• 제목/요약/키워드: Polyethylene Glycol treatment

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Polyethylene Glycol을 이용한 수침목재의 보존처리

  • 김용한
    • 보존과학연구
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    • 통권5호
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    • pp.179-188
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    • 1984
  • 본문은 Conservation of Water logged Wood(1979, Netherlands National Commission for UNESCO)중의 "The Use of Polyethylene glycol for the Treatment of Waterlogged wood-its Past and Future(Dr.C.Pearson)" 및 "The Conservation of ship wrecks by impregnation with Polyethylene glycol (Dr.J.deJong)"을 역편한 것임.

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소아의 만성 기능성 변비 치료에 polyethylene clycol 4000과 락툴로스의 효과 비교 (Comparison of polyethylene glycol 4000 and lactulose for treatment of chronic functional constipation in children)

  • 엄지현
    • Clinical and Experimental Pediatrics
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    • 제50권8호
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    • pp.752-756
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    • 2007
  • 목 적 : 만성 기능성 변비 환아의 치료에서 PEG 4000과 락툴로스의 임상적 효용성에 대해 비교 분석 하였다. 방 법 : 2004년 9월부터 2007년 2월까지 노원 을지병원 소아과에 만성 반복성 복통이나 배변 장애를 주소로 내원하여 만성 기능성 변비로 치료받고 1년간 외래 추적이 가능했던 환아 56명을 대상으로 하였다. 전해질이 함유되지 않은 PEG 4000을 투여한 24명의 환아와 락툴로스를 투여한 32명의 환아들을 대상으로 치료 시작시와 치료 1개월, 3개월, 6개월, 1년 후에 각 약물의 효과와 부작용에 대해 비교 분석하였다. 결 과 : 두 군 모두 배변 횟수가 치료전에 비해 유의하게 증가하였고(P<0.05), 복통 또한 치료 전에 비해 유의한 감소가 있었다(P<0.05). 치료를 시작한 시점에서 12개월이 되었을 때 변비와 유분증으로부터의 회복은 PEG 투여군에서는 12례(60%)에서, 락툴로스 투여군에서는 15례(57.7%)에서 있었으며 두 군 간에 유의한 차이는 없었다. 결 론 : 유소아 만성 변비에서 PEG 4000과 락툴로스는 장기적 유지 요법으로 안전하고 효과적인 약물이며 변비와 유분증으로부터의 회복에 두 군간에 유의한 차이는 없었다.

Polythylene glycol을 이용한 모의적 토양수분 조절방법이 목초의 발아에 미치는 영향과 유효성 (Effects of Drought by Polythylene glycol Solution on Seven Grasses Germination)

  • 윤세형
    • 한국초지조사료학회지
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    • 제10권2호
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    • pp.70-76
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    • 1990
  • The present study elucidates the effect of drught by polyethylene glycol solution on germination of five temperate and two tropical grasses. The results obtained can be summarized as follows: 1. The germination percentage of seven grasses decreased with increasing concentration of polythylene glycol. 2. The germination pattern hi higher concentration of polyethylene glycol showed similar trends to the emergence pattern under drought stress in soil condition. 3. The treatment of 30g is most useful at this study. Therefore, polythlene glycol was the appropriate to creat the drought condition of soil.

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Polyethylene glycol처리과정 중 목재 치수안정성의 경시적 평가 (Estimation of dimensional stability of woods with time by Polyethylene glycol treatment)

  • 권구중;김남훈
    • 한국가구학회지
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    • 제13권1호
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    • pp.2-8
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    • 2002
  • This study was carried out to investigate the reasonable condition for better dimensional stability in woods by polyethylene glycol(PEG) treatment. Eight species grown in Kangwon-do were used for this study. Three species of softwoods(Pinus densiflora, Pinus koraiensis, Larix kaempferi) and two species of hardwoods(Prunus sargentii, Populus tomentiglandulosa) treated with 30% aqueous solution of PEG 1000 showed good dimensional stability under the treatment for 1 day. The dimensional stability of Betula davurica, Quercus mongolica and Quercus variabilis woods increased with increasing treatment time. From the above results, it was concluded that PEG penetration and dimensional stability were affected by characteristics of wood species such as density and structure.

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Agrobacterium tumefaciens Spheroplast의 연초엽육 Protoplast내 도입에 관한 세포학적 연구 (Cytological Study of the Introduction of Agrobacterium tumefaciens Spheroplasts into Nicotiana tabacum Protoplasts)

  • 김정희;구용범;이기영
    • Journal of Yeungnam Medical Science
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    • 제2권1호
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    • pp.175-181
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    • 1985
  • Polyethylene glycol(PEG) 처리에 의한 Agrobacterium tumefaciens spheroplast와 연초 엽육 protoplast의 상호작용을 연구하기 위하여, 효소적 방법으로 분리한 연초엽육 protoplast와 carbenicillin 및 lysozyme의 처리에 의해 제조된 Agrobacterium tumefaciens ATCC 15955 spheroplast를 섞어서 polyethylene glycol (PEG) 및 high pH-high $Ca^{2+}$ buffer를 처리한 후 시료를 취하여 전자현미경으로 관찰한 결과, spheroplast는 초기 단계에서 protoplast membrane에 부착하고, 시간이 경과함에 따라 endocytosis에 의해 protoplast의 세포질 내부로 도입된 다음, 점차로 그 형체(cell integrity)가 파괴되어지는 것을 관찰할 수 있었다. 이러한 관찰 결과로부터 spheroplast는 polyethylene glycol(PEG)에 의해 protoplast내부로 endocytosis되어짐을 알 수 있었다.

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Anti-tumor Activity of Paclitaxel Prodrug Conjugated with Polyethylene Glycol

  • Lee, Keyong-Ho;Chung, Yong-Jun;Kim, Youn-Chul;Song, Seog-Jeong
    • Bulletin of the Korean Chemical Society
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    • 제26권7호
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    • pp.1079-1082
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    • 2005
  • The purpose of this study was to develop a method for increasing the solubility of paclitaxel in water to reduce its toxicity and make the drug more feasible for chemotherapy. A series of highly water soluble paclitaxel polyethylene glycol (PEG) esters were synthesized and evaluated for their anti-tumor activity and toxicity. The solubility of 7-polyethylene glycol paclitaxel carbonate 5 was 840 mg/mL and the acute toxicity ($LD_{50}$) was 286 mg/kg. Because of its reduced toxicity, compound 5 showed a dramatic reduction of tumor volume without any loss of animals in long-term treatment (daily consecutive injections for 15 days).

PEG(Polyethylene Glycol)처리재의 역학적 특성 (Mechanical properties of domestic small-diameter logs treated with Polyethylene glycol)

  • 권구중;김남훈
    • 한국가구학회지
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    • 제12권2호
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    • pp.19-27
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    • 2001
  • This study was carried out to investigate the mechanical properties of woods treated with 30% aqueous solution of PEG 1000. Compressive, bending and shearing strengths were slightly decreased by PEG treatment. Absorbed energy in impact bending did not show any significant differences between untreated and PEG-treated woods.

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Polyethylene glycol이 3가크롬 전기도금에 미치는 효과 (The Effect of Polyethylene Glycol on the Trivalent Chromium Electroplating)

  • 이주열;;임성환;한승전;권식철
    • 한국표면공학회지
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    • 제44권1호
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    • pp.7-12
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    • 2011
  • The effect of organic additives, polyethylene glycol (PEG), on the trivalent chromium electroplating was analysed in the view point of current efficiency, solution stability and metallurgical structure. It was measured that PEG-containing trivalent chromium solution had about 10% higher current efficiency than pure solution and controlled the micro-crack density of electrodeposits. PEG exhibited profound effect on the solution stability by reducing the consumption rate of formic acid which acts as a complexant to lower the activation energy required for electrochemical reduction of trivalent chromium ions. It was also revealed that the formation of chromium carbide layer was facilitated in the presence of polyethylene glycol, which meant easier electrochemical codeposition of chromium and carbon, not single chromium deposition. Trivalent chromium layer formed from PEG-containing solution was amorphous with local nano-crystalline particles, which were prominently developed on the entire surface after non-oxidative heat treatment.

고분자량 Polyethylene Glycol 처리에 따른 모직물과 유사모직물의 보온성과 태의 향상 방안 모색 (An Approach to Improve Thermal Insulation Properties and Fabric Hand of Wool and Wool-like Fabrics under High Molecular Polyethylene Glycol Treatment)

  • 조길수;이은주
    • 한국의류학회지
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    • 제21권6호
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    • pp.1041-1050
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    • 1997
  • This study was carried out to improve the thermal insulation properties of wool and wool- like fabrics by treating the fabrics with polyethylene glycol, to evaluate the fabric hand of PEG treated wool and wool-like fabrics and to grade up the fabric hand of the treated fabrics by treating with softening agents. Wool and wool-like fabrics were treated with high molecular PEG-8,000 by PDC. The thermal release/storage properties were measured on a DSC. Hand of specimens were evaluated by KES-FB system. The results were as follows; 1. PEG-treated fabrics showed thermal storage and thermal release properties by DSC and the heat contents were generally proportional to the add-ons. 2. PEG-treated fabrics showed higher Koshi and lower Numeri and Sofutosa values due to lower tensile energy and recovery and higher bending rigidity and shear stiffness as the add- ons increased. 3. PEG-treated fabrics showed much lower bending rigidity after softening agents treatment.

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$\alpha$-Amylase 저해제 생성균 Streptomyces actuosus DMCJ-49와 Streptomyces minoensis DMCJ-144의 종간 융합에 의한 균주 개량 (Strain Improvement by Interspecific Fusion of Streptomyces actuosus DMCJ-49 and Streptomyces minoensis DMCJ-144 producing $\alpha$-Amylase Inhibitor)

  • 김지현;최응칠;김병각
    • 약학회지
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    • 제35권1호
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    • pp.30-37
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    • 1991
  • Streptomyces actuosus DMCJ-49 and Streptomyces minoensis DMCJ-144 produce the .alpha.-amylase inhibitor. Inerspecific protoplast fusion technique was used to increase the productivity of .alpha.-amylase inhibitor. Four auxotrophic mutants were obtained respectively from two strains by N-methyl-N'-nitor-N-nitrosoguanidine(3mg/ml) treatment. The optimum conditions for the protoplast formation of Streptomyces actuosus DMCJ-49 ade was as follows; 1.2% w/v of glycine, 3mg/ml of lysozyme, and 30 min of lysozyme treatment followed by 36 hr. incubation in the protop-last formation medium. In case of DMCJ-144-his those were 1.2%w/v, 3 mg/ml, 30 minutes and 60 hours, respectively. Regeneration was accomplished with hypertonic soft agar medium that contained 0.4M sucrose, 20mM CaCl$_2$, 50 mM MgCl$_2$ and low levels of phosphate. Fusion of protoplasts carrying different auxotrophic markers was achieved by treatment with polyethylene glycol. The optimum concentration of polyethylene glycol 1450 for the production of recombinants was 40%w/v. When the protoplasts was treated with 40% polyethylene glycol for 30 minutes, the frequency of recombinants was 6.5$\times$$10^{-3}$ and the $\alpha$-amylase inhibition activity of $ade^-his^-$ No. 4, which is the fusant with the most improved activity increased from 33 to 125 I.U./ml.

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