• 제목/요약/키워드: Polymer wall

검색결과 254건 처리시간 0.02초

Eudragit $RS^{\circledR}$를 이용한 지속 방출형 아스피린 마이크로캅셀의 제조 및 평가 (Preparation and Evaluation of Sustained Release Aspirin Microcapsules Using Eudragit $RS^{\circledR}$ Polymer)

  • 전인구;신동원
    • 약학회지
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    • 제32권1호
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    • pp.26-39
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    • 1988
  • Eudragit $RS^{\circledR}$ polymer was used as a wall material for the microencapsulation of aspirin by a phase separation method from chloroform-cyclohexane system with 5% polyisobutylene (PIB) in cyclohexane, and microcapsules obtained were evaluated by particle size analysis, scanning electron microscopy (SEM), drug release and drug stability test. With PIB as a coacervation inducing agent, smooth and tight microcapsules with less aggregation were obtained. Below 1 : 0.3 core-wall ratio, it was possible to coat individual particle. Variation of production conditions showed that increasing the proportion of wall material, particle size and wall thickness of microcapsules and the concentration of paraffin wax in cyclohexane as a sealant sustained drug release rates effectively. SEM confirmed that larger microcapsules after drug release did not rupture into smaller particles but contained a few small pores on the surface. Aspirin release from Eudragit $RS^{\circledR}$ coated microcapsules was independent of the pH of medium, and the mechanism of drug release from non-sealed and sealed microcapsules appeared to fit Higuchi matrix model kinetics. Aspirin in the mixture of aspirin microcapsules and sodium bicarbonate was by far more stable than that in the mixture of pure aspirin and sodium bicarbonate.

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Enhancement of Electrocatalytic Activity upon the Addition of Single Wall Carbon Nanotube to the Redox-hydrogel-based Glucose Sensor

  • Kim, Suk-Joon;Quan, Yuzhong;Ha, Eunhyeon;Shin, Woonsup
    • Journal of Electrochemical Science and Technology
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    • 제12권1호
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    • pp.33-37
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    • 2021
  • In electrochemical glucose sensing, the enhancement of the sensitivity and the response time is essential in developing stable and reliable sensors, especially for continuous glucose monitoring. We developed a method to increase the sensitivity and to shorten the response time for the sensing upon the appropriate addition of single wall carbon nanotube onto the osmium polymer-based hydrogel electrode. Also, the background stabilization is dramatically enhanced.

전단박화유체의 수직상향 난류유동시 저항감소에 관한 연구 (A Study on the Drag Reduction of Shear Thinning Fluid with Vertical upward Turbulent Flow)

  • 차경옥;김봉각;김재근
    • 대한기계학회논문집B
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    • 제22권12호
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    • pp.1647-1656
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    • 1998
  • The drag reduction is the phenomenon that occurs only when the shear stress from the wall of pipe is beyond the critical point. The drag reduction increase as the molecular weight, concentration of the polymer and Reynolds number increase, but it is limited by Virk's maximum drag reduction asymptote. Because of the strong shear force for the polymer on the turbulent flow, the molecular weight and the drag reduction do not decrease. Such mechanical degradation of the polymer occurs in all polymer solvent systems. This paper is to identify and develop high performance polymer additives for fluid transportations with the benefits of turbulent drag reduction. In addition, drag reduction in vertical flow by measuring the pressure drop and local void fraction on vertical-up flow of close system is evaluated.

폴리머 수용액 주입에 의한 난류마찰저항 감소에 대한 실험 연구 (Experimental Study on Frictional Drag Reduction of Turbulent Flow by Polymer Solution Injection)

  • 김형태;김덕수;김우전
    • 대한조선학회논문집
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    • 제40권3호
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    • pp.9-15
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    • 2003
  • An experimental study has been carried out as a basic research for development of the friction drag reduction technology for ships by polymer injection. Experimental apparatus and procedures have been devised and prepared to measure the changes of the wall friction with injection of a polymer solution and basic experimental data on the friction drag reduction are obtained for a turbulent fiat-plate boundary layer and fully-developed channel flows. Variations of the friction drag reduction with some important parameters of polymer injection, such as the concentration of polymer solution, its injection flow rate and the measuring position downstream from the injection slot, are also investigated. Important experimental data and results obtained in the present study are presented. The amount of friction drag reduction up to 50% is observed.

FRP로 보강한 비보강 조적 벽체의 전단강도 산정 (Evaluation of Shear Strength of Unreinforced Masonry Walls Retrofitted by Fiber Reinforced Polymer Sheet)

  • 배백일;윤효진;최창식;최현기
    • 콘크리트학회논문집
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    • 제24권3호
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    • pp.305-313
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    • 2012
  • 비보강 조적조 건축물은 전세계적으로 기존의 건물 및 역사 건축물의 많은 부분을 차지하고 있다. 특히, 최근 지진이 전세계적으로 빈번하게 나타남에 따라 비보강 조적조 구조물에 대한 내진 보강 대책이 요구되고 있다. 현재 비보강 조적조의 보강방법으로는 숏크리트, ECC jacketing, FRPs(fiber reinforced polymer sheet) 등이 개발되어 사용되고 있다. 특히 많은 엔지니어들이 FRPs를 사용한 보강방법을 채택하는 경향이 보이는데 이는 숏크리트나 ECC jacketing과는 달리 벽체의 두께 확장에 따른 구조물 자중 증가 문제없이 비보강 조적조의 전단강도를 향상시킬 수 있기 때문이다. 그러나 비보강 조적 벽체의 복잡한 역학적 거동과 FRPs를 사용한 실험 데이터의 부족은 아직까지도 적절한 보강량을 산정하는데 어려움을 주고 있다. 이 연구는 비보강 조적조의 면내 거동을 확인하고 두 가지의 다른 특징을 가진 FRPs를 사용한 보강 효과에 대한 정보를 주기 위해 수행되었다. 실험체는 1970년대 한국에서 빈번하게 지어진 저층형 연립주택의 내벽을 대상으로 하고 있으며 별도의 내진 설계는 되어있지 않은 상태이다. 실험체의 형상비는 실제 상황을 반영하기 위해 1에 가깝게 설정되어 있다. 보강 재료로는 탄소섬유보강 시트와 하이브리드 시트를 사용하였으며 이들은 각각 다른 극한 강도와 탄성계수 및 극한 변형률을 보유하고 있다. 연구 결과 비보강 조적 벽체의 면내 전단력 저항 성능을 확인하였으며 FRPs가 사용된 내진 보강 방안의 특성을 분석할 수 있었다. 또한 FRPs를 사용한 보의 전단보강 방법에 착안하여 비보강 조적조에 대한 FRPs의 보강 설계안을 도출할 수 있었다.

고분자물질(高分子物質) 첨가(添加)에 따른 마찰저항감소(摩擦抵抗減少)에 관한 연구(硏究) (A Study on the Drag Reduction with Polymer Additives)

  • 김재근;차경옥;최형진;김종보
    • 설비공학논문집
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    • 제8권2호
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    • pp.198-207
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    • 1996
  • It is well known that drag reduction in single phase liquid flow is affected by polymer material, molecular weight, polymer concentration, pipe diameter, and flow velocity. Drag reduction in two phase flow can be applied to the transport of crude oil, phase change system such as chemical reactor, pool and boiling flow, and to present cavitation which occurs in pump impellers. But the research of drag reduction in two phase flow is not sufficient. The purpose of the present work is to evaluate the drag reduction by measuring pressure drop, void fraction, mean liquid velocity, and turbulent intensity whether polymer is added in the horizontal two phase system or not. Experiment has been conducted in a test section with the inner diameter of 24mm and the length of 1,500mm. The polymer materials used are two kinds of polyacrylamide[PAAM] and co-polymer[A611P]. The polymer concentration was varied with 50, 100 and 200 ppm under the same experimental conditions. Experimental results showed that the drag reduction of co-polymer is higher than that of polyacrylamide. Mean liquid velocities increased as polymer was added, and turbulent intensity decreased inversely near the pipe wall.

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집.배수용 투수성 폴리머 콘크리트 관의 농업 수리시설물의 현장적용 (Field Application of Permeable Polymer Concrete Pipe for Drainage)

  • 민정기;연규석;성찬용
    • 한국농공학회지
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    • 제45권6호
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    • pp.136-143
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    • 2003
  • This study is performed to evaluate performance of the developed pipe when using for underground drainage in fm land, the efficiency of the pipe is examined such as quantity of drainage, water temperature and other field performance in all weather condition. Results of this study, the higher permeability through wall of the pipe is achieved by making various size pores using open-graded aggregate. And in all weather conditions, permeable polymer concrete pipe perform much better than conventional perforated pipes. During rice farming period, quantity of drainage the permeable polymer concrete pipe is 1.25 time greater than conventional perforated pipes. Therefore, use of the permeable polymer concrete pipe is greater advantages when considering collecting and draining capacity compared with conventional perforated pipes.

고분자용액에 의한 유체수송관벽의 저항감소 -III. 저항감소유체의 입구흐름 영역에 대한 고찰- (Drag Reducton of Pipe Wall For Fluid Flow due to Injected Polymer Solution - III. Consideration of Entrance Region Flow of Drag Reducing Fluids-)

  • 김영보;유경옥
    • 한국화재소방학회논문지
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    • 제5권2호
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    • pp.21-35
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    • 1991
  • As a part of studies of drag reduction phenomenon, at the entrance flow region of abrupt contraction tube flowing water, dilute and concentrated drag reducing polymer solutions contraction losses are estimated experimentally. Futher more, entrance lengths are considered theoretically and are measured experimentally. In the present experiment, fluid temperature is fixed l$0^{\circ}C$ and flow rates are 3,000

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Study of Equivalent Retention among Different Polymer-Solvent Systems is Thermal Field-Flow Fractionation

  • 김원숙;박영훈;문명희;유유경;이대운
    • Bulletin of the Korean Chemical Society
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    • 제19권8호
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    • pp.868-874
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    • 1998
  • An equivalent retention has been experimentally observed in thermal field-flow fractionation (ThFFF) for different polymer-solvent systems. It is shown that iso-retention between two sets of polymer-solvent systems can be obtained by adjusting the temperature difference (ΔT) according to the difference in the ratio of ordinary diffusion coefficient to thermal diffusion coefficient. This method uses a compensation of field strength (ΔT) in ThFFF at a fixed condition of cold wall temperature. It is applied for the calculation of molecular weight of polymers based on a calibration run of different standards obtained at an adjusted AT. The polymer standards used in this study are polystyrene (PS), polymethylmethacrylate (PMMA), and polytetrahydrofuran (PTHF). Three carrier solvents, tetrahydrofuran (THF), methylethylketone (MEK) and ethylacetate (ETAc) were employed. Though the accuracy in the calculation of molecular weight is dependent on the difference in the slope of log λ vs. log M which is related to Mark-Houwink constant a, it shows reasonable agreement within about 6% of relative error in molecular weight calculation for the polymer-solvent systems having similar a value.

급속 금형가열에 의한 박육 사출성형의 유동특성 개선에 관한 연구 (A Study on Improvement of Flow Characteristics for Thin-Wall Injection Molding by Rapid Mold Heating)

  • 박근;김병훈
    • 소성∙가공
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    • 제15권1호
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    • pp.15-20
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    • 2006
  • The rapid thermal response (RTR) molding is a novel process developed to raise the temperature of mold surface rapidly to the polymer melt temperature prior to the injection stage and then cool rapidly to the ejection temperature. The resulting filling process is achieved inside a hot mold cavity by prohibiting formation of frozen layer so as to enable thin wall injection molding without filling difficulty. The present work covers flow simulation of thin wall injection molding using the RTR molding process. In order to take into account the effects of thermal boundary conditions of the RTR mold, coupled analysis with transient heat transfer simulation is suggested and compared with conventional isothermal analysis. The proposed coupled simulation approach based on solid elements provides reliable thin wall flow estimation for both the conventional molding and the RTR molding processes.