• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.361-365
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• 2012

Aims: To investigate the relationship between the expression of ${\beta}$-tubulin III and survivin in advanced breast cancers and chemotherapeutic effects of docetaxel. Methods: Clinical pathological data of 74 patients with advanced breast cancer were retrospectively analyzed after docetaxel chemotherapy. Expression of ${\beta}$-tubulin III and survivin was assessed by immunohistochemistry and analyzed with reference to therapeutical and adverse effects of docetaxel. Results: The positive expression rate of ${\beta}$-tubulin III was 38.1% (32/84), while that of survivin was 76.2% (64/84). The effective rate (complete response + partial response) was 52.4%. That for patients with the positive expression of ${\beta}$-tubulin III or/and survivin was significantly lower than for those with negative expression (P<0.05). There were significant differences in the non-progression of median diseases, 1-year and 2-year survival rates of between the patients with positive and negative expression (P<0.05). The main side effects were myelosuppression, alimentary canal response and alopecie, no differences being observed between groups. Conclusions: The combined detection of ${\beta}$-tubulin III and survivin is a predictive index for chemotherapy effects of docetaxel in metastatic breast cancer.

• The Korean Journal of Pain
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• 제14권2호
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• pp.199-206
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• 2001

Background: The lumbar sympathetic ganglia are variable in both position and numbers. The aim of this study was to detect the appropriate lumbar vertebral level where the lumbar sympathetic ganglia primarily aggregate. Methods: Forty patients comprising of hyperhidrosis (26 cases), complex regional pain syndrome (10 cases), peripheral artery occlusion disease (3 cases) and postherpetic neuralgia (1 case) underwent lumbar sympathetic block. We randomly selected one of two (L2 or L3) levels and the L4 level. The position of the needle tip and distribution of dye was verified by injection of a mixture of radio-opaque dye (1.5 ml) and 4% lidocaine (1.5 ml) and subsequently confirmed by L-spine anteroposterior and a lateral view X-ray. We considered the response positive when the skin temperature increased more than $1^{\circ}C$ in 5 min. Results: In general, the positive response ratio was greater when the needle tip located at the L2 or L4 level vice L3 and when the drug was distributed on the lower half of the L4 body and in the L4/5 intervertebral disc space. In a right side block, the positive response ratio was greater when the drug was distributed on the lower half of the L4 body and in the L4/5 intervertebral disc space, although in a left side block there was no significant difference seen between the levels. The complications of the neurolytic block were alcohol neuritis (7.5%) and hypoesthesia (5%) on the L1 or L2 dermatome. Conclusions: The best effect with least chance of complication may be induced by spreading the drug on the lower half of the L4 body and/or into the L4/5 intervertebral disc space by placing the needle tip on the L4 body.

• 한국유통학회지:유통연구
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• 제6권2호
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• pp.65-89
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• 2002

타협(compromise)은 상호 양보(concession)에 의해 갈등을 해결하는 방법으로, 타협행태는 일방의 양보에 상대방도 양보하는 긍정적 대응, 일방의 요구(demand)에 상대방도 요구로 맞서는 부정적 대응, 그리고 일방의 양보나 요구에 요구나 양보로 응하는 비대응의 세 가지로 분류된다. 그리고 제조업자가 유통업자와의 갈등을 타협(compromise)으로 해결하고자 할 때 그 제조업자가 처할 수 있는 하나의 상황이 전제된다. 이 상황적 전제 하에 하나의 이론적 틀이 제시된다. 먼저 이 이론적 틀은 제조업자와 유통업자 간의 타협이 긍정적 대응양식으로 성사되는데 영향을 미치는 주요 변수들을 제시한다. 다음으로, 긍정적 대응양식의 타협이 제조업자와의 관계에 대해 유통업자가 갖는 몰입(commitment to relationship)에 미치는 영향을 설명한다. 이 이론적 틀로부터 17개의 제언들(propositions)이 도출되며, 이 제언들이 시사하는 갈등해결전략도 논의된다.

• 천문학회보
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• 제37권2호
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• pp.116.1-116.1
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• 2012

When an interplanetary (IP) shock passes over the Earth's magnetosphere, the geosynchronous magnetic field strength near the noon is always enhanced, while the geosynchronous magnetic field near the midnight decreases or increases. In order to understand what determines the positive or negative magnetic field response at nightside geosynchronous orbit to sudden increases in the solar wind dynamic pressure, we have examined 120 IP shock-associated sudden commencements (SC) using magnetic field data from the GOES spacecraft near the midnight (MLT = 2200~0200) and found the following magnetic field perturbation characteristics. (1) There is a strong seasonal dependence of geosynchronous magnetic field perturbations during the passage of IP shocks. That is, the SC-associated geosynchronous magnetic field near the midnight increases (a positive response) in summer and decreases (a negative response) in winter. (2) These field perturbations are dominated by the radial magnetic field component rather than the north-south magnetic field component at nightside geosynchronous orbit. (3) The magnetic elevation angles corresponding to positive and negative responses decrease and increase, respectively. These field perturbation properties can be explained by the location of the cross-tail current enhancement during SC interval with respect to geosynchronous spacecraft position.

• Asia Marketing Journal
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• 제9권3호
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• pp.75-115
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• 2007

본 연구는 고객이 서비스 실패와 복구를 경험하는 과정에서 서비스 제공자의 서비스 복구노력과 서비스 실패 이전의 고객-종업원의 친밀감이 만족, 재구매의도, 긍정 구전에 미치는 영향을 고찰하였다. 첫째, 본 연구는 서비스 실패와 복구 후 소비자의 반응에 대한 서비스 제공자의 복구노력과 친밀감의 상호작용효과를 검증하였다. 실험결과 서비스 실패 이전 고객과 종업원의 친밀도가 높은 집단에서는 친밀도가 낮은 집단에 비하여 서비스 실패후의 복구노력이 낮아도 만족, 재구매의도, 긍정적 구전정도가 크게 감소하였다. 둘째, 본 연구는 서비스실패 후 적절한 복구노력을 경험한 고객의 만족이 서비스 실패를 겪기 전보다 높아질 수 있다는 서비스 리커버리 패러독스를 검증하였다. 실험결과 서비스 리커버리 패러독스는 서비스 복구노력수준과 고객-종업원의 친밀도에 관계없이 모든 집단에서 지지되지 않았다. 두 가설의 결과를 종합하여 보면 고객과 종업원의 긍정적인 친밀감은 서비스 실패로 인한 부정적인 영향을 서비스 실패가 없었던 상황으로 되돌릴 수는 없지만, 실패로 인한 부정적인 영향을 감소시켜주는 완충작용을 하는 것으로 나타났다.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제17권3호
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• pp.211-229
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• 2010

Various types of predator-prey systems are studied in terms of the stabilities of their steady-states. Necessary conditions for the existences of non-negative constant steady-states for those systems are obtained. The linearized stabilities of the non-negative constant steady-states for the predator-prey system with monotone response functions are analyzed. The predator-prey system with non-monotone response functions are also investigated for the linearized stabilities of the positive constant steady-states.

• 대한안전경영과학회지
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• 제10권2호
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• pp.25-31
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• 2008

The purpose of this paper is to review the relationship between job characteristics and job stress responses(physiological response, psychological response, behavioral response), and the moderating effect of social support. Based on the responses from 187 employees in small & medium manufacturing industry, hierarchical regressional analysis showed that job characteristics factors have partly negative relationships with job stress response. However, job variety has positive relationship. Social support has partly moderating effect on the relationship between job characteristics and job stress.

• Communications for Statistical Applications and Methods
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• 제24권2호
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• pp.163-172
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• 2017

Economic sentiment is typically measured using ordinary response options. The University of Michigan and the United States Conference Board are two widely used major indexes that have separately established independent consumer sentiment indexes based on three-level ordinary response options: positive, neutral, and negative. Notwithstanding, limited attention has been paid to the structural differences in their built-in formulas, which are referred to the disparate micro scoring schemes applied to an individual question. This paper examines the structural difference of the two indexes and then addresses situations where one is more reliable than the other. Real data from business tendency surveys of the Organization for Economic Cooperation and Development are used to illustrate our points empirically. As a conclusion, it is stressed that the two indexes should be handled with care when applied to economic sentiment comparison studies.

• 한국주거학회논문집
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• 제7권1호
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• pp.105-116
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• 1996

The purpose of this study is to improve the quality of the light environment of classroom. To attain this purpose, this study estimated the physical factor and evaluation of the subjective response of classroon located in south and north in the summer and the winter. The results are as followed. 1. The evaluation of the illumination, uniformity factor, daylight factor as physical factor of light environment is good as classroom, but the classroom in south is better that that in north, the light environment in summer is better than winter. 2. The subjective response to light environment of classroom is positive on both seasons at all calssroom. Comparing summer with winter, I found that the difference of subjective response between both classrooms on summer is attentive. 3. The realtion between subjective response and physical factor of light environment in classroom is attentive on the light sense, content sense, uniformity.

• 한국음향학회:학술대회논문집
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• 한국음향학회 1994년도 FIFTH WESTERN PACIFIC REGIONAL ACOUSTICS CONFERENCE SEOUL KOREA
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• pp.686-691
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• 1994

For evaluating the response fluctuation of the actual environmental acoustic system excited by arbitrary random inputs, it is important to predict a whole probability distribution form closely connected with evaluation indexes Lx, Leq and so on. In this paper, a new type evaluation method is proposed by introducing three functional models matched to the prediction of the response probability distribution from a problem-oriented viewpoint. Because of the positive variable of the sound intensity, the response probability density function can be reasonably expressed theoretically by a statistical Laguerre expansion series form. The relationship between input and output is described by the regression relationship between the distribution parameters(containing expansion coefficients of this expression) and the stochastic input. These regression functions are expressed in terms of the orthogonal series expansion and their parameters are determined based on the least-squares error criterion and the measure of statistical independency.