• The Journal of Korean Medicine
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• v.30 no.1
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• pp.83-94
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• 2009

Background and Objectives: The skin barrier protects skin against a harmful environment. Its function includes an antimicrobial barrier as well as a physical barrier. Stress is harmful to the skin barrier and there are many studies on this, but there are few about the effect of stress during pregnancy on the skin barrier of offspring. The aim of this study was to investigate the effect of stress during pregnancy on the skin barrier of offspring by examination with the naked eye, cortisol, weight, TEWL and histologic tests. Materials and Methods: Male hairless mice ten weeks old were coupled with females for three days. After twelve days the females were divided into two groups. We stressed one group and not the other group. The offspring from the non-stressed (N group) and stressed (S group) grew up until four weeks. The S group was exposed to chronic mild stress using the chronic stress model protocol modified method of Wilner and Towell for a week. We made examinations with the naked eye, assessment of cortisol, weight, TEWL, and histologic test to contrast the S group with the N group. Statistical analysis was performed by using Mann-Whitney and Friedman test. Statistical significance was achieved if the probability was less than 5% (p<0.05). Results: 1. By making an examination with the naked eye, S group showed papules, creases and dryness on their skin, but N showed no change compared with normal skin. 2. There was no statistically significant difference between S group and N group in cortisol (p>0.05). 3. There was no statistically significant difference between S group and N group in weight. N group had less weight than S group (p<0.05). 4. There was no statistically significant difference between S group and N group in TEWL (p>0.05). 5. There was no statistically significant difference between S group and N group in TEWL recovery (p>0.05). 6. In TEWL and TEWL recovery, there was statistically significant difference by time between S group and N group (p<0.005). Histologically, S group showed a thicker epidermis and epidermal crest than N group. Conclusions: We found that stress during pregnancy has negative effects on the skin barrier of offspring. Though there were no statistically significant differences between S group and N group in TEWL recovery, we found evidence that the recovery of skin barrier function is interrupted by stress during pregnancy by examination with both the naked eye and histology.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.125-134
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• 2006

During the prenatal period, the development of the individual is influenced by a host of environmental factors. Exposure to noise stress during pregnancy was determined to result in the retardation of growth, a reduction in neurogenesis, and an impairment of spatial learning ability in the rat pups. In the present study, we have attempted to characterize the effects of prenatal treatment with Cnidium officinale Makino on spatial memory and neurogenesis in the hippocampus of rat pups born from maternal rats exposed to noise stress during pregnancy. Prenatal treatment with Cnidium officinale Makino was shown to increase neurogenesis and enhanced spatial learning ability in rat pups born from maternal rats exposed to noise stress. In this study, we have determined that prenatal treatment with Cnidium officinale Makino can stimulate spatial development and neurogenesis in the brain of the fetuses exposed to prenatal stresses.

• Journal of Korean Academy of Nursing
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• v.46 no.5
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• pp.653-662
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• 2016

Purpose: The purpose of this study was to identify the influences of oral health behaviors, depression, and stress on periodontal disease in pregnant women. Methods: The participants in this study were 129 pregnant women. Data were collected using questionnaires which included individual characteristics, oral health care behaviors, the Center for Epidemiological Studies-Depression scale (CES-D), a global measure of perceived stress, and pregnancy stress. A dentist measured periodontal probing depth and classified stages of periodontal disease according to the Community Periodontal Index (CPI). Data were analyzed using descriptive statistics, Pearson correlation, and multiple regression. Results: Periodontal disease had significant correlations with oral health care behaviors (r=-.56, p <.001), perceived stress (r=.44 p <.001), pregnancy stress (r=.37 p <.001), diet (r=-.33, p <.001) and depression (r=.18 p =.046). Factors influencing periodontal disease for these pregnant women were being in the 2nd (${\beta}=.27$, p <.001) or 3rd trimester (${\beta}=.45$, p <.001), having a pregnancy induced disease (${\beta}=.20$, p =.002), performing higher oral health behaviors (${\beta}=-.30$, p <.001), and having higher perceived stress (${\beta}=.17$, p =.028). The explanation power of this regression model was 61.6% (F=15.52, p <.001). Conclusion: The findings of this study indicated that periodic assessment of periodontal disease is essential for pregnant women who are in 2nd or 3rd trimester and have pregnancy induced diseases. Enhancing oral health care behaviors and reducing perceived stress are indicated as effective strategies to reduce periodontal disease in pregnant women.

• Journal of Convergence for Information Technology
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• v.11 no.5
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• pp.50-56
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• 2021

This study was done develop the factors that affect the quality of life among pregnant women supportive, stress and anxiety. This study was a descriptive survey of 117 pregnant women residing in two regions D and S. Before the questionnaire, the purpose and purpose of the study were explained and proceeded SPSS 21.0 was used for the data, frequency analysis, variance analysis, t-test, correlation analysis, and rare analysis. The data was collected from January to February 2020. The results of this study are as follows. The differences in quality of life of pregnant women according to general characteristics showed significant differences in sleep time, economic status, health status, activity status and pregnancy cycle. Variables affecting quality of life were social support (β= .432, p= .000), pregnancy stress (β=- .407, p= .000), anxiety (β=- .182, p= .010). If pregnant women experience pregnancy stress and anxiety, the quality of life may be degraded, so it is necessary to develop a health promotion program for pregnant women.

• Journal of Korean Academy of Nursing
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• v.47 no.3
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• pp.357-366
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• 2017

Purpose: The aim of this study was to determine the influence of various factors on preterm labor symptoms (PLS) and preterm birth (PB). Methods: This prospective cohort study included 193 women in the second stage of pregnancy. Multiple characteristics including body mass index (BMI), smoking, and pregnancy complications were collected through a self-report questionnaire. Pregnancy stress and PLS were each measured with a related scale. Cervical length and birth outcome were evaluated from medical charts. Multiple regression was used to predict PLS and logistic regression was used to predict PB. Results: Multiple regression showed smoking experience, pregnancy complications and pregnancy specific stress were predictors of PLS and accounted for 19.2% of the total variation. Logistic regression showed predictors of PB to be twins (OR=13.68, CI=3.72~50.33, p<.001), shorter cervix (<25mm) (OR=5.63, CI=1.29~24.54, p<.05), BMI >25 ($kg/m^2$) (OR=3.50, CI=1.35~9.04, p<.01) and a previous PB (OR=4.15, CI=1.07~16.03, p<.05). Conclusion: The results of this study show that the multiple factors affect stage II pregnant women can result in PLS or PB. And preterm labor may predict PB. These findings highlight differences in predicting variables for pretrm labor and for PB. Future research is needed to develop a screening tool to predict the risk of preterm birth in pregnant women.

• Journal of Animal Reproduction and Biotechnology
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• v.36 no.4
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• pp.194-202
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• 2021

In this study the effect of vitamin C administration on pregnancy rates during summer heat stress in dairy cows was examined. A total of 80 Holstein-Friesian cows were divided into control and treatment groups (n = 40 each). Control group animals were given 10 mL isotonic normal saline, and treatment group, Vitamin C (4 mg/kg) on artificial insemination day (day 0) and 4^th, 8^th and 12^th day post insemination. Pregnancy diagnosis was performed on 30^th day post insemination by ultrasonography. Blood samples were randomly taken from 11 animals from each group. Serum P₄, GSH, MDA and plasma 8-OHdG levels were determined by using ELISA method. Results showed that 8-OHdG levels were lower in treatment group on day 4, 8 and 12 (p < 0.05) compared with the control group. Similarly, pregnancy rate was higher in treatment group (32.5%) than control (22.5%), respectively. However, MDA, P₄ and GSH levels were similar in both groups at 4^th, 8^th and 12^th day. A gradual increase in P₄, and MDA levels, and a strong positive correlation between 0, 4^th (r = 0.54), 4, 8^th (r = 0.59) and 8, 12^th (r = 0.51) day was found. Similarly, GSH levels also showed positive correlation at days 0, 4^th (r = 0.47) and 4, 8^th (r = 0.56). However, a strong negative correlation (r = -0.56) between MDA day 0, and GSH day 8 was found. In conclusion, vitamin C application during insemination period in postpartum cows increases pregnancy rate, and reduces oxidative stress metabolite 8-OHdG levels.

• The Journal of the Convergence on Culture Technology
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• v.4 no.1
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• pp.85-93
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• 2018

The purpose of this study was to investigate the effects of health promoting behaviors on marriage and pregnancy in 227 female college students at three universities in C city. The descriptive sruvey was conducted from 15 November to 1 December 2017 in a structured questionnaire on health promotion behaviors and marriage and pregnancy. As a of the analysis, sub - factors (personal hygiene, nutrition habit, substance abuse, exercise, stress management, self-actualization) of health promoting behaviors showed significant correlation with marital and pregnancy perception (p<.001), hierarchical regression analysis showed that stress management was the most influential factor for marriage and pregnancy (Non-standardization Ɓ=.845, p <.001)

• Korean Journal of Child Studies
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• v.33 no.2
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• pp.129-144
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• 2012

The purpose of this study was to focus on the effects of a mother's characteristics and self-awareness as they impact upon parenting stress, with the additional aim of creating an appropriate structural equation model. The subjects of the study comprised 2078 newborn children (and their mothers) taken from the $1^{st}$ year of the Korea Children's Panel. The results of the research are as follows. The mother's feeling of pregnancy, her income activity, religion, and educational level impacted significantly upon self-awareness, whereas employment status did not. In addition, the feeling of pregnancy and income activity had a effect on parenting stress both directly and indirectly. Educational level and religion impacted on parenting stress indirectly through self-awareness. Both employment status and self-awareness were found to have impacted on parenting stress directly. The implication of these findings are also discussed.

• Journal of the Korea Convergence Society
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• v.12 no.8
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• pp.369-379
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• 2021

This study was a descriptive survey study to compare the stress, depression, fatigue, and sleep quality between pregnant women with gestational diabetes mellitus (GDM) and normal pregnant women. The study subjects were 49 gestational diabetes mellitus women and 51 normal pregnant women who were matching with gestational diabetes mellitus women by age, gestational age and number of births. The data collection was measured using structured questionnaires, numerical scales, and Canopy9 RSA(IEMBIO, Gangwondo, Korea) equipment. As a result of the study, pregnant women with gestational diabetes had higher pre-pregnancy weight(t=3.698, p<.001) and higher stress(t=4.505, p<.001), depression(t=4.564, p<.001), and fatigue(t=3.709, p<.001) during pregnancy, so weight management is important before pregnancy, and stress, fatigue, and depression relief nursing

• Journal of Nutrition and Health
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• v.41 no.8
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• pp.776-785
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• 2008

Maternal stress was one of the common symptoms that pregnant women could have experienced during pregnant period. The purpose of this study was to investigate the relation of maternal stress with maternal nutrients intake and pregnancy outcome. Subjects were 248 pregnant women and were recruited at two hospitals in Seoul area. Individual stress levels were divided by the stress scores (total 41 scores), as low stressed group (< 12) and high stressed group (${\geqq}12$). The social characteristics, nutrient intake, anthropometric measurements and pregnancy outcome were compared between low stressed group (LSG) and high stressed group (HSG) to recognize risk factor of maternal stress. We found that subjects experience stress by various factors which were concern about newborn (40.4%), concern about health (28.8%), economic difficulties (13.2%), depress (10.1%), family relationship (2.9%), concern of house work (2.5%), human relationship (2%). In HSG, unemployed rate (p < 0.05) and pre-pregnancy BMI (p < 0.05) were higher than in LSG. Family size in HSG was larger than that in LSG (p < 0.01). Doing regular exercise with the light activity level was significantly higher in LSG (p < 0.05). The nutrient intake in LSG was slightly higher than that in HSG, but not statistically significant. Pregnancy outcome was not significantly affected by the maternal stress. In conclusion, the risk of maternal stress may be related with a life style during pregnancy. Therefore, life style for maternal stress control, such as weight control and regular exercise is recommended to prevent maternal stress.