• 비파괴검사학회지
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• 제19권5호
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• pp.356-362
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• 1999

공업용 방사선 필름의 필름 농도가 대략 3.5 이하의 농도 구간에서 상대 노출에 대해 지수 함수적으로 증가한다고 가정하여, 필름특성곡선에 관한 일반식과 두께 변화에 대한 농도 변화 관계식을 새로이 제안하였다. 연속 X-선과 $Ir^{192}$에 의한 ${\gamma}$-선으로 탄소강의 계단시편에 대해 시험한 결과, 대략 $1.0{\sim}3.5$의 농도 범위에서 두께 변화에 대한 농도의 상용 대수변화가 기존의 관계식에 비해 보다 선형적인 경향을 나타내었으며 실제 계단 시편의 치수와 제안한 관계식에 의한 평가를 비교한 결과 본 연구에서 제안한 농도-두께 관계식에 의한 결과가 기존의 관계식에 의한 결과보다 정확하였다. 그리고 시험체의 두께가 증가함에 따라 beam hardening effect에 의해 유효선흡수계수가 달라지는 연속 X-선에 비해 상대적으로 에너지 스펙트럼이 단순한 ${\gamma}$-선이 두께 평가를 위한 더 적합한 방사선원임을 확인하였다. 본 연구에서 제안한 관계식은 국부적인 부식 손상의 깊이와 분포도를 평가할 수 있으므로 압력 용기 등의 산업 설비의 건전성 평가에 활용할 수 있다.

• 대한소아치과학회지
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• 제33권3호
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• pp.522-528
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• 2006

치아가 치조골 내에서 변위 시 치근단부 혈관이 압박, 파열될 수 있으며, 치수의 반응은 치근 발육정도, 치아 함입정도, 치수 감염정도에 따라 영향을 받게 된다. 치수생활력 상실 시 치수치료가 필요하므로 외상 후 정기 검진을 통해 치수 생활력 검사를 주기적으로 시행해야 하며, 치관에서 나타나는 색조 변화 및 방사선 사진 상 치근의 흡수 유무를 관찰해야 한다. 탈구성 손상 후 치수 괴사 치근관 폐쇄, 치근 외흡수, 치근 유착 그리고 주변골 상실 등이 나타날 수 있다. 치수생활력 검사 시, 양성 반응에서 시간 경과 후에 음성 반응을 보이는 경우는 치수 괴사를 의심해야 하며 가능한 한 치근 흡수가 일어나기 전에 치수 치료를 시행하는 것이 바람직하다. 이에 본 두 증례에서 나타난 결과를 비교하여 함입 후의 합병증과 이를 야기하는 인자에 대해 확인할 수 있었기에 보고하는 바이다.

• 대한간호학회지
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• 제27권2호
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• pp.433-443
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• 1997

Cardiac catheterization is a diagnostic procedure which is intrusive and anxiety provoking. Patient education and information offer have been suggested as effective nursing interventions to reduce patients' anxiety and stress. Main objectives of this study are : 1) to develop concrete objective information for patients undergoing cardiac catheterization : 2) to analyze the types of information included in the newly developed concrete objective information. The subjects of this study are 11 patients who were admitted to the CCU of a general hospital in Seoul. The subjects were provided with preparatory information about cardiac catheterization by using interview and a booklet. After the procedure, the subjects were asked to describe additional information which they suggest to be added into the booklet and the physical sensations felt during the procedure. The results of the study are summarized as follows : Most subjects were satisfied with the preparatory information that was provided by interview and the booklet before the procedure. But patients suggested several problems related to the content of the booklet. First, they reported difficulty to differentiate the terms -coronary angio gram and cardiac catheterization. Also, some patients expressed that they feared after reading the information about the incision of inguinal area. Subjects responded that the information about the direct process of the test did not reduce their anxiety and the information was not detail enough. Next, most subjects would want to know about the monitor and the sound from monitor. They said that they could not hear instructions from doctor or nurse during the procedure due to tension. Considering above response results, the need for more effective way to provide information, like visual and auditory information through video tape for giving information is suggested. Sensations related to the procedure were the smell coming from sterilization of inguinal area, stinging pain in groin when the doctor inserts a needle into artery, and the sensation of pressure and moving of vessels surrounding neck when the catheter was inserted and visualized on fluoroscopy. Besides, subject reported hot sensation and burning feeling in face and chest area, and nausea when dye is injected by hand. In the analysis of information content, there was 79% agreement on the actual units of analysis that were coded. In the analysis of type of information, procedural information was 60.4%. Concrete objective information was 28.1%. and other information was 11.5%. Agreement of the coders in categorizing the units of information was determined by using Cohen's kappa which corrects for chance agreement. Cohen's kappa was .84.

• Journal of Advanced Marine Engineering and Technology
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• 제38권6호
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• pp.681-687
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• 2014

본 논문에서는 해군함정의 추진용 디젤엔진의 연료로 사용되는 선박용 디젤연료와 바이오디젤을 단기통 엔진에 적용시켜 연료분사시기에 따른 실린더 내 연소특성, 엔진성능 및 질소산화물 배출 특성을 분석하고, 초고속 카메라를 이용하여 선박용 디젤연료와 바이오디젤연료의 연소과정을 분석하는데 초점을 두었다. 연료분사시기가 $BTDC25^{\circ}CA$에서 $BTDC5^{\circ}CA$까지 지각될수록 실린대 내 연소최고압력은 점점 떨어졌으나, 토크는 증가하는 경향을 보였다. 질소산화물은 $BTDC15^{\circ}CA$에서 가장 높게 측정되었으며, $BTDC15^{\circ}CA$를 기준으로 지각 및 진각조건에서는 저감되는 것으로 분석되었다. 연료분사시기가 $BTDC5^{\circ}CA$일 때 선박용 디젤연료와 바이오디젤연료의 연소과정을 비교한 결과 산소가 포함된 바이오디젤연료의 착화시기가 선박용 디젤연료보다 빠르나, 화염이 확산되어 발달할수록 화염강도는 선박용 디젤연료가 큰 것으로 분석되었다.

• 대한예방한의학회지
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• 제7권2호
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• pp.121-130
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• 2003

The Musculoskeletal Disease has been ignored or turned away due to the difficulty of diagnosis and the vagueness of judgement up to now. Contrary to other diseases, there were many cases where the character of the Musculoskeletal Disease wasn't revealed through the objective inspection. And that's because the Musculoskeletal Disease appears for the most part due to muscular defect so it is impossible to diagnose the muscle by X-ray diagnosing the bone and it is also impossible to diagnose the fine damage of the muscle or tendon even by advanced device like MRI. As the nervous blood vessels or acupunctures pass through or are next to the muscle, the tension of the muscle put pressure on these so can become the direct or indirect causes of various kinds of pains or intern diseases. But in spite of that, for lack of proper equipment diagnosing the state of the muscle(Shortened.. Relaxed... or Hardened...) the muscle has been disregarded or neglected intentionally or unintentionally. While many people think themselves to be a muscular expert, if they don't see the shape of the muscle, that is just like blind treatment. But as now the equipment diagnosing the state of the muscle is developed, it seems that this problem can be settled. It was attempted in this study that the muscle or skeleton of the Musculoskeletal disease patients was diagno the treatment order and method were decided by a questionnaire survey and simple inspection, and the Musculoskeletal correction exercise using the muscle management and sling system made them escape from the Musculoskeletal disease, turning their muscle into more flexible and stronger muscle. As a result notwithstanding the limited treatment period '12 times', the improvement rate was as high as 74%, which showed that the muscle management and Musculoskeletal correction exercise had a great effect on the symptom improvement of the patients. If the treatment times had increased, the improvement rate also would have increased more.

• Journal of Chest Surgery
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• 제19권4호
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• pp.569-577
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• 1986

Between October 1979 and June 1986, modified Fontan procedures have been performed on 22 patients by the Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine. Twelve patients had tricuspid atresia; one, congenital tricuspid stenosis; five, single ventricle; two, I-transposition of the great vessels; one, double outlet right ventricle, and one, pulmonary atresia with an intact ventricular septum. There were 9 operative deaths [mortality; 40.9%]. The causes of death were right heart failure in six patients and pulmonary venous hypertension in one who misdiagnosed preoperatively. Another two were deceased due to sepsis and cerebrovascular accident at postoperative 35 and 34 days in each. There were 7 patients below 4 years of age at the time of operation and among them 4 patients were deceased. The operative death was not related with patients` age above and below 4[p=0.211]. The relation between operative death of tricuspid anomaly and another cardiac malformations was statistically significant [p=0.048]. The operative procedures with or without valved conduit [woven dacron] was related significantly [p=0.043] in the case of the 21 of the patients, but the modified Fontan operation with a valved conduit was performed early stage in this series. Since 1982, we operated on 4 patients, doing a right atrium-right ventricle anastomosis without a conduit. All survived and remained in functional class I [NYHA]. The right atrial pressure [RAP] was elevated significantly after operation [mean 9.9$\pm$4.8 ~16.9$\pm$3.6 mmHg, p<0.001]. The relation between the postoperative RAP of the survival group [16.5$\pm$4.3 mmHg] and the group who died [17.4$\pm$2.2 mmHg] was statistically significant [p=0.047]. There was no relation between any operative death and any previous palliation. All patients were followed for 4 months to 80 months, except one who was lost to follow up at 2 months following surgery [mean 11.4 months, 238 patient. months]. All were in functional class I with 5 on medications and 7 not. One was reoperated at 70 months following the first operation, due to conduit stenosis. She was moderately impaired in activity, with hepatomegaly after the second operation.

• 동의생리병리학회지
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• 제22권1호
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• pp.13-24
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• 2008

This Chapter mentioned Terror and Palpitation due to Fright(驚悸) and Hemorrhagic disease(血證). Terror and Palpitation due to FrightAcctually Terror(驚) is different from Palpitation(悸). Terror(驚) is one of the seven emotions. But in this case, It refer to the Palpitation and the uneasiness of mind due to one's hearing a strange sound of seeing a strange. Tremulous Pulse can be appear. So Terror(驚) is caused by Exopathic Factors(外因) and belongs to Excess syndrome(實證). Palpitaion(悸) is the sensation of plamus, palpitation and unrest not because of being frightened. It is usurally caused by the deficiency of Ki(氣) and blood(血). So Deep, Thready and weak pulse can be appear. So Palpitaion(悸) is caused by Endopathic Factors and belongs to Deficiency Syndrome. In this Chapter, Terror and Palpitation due to Fright(驚悸) treat with the Kyeji-ke-jakyak-ka-chokchil-moryu-yongkol-kuyuk-tang(桂枝去芍藥加蜀漆牡蠣龍骨救逆湯) and Banha-mahwang-hwan(半夏麻黃丸). There are two type in Hemorrhagic disease(血證). One is bleeding(出血) and another is blood stasis(瘀血). The contents which relate with the Hemorrhagic disease(血證) are Hematemisis(吐血), Rhinorrhagia, Hemafecia(下血). In hemorrhage pathological mechanisms, there are two mechanisms. One is that Fire and Heat(火熱) pressure blood. Another is that cold and deficiency(虛寒) disable Ki(氣) from keeping blood flowing within vessels. Blood stasis(瘀血) can be called Extravasated Blood(惡血), Coagulated Blood, Blood retention(蓄血,積血), Dead Blood(死血) and Emaciation due to Blood disorder(乾血). It refer to a morbid state of unsmooth circulation and blood stagnancy often resulting from Ki(氣) stagnation, Ki(氣) deficiency and accumulation of pathogenic coldness. The symptom of Blood stasis are 'Fullness sensation in the chest, Lip Flaccidity, Cyonotic Tongue and Dryness of Mouth'. And the man who have Blood stasis, want to rinse his mouth with the water, but he can't drink the water because there isn't interior Heat of Excess Type. The symptom of Cyonotic Tongue(舌靑) had influence on diagnosing Blood stasis(瘀血) in offspring.

• 대한한방내과학회지
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• 제26권1호
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• pp.182-198
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• 2005

Object : This study was designed to research whether the protection and inhibitory effects of cardiovascular diseases in L-NAME induced rat or ECV 304 cell lines through the Cell morphological pattern, Tunel assay, LDH activity, heart rate, blood pressure and immunohistochemistric analysis by Boonsimgieum water extract Methods : Nitric oxide(NO) play an important role in normal and pathophysiological cells including as a messenger molecule, neurotransmitter, microbiocidal agent, or dilator of blood vessels and artheriosclerosis, hypertension, myocardial infarction, respectively. Endothelial cell products can modulate the magnitude of a response to a vasoconstrictor, as evinced by the greater constriction after endothelium removal or NO synthesis blockade. To investigate that Boonsimgieum in the potential contribution of the levels of nitric oxide generated by endothelial nitric oxide synthase (eNOS) and the mechanisms of protection against NG-nitro-L-arginine methyl ester (L-NAME), human ECV 304 cells, which normally do not express eNOS, were expressed by L-NAME. L-NAME stimulated rat or cells were found to be resistant to injury and delayed death following the Boonsimgieum. Inhibition of nitric oxide synthesis abolished the protective effect against L-NAME, thrombin and collagen exposure. Interestingly, such effects have been observed during stimulation with agents such as phenylephrine and KCl on L-NAME mediate rats, were damaged by the NOS inhibitor L-NAME. Result : As the result of this study, In group, the anti-apoptosis and necrosis in the cardiovascular system have a potential capacity for prevented, protected and treating the diseases of cardiovascular system, against the necrosis of rat and ECV 304 cells with Caspase 3 and calpain expression by L-NAME is promoted. Conclusion : these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.

• Journal of Pharmaceutical Investigation
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• 제30권1호
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• pp.61-65
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• 2000

Doxazosin, a postsynaptic selective ${\alpha}1-adrenoceptor$ antagonist, is a potent antihypertensive agent which reduces peripheral resistance and blood pressure by vasodilatation of peripheral vessels. It is also used in the treatment of urinary obstruction by benign prostatic hypertrophy. The purpose of the present study was to evaluate the bioequivalence of two doxazosin tablets, $Cardura^{TM}$ (Pfizer Korea Ltd.) and $Cardil^{TM};$ (Kyungdong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Sixteen normal male volunteers, $24.19{\pm}2.48$ years in age and $62.41{\pm}6.66$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 2 mg of doxazosin was orally administered, blood was taken at predetermined time intervals and the concentrations of doxazosin in serum were determined with an HPLC method using spectrofluorometric detector. Pharmacokinetic parameters such as $AUC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in $AUC_t,\;C_{max}\;and\;T_{max}$ between two tablets were -1.54%, -1.51 % and 3.42%, respectively, when calculated against the $Cardura^{TM}$ tablet. The powers $(1-{\beta})$ for $AUC_t,\;C_{max}\;and\;T_{max}$ were all more than 99.00%. Minimum detectable differences $(\Delta)$ at ${\alpha}=0.05\;and\;1-{\beta}=0.8$ were all less than 20% (e.g., 12.73%, 12.84% and 13.01% for $AUC_t,\;C_{max}\;and\;T_{max}$, respectively). The 90% confidence intervals were all within :${\pm}20%$ (e.g., $-8.97{\sim}5.90,\;-9.01{\sim}6.00\;and\;-4.16{\sim}11.05\;for\;AUC_t,\;C_{max}\;and\;T_{max},\;respectively)$. All of the above para- meters met the criteria of KFDA for bioequivalence, indicating that $Cardil^{TM}$ tablet is bioequivalent to $Cardura^{TM}$ tablet.

• 에너지공학
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• 제28권4호
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• pp.1-7
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• 2019

최근 수소충전소 수요 증가에 따라, 산업통상자원부는 LPG, CNG, 주유소 등 기존의 자동차용 연료공급시설 내에 융합, 복합의 형태로 수소충전소 설치가 가능하도록 특례고시를 제정·공포하였다. 수소 융복합충전소는 특례기준 제정 이전까지 국내에서 운영된 사례가 없어, 4계절, 일교차와 같은 환경특성을 감안한 실증이 필요하다. 본 연구에서는, 국내 최초로 실증을 위해 설치된 울산 LPG-수소복합충전소의 충전데이터를 수집하여 분석하였다. 충전데이터는 압축기, 저장용기, 디스펜서에서 발생한 시간별 온도, 압력 데이터이며, 계절별 특성을 비교하기 위해 2018년 7월 중 울산 지역의 최고기온 일과 2018년 1월 중 최저기온 일을 포함하여 4계절 충전데이터를 수집하여 비교하였다. 비교결과, 외기온도의 변화가 수소차 차량용기의 초기온도에 영향을 미치는 것으로 나타났으며, 이는 최종적으로 차량의 충전시간과 충전속도에도 영향을 미치는 것으로 나타났다. 국내 수소충전소 기준(KGS FP217)과 미국의 충전프로토콜(SAE J2601)에서 제시한 한계온도를 초과한 경우는 없어 차량용기에 대한 영향은 없는 것으로 나타났다.