• 동의신경정신과학회지
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• 제18권3호
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• pp.209-224
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• 2007

Metabolic syndrome consists of several risk factors of metabolic origin like elevated blood pressure, abdominal obesity, elevated triglyceride concentrations, decreased HDL-cholesterol concentrations, and elevated fasting glucose. It appear to directly increase the development of atherosclerotic cardiovascular diseases which leading to cardiovascular diseases in later life. This 39 years female patient was diagnosed schizophrenia at the age of 17. but she didn't take reasonable treatments. during 20 years, she stayed in home and lived unsuited life with her family. As a result she gains heavy weight and centeral obesity, diabetic mellitus and hypertention, and developed cerevral vascular accident twice. This patient was treated with herb medication, acupuncture, western medication, psychotherapy primarily in focusing of pre-illness state(未病) as well as the stagnation of phelm. During 140 days of treatment from admission, before 2nd attack tbe patient showed improvement of Lt. hemiparesis but after second attack improved a little. And symptom of schizophrenia improved considerably. Also diet habit changed.

• 한국정보통신학회논문지
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• 제19권11호
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• pp.2590-2596
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• 2015

메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 기회를 제공하는 통계적 통합 방법이다. 우리나라 학술지에 게재된 대사증후군 위험요인에 관한 연구들을 계량적으로 통합하고 검토해보기 위해 진행하였다. 본 연구는 대사증후군에 대한 문헌적 고찰을 통해 선행연구를 살펴보고 열거된 요인에 관한 실증 분석된 연구들을 메타분석 하기 위해 2000년-2015년 국내 학술지에 게재된 36편 논문을 연구대상으로 하였다. 메타분석 결과 허리둘레 사전 사후 경로에서 가장 큰 효과 크기(r = .420)인 것으로 나타났다. 두 번째 큰 효과 크기는 고밀도지단백콜레스테롤 사전 사후 경로(r = -.402)인 것으로 나타났다. 그런데 이완기 혈압 사전 사후 경로가 가장 작은효과 크기(r = .234)인 값을 확인할 수 있었다. 따라서 연구결과를 바탕으로 학문적 실무적 의의를 논의하였다.

• 한국산학기술학회논문지
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• 제19권12호
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• pp.170-177
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• 2018

본 연구의 목적은 12주간 순환운동이 비만중년여성의 건강 체력 및 대사증후군 위험인자에 미치는 영향을 알아보기 위하여 실시하였다. $BMI\;25kg/m^2$ 이상인 40대 비만중년여성 중 순환운동군(10명), 대조군(10명)으로 총 20명을 대상으로 실시하였으며, 모든 검사항목은 동일한 방법과 조건으로 건강 체력 및 대사증후군 관련인자 대하여 사전, 사후 총 2회 측정하였다. 순환운동은 12주간, 주3회, 30~40분, 60~80%HRR 강도로 실시하였다. 측정변인에 대해 평균값과 표준편차($M{\pm}SD$)를 산출한 후 사전 운동군과 대조군의 신체적 특성과 각 측정변인에 대한 동질성 검정을 위하여 독립 t-test를, 집단 내의 사전 사후 평균치 변화에 대한 차이 검증은 종속 t-test를, 집단 간 차이에 대한 주효과 검정 및 집단 간 시기 간 상호작용 효과는 반복측정 분산분석을 이용하였다. 건강 체력에서 체지방률(p<.01)은 유의하게 감소하였으며, 제지방량(p<.05), 근지구력(p<.01), 유연성(p<.01) 및 심폐지구력(p<.001)은 유의하게 증가하였다. 대사증후군 위험인자 중 허리둘레(p<.05), SBP(p<.05), Glucose(p<.05) 및 TG(p<.001)는 유의하게 감소하였으며, HDL-C(p<.001)는 유의하게 증가하였다. 순환운동이 비만중년여성의 건강 체력 및 대사증후군 위험인자의 개선에 도움을 줄 수 있을 것으로 사료된다.

• 동의생리병리학회지
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• 제22권6호
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• pp.1626-1632
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• 2008

Among patients who are receiving treatments at an oriental medical hospital for various symptoms and diseases, patients whose main disease is accompanied by metabolic syndrome with abnormal liver function. This research was performed in order to observe the progression of changes in the liver function and serum lipid profile after the oriental medical treatments to patients who have been receiving oriental medical treatment for various other diseases and have been diagnosed as having metabolic syndrome at their first visit to the hospital based on NCEP ATP III diagnosis criteria and WHO Asia Pacific region criteria. Total number of subject patients were 39cases(mean age:55.58${\pm}$2.09 years) which had 20 male and 19 female. For the references for hepatic enzyme levels and blood lipid profile were measured in before treatment and four times after treatments(every 2.31${\pm}$06.17 weeks). Serum AST was 48.86${\pm}$7.46 IU/L before oriental medical treatment. After the treatment, 40.63${\pm}$4.69, 43.12${\pm}$5.46, 37.82${\pm}$4.52 IU/L were measured where although the level decreased to the normal level compared to pre-treatment, the value was not significant statistically(P>0.05). ALT was 66.26${\pm}$11.01 IU/L before oriental medical treatment. After the treatment 62.10${\pm}$8.20, 61.10${\pm}$8.76, 43.79${\pm}$5.68 were measured where although the level decreased, abnormally high level was maintained. The last result was significant statistically(P<0.05) compared to pre-treatment. ALP was 193.06${\pm}$14.20 IU/L before oriental medical treatment. After the treatment, 176.80${\pm}$6.48, 177.46${\pm}$11.81, 162.41${\pm}$9.06 where although compared to pre-treatment the last result was significant statistically(P<0.05), the change was within the normal range. ${\gamma}$-GGT was 87.83${\pm}$12.59 IU/L before oriental medical treatment. After the treatment, progressively near normal level was achieved with 118.73${\pm}$46.45, 85.03${\pm}$17.12, 70.64${\pm}$10.93 and the last result was statistically significant compared to pre-treatment (P<0.05). Blood triglyceride was 217.63${\pm}$32.18 mg/dL before oriental medical treatment. After treatment 215.09${\pm}$22.18, 189.93${\pm}$22.44, 191.22${\pm}$18.51 where abnormal values continued even after treatment although results was not statistically significant compared to pre-treatment(P>0.05). Total-cholesterol was 197.28${\pm}$9.24 mg/dL before oriental medical treatment, after treatment 201.55${\pm}$11.13, 186.87${\pm}$8.77 and 186.68${\pm}$7.61 were measured that results were not statistically significant compared to pre-treatment(P>0.05). HDL-cholesterol was 41.88${\pm}$2.38 mg/dL before oriental medical treatment, after treatment 48.75${\pm}$4.22, 44.10${\pm}$1.91, 48.00${\pm}$2.06 the results were not statistically significant compared to pre-treatment(P>0.05). LDL-cholesterol was 111.66${\pm}$13.08 mg/dL before oriental medical treatment, after treatment 109.94${\pm}$10.18, 101.79${\pm}$8.63, 104.00${\pm}$6.98 the results were not statistically significant compared to pre-treatment(P>0.05). With such results, even if common oriental medical treatments were given to metabolic syndrome patients with abnormal liver function, the liver function was confirmed not to be aggravated, and the concentration of lipids in the blood was confirmed not to be affected in most patients.

• 한국정보통신학회논문지
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• 제20권6호
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• pp.1074-1080
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• 2016

빅데이터 분석은 기존 데이터베이스 관리 도구로부터 데이터를 수집, 저장, 관리, 분석할 수 있는 역량을 말한다. 따라서 메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 수 있는 기회를 제공하는 통계적 통합 방법이다. 일반적으로 대사증후군 위험요인을 허리둘레, 수축기혈압, 이완기혈압, 공복혈당, 중성지방 그리고 고밀도지단백콜레스테롤 요인으로 정의한다. 메타분석 결과 공복혈당 사전 사후 경로에서 가장 큰 효과크기(r = -.324)인 것으로 나타났다. 따라서 콩 식품의 중재효과는 10%의 설명력을 확인할 수 있었다. 두 번째 큰 효과크기는 허리둘레 사전 사후 경로(r = .256)인 것으로 나타났다. 그런데 콩 식품의 습취는 허리둘레 (복부비만) 개선효과가 없는 것을 확인할 수 있었다. 이러한 결과를 바탕으로 학문적 실무적 의의를 논의하였다.

• 한국조리학회지
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• 제23권8호
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• pp.184-194
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• 2017

The purpose of this study was to investigate the relationship between coffee intake and metabolic syndrome, which has increased the burden of social illness, based on the data of the $6^{th}$ National Health and Nutrition Survey in 2015. The subjects' coffee intake level was divided into <1 cup/a day, 1~2 cups/a day, and ${\geq}3cups/a\;day$ and the general characteristics of the subjects were examined according to the classification. The effect of coffee consumption on the risk factors of metabolic syndrome was evaluated by OR value. The age of the subjects was higher than that of the other groups in the < 1 cup/day group and the TG in the prediabetic group was above the normal level in the ${\geq}3cups/day$ group. In the normal group of blood glucose, coffee intake was the highest in <1 cup/day group and BP was significantly different according to intake. In the multiple regression analysis conducted to identify the causal relationship between the risk of metabolic syndrome and coffee intake, BP was significantly decreased in ${\geq}3cups/day$ coffee group in normal group. In order to control the level of blood lipids in pre-diabetic subjects, it is necessary to establish dietary guidelines for foods that are frequently consumed, and various situations and long-term studies are needed to determine the precise effect of coffee intake on BP.

• 한국노년학
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• 제29권4호
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• pp.1397-1411
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• 2009

본 연구는 고령여성을 대상으로 간헐적인 걷기의 반복을 통해 신체활동량을 축적시켜 건강관련체력과 대사증후군 위험요인에 미치는 영향을 살펴보고자 시도하였다. 이를 위해 규칙적인 운동경험이 없는 65세 이상의 여성 자원자 총45명을 대상으로 간헐적 걷기집단, 지속적 걷기 집단, 통제집단의 세 집단으로 각각 15명씩 무작위 배정하였다. 간헐적 걷기집단은 매회 10분의 걷기를 4시간 간격으로 하루 3회 실시하고 지속적 걷기집단은 1일 1회 30분의 지속적인 걷기를 실시하였으며, 두 집단 모두 주 3회의 빈도로 12주간 실시하였다. 12주의 걷기 프로그램 종료 후 건강관련체력 측정결과 두 집단 모두 신체조성, 근지구력, 유연성, 전신지구력 항목에서 유의한 변화가 관찰되었으며, 근력에서는 지속적 걷기집단에서만 유의한 변화가 나타났다. 대사증후군 위험요인의 분석결과에서는 이완기혈압을 제외한 수축기혈압, 중성지방, 고밀도 지단백, 혈당에서 걷기를 실시한 두 집단 모두 긍정적인 개선효과가 나타났다. 결론적으로 매회 10분의 걷기를 하루 3회 실시하여 30분의 신체활동시간을 축적한 결과 30분간 지속적으로 걷기를 실시했을 때 나타나는 유산소 운동의 긍정적인 효과와 유사한 결과가 나타났으며, 체력수준이 약한 고령여성의 신체활동 증가를 위한 실용적이며 효율적인 운동방법으로 추천될 수 있을 것이다.

• 한국산업보건학회지
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• 제34권1호
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• pp.77-84
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• 2024

Objectives: Interventions promoting physical exercise and healthy habits in workplaces have been shown to be effective in reducing risk factors for metabolic syndrome. This study was conducted to examine the effects of an individualized conditioning exercise program of IT company office workers with or at higher risk of metabolic syndrome. Methods: A total of 444 IT company office workers with or at higher risk of metabolic syndrome participated in a 3-month conditioning exercise program. Body composition data using bioelectrical impedance analysis and cardiopulmonary data using cardiopulmonary exercise testing from 53 individuals (mean age: 34.8 ± 7.1 years, sex : 21% female, height : 170.4 ± 6.8 cm, weight : 75.2±12.2 kg, body mass index : 25.8±3.3 kg/m²) who have successfully completed pre-test, intervention, and post-test were analyzed. The 12 weeks intervention encompassed: (1) health counseling (2) supervised exercise(endurance-based, aerobic exercise, or circuit training once a week for 50 minutes at heart rate reserve(HRR) of 77-95%) (3) self-directed exercise and biweekly health screening checks. Results: The results indicated a significant decrease in body weight, body fat mass and body mass index, respectively. Moreover, VO₂peak, AT VO₂ and AT Time significantly improved, respectively. Resting blood pressure(SBP/DBP) showed positive changes but were not statistically significant. We observed the correlation between characteristics of participants and rate of changes in cardiopulmonary outcomes of participants, there are no significant correlation. These results indicate positive changes in body composition and cardiorespiratory fitness parameters following individualized conditioning exercise program. Conclusions: Individualized workplace exercise program for preventing metabolic syndrome can lead to improvements in body composition and cardiorespiratory fitness.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2015년도 추계학술대회
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• pp.143-146
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• 2015

메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 수 있는 기회를 제공하는 통계적 통합 방법이다. 우리나라 학술지에 게재된 대사증후군과 비만 위험요인에 관한 연구들을 계량적으로 통합하고 검토해보기 위해 진행하였다. 본 연구는 대사증후군과 비만에 대한 문헌적 고찰을 통해 선행연구를 살펴보고 열거된 요인에 관한 실증 분석된 연구들을 메타분석하기 위해 2000년-2015년 국내 학술지에 게재된 논문을 연구대상으로 하였다. 국내 학술지에 게재된 논문만 여과하여 조건에 부합한 총 36편의 논문을 연구에 대상으로 선정하였다. 메타분석 결과 허리둘레(복부비만) 사전사후 경로에서 가장 큰 효과크기(r = .420)인 것으로 나타났다. 두 번째 큰 효과 크기는 고밀도지단백콜레스테롤 사전사후 경로(r = -.402)인 것으로 나타났다. 그런데, 이완기혈압 사전사후 경로가 가장 작은 효과크기(r = .234)인 값을 확인할 수 있었다. 따라서 이러한 연구결과를 바탕으로 학문적 실무적 의의를 논의하고자 한다.

• 동의생리병리학회지
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• 제23권2호
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• pp.512-519
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• 2009

Among patients who visited each clinical department for oriental medical treatments, anthropometric measurement, blood pressure, fasting blood glucose and blood lipid profile level were measured at their first initial visit. 55 subject patients who were diagnosed as having metabolic syndrome and 150 mg/dL or more of triglyceride were selected as subjects whose fasting blood glucose, triglyceride, total cholesterol, HDL cholesterol and LDL cholesterol were measured after fasting. According to each patient's disease, the subject received treatments such as herb medicine, acupuncture, moxibustion, cupping therapy, physical therapy and rehabilitation therapy from each clinical department, and after an average of 4.10${\pm}$0.31 weeks, another test was performed yielding the following results. Serum triglyceride was 243.72${\pm}$13.05 mg/dL before the oriental medical treatment and 188.11${\pm}$12.17 mg/dL after the treatment where although it continued to show an abnormal value even after the treatment, there was statistically significant decrease compared to pre treatment(P<0.05). Serum total cholesterol was 207.50${\pm}$5.89 mg/dL before the oriental medical treatment and 192.37${\pm}$5.53 mg/dL after the treatment which was statistically insignificant compared to pre treatment(P>0.05). Serum HDL cholesterol was 51.19${\pm}$3.95 mg/dL before the oriental medical treatment and increased to 52.53${\pm}$1.49 mg/dL after the treatment although it was statistically insignificant compared to pre treatment(P>0.05). Serum LDL cholesterol was 110.66${\pm}$5.86 mg/dL before the oriental medical treatment and decreased to 106.12${\pm}$4.82 mg/dL after the treatment although it was statistically insignificant compared to pre treatment(P>0.05). In regards to the change of triglyceride for each sex, it was 221.84${\pm}$14.01 mg/dL before the treatment and 187.00${\pm}$15.47 mg/dL after the treatment for men, and it was 271.50${\pm}$22.78 mg/dL and 189.53${\pm}$19.76 mg/dL respectively for women where even though men and women showed the decrease of 34.84${\pm}$12.79 mg/dL and 81.96${\pm}$20.01 mg/dL respectively, both men and women continue to show abnormal values after the treatments. However, there was statistically significant decrease compared to pre treatment(P<0.05). In regards to the change of total cholesterol for each sex, with 198.24${\pm}$7.60 mg/dL for men before the treatment and 188.93${\pm}$7.45 mg/dL after the treatment, values for both before and after the treatment were within the normal range where the change value was 9.30${\pm}$5.86 mg/dL and statistically insignificant(P>0.05). For women, it was 219.26${\pm}$8.87 mg/dL and 196.73${\pm}$8.43 mg/dL respectively for women where with 22.53${\pm}$7.60 mg/dL, it decreased to the normal level after the treatment, and there was a statistically significant decrease compared to pre treatment(P<0.05). With such results, serum triglyceride and cholesterol levels of patients who have been diagnosed as having metabolic syndrome were observed to decrease after the oriental medical treatment. Especially, for both men and women, abnormally high triglyceride level decreased while the effect of lipid profile improvement for women was more significant compared to men.