• Food Science of Animal Resources
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• v.26 no.3
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• pp.386-393
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• 2006

The effects of Curcuma extract Solomon's seal (Polygonatum odoratum var. pluriflorum), and maltodextrose on acute hepatotoxicity in Sprague-Dawley (SD) rats were investigated. Acute hepatotoxicity was induced by 0.5 mL of carbon tetrachloride ($CCl_4$) per kg of SD rats, which was injected to them before administration of Curcuma extract or both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures. SD rats dose with Curcuma extract of 4 mg or 40 mg per kg per day significantly (p<0.05) reduced the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALKP) after 7 days compared to the controls dose with water. Treatments of Curcuma extract with 4 mg per kg per day in SD rats significantly (p<0.05) reduced aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALKP) to 78.0%, 82.6%, and 76.3% after 7 days compared to the controls, respectively. The levels of AST and ALT in SD rats dose with both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures or either alone had no significantly different (p>0.05) compared to the controls. Treatments of Curcuma extract combined with Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures was 'liked more' to the sensory scores for odor and flayer compared to the controls. It was considered that Curcuma extract combined with both Solomon's seal (Polygonatum odoratum var. pluriflorum) and maltodextrose mixtures could be used to functional food for enhancement of health and consumer acceptance.

• The Korea Journal of Herbology
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• v.29 no.2
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• pp.15-21
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• 2014

Objectives : The purpose of this study was to investigate inhibitory effects of steamed Polygonatum odoratum extract (POE) on differentiation and adipogenesis in 3T3-L1 adipocytes. Methods : Polygonatum odoratum (P. odoratum) extract was extracted with ethyl acetate. Total phenolic and flavonoid contents in POE were measured for antioxidant activity. The spectrophotometric method was used to determine the DPPH and ABTS radical scavenging activity and ferric-reducing antioxidant potential (FRAP). MTT assay was examined for cell toxicity, oil red O staining was performed for intracelluar adipogenesis in differentiated 3T3-L1 adipocytes. Western blot analysis for measurement of CCAAT/enhancer-binding protein ${\alpha}$ ($C/EBP{\alpha}$), peroxisome proliferator-activated receptor${\gamma}$ ($PPAR{\gamma}$) and AMP-activated protein kinase (AMPK) expressions were performed. Results : The results revealed that POE has antioxidant activities. Contents of total polyphenolics and flavonoids were $50.83{\pm}1.52$ GAE mg/100g dry weight of POE and $17.05{\pm}2.47$ RE mg/100g dry weight of POE, respectively. DPPH radical scavenging activity, and FRAP in 10 mg/ml concentration were $92.1{\pm}0.6%$, $244.8{\pm}9.0{\mu}M$ Fe(II) and ABTS inhibition in 5 mg/ml concentration was $84.8{\pm}4.1%$. Treatment of POE in adipocytes inhibited the differentiation and adipogenesis of 3T3-L1 adipocytes compared to those of vehicle control. Additionally, protein expressions of $C/EBP{\alpha}$ and $PPAR{\gamma}$, major transcription factor for the adipogenic genes, were significantly decreased compared to those of vehicle control (p<0.05). Futhermore, phosphorylation of AMPK was increased in 3T3-L1 adipocytes treated with POE compared to that of vehicle control (p<0.05). Conclusions : we demonstrate that steamed P. odoratum extract (POE) has potentiating antioxidant activities, inhibits differentiation and lipid accumulation and also induces energy expenditure in adipocytes, which may contribute to antiobesity property.

• Korean Journal of Medicinal Crop Science
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• v.6 no.2
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• pp.142-148
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• 1998

The Polygonatum spp. used in this study was collected from 1994 to 1997, and planted by species in Hamyang medicinal plant experimental station field. $30{\sim}40 $ species of Polygonatum spp. have been known to be distributed in the northern hemisphere, and $14{\sim}18$ species in Korea. In this study, collected seven species of Polygonatum spp. were investigated. Plant height was highest in Polygonatum stenophyllum followed by P. falcatum, P. humile, P. lasianthum var. coreanum.. Leaf length was longest in P. falcatum and shortest in P. odoratum and leaf width was the most wide in P. odoratum var. pluriflorum. P. stenophyllum had 111 flowers per stem. The other species had $14{\sim}22$ flowers per stem. The ratio of flower setting in each species was high at two but was 95.2% at above four in P. stenophyllum. The number of fruits was 14.8, 15.4 and 17.7 in P. odoratum, P. falcatum and P. humile, respectively. Other species did not produce fruit. Fruit setting percentage was high in P. odoratum as 81.5%. The number of branched rhizome doubled every year.

• Landscaping Tree
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• s.90
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• pp.22-23
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• 2006

• Proceedings of the Korean Nutrition Society Conference
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• 1997.05b
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• pp.48-48
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• 1997

• Food Industry And Nutrition
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• v.6 no.2
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• pp.3-12
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• 2001

• Korean Journal of Medicinal Crop Science
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• v.9 no.3
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• pp.238-242
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• 2001

Growth and rhizome yield of Polygonatum odoratum were studied in different planting distance, ${30{\times}10,\;30{\times}20\;,30{\times}30\;cm}$. Plant height was taller in dense planting, $30{\times}10cm$ than the other planting distance, and was increased as cultivation period extended. Stem number also increased by dense planting. The fresh rhizome weight per plant was 225g at $30{\times}10cm$, 215g at $30{\times}20cm$, 1989 at $30{\times}30cm$. The fresh rhizome yield was highest at dense planting, $30{\times}10cm$. Therefore, optimum planting distance of Polygonatum odoratum was $30{\times}10cm$.

• Food Science and Preservation
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• v.17 no.6
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• pp.835-846
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• 2010

The manufacture of beverages prepared using hot-water extracts of Polygonatum odoratum var. pluriflorum, Houttuynia cordata, and Lycium chinensis was statistically optimized using response surface methodology. The total polyphenol content, electron donation activity, and reducing power of optimized beverages were measured to evaluate antioxidant properties. The coefficients of determination, the $R_2$ values, were 0.9887~0.9957 for color, taste and overall acceptability. Analysis of variance showed that the model fit was a statistically significant (p<0.05). The optimized compositions of processed beverages were: Polygonatum odoratum var. pluriflorum extract, 2.15%; Houttuynia cordata extract, 1.74%; and Lycium chinensis extract, 0.19% (all w/w). Total polyphenol content, electron donation activity, and reducing power of beverages of optimized composition were 3.61 mg/L, 23.78%, and 0.26, respectively.

• Korean Journal of Food Science and Technology
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• v.39 no.1
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• pp.99-103
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• 2007

In order to evaluate innate flavor during the roasting process, the components responsible for the aroma of unroasted Polygonatum odoratum root and the volatile odor components released during the roasting process were evaluated using the solid phase-microextraction (SPME) headspace method. The raw P. odoratum root contained aldehyde, alcohol, hydrocarbon and acid components, which gave it a grass-like smell. 2-Methylpyrazine was not revealed from the roasted P. odoratum root at $110^{\circ}C$ and $130^{\circ}C$, but was extracted at $150^{\circ}C$. The 2,5-dimethylpyrazine component was the greatest at $130^{\circ}C$. The hexanal component was greater when the root was roasted at $110^{\circ}C$, compared with those at $130^{\circ}C$ and $150^{\circ}C$. The production of 2-acetyl-1-pyrroline component was the greatest when it was roasted at $130^{\circ}C$. Quantitative descriptive analysis of P. odoratum after roasting revealed a high concentration of 2,5-dimethylpyrazine at $130^{\circ}C$ and $150^{\circ}C$, but a low concentration at $110^{\circ}C$. Most of the 2-acetyl-1-pyrroline, which significantly affected its smell, was revealed at $130^{\circ}C$.

• Korean Journal of Medicinal Crop Science
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• v.12 no.3
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• pp.214-218
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• 2004

Germplasms having valuable characters are increasjngly important for modern breeding programs. This study was conducted to obtain the basic data for effective use of genetic resources of Polygonatum. The relationship of seven Polygonatum species collected widely in Korea was analyzed by RAPD markers. Total number of alleles amplified by nineteen random primers were 114 to 157, and variation in number of alleles was also diverse among seven species examined. The seven species were divided into two groups; one was of Polygonatum stenophyllum and Polygonatum humile. the other was of Polygonatum inflatum, Polygonatum lasianthum, Polygonatum odoratum var. pluriflorum (1), (2), and for variegatum.