simulation of storm surges and waves.

• Journal of The Korean Society of Clinical Toxicology
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• v.7 no.2
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• pp.137-142
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• 2009

Purpose: This study was conducted to investigate the characteristics of drug induced anaphylactis and anaphylactic shock in patients who were admitted to the emergency department Methods: We retrospectively collected the data on patients with drug induced anaphylaxis and who were admitted to the emergency department from January 2001 to June 2009. The study group was divided into the non-shock and shock groups according to whether the systolic blood pressure more than 90mmHg. The initial demographic data, the causes of drug-induced anaphylaxis, the clinical manifestations, the treatment and the prognosis were reviewed for 72 patients. Results: The mean age of the study subjects was $47.9P{\pm}14.2$ years old and there were 40 male patients and 32 female patients. There were 26 patients in the non-shock group and 46 in the shock group. The mean age was older in the shock group than in the non-shock group ($51.5{\pm}15.1$ vs $42.5{\pm}10.6$, p-0.002). A history of drug allergy was more common in the shock group, but no difference was found for the comorbid chronic diseases between the two groups. Radio-contrast media was the most common cause, followed non-steroidal anti inflammatory drugs and antibiotics, but there is no difference in the causes between the two groups. The symptoms of cyanosis, syncope, sweating and dizziness were more frequently manifested in the shock group. The administration of intravenous fluid and injection of subcutaneous epinephrine at the emergency department were more frequent in the shock group than in the non-shock group. Conclusion: For the patients who were admitted to the emergency department with drug induced anaphylaxis, the mean age was older and the symptoms of cyanosis, syncope, sweating, dizziness were more frequent in the anaphylactic shock patients than in the non-shock group. More treatments were given at the emergency department to the anaphylactic shock patients.

• Journal of the Korean Applied Science and Technology
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• v.37 no.3
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• pp.509-515
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• 2020

The purpose of this study was to analyze the correlation between passive ankle movement range and knee joint kinetic variables during squat movement. In this study, a total of 27 subjects participated in this study, 19 men and 8 women, who had no history of the musculoskeletal system of the lower extremity. To verify the correlation between the ankle joint flexibility and the knee joint kinetic variables during deep squat, it was performed pearson's correlation coefficient and variables showing statistically significant correlation were performed by simple regression analysis at a significant level of α .05. Through this study, the relationship between the peak joint moment and joint reaction force factors that determine ankle joint flexibility and knee joint pressure was confirmed. Therefore, when applying an exercise that can generate a lot of load on the knee joint such as deep squats during strength training, checking the degree of flexibility of the ankle joint among physical characteristics to the individual may reduce the stability of the body and the risk of injury to the knee joint. It is expected to be helpful in setting the intensity of exercise that can be done.

• Journal of Acupuncture Research
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• v.22 no.3
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• pp.145-153
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• 2005

Objective : This study was designed to investigate the effects and adverse effects of Choweseuncheng-tang on obesity patients Methods : Choweseuncheng-tang was given to 20 obesity patients who have no abnormality of GOT, GPT and past medical history. Additionally, electroacupuncture was performed on Fuchao(腑巢) with 60Hz. We compared body weight, body fat and laboratoy test(GOT, GPT, BUN, Creatinine) between before and after treatment. Blood pressure, heart rate and clinical symptoms were checked to investigate the side effects. Decrease of body weight was checked in accordance with Sasang constitutional type, appetite type, and BMI. Results : 6 patients(BMI 23-24.9), 10 patiets(BMI 25-29.9), and 4 patients(BMI over 30) were showed decrease of body weight. We found body fat was decerased $3.16{\pm}1.25%$. BUN, Creatinine, GOT and GPT were increased within normal range. There were adverse event of autonomic hyperactivity(11 patients), gastrointestinal symptoms(7 patients) and others(3 patients). Conclusions : According to above results, Choweseuncheng-tang could be used effectively, but should be taken cautiously on obese patients.

• Sleep Medicine and Psychophysiology
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• v.14 no.1
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• pp.49-53
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• 2007

Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered breathing become a clue of diagnosis for mitochondrial myopathy. We report a case of a 21 year-old man who was diagnosed as mitochondrial myopathy during the investigation for the possible cause of chronic hypoventilation syndrome. Before being admitted to our hospital, he was suspected as having sleep apnea syndrome in another hospital. We re-evaluated the history, physical examination, laboratoy findings and polysomnography in detail. Severe hypoxemia was noted during REM sleep on nocturnal polysomnography and the diagnosis of mitochondrial myopathy was made by muscle biopsy in rectus abdominis muscle. We treated him with bilevel positive airway pressure therapy during sleep and it could reverse the hypoxemia during REM sleep. He could be discharged with improved condition and is being well with the use of this ventilatory assistance.

• Korean Journal of Health Education and Promotion
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• v.17 no.2
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• pp.17-33
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• 2000

The aim of this study is having the status, knowledge and attitude of the high school attendees toward smoking be analyzed, helping to make effective health education methods to diminish adolescent smoking habits. The field self-questionnaire investigation has been performed from Oct 10th through 23rd in 1999. The whole 427 cases were distributed to 1st and 2nd grade students of randomly selected men's high school in Seoul. And 414 cases (97%) were finally selected for analysis after exclusion of cases with insufficient information. The main contents of questionnaire are composed of several sectors; the general characteristics of the interviewees, the relationship with parents, the life style and the peer relationship in school. And smoking-related characteristics are taken into consideration, too. The major findings of the study are as follows: The smoking/non-smoking related factors are, in socio-demographical terms, the grade, average spending per month of the interviewees. And the degree of satisfactory relationship with parents is significant on smoking behavior. The higher, the degree of satisfaction on school life and relationship with designated teacher, the more chances of non-smoking habit. Poor academic grades and peer group dependability of interviewees cause higher smoking habit rate in other way. The self-interviewees grade and cohabitation with parents are also significant on both the attitude toward smoking habit and the knowledge on smoking statistically. The academic history and vocations of the parents and the academic grades of interviewees are also effective variables, but don't make any gap between groups knowledge on smoking. Smoking groups used to have positive attitude toward smoking habit. Both the attitude and knowledge on smoking by the consideration of Quit-smoking have statistically significance. The groups which have negative attitude and high knowledge on smoking quit-smoking into consideration. And the primary cause of quit-smoking is on health by smoking. Depression, stress, adult smoking in the house, peer group pressure, cigarettes advertisements on papers and magazines and smoking scenes on TV have positive correlation on forming smoking habit (p〈0.001) But the knowledge on diseases triggered by smoking has negative correlation on forming smoking habit. (p〈0.05, p〈0.001). Social factors as monthly spending, relationship and communication with parents, the degree of satisfaction in school life, academic grades and student-teacher relationship have crucial negative correlation on smoking habit. That is to say, the higher, the monthly spending is, the worse, the relationship with parents and teachers is, the lower, the academic grades of the student is, the percentage of the interviewees who have smoking habit seems to get higher.

• Journal of Preventive Medicine and Public Health
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• v.40 no.4
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• pp.305-312
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• 2007

Objectives : To estimate the awareness, treatment and control rate, as well as to identify the awareness-related factors for hypertension. Methods : The study participants were 482 adults (men 206, women 276), aged 45 or over, diagnosed with hypertension and living in Chuncheon. The awareness rate was defined as the proportion of persons among those with hypertension who had previously been diagnosed by a physician. The treatment rate was defined as the proportion of persons who had used anti-hypertensive medication, among those who were aware of their hypertension. The control rate was defined as the proportion of persons who kept blood pressure normal, among those who had been treated for their hypertension. Multivariable logistic regression analysis was carried out for the awareness-related factors using SAS VER 8.1. Results : The awareness, treatment, and control rate were 55,8% (53.4% for men; 57.6% for women), 89.6% (87,2% for men; 91.2% for women), and 34.4% (28.1 % for men; 38.6% for women), respectively. The awareness-related factors included a family history of hypertension (odds ratio[OR], 5.63; 95% confidence interval[95% CI]=1.53-20.72), smoking([Ex; OR 0.38, 95% CI= 0.15-0.96)], [Current; OR 0.28, 95% CI=0.10-0.80]), and alcohol intake ([Ex; OR 3.22, 95% CI 1.03-10.09],[Current; OR 3.36, 95% CI=1.30-8.71]) for men, and education(OR 2.23, 95% CI=1.10-4.53), body mass index(OR 2.72, 95% CI=1.13-6.53), and self-rated health(OR 2.38, 95% CI=1.07-5.30) for women. Conclusions : The awareness rate of hypertension among the middle aged and elderly in Chuncheon was 55.8%. The related factors of awareness were gender specific. Further studies are needed to elucidate the putative reasons for these gender differences.