• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1097-1102
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• 2016

Background: Liver fluke infection with Opisthorchis viverrini and its associated cholangiocarcinoma constitute a serious problem in Thailand. Healthy behavior can decrease infection, therefore, the investigation of knowledge, attitude, and practice is need required in high risk areas. Objective: This study aimed to investigate the behavior and perceptions regarding liver fluke. Materials and Methods: A cross-sectional descriptive study was conducted in Chum Phuang district of Nakhon Ratchasima province, Thailand during July to November 2015. A total 80 participants who had screened with verbal screening test, stool examination, and ultrasonography, were purposive selected and completed a pre-designed questionnaire (Kruder-Richardon-20=0.80, Cronbach's alpha coefficient=0.82 and 0.79). T-test, ANOVA, and Pearson correlation test were used for analyzed data. Results: The results reveal that O. viverrini infection was 1.25%, and 3 patients had a dilated bile ducts. The participants had a high knowledge, attitude, and practice regarding liver fluke. The education, occupation, and income, were statistical significant to attitude regarding liver fluke. Nurses and television were the main sources of information regarding liver fluke, with statistical significance(p-value <0.05). Knowledge was significantly associated with attitude and practice (p-value<0.05). Conclusions: Participants had good behavior regarding liver fluke. Improvement of knowledge and attitude is influenced to practical change regarding this carcinogenic fluke. In addition, nurse and television are the main information resources for key success in increasing people perception for disease prevention and control in this area.

• 가정과삶의질연구
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• 제9권1호통권17호
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• pp.45-63
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• 1991

The purpose of this study was to develop Family Welfare Program for strengthening Family Life, especially focused on the Family Life Education. In order to perform the above research purpose, this study was organized three sections. First, conceptualizing strong family second, measurement the degree of strong family third, is about the Family Life Education. I defined that the concept of strong family is functional family that is family members(husbands & wives)perform successfully internal family functions. I measured the strong family by means of family function performance scale which is composed by 54 questionnaires. Through the survey study with the family function performance scale. I recognized the necessity of Family Life Education for strengthening family function. Family Life Education(FLE)is an educational specialty which was originated in reaction to changing social conditions, industrialization, and urbanization. It deals with the perceive inadequacies of families to cope with these changes, thereby reducing social problems involved with, and improving family life. With and assumption that the studies about FLE have not been so active in Korea, the present thesis examines the FLE in Korea : i.e., the defintion, the objectives, the scope, the approximation of family life education, and the necessity of marital education in Korea based upon the published theories of FLE in the United States of America. Also, it attemps to formulate tentative plan for the promotion of a FLE program in Korea. The concept of FLE in Korea was mainfested itn the social educational law and lifespan institutional, governmental attention. It is defined as "the family life education to enhance the quality of human life, to solve family problems, to develop and individual's potentiality, and to strengthen the family interaction." Of the FLE program, the marital education is considered one of the crucial subjects because it is the core of the family life. With this premise, FLE tries to support the healthy marital relations, subsequently helping to explore the family potentiality and to strengthen family ties. Considering the seemingly dual characteristics of the contents of marital educations, and effective expressions of mutual affection. In addition, reciprocal understanding and cooperation of the married couples to overcome the differences of value, personality, hobby, and religion, the educational methods in child rearing kids, and the effective management of home economics should be included. The objects of the FLE program are unmarried, pre-married, and married persons. For the married persons, the FLE program should be arranged in accordance with their marital status classified by the family life cycle so that they amy prevent possible family problems t each stages of the family life. Also, to prevent the problems incurred in the course of carrying out family functions, the FLE program should be provided with on the basis of a family unit, there by improving the quality of the family functions.

• Asian-Australasian Journal of Animal Sciences
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• 제26권5호
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• pp.638-645
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• 2013

Interferon-tau (IFNT) is thought to be the conceptus protein that signals maternal recognition of pregnancy in ruminants. We and others have observed that OCT4 expression persists in the trophectoderm of ruminants; thus, both CDX2 and OCT4 coexist during the early stages of conceptus development. The aim of this study was to examine the effect of CDX2 and OCT4 on IFNT gene transcription when evaluated with other transcription factors. Human choriocarcinoma JEG-3 cells were cotransfected with an ovine IFNT (-654-bp)-luciferase reporter (-654-IFNT-Luc) construct and several transcription factor expression plasmids. Cotransfection of the reporter construct with Cdx2, Ets2 and Jun increased transcription of -654-IFNT-Luc by about 12-fold compared with transfection of the construct alone. When cells were initially transfected with Oct4 (0 h) followed by transfection with Cdx2, Ets2 and/or Jun 24 h later, the expression of -654-IFNT-Luc was reduced to control levels. OCT4 also inhibited the stimulatory activity of CDX2 alone, but not when CDX2 was combined with JUN and/or ETS2. Thus, when combined with the other transcription factors, OCT4 exhibited little inhibitory activity towards CDX2. An inhibitor of the transcriptional coactivator CREB binding protein (CREBBP), 12S E1A, reduced CDX2/ETS2/JUN stimulated -654-IFNT-Luc expression by about 40%, indicating that the formation of an appropriate transcription factor complex is required for maximum expression. In conclusion, the presence of OCT4 may initially minimize IFNT expression; however, as elongation proceeds, the increasing expression of CDX2 and formation of the transcription complex leads to greatly increased IFNT expression, resulting in pregnancy establishment in ruminants.

• 한국응용과학기술학회지
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• 제37권5호
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• pp.1171-1179
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• 2020

본 연구는 푸드표현활동 프로그램이 노인의 주관적 기억력, 우울, 자기표현에 미치는 효과를 파악하기 위한 단일집단 사전사후 원시실험연구이다. 연구방법은 S시에 위치한 2곳의 경로당 이용 노인 대상자 36명이 참여하였으며, 2020년 1월 8일부터 2월 17일까지 총 6회기 프로그램을 시행하였다. 프로그램 전후에 주관적 기억감퇴, 우울, 자기표현의 변화를 설문지로 조사하였다. 중재 프로그램은 신체적 이완활동, 인지활동 및 다양한 '푸드'를 이용하여 손의 움직임과 자기표현을 할 수 있게 구성하였다. 연구결과, 푸드표현활동 프로그램은 대상자의 주관적 기억력(t=2.67, p=.011), 우울(t=3.88, p<.001), 자기표현(t=2.09, p=.044)을 통계적으로 유의한 차이가 나타났다. 본 연구 결과를 바탕으로 푸드표현활동 프로그램은 경로당 이용 노인의 우울 감소와 기억력 및 자기표현을 향상을 위한 간호중재로 활용될 수 있을 것으로 기대된다.

• Journal of Korean Neurosurgical Society
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• 제46권2호
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• pp.87-92
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• 2009

Objective: Chronic subdural hematoma (CSDH) is one of the most common types of traumatic intracranial hemorrhage, usually occurring in the older patients, with a good surgical prognosis. Burr hole craniostomy is the most frequently used neurosurgical treatment of CSDH. However, there have been only few studies to assess the role of the number of burr holes in respect to recurrence rates. The aim of this study is to compare the postoperative recurrence rates between one and two burr craniostomy with closed-system drainage for CSDH. Methods: From January 2002 to December 2006, 180 consecutive patients who were treated with burr hole craniostomy with closed-system drainage for the symptomatic CSDH were enrolled. Pre- and post-operative computed tomography (CT) scans and/or magnetic resonance imaging (MRI) were used for radiological evaluation. The number of burr hole was decided by neurosurgeon's preference and was usually made on the maximum width of hematoma. The patients were followed with clinical symptoms or signs and CT scans. All the drainage catheters were maintained below the head level and removed after CT scans showing satisfactory evacuation. All patients were followed-up for at least 1 month after discharge. Results: Out of 180 patients, 51 patients were treated with one burr hole, whereas 129 were treated with two burr holes. The overall postoperative recurrence rate was 5.6% (n = 10/180) in our study. One of 51 patients (2.0%) operated on with one burr hole recurred, whereas 9 of 129 patients (7.0%) evacuated by two burr holes recurred. Although the number of burr hole in this study is not statistically associated with postoperative recurrence rate (p> 0.05), CSDH treated with two burr holes showed somewhat higher recurrence rates. Conclusion: In agreement with previous studies, burr hole craniostomy with closed drainage achieved a good surgical prognosis as a treatment of CSDH in this study. Results of our study indicate that burr hole craniostomy with one burr hole would be sufficient to evacuate CSDH with lower recurrence rate.

• 대한간호학회지
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• 제30권2호
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• pp.452-462
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• 2000

There are currently 214 orphanages in Korea which house approximately 13,873 orphans aged between 3 and 18; this accounts for about 0.12% of all children in the same age range. Some have lost their parents, but most have come after their parents divorced or broke up. This means majority of the children in Child Care Centers have parents. Traditional virtue of obedience to parents (Hyo) was regarded as one of the highest value in Korea. Also the interaction between parents and their children was regarded as basic human nature that parents look after, both physically and spiritually, their children until they become one of the matured social member. Raised without having a chance to realize their filial duty and not having been cared for by their parents, most orphans feel that they lack something in their lives when compared with friends. In the end, they live their lives longing for their parents and go through mental discord about their parents. This paper is focused on understanding orphans' experience and views on parents. I approached the issue by applying van Manen's Hermeneutic Phenomenological Approach. The interviews, along with other reference material were phenomenologically reflected to draw essential themes as follows; 1. Orphans of pre-school age hazily long for parents without having any practical image of their parents. 2. They occasionally dream meeting their parents with image that can only last in their dreams, and this continues up through middle school. 3. At the age of elementary school, they crave the image of parents as they see their friends with their parents. 4. They start to despise their parents for having abandoned them when they reach puberty. 5. Meanwhile, as their vague image of parents fade away, they attempt to give up their thoughts toward their parents. 6. Highteens start to think in terms of fate. 7. They don't long for their parents anymore as they used to, but still wishes to meet them at least once. However, they don't want to start any kind of a relationship with them. 8. They fear that they will also fail in raising families of their own, and making their children orphans too, just like their parents have. They simply don't want to follow their footsteps. 9. Thinking that they were abandoned by their parents, they are reluctant to believe other people.

• 한국재료학회지
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• 제8권3호
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• pp.268-273
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• 1998

Zircaloy-4 합금판재에 230-250ppm의 수소를 장입시키고 $400^{\circ}C$에서 72시간동안 균질하게 수소화물을 형성시킨후 $350^{\circ}C$의 static autoclave를 이용하여 여러 가지 농도의 LiOH 부식용액조건에서 부식시험을 수행하였다. 부식평가는 시간에 따른 무게증가의 변화로서 측정하였고, 시편의 미세구조는 광학현미경과 주사전자현미경을 사용하여 관찰하였다. 부식시험 후 형성된 산화막에서의 H와 Li의 분포를 확인하기 위해 secondary ion mass spectrometry(SIMS)를 이용해 각 원소의 분포를 두께방향에서 측정하였다. 여러 가지 농도의 LiOH 수용액조건에서 Li+ 이온의 용액농도가 30ppm 이상으로 증가하면 합금의 부식은 급격히 가속화되었다. 이것은 $Li^{+}$가 산화막 내의 $Zr^{4+}$ 자리를 치환함에 따라 산소공공이 증가로 산화반응이 증가되고, 이로 인해 형성되는 수소화물의 양이 증가하기 때문이다. LiOH용액조건에서 부식시험 전에 시편 내에 수소를 장입시켜 수소화물을 형성시키면 수소를 장입하지 않은 시편보다 부식이 더 빨리 가속되지만, 시험기간이 길어지면 오히려 수소를 미리 장입시키지 않은 시편의 부식속도가 더 빨라진다. 이것은 부식시험 전에 수소를 시편에 미리 장입을 시키면 이때 형성된 수소화물에 의해 초기에 부식이 빨리 가속되지만 이미 고용도 이상의 수소가 금속 내부에 존재하므로 부식과정 중에 생기는 수소가 금속의 내부로 확산되어 들어오는 것이 억제되어 부식속도가 둔화되는 것으로 생각된다.

• 아태비즈니스연구
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• 제2권1호
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• pp.91-114
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• 2011

일본 전체 전자상거래 시장 규모는 2006년에 15조엔을 넘었고, 2009년에 B2C 인터넷 쇼핑 규모는 6조 5,700억엔을 넘는 등 지속적으로 확대되고 있다. 일본의 대표적인 인터넷 쇼핑 업체로는 락쿠텐을 들 수 있다. 락쿠텐은 인터넷 쇼핑 시장에서 45%의 점유율을 보이고 있고, 등록된 상점 수만 7만개가 넘는다. 사이트내의 과장 광고에 대한 규제 및 판매자에 대한 철저한 사전 통제로 소비자들의 높은 신뢰를 받고 있다. 일본 소비자들은 새로운 기술에 대한 수용과 동화가 빠른 편이고, 인터넷과 모바일 통신 사용률이 높다. 본 논문에서는 우리의 이웃이면서 큰 인터넷 쇼핑 시장이 있는 일본의 온라인 쇼핑 실태에 대해서 분석하였다. 즉, 인터넷 쇼핑 동기, 인터넷 쇼핑 지각 위험, 인터넷 쇼핑 혁신성 등에 따른 인터넷 쇼핑 이용의도, 만족도, 추천의도 등과 인구통계학적 특성을 고려해 살펴보았다. 총 464부 설문지에 대해 SPSS를 활용하여 빈도분석, 요인분석, 신뢰도 분석, 분산분석 등이 이루어졌다. 분석 결과 이용의도는 연령이 높을수록 높았고, 만족도는 주부가, 추천의도는 월 평균 소득이 높을수록 높았다. 또한 혁신성이 높은 집단일수록 이용 빈도, 만족도, 추천의도, 지속 사용의도가 높았다. 인터넷 쇼핑 동기와 관련해서는 여성과 주부의 쾌락적 동기가 높았고, 월 평균 소득이 높을수록 경제적 동기가 높았다. 또한 혁신성이 높은 집단이 경제적, 편의적, 쾌락적, 사회적 인터넷 쇼핑 동기 모두 높은 평균값을 보였다. 또한 학생일수록, 여성일수록, 소득수준이 낮을수록 인터넷 쇼핑 지각된 위험을 높게 평가하는 것으로 나타났으며 혁신성 정도가 낮은 집단이 역시 지각된 위험을 높게 평가하였다. 끝으로 본 연구 결과를 바탕으로 향후 일본 전자상거래에 진출하고자 하는 우리나라 기업에 실무적인 시사점을 제시하였다.

• 한국산학기술학회논문지
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• 제15권3호
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• pp.1448-1457
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• 2014

평균수명이 연장되면서 노인인구비율 증가와 함께 각종 노인성 질환이 증가하고 있다. 노인성 질환을 대상으로 한약재를 이용한 치료적 접근위주의 연구는 시도되고 있으나, 건강관리 차원에서 예방적 접근방법으로 한방건강 음료로서의 한방차에 대한 연구는 미미한 실정이다. 본 연구는 노인요양시설을 이용하는 노인을 대상으로 한방차의 섭취가 생리적 기능과 행동변화에 미치는 효과를 확인하기 위한 비동등성 대조군 전후 설계의 유사 실험연구이다. 대상자는 실험군 20명, 대조군 18명으로 총 38명이었다. 2013년 5월부터 6월까지 1회 100ml씩, 일 3회, 30일간 본 연구에서 개발한 한방차를 적용하였고, 양자분석기로 생리적 기능을, 구조화된 설문지로 행동변화를 측정하였다. 수집된 자료는 SPSS/WIN 18.0 프로그램을 이용하여 분석하였다. 분석 결과 실험군에서 생리적 기능 중 혈류순환(t=-4.466, p<.001), 간기능(t=-2.855, p=.007), 뇌기능(t=-2.545, p=.015), 골밀도(t=-6.125, p<.001), 혈당(t=-4.180, p=<.001)과 행동변화의 하위지수인 정서적 요인(t=2.389, p=.023)에서 유의한 변화가 나타났다. 따라서 노인의 생리적 기능 향상과 정서적 안정에 긍정적인 효과가 나타난 한방차의 음용은 노인요양시설에서 노인 건강을 위한 효과적인 중재 방법으로 활용될 수 있다고 사료된다.

• The Korean Journal of Pain
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• 제7권2호
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• pp.162-169
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• 1994

Blockade of cervicothoracic sympathetic ganglion (stellate ganglion controls pain on face, head, neck, shoulder, upper limbs, and upper chest, including their viscera and sympathetically maintained pain. This procedure also increases blood flow to the above areas and relieves hyperreactivity of sympathetic nervous system. Clinically, repeated stellate ganglion blocks with local anesthetic agent may become difficult with complications such as accidental intravascular or subdural injection, recurrent laryngeal nerve or bracheal plexus paralysis, pneumothorax and edema on injection site. Therefore, at times long-term cervicothoracic ganglion block with neurolytics is necessitated but its applications are prohibited by the critical structures surrounding ganglion. There are also few reports of neurolytic stellate ganglion block. This study was performed to observe the complications, gross changes of surrounding structures, and microscopic findings of ganglion cells after neurolytic block and to certify the possibility of clinical use of neruolytic stellate ganglion block. The unilateral superior cervical sympathetic ganglion of rabbit was blocked with absolute ethyl alcohol 0.4 ml at the level of cricoid cartilage. Normal ganglion was used as a control and 5 animals were sacrificed at each intervals of 7, 15 and 50 days after block. The results were as follows; 1) All experimental animals showed no specific changes of behavior, motor function. No necrotic tissues were present in the block area during the observation period. There were some gross scar tissues along the fascia of muscles surrounding the needle injection site, but gross atrophy of muscles or injured major vessels were not found. 2) Microscopically, structures of normal ganglion of rabbit were very similar to those of humans. Seven days after absolute ethyl achohol injection there were marked edema of ganglion cells and nuclei with irregular nuclear membrane. Some of the ganglion cells lost their nuclei and showed degenerative changes. Fifteen days after block, cell edema were decreased and loss of the Nissl's body was prominant. The ganglion cell structures looked close to normal but the cytoplasm and nucleus were generally contracted 50 days after block. These results suggest absolute ethyl alcohol injection on cervical sympathetic ganglion with above method mainly blocks pre- and post-synaptic fibers and the long-term neurolytic blockade of this ganglion may be possible in rabbits.