• Clinical and Experimental Pediatrics
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• 제49권6호
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• pp.593-601
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• 2006

Allergic rhinitis is a common disease of childhood characterized by nasal, throat, and ocular itching, rhinorrhea, sneezing, nasal congestion. Those affected with allergic rhinitis often suffer from associated inflammatory conditions of the mucosa, such as allergic conjunctivitis, rhinosinusitis, asthma, otitis media with effusion, and other atopic conditions, such as eczema and food allergies. Allergic rhinitis must be diagnosed and treated properly to prevent complications and impaired quality of life. Despite a high prevalence, allergic rhinitis isoften undiagnosed and inadequately treated, especially in the pediatric population. The first step in treatment is environmental control when appropriate. It may be difficult to eliminate all offending allergens effectively to reduce symptoms, so medications are often required. Many different classes of medications are now available, and they have been shown to be effective and safe in a large number of well-designed, clinical trials. Antihistamines are effective in treating immediate symptoms of sneezing, pruritus, watery eyes, and rhinorrhea. Second generation antihistamines are the preferred antihistamines because of their superior side effect profile. Thus, decongestants are commonly used with oral antihistamines. Intranasal corticosteroids are the most effective therapy for allergic rhinitis. Leukotriene modifier may be as effective as antihistamines in treating allergic rhinitis symptoms. Cromolyn sodium is an option for mild disease when used prophylactically, and ipratropium bromide is effective when rhinorrhea is the predominant symptom. When avoidance measures and medications are not effective, specific immunotherapy is an effective alternative. Only immunotherapy results in sustained changes in the immune system. Because of improved understanding of the pathogenesis, new and better therapies may be forthcoming. The effective treatment of allergic rhinitis in children will reduce symptoms and will improve overall health and quality of life, making a happier, healthier child.

• Archives of Plastic Surgery
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• 제32권2호
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• pp.183-188
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• 2005

Defect on the temporal area caused by, surgical ablation of a tumor or an infection should be reconstructed immediately to prevent potentially life-threatening complications such as meningitis and cerebrospinal fluid leakage. The defect on the temporal area usually presents as a typical 'cone-shape'. Successful reconstruction requires sufficient volume of well-vascularized soft tissue to cover the exposed bone and dura. From 1994 through 2003, the authors applied rectus abdominis free flap for the reconstruction of the temporal defect from 1994 through 2003. There were 10 patients with a mean age of 52.1 years. Of these 10 patients, external auditory canal cancer was present in four patients, temporal bone cancer in two, parotid gland cancer in one and three patients were reconstructed after debridement of infection(destructive chronic otitis media). All the free flaps survived, and flap-related complications did not occur. Compared to a local flap, the rectus abdominis free flap can provide sufficient volume of well-vascularized tissue to cover the large defect and can be well-tolerated during an adjuvant radiation therapy. The long and flat muscle can be easily molded to fit in to the 'cone-shape' temporal defect without dead space. It is also preferred because of the low donor site morbidity, a large skin island and an excellent vascular pedicle. Two-team approach without position change is possible. In conclusion, the authors think that rectus abdominis free flap should be considered as one of the most useful method for the reconstruction of a cone-shaped temporal defect.

• Journal of Microbiology and Biotechnology
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• 제27권1호
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• pp.112-121
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• 2017

Edwardsiella tarda is a gram-negative pathogenic bacterium in aquaculture that can cause hemorrhagic septicemia in fish. Many secreted proteins have already been identified as virulent factors of E. tarda. Moreover, since virulent phenotypes are based on the expression regulation of virulent genes, understanding the expression profile of virulent genes is important. A quantitative RT-PCR is one of the preferred methods for determining different gene expressions. However, this requires the selection of a stable reference gene in E. tarda, which has not yet been systematically studied. Accordingly, this study evaluated nine candidate reference genes (recA, uup, rpoB, rho, topA, gyrA, groEL, rpoD, and 16S rRNA) using the Excel-based programs BestKeeper, GeNorm, and NormFinder under different culture conditions. The results showed that 16S rRNA was more stable than the other genes at different culture growth phases. However, at the same culture time, topA was identified as the reference gene under the conditions of different strains, different culture media, and infection, whereas gyrA was identified under the condition of different temperatures. Thus, in experiments, the expression of gapA and fbaA in E. tarda was analyzed by RT-qPCR using 16S rRNA, recA, and uup as the reference genes. The results showed that 16S rRNA was the most suitable reference gene in this analysis, and that using unsuitable reference genes resulted in inaccurate results.

• Ocean and Polar Research
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• 제24권4호
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• pp.407-417
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• 2002

Species composition and abundance of zooplankton were investigated around Dokdo in the East/Japan Sea in autumn 1999 and spring 2000. Vertical and horizontal hauls of a bongo net ($300{\mu}m$ mesh size, 60cm diameter) were made to collect zooplankton sample. Surface temperature and salinity ranged from $24.2^{\circ}C\;to\;25.1^{\circ}C$, and from 32.9psu to 33.2psu in September 1999, respectively. In May 2000, surface temperatures were $13.9^{\circ}C\;and\;14.2^{\circ}C$ at stations of A1 and A8, and salinity was 34.5psu at both stations. Zooplankton community was dominated by copepods which comprised 61% (September) and 60% (May) of total numerical abundance, respectively. The next dominant groups were appendicularians (11%) and chaetognaths (9%) in September 1999, and other crustaceans (27%) and appendicularians (4%) in May 2000. The 15.7% (September) and 23.2% (May) of copepods were in the juvenile stage of copepodites. The most dominant copepods were Oncaea media (10.4%) and Clausocalanus sp. (8.2%) which preferred warm water in September. In contrast, cold-water copepods such as Pseudocalanus minutus (9.4%) and Metridia pacifica (8.0%) were dominant in May. The results of cluster analysis based on Bray-Curtis index showed that zooplankton community were classified into two groups which represented different water mass. The average abundance of zooplankton in September was 2.1 times higher than that in May, and species number of them in September outnumbered that in May by 29 species. Zooplankton community varied in associated with a characteristic of warm waters which affected marine ecosystem differently in the study area depending on seasons.

• Nutrition Research and Practice
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• 제1권2호
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• pp.150-157
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• 2007

This study analyzed Kimchi eating culture in 178 households with female middle school children located in Incheon and Seosan areas, investigated the Kimchi eating patterns of female middle school students, and also analyzed the differences in value recognition for Kimchi between mothers and their female middle school students. Results showed that 23.0% of subject households answered eat Kimchi at every meal and the main reason for eating Kimchi in most households was good for taste. Most households made their own Kimchi, and only 12.3% of households bought Kimchi. Subject households preferred hot and spicy taste (34.8%) and pleasing taste (20.2%), and 44.4% of middle school children answered as eating Kimchi at every meal, and the source for information on Kimchi was home in 51.6% and mass media in 33.7%, suggesting the lack of school education. Both mothers and their female middle school students placed high value on Kimchi for its nutritional aspect and on Kimchi from the market for its convenience. Mothers showed significantly higher value (p<0.05) on the storage aspect of Kimchi compared to their middle school students, and female middle school students showed significantly higher value (p<0.05) on the value recognition for Kimchi as an international food compared to their mothers. Also, the value for hot pepper powder was high among other additional ingredients, and both mothers and middle school students had high values for Kimchi stew among other food dishes using Kimchi, and middle school students showed higher values (p<0.001) on foreign dishes using Kimchi such as Kimchi pizza and Kimchi spaghetti compared to the mothers group. Therefore, based on these results, the development of educational programs on Kimchi is needed not only at home but also at schools, by re-emphasizing the importance of value recognition for Klmchi in our food culture.

• 인지과학
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• 제24권1호
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• pp.71-93
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• 2013

멀티태스킹은 이제 일상이 되었다. 자발적으로 하고 있던 일을 중단하고, 다른 것으로 전환하는 행동이 점점 쉬워지고 잦아지고 있다. 그러나 기존 연구에 따르면 과제전환은 대부분 인지적 비용을 야기시킬 뿐이다. 본 연구에서는 자발적 과제전환으로 인지적 이득을 얻을 수 있는지에 대해서 알아보고자 하였다. 이를 위해서 우선, 실험 1에서는 비슷한 성격의 두 과제를 할 때, 기존 연구와 마찬가지로 과제전환빈도와 수행도에 부적상관관계가 나타남을 확인하였다. 실험 2에서는 과제전환 가능 조건과 불가능 조건을 나누고, 개인의 멀티태스킹 선호도와 미디어 멀티태스킹 지수에 따라 각 과제의 수행도와 주관적 평가가 어떻게 달라지는지를 분석하였다. 실험 결과, 기존의 대부분 연구와 다르게 과제전환에서 항상 손실이 나타나는 것은 아니었다. 특히, 멀티태스킹 선호도가 높은 집단에서는 자발적 과제전환에서의 이득이 더 크게 나타났다. 기존의 과제전환 연구는 주로 손실이 발생하는 이유와, 그것을 줄이는 방법에 집중된 경향이 있었다. 그러나 본 연구는 과제전환 행동에서 발생하는 인지적 손실 뿐만 아니라 이득도 살펴보고자 하였다. 그 결과 참가자내 조건과 과제의 특성에 따라 손실과 이득이 차이 나는 것을 확인하였다.

• 한국자기학회지
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• 제11권4호
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• pp.168-172
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• 2001

Sol-gel법을 이용하여 Co$_{0.9}$Zn$_{0.1}$Fe$_2$O$_4$ 박막을 제조하였다. 성장한 박막의 구조 및 자기적 성질에 관하여 x선 회절분석기 (XRD), atomic force microscopy(AFM) 및 Auger electron spectroscopy(AES), 진동시료자화측정기 (VSM)을 이용하였다. Co-Zn 페라이트 박막의 경우, 400 $^{\circ}C$ 이상의 열처리 온도에서 단일상의 spinel 구조만을 가지고 있으며, 아무런 방향성이 없이 성장함을 나타내고 있다. 열처리 온도가 600 $^{\circ}C$ 이하에서 성장된 박막 표면의 거칠기는 3 nm 이하였으며, 형성된 입자의 크기는 약 40nm이하임을 알 수 있었다. 또한, 40$0^{\circ}C$에서 열처리한 경우 기판에서 Si이 Co-Zn 페라이트 박막내로 확산이 거의 나타나지 않았으나, 870 $^{\circ}C$에서 열처리한 경우 계면에서 기판과 박막의 상호 확산을 확인할 수 있었다. 제작한 박막은 외부 자기장의 방향과는 무관한 등방성의 자기적 특성을 보이며, 최대 보자력은 600 $^{\circ}C$에선 열처리한 자성박막이 약 1,900 Oe을 가짐을 알 수 있었다.있었다.

• KSBB Journal
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• 제28권5호
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• pp.295-302
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• 2013

Indigo is utilized in various industries including textile dyeing, cosmetics, printing and medicinal products and its reduced form, leuco-indigo, is mainly used in these process. Chemical reducing agent (sodium dithionite, sodium sulfide, etc.) is preferred to use for the formation of leucoindigo in industry. In traditional indigo fermentation process, microorganisms can participate in the reduction of indigo and thus it has been known to reduce environmental pollution and noxious byproducts. However, in fermentation method using microorganisms it is difficult to standardize large scale production process due to low yield and reproducibility. In this study, we attempted to develop the indigo reduction process using microbial flora which was isolated from naturally fermented indigo vat or deduced by metagenomic approach. From the results of library analyses of PCR-amplified 16S rRNA genes from the traditional indigo fermentation vat sample (metagenome), it was confirmed that Alkalibacteriums (71%) was distinctly dominant in population. Some strains were identified after confirming that they become pure culture in nutrient media modified slightly. Four strains were separated in this process and each strain showed obvious reducing ability toward indigo in dyeing test. It is expected that the analyzed results will provide important data for standardizing the natural fermentation of indigo and investigating the mechanism of indigo reduction.

• 한국융합학회논문지
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• 제11권1호
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• pp.131-139
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• 2020

게이머들은 현재 게임이 재미에 싫증을 느끼거나 더 재미있는 새로운 게임을 만나면 이로 전환한다. 소비자의 게임 전환 비용은 개인에 따라 다양하며 자신들의 현재 게임에 대해 만족하는 정도에 영향을 받는다. 이 연구는 현재 게임에 대한 만족 정도를 자기 결정 이론에서의 세 가지 차원의 욕구 충족 정도로 측정하며 이들이 각각 학습(learning), 연속(continuity), 그리고 매몰(sunk) 전환 비용에 어떻게 영향을 미치는 지를 분석한다. 국내 모바일 게임 사용자를 대상으로 한 설문 조사의 분석 결과, 게임 이용자들의 자율성과 관계성 충족은 학습 비용에 양의 영향을 미치고 효능성 충족은 음의 영향을 미친다. 이러한 욕구 충족과 인지적 전환 비용의 관계는 게이머의 연령과 선호하는 게임 장르에 따라서 달리 나타나며 이러한 결과를 이용함으로써 게이머들의 다양한 전환 행동을 이해할 수 있다.

• 방송공학회논문지
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• 제13권6호
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• pp.796-803
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• 2008

본 논문에서는 사용자에게 보다 실감있고, 사용자가 선호하는 다시점 3D 영상의 3D 입체감을 제공할 수 있는, 다시점 3D 동영상의 인식 깊이감을 조절하는 기법을 제안한다. 카메라 배열을 변경하는 기존의 방법들과 달리, 제안한 기법은 사용자가 요청하는 깊이 범위의 스케일링을 활용하기 위하여 영상의 깊이 데이터를 활용한다. 다시점 영상 및 해당 시점의 깊이 영상을 입력받아 각 화소의 변이로 변환하고, 각 화소의 변이를 조절함으로써 인식되는 깊이감을 조절하게 된다. 제안 방법은 다시점 카메라로부터 획득한 다시점 영상의 처리가 가능하며, 또한 2-시점 입체영상부터 다시점 영상까지 적용이 가능하다. 실험에서는 제안한 방법을 통하여 깊이감이 조절된 다시점 동영상을 다시점 3D 모니터로 시청하였을 때, 깊이감이 사용자가 선호하는 깊이에 따라서 스케일되는 것을 DSCQS(Double Stimulus Continuous Quality Scale)으로 확인하였다.