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검색결과 192건 처리시간 0.021초

Immunogenomics approaches to study host innate immunity against intestinal parasites

  • Lillehoj, Hyun S.
    • 한국가금학회:학술대회논문집
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    • 한국가금학회 2006년도 제23차 정기총회 및 학술발표회
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    • pp.7-16
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    • 2006
  • Poultry products including meat and eggs constitute a major protein source in the American diet and disease - causing pathogens represent major challenges to the poultry industry. More than 95 % of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper - virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

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거꾸로 수업기반 지구과학 수업모델 개발 및 적용 사례 (The Development and Applied Case of Earth Science Class Model Based on Flipped Learning)

  • 문병찬
    • 대한지구과학교육학회지
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    • 제10권2호
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    • pp.91-103
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    • 2017
  • 이 연구는 거꾸로 수업에 기반 한 지구과학수업 모델을 개발하고, 초등 예비 교사의 과학수업에 수업모델을 적용하여 그 효과를 분석하였다. 본 연구에서 개발한 수업모델은 교실수업에서 이루어지는 모든 내용과 정보를 사전에 학생들에게 제공하는 것으로 거꾸로 수업에서의 선행과제를 대체하였다. 교실수업에서 '지식'내용은 교수에 의한 강의식 설명으로 20분 동안 학생들에게 수행되었으며, 그 후 학생들은 지식과 관련된 심화탐구문제를 토론 협력을 통해 모둠별로 해결하였다. 탐구문제 해결 후, 모둠원 중 발표자로 선정된 한 학생이 모든 학생들 앞에서 모둠에서 수행한 결과를 발표하였다. 14차시 수업 중에 나타난 학생들의 학습과정과 사전에 제공된 학습 자료의 포트폴리오는 기말고사를 대처한 한 학기의 과정평가로 교수에 의해 운영되었다. 수업에 참여한 많은 학생들은 본 수업 모델이 수업에 대한 집중력, 그리고 토론기술과 사고능력을 향상시키는데 있어서 매우 긍정적으로 작용한다는 인식을 나타냈다. 결론 적으로 본 수업모델은 지구과학수업에서 적용하는데 매우 유용하다고 볼 수 있다.

CCTV 카메라 시스템에 의한 ARPA 레이더 추적선박의 자동식별 (Automatic identification of ARPA radar tracking vessels by CCTV camera system)

  • 이대재
    • 수산해양기술연구
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    • 제45권3호
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    • pp.177-187
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    • 2009
  • This paper describes a automatic video surveillance system(AVSS) with long range and 360$^{\circ}$ coverage that is automatically rotated in an elevation over azimuth mode in response to the TTM(tracked target message) signal of vessels tracked by ARPA(automatic radar plotting aids) radar. This AVSS that is a video security and tracking system supported by ARPA radar, CCTV(closed-circuit television) camera system and other sensors to automatically identify and track, detect the potential dangerous situations such as collision accidents at sea and berthing/deberthing accidents in harbor, can be used in monitoring the illegal fishing vessels in inshore and offshore fishing ground, and in more improving the security and safety of domestic fishing vessels in EEZ(exclusive economic zone) area. The movement of the target vessel chosen by the ARPA radar operator in the AVSS can be automatically tracked by a CCTV camera system interfaced to the ECDIS(electronic chart display and information system) with the special functions such as graphic presentation of CCTV image, camera position, camera azimuth and angle of view on the ENC, automatic and manual controls of pan and tilt angles for CCTV system, and the capability that can replay and record continuously all information of a selected target. The test results showed that the AVSS developed experimentally in this study can be used as an extra navigation aid for the operator on the bridge under the confusing traffic situations, to improve the detection efficiency of small targets in sea clutter, to enhance greatly an operator s ability to identify visually vessels tracked by ARPA radar and to provide a recorded history for reference or evidentiary purposes in EEZ area.

Vibration-based structural health monitoring for offshore wind turbines - Experimental validation of stochastic subspace algorithms

  • Kraemer, Peter;Friedmanna, Herbert
    • Wind and Structures
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    • 제21권6호
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    • pp.693-707
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    • 2015
  • The efficiency of wind turbines (WT) is primarily reflected in their ability to generate electricity at any time. Downtimes of WTs due to "conventional" inspections are cost-intensive and undesirable for investors. For this reason, there is a need for structural health monitoring (SHM) systems, to enable service and maintenance on demand and to increase the inspection intervals. In general, monitoring increases the cost effectiveness of WTs. This publication concentrates on the application of two vibration-based SHM algorithms for stability and structural change monitoring of offshore WTs. Only data driven, output-only algorithms based on stochastic subspace identification (SSI) in time domain are considered. The centerpiece of this paper deals with the rough mathematical description of the dynamic behavior of offshore WTs and with the basic presentation of stochastic subspace-based algorithms and their application to these structures. Due to the early stage of the industrial application of SHM on offshore WT on the one side and the required confidentiality to the plant manufacturer and operator on the other side, up to now it is not possible to analyze different isolated structural damages resp. changes in a systematic manner, directly by means of in-situ measurement and to make these "acknowledgements" publicly available. For this reason, the sensitivity of the methods for monitoring purposes are demonstrated through their application on long time measurements from a 1:10 large scale test rig of an offshore WT under different conditions: undamaged, different levels of loosened bolt connections between tower parts, different levels of fouling, scouring and structure inclination. The limitation and further requirements for the approaches and their applicability on real foundations are discussed along the paper.

가상 자전거 시스템을 이용한 노인의 자세균형 증진에 관한 연구 (Study on the Improvement of Postural Balance of the Elderly using Virtual Bicycle System)

  • 권대규;윤영일;박용군;김남균
    • 대한의용생체공학회:의공학회지
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    • 제28권5호
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    • pp.609-617
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    • 2007
  • In this paper, a new rehabilitation training system was developed to improve equilibrium sense of the elderly by combining virtual reality technology with a fixed exercise bicycle. In order to evaluate the effectiveness of the training system, the elderly participated as test subject in the investigation of the influence of different the parameters on postural balance control. We measured three different running modes of virtual bicycle system with two successive sets. The parameters measured were running time, velocity, the weight movement, the degree of the deviation from the road, and the variables about the center of pressure. The repeated training, our results showed that the running capability of the elderly improve compared. In addition, it was found out that the ability of postural control and the equilibrium sense was improved with the presentation of the visual feedback information of the distribution of weight. From the results of this experiment, we showed that our newly developed system might be useful in the diagnosis of equilibrium sense or in the improvement of the sense of sight and, somatic, and vestibular sense of the elderly in the field of rehabilitation training.

주파수 영역에서 영상융합에 의한 영상 워터마킹 기법 (An Image Watermarking Scheme by Image Fusion in the Frequency Domain)

  • 안치현;신필순;황재호;홍충선;이대영;김동현
    • 한국멀티미디어학회논문지
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    • 제8권10호
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    • pp.1411-1420
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    • 2005
  • 본 논문은 영상 데이터의 저작권 보호를 위하여 원영상의 DC 영역 및 각 주파수 영역에 이진 로고 영상의 주파수 계수를 삽입하는 강건한 워터마킹 방법을 제안한다. 패턴을 인식할 수 있는 인간 시각 시스템으로 인해 기호가 숫자보다 훨씬 더 설득력이 있으므로, 워터마크로 64*64 이진 로고 영상의 1 레벨 DWT(discrete wavelet transform) 계수값을 사용한다. 제안한 워터마크 알고리즘은 로고 영상을 1 레벨 DWT하고, 이 DWT 계수값에 인간시각시스템(HVS: human visual system)을 적용하여 영상의 주파수 영역에 있어서 중요 부분(ROI: region of interest)을 기준으로 삽입한다. 따라서 본 워터마킹 기법은 워터마크 검출시 저작권을 바로 확인할 수 있고, 작은 크기의 워터마크를 HVS와 ROI를 이용해 삽입함으로써 비가시성과 견고성이 뛰어나다는 장점이 있다.

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ICT교육이 4차산업 시대에 실버세대들의 적응에 미치는 영향 연구 (The Effects of ICT Education on Aging Adaptation in the 4th Industrial Age)

  • 이해인;정종인;김창석;강신천;김의정
    • 한국정보통신학회:학술대회논문집
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    • 한국정보통신학회 2018년도 춘계학술대회
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    • pp.314-318
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    • 2018
  • 이 연구는 고령화 시대에 실버 인구가 급증하는 4차산업 시대에 따라 새롭게 생기는 지식과 정보활용 능력을 ICT 교육 효과로 인해 실버세대들의 IOT 생활 적응에 미치는 영향에 따른 초점을 두고 분석하여 바림직한 교육 방향을 모색 하는데 목적을 둔다. 문헌연구 및 설문조사로 실제 실버 정보화교육 대상자로 분석한 결과 대체로 정보화 교육은 실버 세대들의 전 삶의 질 향상 및 실제 IOT 기반의 웹 모바일 사용에도 긍정적 효과를 미치고 있음을 확인할 수 있었다. 그러나 정보화 교육의 기간에 따라 역량에 차이를 두고 있었으며, 전 직업 및 학력 등 다양한 기준에 따른 세분화와 이에 따른 4차 산업시대에 맞춤형 교육의 제공 및 실 삶의 질, 후 취업의 ICT 교육의 바람직한 방향에도 개괄적인 논의 및 과정 제시를 병행 한다.

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인지이론에 기초한 객체지향 개발 표기법들의 정보전달 효율 제공 관한 연구 (A Study onImproving the Transferring Efficiency of Information in the Object-oriented Development Notation Methodologies Based on Cognitive Theory)

  • 김원영;김치수
    • 한국정보처리학회논문지
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    • 제6권1호
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    • pp.83-89
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    • 1999
  • OMG에 공인된 객체지향 개발방법에는 Booch, Coad/Yourdon 방법등 많은 공인 방법론들이 객체지향 소프트웨어 개발에 사용되고 있으며, 각각의 방법론마다 상이한 기호를 사용하여 분석 설계과정을 표현하고 있다. 이들 표기방법론 사이에는 개발 정보 전달상의 차이가 존재하고 이러한 차이들은 객체지향 개발 정보의 전달에 장애로 작용하여 정보 전달상에 오류를 발생할 수 있다. 본 연구의 목표는 객체지향 분석, 설계에 사용되는 기존의 도식적 표기법들이 지닌 정보전달 능력을 인지과학에 기초하여 경험적으로 검증하고 각각의 표기법에 사용된 기호들을 시각적으로 강화하여 객체지향 인지부담을 최소화하고 정보전달상의 장애를 파악, 제거하여 설계정보 전달의 효율을 증진시켜 오류발생의 가능성을 감소시키는 방안을 제시하고자 한다.

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혼합학습형태의 『활동과휴식』 통합교과목 개발 및 적용 (Development and Evaluation of an 'Activity and Rest' Integrated Course)

  • 오의금;황선영;이재은;송은경;김민정
    • 성인간호학회지
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    • 제19권4호
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    • pp.624-633
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    • 2007
  • Purpose: This study was conducted to develop an integrated undergraduate course including a PBL based on a blended learning strategy, and evaluate learners' responses. Methods: The learning contents of cardiovascular, respiratory, and musculoskeletal medical systems, and nursing diagnoses of 'activity and rest' domain (NANADA's classification II, 2005) were analyzed. Six clinical scenarios with the clients in different life cycles were developed for PBL. Classical lecture and group presentation with on-line self learning were implemented in addition to PBL. The developed course was implemented on 84 junior nursing students in a university for 7 weeks with 5 hours per day, two days per week. Students were asked to complete structured questionnaires including problem solving, critical thinking, and nursing diagnosis differentiation abilities. Results: Learner's evaluation was positive in problem solving skills and in the differentiation ability of nursing diagnoses relevant to an 'activity and rest' functional health pattern. Conclusion: Development and implementation of integrated courses based on a blended learning method need to be continued to enhance students' thinking and self-directed learning abilities. Supporting strategies for individual learners should be added for successful blended learning such as individual on-line feedback and consideration of individual learning outcomes.

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총괄계획가 시범사업에서 주민참여 기본계획 사례연구 - 홍성 오누이권역을 대상으로 - (A Case Study on Resident Participative Primary Design of Integrated Rural Development Project with Master Planner - Onui Area in Hong Seong -)

  • 정남수
    • 농촌계획
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    • 제21권4호
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    • pp.167-175
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    • 2015
  • The aim of this study is to establish resident-participative primary design of integrated rural development project with master planner by setting principals of open competition and transparent decision-making about village-to-village or business-to-business unit enterprise in Onui area, Hong-seong Gun. For effective processing, software projects such as residents education and rural landscape planning are simultaneously conducted for enhancing project understanding and comprehensive development plan including related post project. Above all, competition teams for individual project were organized to establish the resident-participative primary design using survey tables of residents demand. In 6 months resident-participative processing of primary design, continuous education and visiting to advanced area are conducted in team unit. Strengthened ability of team unit can be used in management and maintenance after project development. To do this, residents with the same opinions gathered as one competition team and identified business plans such as village asset, business location, size, program, and method for land securing. Favorable decision-making process by residents who are audience in project presentation of competition team has conducted. After selecting competition teams, continuos consulting are operated for establishing operation and management for developed or remodeled facilities through repetitive education and visiting advanced area. In this process, unit project suggested by competition team are completed. Preliminary selection was conducted by experts who were entrusted by residents. After residents agreement of project main stream such as major facilities and location, final detailed cost of projects are work out. Suggested process in this study which choose the final project by residents would improve residents' voluntary participation in integrated rural development project through open competition in establishing primary design.