• Title/Summary/Keyword: Position Marker

Search Result 215, Processing Time 0.028 seconds

Association of the Genotypes of Single Nucleotide Polymorphism Marker rs81437607 with Capric Acid Contents in longissimus dorsi Muscle in Pigs (돼지 등심 내 카프르산 함량과 단일염기다형 마커 rs81437607 유전자형의 상관)

  • Kim, Sang-Geum;Park, Hee-Bok;Kang, Yong-Jun;Shin, Hyunsook;Cho, Sang-Rae;Lee, Wang-Shik;Han, Sang-Hyun;Cho, In-Cheol
    • Journal of Embryo Transfer
    • /
    • v.31 no.3
    • /
    • pp.235-242
    • /
    • 2016
  • This study tested the association between genotypes of the single nucleotide polymorphism (SNP) marker, rs81437607 and capric acid (FA_C10_0) compositions in longissimus dorsi muscle in pigs. Eighteen fatty acid (FA) compositions were measured in a total of 974 $F_2$ animals among 1,106 $F_2$ progeny produced between Landrace and Jeju Black Pig (JBP). Among FA compositions tested, we identified a cluster of highly significant SNPs for capric acid compositions on 58 Mb position of Sus scrofa chromosome 12 (SSC12) using genome-wide association study (GWAS) with $F_2$ genotypes from SNP panel analysis. GWAS results showed that the rs81437607 was the highest trait-related SNP marker with capric acid levels. Three genotypes (C/C, C/T and T/T) of rs81437607 marker were found in $F_2$ population by further pyrosequencing. Association analysis results showed the significant differences between rs81437607 genotypes and capric acid compositions (P<0.05). The $F_2$ pigs harboring rs81437607 C/C ($0.119{\pm}0.002%$) and C/T ($0.116{\pm}0.002%$) genotypes showed additively higher levels of capric acid content than those of T/T homozygotes ($0.109{\pm}0.002%$) ($P=1.30{\times}10^{-12}$). These results suggested that the genetic variations of rs81437607 may be helpful to find causative variants and assist as molecular genetic markers for improving the capric acid contents in longissimus dorsi muscle in pigs.

Identification of Novel Mutations In Adenosine Deaminase Gene In Korean Leukemia Patients (한국인 백혈병 환자에서 아데노신 디아미나제 유전자의 새로운 변이의 확인)

  • Park, Ki-Ho
    • Journal of Life Science
    • /
    • v.20 no.3
    • /
    • pp.453-456
    • /
    • 2010
  • Leukemia is the abnormal increase of hematopoietic progenitor cells in tissues, resulting in anemia, increased susceptibility to infection and impaired blood clotting. The adenosine deaminase (ADA) gene is an important druggable target for the treatment of leukemia patients. Genetic and molecular analyses were performed to determine the effects of ADA gene mutations in 20 leukemia patients in the Korean population. To analyze the relationship between genotype and phenotype, the ADA genomic DNAs - including 1,092 bp of 12 exons and partial intron sequences flanking each exon - were sequenced and compared. In this study, the known mutations in other diseases, more than 50 mutations already reported in patients with severe combined immunodeficiency disease (SCID) and autism, were not found, but two novel mutations in leukemia patients were discovered. They include one nonsense mutation (A>C at nt position 478, F101F) and one missense mutation (G>A at nt position 778, E260K). One missense mutation (G>A at nt position 22, D8Y) was also detected in 20 normal control patients (allelic frequency of 7.5%). Interestingly, subjects in the Korean population retained 2 bp insertion at the intron 6 (IVS6-52insGC), something that has never been shown in other populations. The genetic study to find out the correlation between the mutant alleles and leukemia patients revealed no association statistically (p>0.05). The mutation found in leukemia needs further study to determine its possibility as a molecular marker for the diagnosis of leukemia.

Korean Names

  • Kim, Chin-W.
    • Lingua Humanitatis
    • /
    • v.7
    • /
    • pp.11-30
    • /
    • 2005
  • Historical origins of both personal names and place names in Korea are reviewed. It is shown that names of native origin have been largely replaced by those of Sino-Korean names. Some statistics are given on the basis of the 2000 census data in South Korea. A unique method of naming personal names which contain a generation marker called hangnyol is reviewed. This enables the person to figure out one's position and others in the family tree up to as many as ten generations without going consulting the book of genealogy. While this practice had a role to play in a vertically structured society where seniority is important, it is less practiced as the society is becoming more egalitarian, so that native names, not writable in Chinese characters, are on the rise. In this global age, a person is not just a member of his family or clan, s/he is also a member of the international community. The author proposes several things that should be considered in naming to fit the modern global age: euphony of names, ambiguity, possible bad connotations when Romanized, unintended homophones with comic meanings, etc.

  • PDF

3D Position Information Extraction of Video Image for Motion Simulation (모션 시뮬레이션을 위한 동영상에서의 3D 위치 정보 추출)

  • 박혜선;강신국;박민호;김항준
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2003.04c
    • /
    • pp.223-225
    • /
    • 2003
  • 패턴을 기반으로 딴 AR(Augmented Reality) 시스템은 실시간 동영상 안에 가상 물체들을 정확하게 올리기(registering) 위한 좋은 방법이다. AR 시스템을 구현하기 위해서는 우선 카메라가 보고 있는 영상의 3D 위치 정보를 추출하여야 한다. 본 논문에서는 카메라가 보고 있는 체스판 영상의 3D 위치 정보를 자동적으로 추출하여 그것과 동기적으로 움직이는 가상의 object를 구현하는 시스템을 제안한다. 제안된 방법은 카메라 1 대를 가지고 어떠한 sensor 나 marker 를 사용하지 않고 시간적 정보만을 이용하여 비교적 정확한 3D 위지 정보를 추출할 수 있고, 추출된 3D 위치 정보를 통해 자연스러운 3D 모션 시뮬레이션을 구현할 수 있다.

  • PDF

Camera Calibration and Pose Estimation for Tasks of a Mobile Manipulator (모바일 머니퓰레이터의 작업을 위한 카메라 보정 및 포즈 추정)

  • Choi, Ji-Hoon;Kim, Hae-Chang;Song, Jae-Bok
    • The Journal of Korea Robotics Society
    • /
    • v.15 no.4
    • /
    • pp.350-356
    • /
    • 2020
  • Workers have been replaced by mobile manipulators for factory automation in recent years. One of the typical tasks for automation is that a mobile manipulator moves to a target location and picks and places an object on the worktable. However, due to the pose estimation error of the mobile platform, the robot cannot reach the exact target position, which prevents the manipulator from being able to accurately pick and place the object on the worktable. In this study, we developed an automatic alignment system using a low-cost camera mounted on the end-effector of a collaborative robot. Camera calibration and pose estimation methods were also proposed for the automatic alignment system. This algorithm uses a markerboard composed of markers to calibrate the camera and then precisely estimate the camera pose. Experimental results demonstrate that the mobile manipulator can perform successful pick and place tasks on various conditions.

Estimation of Vehicle Position Based on Magnet Marker Sensing System (도로상 자기표지의 인식을 통한 주행차량 위치 추정)

  • Yun, Kyoung-Han;Byun, Yun-Seob;Min, Kyung-Deuk;Kim, Young-Chol
    • Proceedings of the IEEK Conference
    • /
    • 2009.05a
    • /
    • pp.308-309
    • /
    • 2009
  • 본 논문은 도로상에 매설된 자기표지의 인식을 통해 주행 중인 바이모달 트램의 위치를 추정하는 추정알고리즘 설계 및 검증에 대한 내용을 다룬다. 바이모달 트램은 자동 안내제어를 위해 도로상에 4m 간격으로 매설된 자기표지를 인식하여 차량과 기준경로사이의 경로오차를 측정하고, 이 때 측정된 정보를 이용하여 차량의 위치를 계산한다. 경로오차 측정 정보는 125msec간격으로 이산적으로 주어지며, 차량의 선형모델에 근거한 관측기를 이용하여 차량의 위치를 실시간으로 추정하는 알고리즘을 설계하고, 시뮬레이션을 통해 검증한다.

  • PDF

Development of a Measurement System for High-Speed Spindle Displacement (고속 스핀들의 변위측정 시스템 개발)

  • Kim, H.G.;Chung, W.J.;Ju, J.H.;Cho, Y.D.
    • Transactions of the Korean Society of Machine Tool Engineers
    • /
    • v.17 no.6
    • /
    • pp.8-13
    • /
    • 2008
  • At present many research projects on high-speed spindles are being conducted. These projects require a measurement technique which includes heat expansion, vibration and displacement measurement according to angular velocity. This paper presents the development of a measurement system for high-speed spindle displacement. The measurement system is based on $LabView^{(R)}$ and features the following sensors: optical sensor which reacts to the position of a marker on the spindle and enables two Laser Displacement Sensors(LDS). These Laser Displacement Sensors send their data to a DAQ(Data Acquisition Device). It is important that the delay time caused by the response times of the sensors as well as the sampling rate of the DAQ is considered because the spindle revolves at very high speeds.

A Study on On-board ATO/TWC Antenna Design and Manufacture (차상 ATO/TWC 안테나 설계 및 제작에 관한 연구)

  • Yoo Sung-Ho;Park chong chon;Kang Lee-Taeg;Cho Young-Wan;Cha Ji-Ju
    • Proceedings of the KSR Conference
    • /
    • 2005.05a
    • /
    • pp.903-908
    • /
    • 2005
  • Existing ATC/ATO/TWC system has a ATC(Automatic Train Control) antenna for receiving the speed code, a ATO(Automatic Train Operation) antenna for obtaining the exact distance to go to platform and TWC(Train and Wayside Communication) antenna for communication between on-board and wayside system. This paper proposes the ATO/TWC antenna with tele-powering module, telegram transmitter/receiver module. This antenna communicates with a passive type tag(wayside Precision Stop Marker) for the information of distance from the stop position and a active type tag for the door command and status in the platform.

  • PDF

Matrix Attachment Regions (MARs) as a Transformation Booster in Recalcitrant Plant Species

  • Han, Kyung-Hwan
    • Korean Journal of Plant Tissue Culture
    • /
    • v.24 no.4
    • /
    • pp.225-231
    • /
    • 1997
  • For genetic engineering to be commercially viable, an efficient transformation system is needed to produce transgenic plane from diverse genotypes ("generalized protocol"). Development of such a system requires optimization of a number of components such as gene transfer agent, plant tissues competent for both regeneration and transformation, and control of transgene expression. Although several novel gene transfer methods have been developed for plane, a majority of stably transformed plane express the introduced genes at low levels. Moreover, silencing of selectable marker genes shortly after their incorporation into plant chromosomes may result in low recovery of transgenic tissues from selection. Matrix attachment regions (MARs) are DNA sequences that bind to the cell's proteinaceous nuclear matrix to form DNA loop domains. MARs have been shown to increase transgene expression in tobacco cells, and reduce position in mature transgenic plants. Flanking an antibiotic resistance transgene with MARs should therefore lead to improved rates of transformation in a diversity of species, and may permit recalcitrant species and genotypes to be successfully transformed. Literature review and recent data from my laboratory suggest that MARs can serve as a transformation booster in recalcitrant plant species.

  • PDF

On the Voiced-Voiceless Distinction in Stops of English

  • Kim, Dae-Won
    • Korean Journal of English Language and Linguistics
    • /
    • v.2 no.1
    • /
    • pp.23-30
    • /
    • 2002
  • Phonologically, the difference between the English stops /b, d, g/ and /p, t, k/ is carried by the presence or the absence of the vocal fold vibration throughout their oral closure phase. If phonology has its foundation in phonetics, there must be phonetic evidence for the voiced-voiceless distinction. This study is aimed to determine whether or not the voiced-voiceless distinction is acceptable or proper in English. The determination was based mainly on findings in the existing literature and in informal experiments. In conclusion, there is no phonetic evidence for the voiced-voiceless distinction both in production and perception. The [voice] appears to be one of potential phonetic correlates of the phonologically voiced stop. It is improper to use the [voice] as independent phonological marker, regardless of position (word-initial, intervocalic, word-final). A feature other than the voiced-voiceless feature must distinguish /b, d, g/ from /p, t, k/.

  • PDF