• Title/Summary/Keyword: Presentation ability

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A Case of Meckel's Diverticulum Presented with Acute Abdomen in a Newborn (신생아에서 급성 복증으로 발현된 Meckel 게실 1예)

  • Lim, Jae Young;Jang, Sun Hwa;Cho, Jae Min;Ko, Gyung Hyuck;Park, Eun Sil;Seo, Ji Hyun;Park, Chan Hoo;Woo, Hyang Ok;Youn, Hee Shang
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.8 no.2
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    • pp.222-225
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    • 2005
  • Meckel's diverticulum is generally acknowledged to be the most prevalent congenital anomaly of the gastrointestinal tract. The preoperative diagnosis of Meckel's diverticulum is difficult, especially in neonates, because of the lesions ability to masquerade as one of a variety of much more common abdominal pathologies. Recently we experienced a case of perforated Meckel's diverticulum with mild inflammatory reaction, intestinal adhesion, and small bowel obstruction in a previous healthy 9-day-old neonate. The spontaneous perforation of Meckel's diverticulum in neonate is very rare but serious entity. The course was rapid and progressed to sepsis. So despite its varied presentation, Meckel's diverticulum should be kept in mind as a cause of acute abdomen in neonates.

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Antitumor Activity of Lentivirus-mediated Interleukin -12 Gene Modified Dendritic Cells in Human Lung Cancer in Vitro

  • Ali, Hassan Abdellah Ahmed;Di, Jun;Mei, Wu;Zhang, Yu-Cheng;Li, Yi;Du, Zhen-Wu;Zhang, Gui-Zhen
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.611-616
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    • 2014
  • Objectives: Dendritic cell (DC)-based tumor immunotherapy needs an immunogenic tumor associated antigen (TAA) and an effective approach for its presentation to lymphocytes. In this study we explored whether transduction of DCs with lentiviruses (LVs) expressing the human interleukin-12 gene could stimulate antigen-specific cytotoxic T cells (CTLs) against human lung cancer cells in vitro. Methods: Peripheral blood monocyte-derived DCs were transduced with a lentiviral vector encoding human IL-12 gene (LV-12). The anticipated target of the human IL-12 gene was detected by RT-PCR. The concentration of IL-12 in the culture supernatant of DCs was measured by ELISA.Transduction efficiencies and CD83 phenotypes of DCs were assessed by flow cytometry. DCs were pulsed with tumor antigen of lung cancer cells (DC+Ag) and transduced with LV-12 (DC-LV-12+Ag). Stimulation of T lymphocyte proliferation by DCs and activation of cytotoxic T-lymphocytes (CTL) stimulated by LV-12 transduced DCs pulsed with tumor antigen against A549 lung cancer cells were assessed with methyl thiazolyltetrazolium (MTT). Results: A recombinant lentivirus expressing the IL-12 gene was successfully constructed. DC transduced with LV-12 produced higher levels of IL-12 and expressed higher levels of CD83 than non-transduced. The DC modified by interleukin -12 gene and pulsed with tumor antigen demonstrated good stimulation of lymphocyte proliferation, induction of antigen-specific cytotoxic T lymphocytes and antitumor effects. Conclusions: Dendritic cells transduced with a lentivirus-mediated interleukin-12 gene have an enhanced ability to kill lung cancer cells through promoting T lymphocyte proliferation and cytotoxicity.

Embarrassment; a concept analysis (당혹감(embarrassment); 개념분석)

  • Cho, Eun-Jung;Chung, Bok-Yae
    • Korean Journal of Adult Nursing
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    • v.14 no.2
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    • pp.276-286
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    • 2002
  • Purpose: The concept of embarrassment as an unpleasant emotion is important in caring for those who are in the continuum of illness and health requiring body care and facing sexual problems. In spite of its nursing implication, embarrassment has not been focused in nursing research. Therefore, the purpose of this paper is to develope a conceptual analysis of embarrassment. This analysis would help to understand comprehensively an embarrassing situation in which an intimate relationship between nurse and patient regarding body care of the patient could develope. Futhermore, it would be a basis for developing strategies for prevention of embarrassment which could lead for both patient and nurse to emotionally vulnerable situation because of their failure of self-presentation (impression management). Method: The concept analysis model suggested by Walker and Avant (1988) is used to clarify what is meant by the term 'embarrassment'. Result: This analysis defines the attributes of embarrassment such as follows. First, embarrassment is often attributed to situational factors interrupting a smooth interaction such as intimacy, confusion, vulnerability, exposure of interaction and characteristics of audience. Second, embarrassment is closely related with cognitive factor such as fear of losing face resulted from a behaviour being out of line. Third, embarrassment is closely associated with dispositional factor such as embarrassability. Fourth, embarrassment is an unpleasant and unwanted emotion arising reactively after an interaction had occurred. Fifth, embarrassment encloses physical, physiological and behavioral aspects such as a variety of unique and easily noticeable reactions and a pattern of verbal and non-verbal behaviour for coping in an embarrassing situation. The antecedents were normally socialized adolescents with normal cognitive ability, concern of losing face, embarrassability, embarrassing events related with situational intimacy, confusion, vulnerability, exposure of interaction and characteristics of audience, physical, behavioral blunders resulting in a failure of impression management. The consequences were an emotional coping behaviour, audience's embarrassment responses, and verbal and non-verbal coping strategies of interactional participants. Conclusion: It is hoped that this analysis will stimulate further exploration of this concept and study for developing systematic assessment and nursing practice that diminishes embarrassment of interactional participants.

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A Study on the Extraction and Integration of Learning Object Meta-data using Web Service of Databases (DBMS의 웹서비스를 이용한 학습객체 메타데이터 추출 및 통합에 관한 연구)

  • Choe, Hyun-Jong
    • Journal of The Korean Association of Information Education
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    • v.7 no.2
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    • pp.199-206
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    • 2003
  • XML is becoming a new developing tool of web technology because of its ability of data management and flexibility in data presentation. So it's well researched that the reusability and integration with learning objects such as text, image, sound, video and plug-in programs of web contents in computer education. But the research for storing, extracting and integrating metadata about learning object was needed prior to implementing online learning system to integrate and manage it. Therefore this study propose a new method of using web service of DBMS for extracting learning object's metadata in database server which located in 3-tier system. To evaluate the efficiency of proposed method, The test server and two DBMSs(MS SQL Server 2000 and Oracle 9i) which have 30 metadata was implemented and the response time of it was measured. The response time of it was short, but in order to using this method the additional programming with SAX/DOM was necessary.

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A Study on the Information Environment and SWOT Analysis of e-Plant Portal System (e-Plant 포털 시스템 정보화 환경 및 SWOT 분석)

  • Ahn, Jang-Won;Jee, Sang-Bok;Jeon, Yong-Bae
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2006.11a
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    • pp.539-542
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    • 2006
  • According as acceptance an order results of plant industry increases, ability of plant project management is required and necessity about information technology is augmented. For required information technology, developing information present conditions that consist of partial or unit system of domestic plant companies by synthetic system, development of systematic plant information system that supply standard direction presentation, tools and know-how about information technology need. This study achieved basic research that set information strategy and target by reflect trend of such plant industry, analyze future IT technology trend, international information environment, policy trend etc. and execute SWOT analysis of plant information system through this and present confrontation ways. It is presented confrontation ways by SWOT analysis through this research; (1) Development of education contents that can come forth competent person of plant industry, (2) Practical use of communication means that can offer by real time about informations connected with plant, (3) Offer of knowledge contents that supply various and useful inside and outside of the country's plant knowledge

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High-throughput Gene Expression Analysis to Investigate Host-pathogen Interaction in Avian Coccidiosis

  • Lillehoj Hyun, S.
    • Korean Journal of Poultry Science
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    • v.34 no.1
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    • pp.77-83
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    • 2007
  • Poultry products including meat and eggs constitute a major protein source in the American diet and disease-causing pathogens represent major challenges to the poultry industry. More than 95% of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper-virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

Characteristics of Patients with Occult Hip Fracture after Hip Trauma (고관절 잠행 골절로 진단된 환자의 임상적 특징)

  • Yu, Wookhyun;Kim, Hyejin;Cho, Sukjin;Oh, Sungchan;Kang, Taekyung;Choi, Seungwoon;Ryu, Seokyong
    • Journal of Trauma and Injury
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    • v.26 no.3
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    • pp.125-130
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    • 2013
  • Purpose: This study was undertaken in order to identify the characteristics of patients diagnosed with occult an hip fracture after hip trauma. Methods: We retrospectively reviewed the medical records and radiology reports of all patients who underwent hip skeletal computed tomography (CT) for suspected hip fractures but had normal initial X-rays after hip trauma between August 2006 and January 2012. The variables evaluated included age, gender, body mass index (BMI), accident mechanism, previous fracture, independence, late presentation, ability to bear weight, pain on passive rotation, tenderness of the groin area, diagnosis and treatment. Patients were divided into two groups, with hip fracture (occult hip fracture group) and without hip fracture (no fracture group) to evaluate the characteristics associated with an occult hip fracture. Results: The patients, a total of 139, had a mean age of 58.3 years and included 72 male patients(51.8%). The occult hip fracture group included 43 patients(30.9%). Of those 43, 21 patients(48.8%) had intertrochanteric or trochanteric fractures, 8 patients(18.6%) had femur neck fractures and 14 patients(32.6%) had acetabular fractures. Of the 43, 15 patients(34.9%) needed operative treatment. Age was higher in the occult hip fracture group than it was in the no fracture group($64.4{\pm}19.1$ years vs. $55.5{\pm}23.6$ years, p=0.021). A previous fracture was associated with the presence of a new fracture (p=0.014; OR=3.971, 95% CI=1.314-11.997). Conclusion: Further evaluation of patients who are older or have history of fractures is prudent, even though the initial X-rays are normal.

The Effect of the Elderly Exercise Program Using Elastic-band on the Depression and Physical Self-Efficacy of the Elderly (탄성밴드를 이용한 노인 운동프로그램이 노인의 우울과 신체적 자기효능감에 미치는 영향)

  • Kim, Seongyeol;Park, Wookwun
    • Journal of The Korean Society of Integrative Medicine
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    • v.7 no.4
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    • pp.53-59
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    • 2019
  • Purpose : The purpose of this study was to determine the influence of the elastic-band exercise program for elderly who over 65 years old in terms of depression and physical self efficacy. We aim to suggest interventions with an elastic-band exercise program for elderly. Methods : The study subjects selected were females or males 65 years old or more who could walk without assistance and could talk about daily living without mental or physical disorders. A total of eight subjects understood the purpose of this study and agreed to participate. Before and after the exercise program, the subjects were monitored for changes in their physical self-efficacy and depression. To measure the physical self-efficacy, we used a perceived physical ability scale and physical self-presentation confidence scale (Cronbach α =0.942). To measure depression, we used the geriatric depression scale short form (Korea version, Cronbach α =0.969). The data obtained from each measure were analyzed using the Wilcoxon signed rank test to determine changes from before and after the exercise program. The program consisted of three parts (warm-up, main exercise and cool-down) and included the upper extremities, the lower extremities and trunk exercises with an elastic band (yellow and red). The program lasted for 15 weeks, once a week, with each session lasting for 60 minutes. Results : After 15 weeks of the elastic-band exercise program, there was a significant decrease on the depression scale (p<0.05) and significant improvements on the physical self-efficacy scale (p<0.05). Conclusion : Based upon our results, we demonstrated that the exercise program using the elastic band was effective in improving the depression and physical self-efficacy of the elderly.

Use of Near Infrared Spectroscopy in the Meat Industry

  • Akselsen, Thorvald M.
    • Proceedings of the Korean Society for Food Science of Animal Resources Conference
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    • 2000.11a
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    • pp.1-14
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    • 2000
  • The Near Infrared region of the energy spectrum was first discovered by Hershel in the year 1800. The principles of NIR is based on light absorption of specific organic chemical bonds. The absorption at each wavelength is measured and a spectre is obtained. The spectre is then treated mathematically and with the absorption data is converted to absolute units via a calibration. In the last two decades it has developed dramatically. With the invention of computers and the ability to treat a large amount of data in a very short time the use of NIR for many different purposes has developed very fast. During the last decade with the aid of very powerful PC's the application of NIR technology has become even more widespread. Now or days development of very robust calibrations can be done in a relatively short time with a minimum of resources. The use of Near Infrared Spectroscopy (NIR) in the Meat industry is relatively new. The first installations were taken into operation in the 80ties. The Meat Industry in often referred to as rather conservative and slow to embrace new technologies, they stay with the old and proven methods. The first NIR instruments used by the Meat Industry, and most other industries, were multipurpose build, which means that the sample presentation was not well suited to this particular application, or many other applications for that sake. As the Meat Industry grows and develops to meet the demands of the modern markets, they realise the need for better control of processes and final products. From the early 90 ties and onward the demand for 'rear time' rapid results starts growing, and some suppliers of NIR instruments (and instruments based on other technologies, like X-ray) start to develop and manufacture instrumentation dedicated to the particular needs of the Meat Industry. Today it is estimated that there are approximately 2000 rapid instruments placed in the Meat industry world-wide. By far most of these are used as at-line or laboratory installations, but the trend and need is moving towards real on-line or in-line solutions. NIR is the most cost effective and reproducible analytical procedure available for the twenty first century.

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A Study on the Analysis of Behavioral Changes of Smart Devices and the Presentation of the Improved Model (스마트 디바이스 행동변화 애플리케이션 분석을 통한 개선모델 제시)

  • Park, In-Hwa;Kim, Hae-Na;Lee, Youngho
    • Journal of Digital Convergence
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    • v.12 no.11
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    • pp.225-232
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    • 2014
  • Supply of a smart device has been made with the development of communication networks and growing desire of people to improve the quality of life, the service industry about it have been made with smart devices. Among them, there are various services that can help people change their behavior to healthy life. But it does not have a large impact on the behavior change of performer because its been developed as a general process. Therefore in this study examine development situation about current behavior change applications through application markets. Development current situation can be separated by process to two patterns. As a result we propose behavioral change model that includes integrated change model that one of the behavior theory model, accomplish the goal process of goal setting theory and habit formation phase for automate the changes. Also, we provide appropriate service according to the model that leads motivation, sustainability of the action and positive behavior change to performer. We can expect in many aspects such as ability and motivation than existing service.