• 정신신체의학
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• 제12권2호
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• pp.122-134
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• 2004

연구목적 : 본 연구의 목적은 분노반응 척도를 개발하고 임상에 적용하고자 하는 데 있다. 방법: 성인 정상인 123명을 대상으로 분노반응 척도 예비설문을 시행하여 16개 문항을 추출하였다. 그 다음에 이 문항들이 포함된 설문을 정상인 258명을 대상으로 실시하였다. 상기 척도의 임상적 적용은 환자군 189명(불안장애 59명, 우울장애 72명, 신체형장애 58명)을 대상으로 하였다. 결과: 이 자료들을 요인분석한 결과 4개의 하위요인 즉 공격성반응, 짜증반응, 도피반응, 분노억압반응이 추출되었다. 상기 척도의 신뢰도는 정상인 53명에게 2주 간격으로 검사-재검사를 시행, 분석한 결과 4개 하위척도 점수와 척도 전체 점수간의 상관계수가 .53-.71로 모두 유의한 상관성을 보였다. 한편 내적 일치도는 4개 하위척도의 Cronbach's ${\alpha}$가 .62-.72, 척도 전체의 Cronbach's ${\alpha}$가 .76로 유의한 수준을 보였다. 공존 타당도의 평가는 공격성질문지 (Aggression Questionnaire) 총점, 상태-특성분노표출척도(State-Trait Anger Expression Inventory), 스트레스반응척도(Stress Response Inventory)의 분노 및 공격성 하위척도, Symptom Checklist-90-Revised (SCL-90-R)의 적대감 하위척도를 사용하였다. 환자군과 정상군 간에 척도의 전체 점수와 하위척도 점수를 비교한 결과 도피반응과 분노억압반응 하위척도에서만 각각 유의한 차이를 보였고 공격성 및 짜증반응, 척도 전체 점수에서는 유의한 차이를 보이지 않았다. 도피반응 하위척도 점수에서 우울장애군과 신체형장애군은 각각 정상군보다 유의하게 더 높았다. 결론: 이상의 결과들은 분노반응 척도가 신뢰도 및 타당도가 모두 유의한 수준의 도구이고, 특히 도피반응은 우울장애군 및 신체형장애군의 특징적인 분노반응일 가능성을 시사해 준다.

• 한국수소및신에너지학회논문집
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• 제28권1호
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• pp.98-105
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• 2017

In recent years, compression ignition engine has been equipped with some control devices such as common rail injection system and turbocharger. In order to control the large number of input parameter appropriately in consideration of $NO_x$, HC and engine power as the engine output objectives. The model construction which reproduces the characteristic value of $NO_x$, HC and engine power from input parameter is needed. In this research, the stepwise method was applied to construct the compression ignition engine model. By using the preliminary experimental data of single cylinder compression ignition engine, the prediction model of $NO_x$, HC and engine power on single injection compression ignition engine was built and compared with the main experimental data.

• Advances in environmental research
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• 제1권4호
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• pp.289-304
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• 2012

Tris (2-methyl-1-aziridinyl) phosphine oxide (MAPO) is extremely poisonous and persistent in aqueous media. An efficient UV/nano$TiO_2$ process was employed for its mineralization in a high duty falling film photo-reactor based on an experimental design scheme that considers interactions between the main variables. The influencing variables and their range were determined with preliminary studies. The results show substrate mineralization to some extent under mild conditions of: T = $30^{\circ}C$, pH = 8.5, $[MAPO]_0=60\;mg\;L^{-1}$ and $[TiO_2]=110\;mg\;L^{-1}$. The relative importance of the influencing parameters were initial pH > temperature > $[MAPO]_0$ > [$TiO_2$]; while the interdependence of all the parameters was significant. Accordingly, a reduced quadratic expression was developed. Meanwhile, mineralization kinetic studies, based on chemical oxygen demand, revealed a power law model with order of 2.6 during process time until 150 min.

• Structural Engineering and Mechanics
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• 제63권1호
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• pp.47-53
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• 2017

The fundamental goal of this study is to minimize the uncertainty of the median fragility curve and to assess the structural vulnerability under earthquake excitation. Bayesian Inference with Markov Chain Monte Carlo (MCMC) simulation has been presented for efficient collapse response assessment of the independent intake water tower. The intake tower is significantly used as a diversion type of the hydropower station for maintaining power plant, reservoir and spillway tunnel. Therefore, the seismic fragility assessment of the intake tower is a pivotal component for estimating total system risk of the reservoir. In this investigation, an asymmetrical independent slender reinforced concrete structure is considered. The Bayesian Inference method provides the flexibility to integrate the prior information of collapse response data with the numerical analysis results. The preliminary information of risk data can be obtained from various sources like experiments, existing studies, and simplified linear dynamic analysis or nonlinear static analysis. The conventional lognormal model is used for plotting the fragility curve using the data from time history simulation and nonlinear static pushover analysis respectively. The Bayesian Inference approach is applied for integrating the data from both analyses with the help of MCMC simulation. The method achieves meaningful improvement of uncertainty associated with the fragility curve, and provides significant statistical and computational efficiency.

• 한국환경과학회지
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• 제26권2호
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• pp.257-263
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• 2017

The aim of this study was to evaluate the efficacy of red ginseng drinks as school meal drinks for 456 middle and high school students in Cheongdo-gun, North Gyeongsang Province. In preliminary studies, we focused on saponin with an efficacy of Rg 1 and Rg 2 in prepared red ginseng drinks. The health benefits and sensory characteristics were also investigated. For the frequency analysis, the satisfaction of the drinks as beverages serving as a school meal was relatively low, and the demand for fruit drinks was high. The result of sensory evaluations indicated a positive response of > 50.0% for the container packaging and design, daily intake, and tastes. Regarding the correlation analysis on red ginseng drinks, there were significant differences (p < 0.01) in the response to packaging (a daily intake) and design. In addition, health and learning benefits showed a very high correlation at the p < 0.01 significance level.

• Natural Product Sciences
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• 제19권4호
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• pp.324-328
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• 2013

Soy (Glycine max, family Leguminosae) contains isoflavones and saponins as main constituents. In our preliminary study, soybean ethanol extract (SE) ameliorated scopolamine-induced memory impairment in mice in the passive avoidance task. Therefore, to confirm its ameliorating effect for memory impairments, we measured its effect in scopolamine-induced memory-impaired mice in Morris water maze task. SE significantly prevented scopolamine-induced memory impairment in the Morris water maze task. SE also increased the swimming time within quadrant section of the platform on the day after the final training session test. SE protected the reduction of brain-derived neurotrophic factor (BDNF) expression and cAMP response element-binding protein (CREB) phosphorylation in the hippocampi of scopolamine-treated mice. However, SE did not inhibit acetylcholinesterase. To understand the possible role of soysaponins in memory impairments, we prepared soyasaponins-rich (butanol) fraction of soybean (SRF) and investigated its protective effect against in the passive avoidance and Morris water maze tasks. SRF ameliorated scopolamine-induced memory impairment in mice. The memory impairment-ameliorating effect of SRF was more effective than that of SE. Based on these findings, soybean may improve memory impairment by regulating CREB phosphorylation and BDNF expression.

• International Journal of Naval Architecture and Ocean Engineering
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• 제2권4호
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• pp.217-222
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• 2010

Since 1980's, optimum design techniques for ship structural design have been developed to the preliminary design which aims at minimum weight or minimum cost design of mid-ship section based on analytic structural analysis. But the optimum structural design researches about the application for the detail design of local structure based on FEA have been still insufficient. This paper presents optimization technique for the detail design of a racing motor boat. To improve the performance and reduce the damage of a real existing racing boat, direct structural analyses; static and non-linear transient dynamic analyses, were carried out to check the constraints of minimum weight design. As a result, it is shown that the optimum structural design of a racing boat has to be focused on reducing impulse response from pitching motion than static response because the dynamic effect is more dominant. Optimum design algorithm based on nonlinear finite element analysis for a racing motor boat was developed and coded to ANSYS, and its applicability for actual structural design was verifed.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2005년도 학술발표회 논문집
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• pp.90-101
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• 2005

For the site characterization at two representative inland areas, Gyeongju and Hongsung, in Korea, in-situ seismic tests containing boring investigations and resonant column tests were performed and site-specific ground response analyses were conducted using equivalent linear as well as nonlinear scheme. The soil deposits in Korea were shallower and stiffer than those in the western US, from which the site classification system and site coefficients in Korea were derived. Most sites were categorized as site classes C and D based on the mean shear wave velocity to 30 m, Vs30 ranging between 250 and 650 m/s. Based on the acceleration response spectra determined from the site-specific analyses, the site coefficients specified in the Korean seismic design guide underestimate the ground motion in the short-period band and overestimate the ground motion in mid-period band. These differences can be explained by the differences in the bedrock depth and the soil stiffness profile between Korea and western US. The site coefficients were re-evaluated and the preliminary site classification system was introduced accounting for the local geologic conditions on the Korean peninsula.

• Radiation Oncology Journal
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• 제6권1호
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• pp.75-80
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• 1988

Twenty seven lesions of 25 patients with locally advanced malignant tumors were treated with combined hyperthermia introduced by microwave and ultrasound and radiotherapy. Most of all patients were failed with previous conventional therapeutic trial. Hyperthermia had been done immediately after radiotherapy, twice a week, $43^{\circ}C$ for one hour and radiotherapy had been done 5 fractions per week with fraction size of 2Gy upto 30 to 60Gy. Conclusions are as follows. 1. Total response rate (PR+PR) to thermoradiotherapy with microwave and ultrasound was $81\%$. 2. Tumor depth, minimum temperature of tumor center, number of heat fraction and radiation dose were statistically significant factors affecting response. 3. Hyperthermia with microwave and ultrasound can be used efficiently to control locally advanced malignant disease whether previously received near tolerance dose of radiotherapy or not.

• 아동학회지
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• 제26권6호
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• pp.73-88
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• 2005

This study aimed to develop a reliable and valid developmental test for toddlers and preschoolers. A trial form of the test with 230 items in 5 domains(cognitive, physical, language, social, and self-help) was constructed and administered to 200 children from 2 to 5-year-olds. Item analysis indicated that most items selected in cognitive, physical, and indicated domain were acceptable in terms of item response rate and item discrimination. However, some items in social and self-help domain did not show clear age trends in item response, but mostly were adequate in item discrimination. Based on item analysis, 112 items were selected for the final form : 24 items each for the cognitive, physical, and language domain; 20 items each for the social and self-help domain. Reliability indicated by internal consistency coefficients(KR-20) were high in all domains. Validity of the test was supported by inter-correlations among 5 domains(.61 to .93), and significant age differences in domain scores.