• Sleep Medicine and Psychophysiology
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• v.3 no.1
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• pp.85-95
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• 1996

Obstructive sleep apnea syndrome(OSAS) in childhood is unique and different n-om that in adulthood in several aspects, including pathophysiology, clinical features, diagnostic criteria, complications, management, and prognosis. Characteristic features of childhood OSAS in comparison with the adult form are the variety of severe complications such as developmental delay, more prominent behavioral and cognitive impairments, vivid cardiovascular symptoms, and increased death risk, warranting a special attention to the possible diagnosis of OSAS in children who snore. However, the childhood OSAS is often neglected and unrecognized. We, therefore, report a case of very severe OSAS in a 5-year-old boy who was sucessfully treated with continuous positive airway pressure(CPAP) treatment. Interestingly, the patient was comor-bid with the attention deficit hyperactivity disorder. Prior to the initial visit to us, adenotonsillectomy had been done at the age of 4 with no significant improvement of apneic symptoms and heavy snoring. On the initial diagnostic procedures, marked degree of snoring was audible even in the daytime wake state and the patient was observed to be very hyperactive. Increased pulmonary vascularity with borderline cardiomegaly was noted on chest X-ray. The baseline polysomnography revealed that the patient was very sleep-apneic and snored very heavily, with the respiratory disturbance index(RDI) of 46.9 per hour of sleep, the mean SaO2 of 78.8%, and the lowest SaO2 of 40.0%(the lowest detectable oxygen level by the applied oxymeter). The second night polysomnography was done for CPAP titration and the optimal pressure turned out to be $8.0\;cmH_2O$. The applied CPAP treatment was well tolerated by the patient and was found to be very effective in alleviating heavy snoring and severe repetitive sleep apneas. After 18 months of the CPAP treatment, the patient was followed up with nocturnal polysomnography(baseline and CPAP nights) and clinical examination. Sleep apneas were still present without CPAP on the baseline night. However, the severity of OSAS was significantly decreased(RDI of 15.7, mean SaO2 of 96.2%, and the lowest SaO2 of 83.0%), compared to the initial polysomnographic findings before initiation of long-term CPAP treatment. Wechsler intelligence tests done before and after the CPAP treatment were compared with each other and surprising improvement of intelligence(total 9 points, performance 16 points) was noted. Clinically he was found to be markedly improved in his attention deficit hyperactive behavior after CPAP treatment, but with minimal change of TOVA(test of variables of attention) scores except conversion of reaction time score into normal range. On the chest X-ray taken after 18 months of CPAP application, the initial cardiopulmonary abnormalities were not found at all. We found that the CPAP treatment in a young child is very effective, safe, and well-tolerated and also improves the co-morbid attention deficit hyperactive symptoms. Overall, the growth and development of the child has been facilitated with the long-term use of CPAP. Cardiovascular complications induced by OSAS have been also normalized with CPAP treatment. We suggest that early diagnosis and active treatment intervention of OSAS in children are crucial in preventing and ameliorating possible serious complications caused by repetitive sleep apneas and consequent hypoxic damage during sleep.

• Proceedings of the ESK Conference
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• 1998.04a
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• pp.131-136
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• 1998

2개의 simulated된 잠수 실험 즉, 심도 19 ATA와 24 ATA의 고압 Heliox 환경하에서, 4명의 다이 버를 대상으로 하여연 188일간 매일 23:00부터 익일7:00시 사이에 각 다이버에대해서 표준적인 polysomnography를 기록했다. 2개의 잠수조건 하에서 양 실험 모두 해저에서 체재하는 동안 의 밤과 감압하는 동안의 밤 동안에는 총수면시간 (Total Sleep Time)의 단축, 수면효율(Sleep Efficiency)의 감소, 입면잠시(Sleep Latency)의 연장, 중도각성회수 (Number of Awakeningss) 와 감소를 보였지만, 어느쪽도 뚜려한 변화가 있었다라고는 할 수 없었다. 24 ATA 잠수조건에서 의 해저에서 체재하는 동안의 밤과 감압하는 동안의 밤 동안에서는 19 ATA 잠수조건에 비해서 4 단계수면(stage 4 sleep )만 유의한 감소를 보였다. 2개의잠수조건 모두 잠수기간 중에 있어서 는 각성하기 쉬운 상황이었으며, 기본적인 수면패턴에 있어서는 큰 변화는 보이지 않았다.

• Proceedings of the IEEK Conference
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• 2003.07c
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• pp.2879-2882
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• 2003

Obstructive Sleep Apnea(OSA) is a representative symptom of sleep disorder which is caused by airway obstruction. OSA is usually diagnosed through the laboratory based Polysomnography(PSG) which is uncomfortable and expensive. In this paper, the detection method for OSA events, using ECG, has been developed. The proposed method uses the ECG data sets provided from Physionet. The features for OSA events detection are the average and standard deviation of 1 minute R-R interval, power spectrum of R-R interval and S-pulse amplitude from data sets. These features are applied to the input of Neural Network. To evaluate the method, we used the another ECG data sets. And we achieved sensitivity of 89.66％, specificity of 95.25％. So, we can know that the features proposed in this paper are important to detect OSA.

• Sleep Medicine and Psychophysiology
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• v.26 no.2
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• pp.75-85
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• 2019

A lucid dream is defined as a dream during which a dreamer is aware that she/he is dreaming. The existence of lucid dream has long been known in the literature, but it hasn't been long before it has received attention in sleep medicine. Although many studies have been conducted since validation of the lucid dream in polysomnography by Steven LaBerge in the 1980s, the neuroscience of lucid dreams is still not fully understood. Here the neuroscientific literature on lucid dreaming, including electroencephalographic, neuroimaging, pharmacological and brain stimulation studies, are reviewed. Also this review gives an overview on how lucid dreams are used in clinical and nonclinical areas, ranging from nightmare therapy to research on consciousness and creative problem solving.

• Sleep Medicine and Psychophysiology
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• v.16 no.1
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• pp.16-21
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• 2009

In accordance with the development of EEG and polysomnography in the field of sleep research, the sleep onset period (SOP) between wakefulness and sleep has been considered an important part for understanding the physiology of sleep. SOP in the transition from wakefulness to sleep is a gradual process integrating various viewpoints such as behavior, EEG, physiology and subjective report. Particularly, based on understanding of EEG changes during sleep, SOP has been regarded as a pattern of topographical change in specific frequency and specific state in EEG. Studies on quantitative EEG (qEEG) and event-related potential (ERP) have suggested that SOP shows the changes of functional coordination at the specific cortical areas in qEEG and the changes of regular patterns in response to environmental stimulation in ERP. The development of sleep EEG and topographic mapping of EEG is expected to integrate various viewpoints of SOP and clarify the neurophysiologic mechanism of SOP further.

• Proceedings of the Korea Contents Association Conference
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• 2015.05a
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• pp.145-146
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• 2015

폐쇄성수면무호흡증(Obstructive sleep apnea syndrome : OSAS)은 신경근육계, 호흡계, 심혈관계의 복합적인 질환으로서 사회적, 생리학적으로 심각한 문제를 발생시킬 수 있는 질병이다. 수술적치료를 결정하기에 앞서 환자의 증상 및 징후, 신체 상태와 습관 등을 정밀검사하고, 기도폐쇄가 일상생활 및 정신건강에 미치는 영향을 고려하여 수술여부를 결정하여야 한다. 폐쇄성수면무호흡증후군의 진단에 유용한 검사인 수면다원검사와 Videofluoroscopy의 검사결과를 바탕으로 수술소견을 비교분석하고자 하였다.

• Sleep Medicine and Psychophysiology
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• v.1 no.1
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• pp.9-19
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• 1994

Disorders of intitating and maintaining sleep(DIMS : insomnia) may be a symptom of some other disease or the basic, root problem in some patients. DIMS is usually treated by private physicians or psychiatrists, initially. Many physicians can do to improve the quality of life of the sleep disordered patients by appropriate evaluation and management For the effective management of DIMS patients, the accurate differential diagnosis is essential. In polysomnographic evaluation for insomnia, the physician should consider the aspects of cost-effectiveness to provide the maximal benefits for the patients. For the purpose of this, evaluation of DIMS complaints outside the sleep disorder clinic, indication for referral to a sleep disorder clinic, the role of polysomnopraphy in evaluating DIMS, and polysomnographic findings of different types of DIMS are discussed, together with possible way to diagnose them.

• Sleep Medicine and Psychophysiology
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• v.1 no.2
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• pp.182-187
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• 1994

The Authors report a case of sleep paralysis patient who is 25-years old man. He complained that he has been experiencing episode "being suffocated" during sleep and could not move by himself while semiconsciousness state. He was a only son of divorced parents and could not attach anybody from yong childhood. His symptoms was began intermittently after his early teens. Medical history and physical examination revealed no significant finding. A nocturnal polysomnogram showed loss of muscle tone during terminal REM period and sudden hyperventilation attack followed by wake-up. Psychosocial stress and insufficient sleep were presumed to be an etiological factors. Imipramine 50mg per day almost completely relieved symptoms.

• Sleep Medicine and Psychophysiology
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• v.1 no.2
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• pp.117-124
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• 1994

Obstructive Sleep Apnea Syndrome(OSAS), that is a complex disease of neuromuscular, respiratory and cardiovascular system, can be cured by various treatment such as weight control, medical and surgical intervention. As most of OSAS may be caused by various anatomical abnormalities, preoperative evaluation for exact anatomical site of obstruction must be needed. And various diagnostic procedures such as fiberoptic nasopharyngoscopy, Mueller test, cinefluoroscopy, cephalometry, computerized tomography, polysomnography would be used for this purpose. Uvulopalotopharyngplasty is currently the most popular method for the patient with OSAS among various surgical maneuvers and is very effective for the relieving the symptoms as like snoring, daytime somnolence, and nocturnal restlessness etc. Although subjective improvement is not compatible with it's objective assessment in postoperative evaluation for it's results, uvulopalatopharyngoplasty could be a recommandable surgical procedure because of it's ample effectiveness in promoting symptom improvement without any risk of serious complications.

• Annals of Clinical Neurophysiology
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• v.19 no.1
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• pp.68-70
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• 2017

Flail arm syndrome (FAS), known as one of the atypical amyotrophic lateral sclerosis (ALS) variants, has a similar clinical course and pathologic findings as ALS. Therefore it is difficult to differentiate between ALS and FAS at a glance. There are few reports involving individual analysis of FAS patients to date. The findings of polysomnography (PSG) in patient with FAS are not well known. We report a male FAS patient with review of literatures and several issues related to the diagnostic process.