• Journal of Pharmaceutical Investigation
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• v.39 no.3
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• pp.201-205
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• 2009

Triglyceride solid lipid with medium chain fatty acid, tricaprin (TC), was used as a core matrix of lipid nanoparticles (LN) to solubilize water-insoluble paclitaxel and enhance the stability of nanoparticles by immobilization of incorporated drug in the solid core during storage at low temperature. In the present study, TC-LN containing paclitaxel was prepared by hot melt homogenization method using TC as a core lipid and phospholipids as stabilizers. The particle size of TC-LN containing paclitaxel was less than 200 nm and its zeta potential was around -40 mV. Calorimetric analysis showed TC core could be solidified by freezing and thawing in the manufacturing process in which the hot dispersion should be prepared at elevated temperature and subsequently cooled to obtain solid lipid nanoparticles. The melting transition of TC core was observed at $27.5^{\circ}C$, which was lower than melting point of TC bulk. The particle size of TC-LN remained unchanged when kept at $4^{\circ}C$. Paclitaxel containing TC-LN showed comparable anticancer activity to the Cremophore ELbased paclitaxel formulation against human ovarian (OVCAR-3) and breast (MCF-7) cancer cell lines. Thus, lipid nanoparticles with medium chain solid lipid may have a potential as alternative delivery system for parenteral administration of paclitaxel.

• Journal of the East Asian Society of Dietary Life
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• v.18 no.2
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• pp.264-275
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• 2008

Seven constructs of sanitary management were evaluated in order to examine perceived performance of sanitary management and sanitary recognition for school food service managers in the Kyunggido area. In order to protect from foodborne illness, 331 (58.4%) responded that the most important aspects were sanitary conditions and stability upon food delivery, and the greatest obstacle was limited availability of facilities and equipment (182, 32.2%). The total mean score for the perceived performance of sanitary management was $4.16{\pm}0.445$ (5-point Likert scale). Among three sectors, personal hygiene management was generally well-conducted with a subtotal mean score of $4.52{\pm}0.458$; however temperature management scored lowest with a subtotal mean of $3.71{\pm}0.630$. Chi-square tests were performed according to general characteristics on the two lowest perceived sanitary management performance areas. In temperature management, there was a significant difference in 5 sectors according to age, and the ages $20{\sim}29$ showed the best perceived performance in all sectors. For serving management, a significant difference (p<0.01) was shown in all sectors. In conclusion, foodservice managers perceive that sanitary management is well-executed. However, the combination of proper equipments and facilities would lead to better perceived management.

• Journal of Power Electronics
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• v.17 no.1
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• pp.305-313
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• 2017

A novel interference isolation method is proposed by using several designed coils in capacitive power transfer systems as isolation impedances. For each designed coil, its stray parameters such as the inter-turn capacitance, coil resistance and capacitance between the coil and the core, etc. are taken into account. An equivalent circuit model of the designed coil is established. According to this equivalent circuit, the impedance characteristic of the coil is calculated. In addition, the maximum impedance point and the corresponding excitation frequency of the coil are obtained. Based on this analysis, six designed coils are adopted to isolate the interference from power delivery. The proposed method is verified through experiments with a power carrier frequency of 1MHz and a data carrier frequency of 8.7MHz. The power and data are transferred parrallelly with a data carrier attenuation lower than -5dB and a power attenuation on the sensing resistor higher than -45dB.

• Journal of Korean Society of Water and Wastewater
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• v.22 no.6
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• pp.647-655
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• 2008

Sewer Rehabilitation Project (SRP) is planed, designed and constructed to perform its intended performance as sewerage delivery systems. Recently, a subject of performance evaluation methodology development for SRP has become a great deal of concern among researchers in Korea. From the view point of Sewage Treatment Plant (STP), however, the estimation of improvement efficiency for SRP is in lack of reliability due to the fact that affections for the treatment efficiency and operating condition are not reflected on SRP design and construction. In this study, statistical methodology was used in the analysis of data, which are taken during 1,186 days ($1^{st}$ Jan. 2005 - $31^{th}$ Mar. 2008) from the influent, effluent and operating conditions of full-scale STP($25,000m^3/d$). Then the effect of SRP on the influent characteristics and operating conditions changing was compared and evaluated. Results from the statistical evaluation show that SRP causes characteristic changes in influent and exerts a significant effect especially on the performance of STP.

• International Journal of Advanced Culture Technology
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• v.11 no.4
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• pp.24-33
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• 2023

This research aimed to validate the Korean version of the Workforce Agility Scale (K-WAS) among care workers for community-dwelling frail elderly. The study involved 192 care workers from Gyengsangnam-do, who completed a structured questionnaire between May 31 and July 15, 2023. The K-WAS, a 13-item instrument measured on a 5-point Likert scale, captures three key aspects of workforce agility: proactivity, adaptability, and resilience. Confirmatory factor analysis was employed to ascertain the scale's construct validity. The K-WAS demonstrated a significant positive correlation with psychological empowerment (r=.560, p<.001), thereby establishing its criterion validity. Although the results suggest that the K-WAS is a valid and reliable tool for assessing workforce agility among care workers, further refinement is recommended. The K-WAS is anticipated to aid in the implementation and evaluation of interventions focused on enhancing workforce agility among care workers for frail elderly. By providing a valid and reliable measure of workforce agility, the K-WAS can facilitate the evaluation of these interventions' effectiveness in improving outcomes for the frail elderly and_ enhancing the overall quality of care delivery.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.6 no.8
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• pp.63-71
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• 1983

Aggregate planning coordinate the control variable over long-term to apply a demand variable and forcasting. In order to necessary the goal that doesn't make an inter-contradiction and explicitly defined. We made a considerable point of system approach for scheduling establishment. It include the control variables of aggregate planning : 1) employment 2) over time working and idle time 3) inventory 4) delivery delay S) subcontract 61 long - term facility capacity. Each variables composed of pure strategy as like a decision of inventory level, a change of employment level, etc. md alternative costs make a computation on the economic foundation. But the optimum alternative costs represent the mixed pure strategy. The faults of this method doesn't optimum guarantee a special scheduling as well as increasing a number of alternative combination. Theoretical, Linear Decision Rule make an including all variables, but it is almost impossible for this model to develope actually And also make use of the aggregate planning problem for developing system approach : LDR, heuristic model, Search Decision Rule, all kind of computers, simulation. But these models are very complex, each variables get an extremely inter-dependence. So this study be remained by theory level, some approach methods has not been brought the optimum solution to apply in every cases.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.198-203
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• 2004

In these days, the orthodontic surgery including lingual orthodontics has attracted a person' attention due to its functional and esthetic appreciation. The delivery of the optimal orthodontic treatment is greatly influenced by clinician' ability to predict and control the tooth movement by applying force system to dentition. The skeletal anchorage system with the miniscrew has been used recently in the lingual orthodontics to assist the anchorage control. Precise understanding of the force system produced from the various orthodontic appliances is necessary. However, the qualitative and quantitative effect of the miniscrew has not been identified well. In this paper, three dimensional finite element analysis is introduced on the lingual orthodontics to investigate the effect of anterior retraction force on the miniscrew and transpalatal arch wire. The purpose of this study is to determine the location of the miniscrew and the point of force application of the anchorage system in the lingual orthodontics. The analysis results indicate the efficient position of the miniscrew and the transpalatal arch wire in the lingual orthodontics.

• Journal of the Korea Institute of Military Science and Technology
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• v.15 no.6
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• pp.770-778
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• 2012

In this paper, we propose a multi-path construction scheme to improve the survivability of a multicast session in military hybrid networks. A military hybrid network consists of a static backbone network and multiple mobile stub networks where some nodes are frequently susceptible to be disconnected due to link failure and node mobility. To improve the survivability of multicast sessions, we propose a construction scheme of ${\kappa}$ redundant multi-paths to each receiver. In order to take account of different characteristics of static and mobile networks, we propose quite different multi-path setup approaches for the backbone and stub networks, respectively, and combine them at the boundary point called gateway. We prove that our proposed scheme ensures that each receiver of a multicast session has ${\kappa}$ redundant paths to the common source. Through simulations, we evaluate the performance of the proposed schemes from three aspects : network survivability, recovery cost, and end-to-end delay.

• Journal of the Ergonomics Society of Korea
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• v.31 no.2
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• pp.413-419
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• 2012

Objective: This study presents an observation and analysis on behavioral characteristics of old users in comparison to young users in the use of control on display interface. Background: Touch interface which allows users to control directly on display, is conceived as delight and easy way of human-computer interaction. Due to the advantage in stimulus-response ensemble, the old users, who typically experiencing difficulties in interacting with computer, would expected to have better experience in using computing machines. Method: Twenty nine participants who are over 50 years old and 14 participants who are in 20s years old were participated in this study. Three primary tasks in touch interface, which are tap, move, and flick, were delivered by the users. For the tap task, response time and point of touch response were collected and the response bias was calculated for each trial. For the move task, delivery time and the distance of finger movements were recorded for each trial. For the flick task, task completion time and flicking distance were recorded. Results: From the collected behavioral data, temporal and spatial differences between young and old users behavior were analyzed. The older users showed difficulty in completing move task requiring eye-hand coordination.

• Journal of Ubiquitous Convergence Technology
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• v.2 no.2
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• pp.88-96
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• 2008

IPTV Content delivery systems over wired networks confront scalability problems due to their high network bandwidth requirement for real-time services. Especially, VoD service provides Trick Mode features such as pause, fast forward and similar operations. However, Trick Mode services are delivered by the method of unicast only for controlling of the stream. With a point of views, this paper propose a new real-time multimedia streaming architecture over IP Networks, which tries to achieve bandwidth efficiency and supporting for mass clients better than traditional unicast services. The proposed methods divide the Transport Stream into a series of segments. After that, this divided partial Transport Stream makes multicast streaming periodically. Meanwhile Set-top Box of a client makes a rearrangement orderly by using Presentation Time Stamp field from the served Transport Stream packets. While the current Transport Stream segment is playing, it should be guaranteed that the next segment is downloaded on time. Consequently, the original video content can be played out continuously. The detail introduction of a new real-time multimedia streaming system with analysis and simulation follows as below.