• Environmental Engineering Research
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• 제24권3호
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• pp.484-494
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• 2019

This paper presents a preliminary investigation of the optimum nutrients combination required for bioremediation of spent-engine oil contaminated soil using Box-Behnken-Design. Three levels of cow-manure, poultry-manure and inorganic nitrogen-phosphorus-potassium (NPK) fertilizer were used as independent biostimulants variables; while reduction in total petroleum hydrocarbon (TPH) and total soil porosity (TSP) response as dependent variables were monitored under 6-week incubation. Ex-situ data generated in assessing the degree of biodegradation in the soil were used to develop second-order quadratic regression models for both TPH and TSP. The two models were found to be highly significant and good predictors of the response fate of TPH-removal and TSP-improvement, as indicated by their coefficients of determination: $R^2=0.9982$ and $R^2=1.000$ at $p{\leq}0.05$, respectively. Validation of the models showed that there was no significant difference between the predicted and observed values of TPH-removal and TSP-improvement. Using numerical technique, the optimum values of the biostimulants required to achieve a predicted maximum TPH-removal and TSP-improvement of 67.20 and 53.42%-dry-weight per kg of the contaminated soil were as follows: cow-manure - 125.0 g, poultry-manure - 100.0 g and NPK-fertilizer - 10.5 g. The observed values at this optimum point were 66.92 and 52.65%-dry-weight as TPH-removal and TSP-improvement, respectively.

• Journal of Ginseng Research
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• 제46권6호
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• pp.711-721
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• 2022

The immune system is one of the most important parts of the human body and immunomodulation is the major function of the immune system. In response to outside pathogens or high inflammation, the immune system is stimulated or suppressed. Thus, identifying effective and potent immunostimulants or immunosuppressants is critical. Ginsenosides are a type of steroid saponin derived from ginseng. Most are harmless to the body and even have tonic effects. In this review, we mainly focus on the immunostimulatory and immunosuppressive roles of two types ginsenosides: the protopanaxadiol (PPD)-type and protopanaxatriol (PPT)-type. PPT-type ginsenosides include Rg1, Rg2, Rh4, Re and notoginsenoside R1, and PPD-type ginsenosides include Rg3, Rh2, Rb1, Rb2, Rc, Rd, compound K (CK) and PPD, which activate the immune responses. In addition, Rg1 and Rg6 belong to PPT-type ginsenosides and together with Rg3, Rb1, Rd, CK show immunosuppressive properties. Current explorations of ginsenosides in immunological areas are in the preliminary stages. Therefore, this review may provide some novel ideas to researchers who study the immunoregulatory roles of ginsenosides.

• Nuclear Engineering and Technology
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• 제53권6호
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• pp.2038-2045
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• 2021

The main objective of this work is to propose a reliable routine standard operation procedures (SOP) for structural health monitoring and diagnosis of nuclear power plants (NPPs). At present, NPPs have monitoring systems that can be used to obtain the quantitative health record of containment (CTMT) buildings through system identification technology. However, because the measurement signals are often interfered with by noise, the identification results may introduce erroneous conclusions if the measured data is directly adopted. Therefore, this paper recommends the SOP for signal screening and the required identification procedures to identify the dynamic characteristics of the CTMT of NPPs. In the SOP, three recommend methods are proposed including the Recursive Least Squares (RLS), the Observer Kalman Filter Identification/Eigensystem Realization Algorithm (OKID/ERA), and the Frequency Response Function (FRF). The identification results can be verified by comparing the results of different methods. Finally, a preliminary CTMT healthy record can be established based on the limited number of earthquake records. It can be served as the quantitative reference to expedite the restart procedure. If the fundamental frequency of the CTMT drops significantly after the Operating Basis Earthquake and Safe Shutdown Earthquake (OBE/SSE), it means that the restart actions suggested by the regulatory guide should be taken in place immediately.

• Geomechanics and Engineering
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• 제36권3호
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• pp.247-258
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• 2024

Tailings are waste materials of mining operations, consisting of a mixture of clay, silt, sand with a high content of unrecoverable metals, process water, and chemical reagents. They are usually discharged as slurry into the storage area retained by dams or earth embankments. Poor knowledge of the hydro-mechanical behaviour of tailings has often resulted in a high rate of failures in which static liquefaction has been widely recognized as one of the major causes of dam collapse. Many studies have dealt with the static liquefaction of coarse soils in saturated conditions. This research provides an extension to the case of silty tailings in unsaturated conditions. The static liquefaction resistance was evaluated in terms of stress-strain behavior by means of monotonic triaxial tests. Its dependency on the preparation method, the volumetric water content, the void ratio, and the degree of saturation was studied and compared with literature data. The static liquefaction response was proved to be dependent mainly on the preparation technique and degree of saturation that, in turn, controls the excess of pore pressure whose leading role is investigated by means of the relationship between the -B Skempton parameter and the degree of saturation. A preliminary interpretation of the static liquefaction response of Stava tailings is also provided within the Critical State framework.

• 한국치위생학회지
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• 제8권3호
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• pp.161-175
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• 2008

With the change of medical environment, people are taking interest not just in treatment but in the prevention of oral diseases. As people's interest in oral diseases increases, the number of dental institutions is increasing continuously and this is heightening the necessity and importance of professional dental hygienists equipped with expert knowledge of oral health. Thus the present study purposed to survey and analyze the current state and weight of works carried out by dental hygienists, and to propose dental hygienists' works desirable in the medical environment changing its focus from treatment to prevention. The results of this study are as follows; 1. In the results of dividing dental hygienists' works into oral examination and preliminary examination, preventive works, assistance to dental treatment, oral health education, hospital administration and management, and surveying the performance rate of these works, the work of the highest performance rate in preliminary examination was collection of patients' systemic history (87.6%). It was also scaling (96.9%) in preventive dental treatment, preparation for treatment (96.5%) in assistance to dental treatment, education on the toothbrushing method (92.3%) in oral health education, and tool disinfection and management (72.2%) in hospital administration and management. 2. When the performance rate was surveyed according to age, institution, and work experience, the performance rate by work area was highest in dental hygienists aged between 27~28, those working at a dental clinic, and those with 4~6 years' work experience. 3. The weight of dental hygienists' works was high in order of assistance to dental treatment (59.1%), observation of oral health condition and preliminary examination (12.4%), oral health education (12.4%), hospital administration and management (10.4%), and preventive dental treatment (5.8%), but in the results of surveying perception on the importance of works, the importance was high in order of oral health education (34.7%), preventive dental treatment (29.0%), observation of oral health condition and preliminary examination (19.3%), assistance to dental treatment (11.2%), and hospital administration and management (5.8%), showing that the weight of works carried out current was different from perception on the weight of works regarded as important. 4. To the question on parts to be developed in response to the change of medical environment, the most frequent answers were the establishment of their roles as preventive dental practitioners (75.7%), and the establishment of their roles as oral health educators (74.9%). This was consistent with the works that dental hygienists gave the highest weight to, and suggested that dental hygienists regarded preventive dental treatment as most important. Development of abilities to give counsel to patients was 55.2%, acquisition of theoretical knowledge of dental treatment 42.1%, improvement in quality as a hospital manager 28.2%, and acquisition of skills to assist dental treatment 23.2%. These show that, even with regard to the development of future oriented dental hygienists' capacities, assistance to dental treatment was perceived less important as it was with regard to the importance of work.

• 응용통계연구
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• 제29권4호
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• pp.595-611
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• 2016

일반적으로 독성학 또는 약리학에서는 자료를 분석할 때 Hill Model과 같은 비선형 회귀모형을 사용한다. 비선형 회귀모형에서 모수의 추정량과 그것의 불확실성(uncertainty)에 대한 측도의 추정은 오차의 분산 구조에 영향을 받게 된다. 따라서 자료가 등분산인지 혹은 이분산인지에 따라 사용하여야 할 추정 방법이 달라져야 한다. 그러나 일반적으로 자료를 실제로 분석하기 전에는 오차의 분산구조에 대해서 잘 알 수 없다. 그러므로 오차의 분산구조에 로버스트한 추정 방법을 개발하는 것은 중요한 문제이다. 본 논문에서는 예비검정 방법을 기반으로 한 비선형 회귀모형에서의 모수 추정 방법을 제안하였다. 오차 분산의 등분산성에 대한 간단한 예비검정의 결과에 따라 보통 최소제곱 추정(ordinary Least Square Estimation) 방법과 반복 가중 최소제곱 추정(iterative weighted least square estimation) 방법을 사용하는 추정량을 정의하였다. 제안된 추정량은 모의실험 연구를 통하여 기존의 표준적인 추정량들과 그 성능을 비교하였다. 또한 미국의 National Toxicology Program으로부터 얻어진 실제자료를 사용하여 추정 방법들을 비교하였다.

• 대한기계학회논문집A
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• 제33권12호
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• pp.1401-1409
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• 2009

All the forces in the real world act dynamically on structures. Design and analysis should be performed based on the dynamic loads for the safety of structures. Dynamic (transient or vibrational) responses have many peaks in the time domain. Topology optimization, which gives an excellent conceptual design, mainly has been performed with static loads. In topology optimization, the number of design variables is quite large and considering the peaks is fairly costly. Topology optimization in the frequency domain has been performed to consider the dynamic effects; however, it is not sufficient to fully include the dynamic characteristics. In this research, linear dynamic response topology optimization is performed in the time domain. First, the necessity of topology optimization to directly consider the dynamic loads is verified by identifying the relationship between the natural frequency of a structure and the excitation frequency. When the natural frequency of a structure is low, the dynamic characteristics (inertia effect) should be considered. The equivalent static loads (ESLs) method is proposed for linear dynamic response topology optimization. ESLs are made to generate the same response field as that from dynamic loads at each time step of dynamic response analysis. The method was originally developed for size and shape optimizations. The original method is expanded to topology optimization under dynamic loads. At each time step of dynamic analysis, ESLs are calculated and ESLs are used as the external loads in static response topology optimization. The results of topology optimization are used to update the design variables (density of finite elements) and the updated design variables are used in dynamic analysis in a cyclic manner until the convergence criteria are satisfied. The updating rules and convergence criteria in the ESLs method are newly proposed for linear dynamic response topology optimization. The proposed updating rules are the artificial material method and the element elimination method. The artificial material method updates the material property for dynamic analysis at the next cycle using the results of topology optimization. The element elimination method is proposed to remove the element which has low density when static topology optimization is finished. These proposed methods are applied to some examples. The results are discussed in comparison with conventional linear static response topology optimization.

• 한국지반공학회논문집
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• 제37권12호
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• pp.57-71
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• 2021

잔교식 구조물은 상판을 말뚝 또는 기둥으로 지지하는 형식의 항만 구조물로서, 경사 말뚝을 설치하여 지진하중과 같은 수평하중을 부분적으로 축력으로 분담하도록 설계할 수 있다. 기준서에서는 잔교식 구조물 내진설계 시 예비 설계 방법으로 응답스펙트럼해석법을 활용하도록 설명하고 있으며, 응답스펙트럼 해석 시 말뚝을 가상고정점 방법 및 지반스프링 방법을 적용하여 모델링하도록 제시하고 있다. 최근 응답스펙트럼해석 시 구조물의 동적 응답을 적절히 모사하는 모델링 방법을 도출하기 위해 연직 말뚝으로 구성된 잔교식 구조물에 관한 몇몇 연구들이 수행되어 왔으나, 현재까지 경사말뚝이 적용된 잔교식 구조물에 대한 응답스펙트럼해석 관련 연구는 부족한 실정이다. 그러므로 본 연구에서는 경사말뚝이 설치된 잔교식 구조물의 모델링 방법에 따른 내진성능을 평가하기 위해 동적원심모형실험과 더불어 응답스펙트럼 해석을 수행하였다. 실험 및 해석을 비교한 결과, 경사말뚝이 설치된 잔교식 구조물의 경우 실제 응답을 적절히 모사하기 위해 Terzaghi(1955)가 제시한 수평지반반력상수를 활용하여 모델링을 수행하는 것이 적절한 것으로 나타났다.

• 한국지진공학회논문집
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• 제18권3호
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• pp.141-150
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• 2014

A methodology to evaluate the seismic performance of interface piping systems that cross the isolation interface in the seismically isolated nuclear power plant (NPP) was developed. The developed methodology was applied to the safety-related interface piping system to demonstrate the seismic performance of the target piping system. Not only the seismic performance for the design level earthquakes but also the performance for the beyond design level earthquakes were evaluated. Two artificial seismic ground input motions which were matched to the design response spectra and two historical earthquake ground motions were used for the seismic analysis of piping system. The preliminary performance evaluation results show that the excessive relative displacements can occur in the seismically isolated piping system. If the input ground motion contained relatively high energy in the low frequency region, we could find that the stress response of the piping system exceed the allowable stress level even though the intensity of the input ground motion is equal to the design level earthquake. The structural responses and seismic performances of piping system were varied sensitively with respect to the intensities and frequency contents of input ground motions. Therefore, for the application of isolation system to NPPs and the verification of the safety of piping system, the seismic performance of the piping system subjected to the earthquake at the target NPP site should be evaluated firstly.

• 전자공학회논문지T
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• 제36T권1호
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• pp.19-24
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• 1999

In\sub 2\O\sub 3\ 계 산화물 반도체형 후막센서의 ppb 범위의 오존에 대한 감지특성을 살펴보았다. In\sub 2\O\sub 감지막은 오존에 감도가 상당히 높았지만 안정된 신호를 얻을 수 없었다. In\sub 2\O\sub에 3wt.% 의 Fe\sub 2\O\sub 3\를 첨가한 경우에는, 순수한 In\sub 2\O\sub 와 비교할 때 응답 시간과 감도에 있어서 감지 특성의 향상이 관찰되었지만, 센서 신호가 시간에 따라 계속 증가되는 경향은 크게 개선되지 않았다. 그러나 In\sub 2\O\sub:Fe\sub 2\O\sub 3\ 혼합 분말의 열처리는 감도가 감소하기는 하였지만 센서의 오존 응답 및 회복 특성을 증진시켰다. 특히 1300℃ 정도의 고온에서 혼합 분말을 열처리 하여 제조한 감지막은 감도의 감소는 있었지만 550℃ 의 측정 온도에서 빠른 응답 및 회복 특성과 센서 신호가 최대값으로 빠르게 수렴함을 확인할 수 있었다. 또한 이들 센서는 오존에 대해 센서 신호의 선형적인 농도 의존성을 나타내었으며, 반복 실험을 행할 때 센서 신호의 재현성을 보여주었다. 따라서 본 연구에서 제조한 후 막 가스센서를 사용하여 ppb 범위의 오존 농도를 신뢰성있게 측정할 수 있음을 확인할 수 있었다.