• 제목/요약/키워드: Polythylene

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Micelle, Liposome, Polythylene Glycol을 이용한 Amphotericin B의 세포막 독성저하 (Reduction of Cell Membrane Toxicity of Amphotericin B Using Micelle,Liposome and Polyethyene Glycol)

  • 박인철;이판종;양지원;김종득;최태부
    • 한국미생물·생명공학회지
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    • 제22권3호
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    • pp.290-295
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    • 1994
  • Micelle, liposome and polyethylene glycol(PEG) were employed to reduce the cell mem- brane toxicity of Amphotericin B(Amp. B). Cholesterol-sulfate which can form a mixed micelle with Amp. B molecules was found very effective for the reduction of Amp. B toxicity. 0.01% of cholesterol-sulfate could reduce the toxicity of 5X 10$^{-6}$ M Amp. B by 90%. The required concent- ration of cholesterol-sulfate for the toxicity reduction was proportionally increased with increasing Amp. B concentration. PEG was also effective on the reduction of Amp. B toxicity. 2% PEG was required for the reduction of toxicity by 50%, regardless of Amp. B concentration. The liposome system showed an effective reduction of Amp. B toxicity on RBC, maintaining the antibiotic effect on Candida albicans as free drugs. This seems to be due to the fact that liposome bilayer plays a role of buffer system between ergosterol of fungi cell membrane and cholesterol of red blood cell membrane, which leads the redistribution of Amp. B between them, as the result, the reduction of drug toxicity on cell membrane.

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수용성 블록공중합물에서 산화티탄 분말의 흡착 안정화 (Adsorption Stabilization of $TiC_{2}$ Particles in Water Soluble Block Copolymers)

  • 권순일;정환경;최성옥;남기대
    • 한국응용과학기술학회지
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    • 제18권2호
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    • pp.118-126
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    • 2001
  • Micelle formation and adsorption at the $Ti0_{2}$ interface of a series of polystyrene-polythylene oxide(PS-PEO) block copolymer in aqueous solution was studied using fluorescence probing and small-angle X-ray methods. Further, the stability of aqueous $Ti0_{2}$ dispersion in the presence of copolymer was investigated by microelectrophoresis, optical density and sedimentation measurements. The dissolution of pyrene as fluorescent probe in aqueous surfactant solution leads to a slow decrease of the $I_{1}/I_{3}$ ratio, as the copolymer concentration increase; $I_{1}$ and $I_{3}$ are respectively the intensities of the first and third vibrionic peaks in the pyrene fluorescence emission. The behaviour was due to the characteristics of the copolymers and/or to the copolymer association efficiency in water. Moreover, the adsorption at the plateau level increases with decreasing PEO until chain length. The zeta potential of $TiO_{2}$ particles decreases with increasing copolymer concentration and reaches a plateau value. Finally, stabilization using block copolymers was more effective with samples having higher weight fractions of PS block.

활성화 폴리에틸렌/왁스/아크릴 공중합체의 블렌드에 의한 내구유연발수제의 제조에 관한 연구(I) (Preparation of Durable Softening Water Repellents by Blends of Activated Polyethylene/Wax/Acrylic Copolymer(I))

  • 신재현;김성계;박홍수
    • 한국응용과학기술학회지
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    • 제13권1호
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    • pp.41-46
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    • 1996
  • Durable softening water repellents such as PODCWs were prepared by blending cationized compound of poly(octadecyl methacrylate-co-2-diethylaminoethyl methacrylate), of which synthetic methods were reported in the previous paper, activated polythylene, waxes, and emulsifiers. Water repellency of prepared PODCWs was measured by performing water repellent finish to various fabrics, PODCWs showed a good water repellency for P/C blended fabrics and their repelling tendency was in the order of P/C blended fabrics>cotton fabrics>nylon taffeta. The initial water repellencies of PODCW-1 and PODCW-2 were 100 and $100^{-}$ points, respectively, for P/C blended fabrics. And also, PODCW-1 and PODCW-2 were confirmed as durable water repellents with the results of making little difference of water repellency as ${\pm}5$ point after and before washing.

Aggregation Prodesses of Hydrophobically Modified Polythylene Oxide

  • 백기욱;김범성;김응렬;손대원
    • Bulletin of the Korean Chemical Society
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    • 제21권6호
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    • pp.623-627
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    • 2000
  • Aggregation of hydrophobically end-capped poly(ethylene oxide)s: HEURs, denoted as $C_8$$EO_{380}$$C_8$, $C_12$$CO_{600}$$C_{12}$, and $C_{18}$$EO_{860}$$C_{18}$,are described using static fluorescence, dynamic light scattering, and atomic force microscope (AFM) techniques. The CAC (critical aggregation concentration) was determined by com-paring two fluorescent peaks which were influenced by the polarity of the probe dye molecules, pyrene. The aggregation occurs in concentrations higher than 10 g/L of $C_8$$EO_{380}$$C_8$ and the CAC decreases by increasing the side chain length. The dynamic light scattering experiment shows fast mode and slow mode decays, and both are diffusive. The fast mode does not depend on the concentration, but the slow mode shows concentration dependence influenced by the formation of an aggregated structure. The hydrophobic end groups effect more dominantly than the main chains for the formation of HEUR micelles. By increasing the concentration, the HEUR micelles change their structure from spheres to rodlike micelles, and finally make fused structures, which were visualized with atomic force microscopy.

고려인삼의 근아휴면타파와 생육에 대한 Gibbrerllin과 Kinetin의 효과 (Effect of Gibberellin and Kinetin on Bud Dormancy Breaking and Growth of Korean Ginseng Root (Panax ginseng C.A. MEY.))

  • 박훈;김갑식;배효원
    • Journal of Ginseng Research
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    • 제3권2호
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    • pp.105-112
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    • 1979
  • Effect of gibberllin on the breaking of bud dormancy of root and growth of aerial parts were investigated under laboratory and field condition for the prolongation of shoot growth duration, shortening of fruit bearing age and the increase of root yield. Drop application of GA (0.5ml of 50ppm) on rhizome of one year old root broke bud dormancy better than by low temperature. Soaking for one hour of one year old roots which wintered in the field in GA (50-200ppm) greatly accelerated the emergence of new buds while kinetin was only effective at low level (50ppm). GA substantially increased stem length in early stage and petiole length later on while kinetin increased stem diameter. Under the field condition with polythylene film tunnel (PET) in early spring the soaking in GA (50ppm for 1 hour) of rhizome of 4 year old root with replanting and dropping GA (50ppm, 1ml) on rhizome without replanting brought earlier emergence (29days) in comparison with that in the usual field. PET alone caused 14 day-early emergence. GA increased the length of stem and petiole only in early stage and replanting decreased only petiole length in later stage. Soaking in GA with replanting caused the Pronounced decrease in peduncle length, percentage of (ruin set and dry weight of reproductive organ (fruits and peduncle). Dropping without replanting showed significant decrease only in dry weight of reproductive organ. Fruit maturing was 20 days earlier than in usual held with little difference between GA and PET. It is well expected that GA could be used for early emergence of bud, shortening of root dormancy period, thinning of fruit and higher root yield according to application amount and methods.

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저온저장시 포장방법에 따른 단감의 품질변화 (Changes in the Quality of Sweet Persimmon Fruits with Packaging Methods during Low Temperature Storage)

  • 신승렬;이주백;윤광섭;최종욱;김광수
    • 한국식품저장유통학회지
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    • 제8권3호
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    • pp.252-257
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    • 2001
  • 본 연구에서는 단감의 저장성을 향상시키고자 polythylene 필름 포장방법에 따른 단감의 물성 및 품질의 변화를 조사하였다. 저장방법에 따른 단감의 품질 변화는 농가에서 사용하는 5개씩 포장하여 저온저장시에는 저장 120일가지 저장성을 유지하였고, 1개씩 포장한 경우에는 저장 150일가지 저장이 가능하였고, 품질면에서 아주 우수한 것으로 판정되었다. PE 필름 두께에 따른 품질의 변화는 일반 농가에 사용하고 있는 0.06mm PE 필름으로 포장한 것은 저장성이 떨어졌고 0.08과 0.10mm PE 필름으로 포장시에는 0.06mm PE 필름에 비해 저장성이 증가되었고 품질면에서도 우수하였다. 저장중 경도와 색상은 저장일가 증가함에 따라 약간 감소하는 경향이었고, 특히 1개씩 0.08mm PE 필름으로 포장시 저장 180일까지도 경도와 색상이 수확시와 차이가 없었다.

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파충류 혈장알부민 및 혈색소의 면역학적 비교 (Immunological Comparison of Reptilian Plasma Albumins and Hemoglobins)

  • Park, Sang-Yoon;Kim, Sang-Yeop;Yum, Jung-Joo
    • 한국동물학회지
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    • 제20권4호
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    • pp.169-177
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    • 1977
  • 유혈목이(Rhabdophis tigrimus)의 혈장알부민을 polythylene glycol과 ethanol 침전 방법에 의해 정제하였고 혈색소는 agar-gel 전기영동방법에 의해 정제하였다. 이 두 단백질과 유혈목이 혈장을 각각 토끼에 주사하여 항혈청들을 얻었으며 포유류 1종, 조류 1종, 파충류 9종, 및 양서류 1종의 혈장 및 혈구파쇄물과 면역확산 및 면역 전기영동을 실시하였다. 혈장알부민과 혈장에 대한 항혈청들은 유혈목이 혈장알부민과만 반응을 나타냈고 다른종의 혈장알부민과는 반응을 나타내지 않았다. 혈색소에 대한 항혈청은 8종의 사류 혈색소와 강한 반응을 나타냈다. 파충류의 혈장알부민의 구조는 상당히 빠르게 변형되어져 왔고 파충류의 경우 혈색소 분자는 강한 구조상의 상동성을 갖고 있는 것 같다. 그러므로 파충류의 경우 혈색소 분자의 구조는 혈장알부민의 구조보다 느리게 변형되어져 온 것으로 생각된다.

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용액 및 용융 가공방법에 따른 PE 및 PE 공중합물의 PTC 서미스터 특성 연구 (A Study on the PTC Thermistor Characteristics of Polyethylene and Polyethylene Copolymer Composite Systems in Melt and Solution Manufacturing Method)

  • 김재철;박기헌;남재도
    • 폴리머
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    • 제26권6호
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    • pp.812-820
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    • 2002
  • 본 연구에서는 나노입자인 카본블랙을 고분자에 분산시킨 복합체를 각각 용액혼합과 용융혼합을 이용하여 positive temperature coefficient (PTC) 특성을 연구하였다. 전도성 나노입자인 카본블랙과 고분자 복합체의 저항 통전 (threshold)은 용융혼합하였을 때 카본블랙의 함량이 35wt% 이상에서 나타났으며. 용액혼합에서는 카본블랙 함량이 40 wt% 이상에서 나타났다. Ethyl-one vinylacetate copolymer (EVA)의 경우, 온도의 변화에 따라서 저항이 서서히 증가하다가 용융점 근처에서 극대값을 나타내었지만, high density polyethylene (HDPE)의 경우는 저항이 온도의 변화에 따라 일정하다가 용융점 근처에서 증가하기 시작하여 용융점에서 극대값을 나타내었다. 통전 후의 낮은 저항과, scanning electron microscopy (SEM)으로 관찰한 결과로부터 전도성 나노입자의 카본블랙 분산방법에서 용액혼합의 분산 정도가 용융혼합 못지않게 나타났다. PTC 소재에 전류인가시 큐리온도에서 1차적으로 저항이 증가하였으며, 고분자의 용융점에서 2차적으로 트립온도가 될 때까지 저항이 증가하다가 트립온도 이후에는 저항이 일정하게 유지됨을 알 수 있었다.

광량 및 광질이 고려인삼의 생육과 품질에 미치는 영향 III. 광량이 인삼품질에 미치는 영향 (Effect of Light Intensity and Quality on the Growth and Quality of Korean Ginseng (Panax ginseng C.A. Meyer) III. Effects of Light Intensity on the Quality of Ginseng Plant)

  • 천성기;목성균;이성식
    • Journal of Ginseng Research
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    • 제15권2호
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    • pp.144-151
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    • 1991
  • This study was conducted to elucidate the effects of light intensity using polyethylene (p.E) net shading on the specific gravity, red ginseng quality, sugar and saponin contents of ginseng root. The specific gravity significantly increased in the ginseng roots grown under the P.E net shading as compared with that of common straw shading. The red ginseng quality under the P.E net shading was improved in order of 10, 5, 15, 20, 30% of light intensity and the inside cavity and inside white part decreased remarkably as compared with those of common straw shading. The ginseng roots grown under the P.E net shading at 10% and 15% light intensity showed a significant increase in the total sugar content but a significant decrease in the reducing sugar content at 15% light intensity as compared with those of common straw shading. The amount of total saponin of ginseng roots was increased under the P.E net shading at high light intensity as compared with that of common straw shading and the ginseng roots grown under the P.E net shading at 10% light intensity showed an increase in the diol group saponin but the ratio of PT/PD was decreased. Extract contents of ginseng root under the P.E net shading was higher than those of common straw shading and the roots grown under the P.E net shading at 15% and 20% light intensity resulted in a remarkable increase in extract contents.

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기체충진 포장조건에 따른 신선편이 캠벨 포도의 저장 중 품질변화 (Storage Quality of Ready-to-Eat Campbell Table Grapes as Affected by Active Modified Atmosphere Packaging)

  • 이현희;홍석인;김동만
    • 한국식품과학회지
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    • 제44권5호
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    • pp.559-567
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    • 2012
  • 신선편이 포도 상품의 유통, 판매 중 부패억제 및 품질유지를 위한 환경기체조절포장기법의 활용 가능성을 확인하고자 살균소독, 세척, 절단 과정을 거친 캠벨 포도 시료에 대해 다양한 기체 충진 조건을 적용하여 플라스틱 포장용기에 밀봉한 후 $5^{\circ}C$에 저장하면서 품질변화를 살펴보았다. 고이산화탄소 조건에서 포도의 호흡률은 일반 대기조성에서의 호흡률과 크게 다르지 않았으나, 고산소 조건에서는 산소 소모율이 2배 정도 증가하는 비정상적인 호기호흡이 일어났다. 저온저장 중 포장 내부의 기체조성은 초기 기체충진 조건에 관계없이 $O_2$가 모두 소비되고 고농도의 $CO_2$가 축적되었으나, PE 포장구에서는 약 13% 이상의 $O_2$가 유지되었다. 포도의 품질인자 가운데 생체중량은 대조구인 통기 포장구에서만 1.0% 이상 감소하였고 고산소 처리구에서 가장 낮은 중량감소를 나타내었으며, 과육의 pH, 산도, 가용성 고형분 함량 및 경도, 과피 표면색, 폴리페놀 함량, PPO 활성에서는 기체충진 조건에 의한 유의적 차이를 구분할 수 없었다. 한편 고이산화탄소 처리구에서는 약 $10^1-10^2$ CFU/g 수준의 가장 낮은 미생물 균수를 나타내었으나 저장말기에 이취가 강하게 발생하였고, 고산소 처리구에서는 상대적으로 이취가 적고, 고유의 포도향이 유지되면서 관능검사 평가점수가 다소 높게 나타났다. 결론적으로 적정 농도의 고이산화탄소와 고산소를 병용한 환경기체조절포장은 신선편이 포도의 저장유통 중 품질유지에 효과적임을 확인할 수 있었지만, 최적의 포장조건을 찾기 위해서는 향후 추가적인 연구가 필요하다고 판단된다.