• 생물정신의학
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• 제22권2호
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• pp.29-33
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• 2015

The brain maintains homeostasis and normal microenvironment through dynamic interactions of neurons and neuroglial cells to perform the proper information processing and normal cognitive functions. Recent post-mortem investigations and animal model studies demonstrated that the various brain areas such as cerebral cortex, hippocampus and amygdala have abnormalities in neuroglial numbers and functions in subjects with mental illnesses including schizophrenia, dementia and mood disorders like major depression and bipolar disorder. These findings highlight the putative role and involvement of neuroglial cells in mental disorders. Herein I discuss the physiological roles of neuroglial cells such as astrocytes, oligodendrocytes, and microglia in maintaining normal brain functions and their abnormalities in relation to mental disorders. Finally, all these findings could serve as a useful starting point for potential therapeutic concept and drug development to cure unnatural behaviors and abnormal cognitive functions observed in mental disorders.

• 비파괴검사학회지
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• 제32권6호
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• pp.696-702
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• 2012

In this study, a noncontact laser ultrasonic system is proposed for rail defect detection. An Nd-Yag pulse laser is used for generation of ultrasonic waves, and the corresponding ultrasonic responses are measured by a laser Doppler vibrometer. For the detection of rail surface damages, the shape of the excitation laser beam is transformed into a line. On the other hand, a point source laser beam is used for the inspection of defects inside a rail head. Then, the interactions of propagating ultrasonic waves with defects are examined using actual rail specimens. Amplitude attenuation was mainly observed for a surface crack, and reflections were most noticeable from an internal damage. Finally, opportunities and challenges associated with real-time rail inspection from a high-speed train are discussed.

• 기술혁신연구
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• 제12권2호
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• pp.47-66
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• 2004

The relationship between innovation policies and locational competitiveness has emerged as an important area in the analysis of economic development, reflecting both the centralisation and decentralisation of globalising economic activities. The underlying spatial and institutional components are subject to a pattern of cumulative causation in which strategic interventions of policy actors exercise a decisive role in shaping competitive advantages, while promoting interactions with local and foreign partners both from the private and public sectors. The Singaporean development experience illustrated these strategic interdependencies of innovation policies and locational competitiveness. Based on her role as a manufacturing and service hub, Singapore is viewed as an infrastructural nodal point which is interconnected to global production networks. Paralleling efforts in the domain of technological innovation, Singapore's policies for locational competitiveness aim at an adaptive harmonisation of the needs of international investors with local developmental objectives. This orientation characterises also current efforts in promoting Singapore as a knowledge agglomeration with a distinct science base, expanding R&D operations and an innovation-driven pattern of economic development. In conclusion, the locational rationale of Singapore's innovation policies provides lessons for dealing with the spatial and institutional implications of technological globalisation.

• 대한산업공학회지
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• 제19권3호
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• pp.103-111
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• 1993

There are four flexor muscles at elbow-biceps brachii, brachialis, brachioradialis, pronator teres. Muscle exertion force depends on the following conditions : elbow angle, external workload, and endurance time. The objectives of this study are to investigate the variations of the recruitment patterns of four muscles, and to analyze the changes of the role assigned to each muscle during elbow flexion. For three elbow angles, the transition point of type F motor unit of each muscle is inferred and the changes of the role assigned due to exertion level are identified by electromyographic analysis. The results showed that the recruitment pattern of biceps brachii is constant but those of other muscles are varied depending on elbow angle and exertion level. An EMG multiplexor is developed and simultaneous measurement of electromyographic signals of four elbow flexors is possible.

• 한국산업융합학회 논문집
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• 제3권1호
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• pp.43-51
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• 2000

The response statistics of a hinged-clamped beam under broad-band random excitation is investigated. The random excitation is applied at the nodal point of the second mode. By using Galerkin's method the governing equation is reduced to a system of nonautonomous nonlinear ordinary differential equations. A method based upon the Markov vector approach is used to generate a general first-order differential equation in the dynamic moment of response coordinates. By means of the Gaussian and non-Gaussian closure methods the dynamic moment equations for the random responses of the system are reduced to a system of autonomous ordinary differential equations. The case of two mode interaction is considered in order to compare it with the case of three mode interaction. The analytical results for two and three mode interactions are also compared with results obtained by Monte Carlo simulation.

• Journal of Astronomy and Space Sciences
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• 제10권2호
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• pp.152-162
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• 1993

이 연구에서는 태양계 천체들의 운동에 대한 역학 모델을 설정하고, 그에 적합한 운동 방정식을 수치 적분하여 임의의 시각에 각 행성과 달의 위치를 계산할 수 있도록 하였다. 이때 역학 모델에는 (1) 점질량 상호작용, (2) 지구와 달의 중력 포텐셜에 의한 figure효과, (3) 조석력, (4) 지구와 달의 orientation 등에 의한 섭동력 등을 모두 고려하였다. 그리고 이 프로그램을 이용해 계산한 결과를 미국의 JPL에서 생산한 DE200 자료와 비교 분석하였다.

• Steel and Composite Structures
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• 제2권3호
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• pp.223-236
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• 2002

An analytical procedure based on the transfer matrix method to estimate not only the natural frequencies but also vibration mode shapes of the thin-walled members composed of interconnected cylindrical shell panels is presented. The transfer matrix is derived from the differential equations for the cylindrical shell panels. The point matrix relating the state vectors between consecutive shell panels are used to allow the transfer procedures over the cross section of the members. As a result, the interactions between the shell panels of the cross sections of the members can be considered. Although the transfer matrix method is naturally a solution procedure for the one-dimensional problems, this method is well applied to thin-walled members by introducing the trigonometric series into the governing equations of the problem. The natural frequencies and vibration mode shapes of the thin-walled members composed of number of interconnected cylindrical shell panels are observed in this analysis. In addition, the effects of the number of shell panels on the natural frequencies and vibration mode shapes are also examined.

• Interaction and multiscale mechanics
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• 제1권4호
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• pp.437-448
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• 2008

This paper examined the stability of high-dense dislocation substructures (HDDSs) associated with martensite laths in High Cr steels supposed to be used for FBR, based on a series of dislocation dynamics (DD) simulations. The DD simulations considered interactions of dislocations with impurity atoms and precipitates which substantially stabilize the structure. For simulating the dissociation processes, a point defect model is developed and implemented into a discrete DD code. Wall structure composed of high dense dislocations with and without small precipitates were artificially constructed in a simulation cell, and the stability/instability conditions of the walls were systematically investigated in the light of experimentally observed coarsening behavior of the precipitates, i.e., stress dependency of the coarsening rate and the effect of external stress. The effect of stress-dependent coarsening of the precipitates together with application of external stress on the subsequent behavior of initially stabilized dislocation structures was examined.

• Tribology and Lubricants
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• 제14권1호
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• pp.54-63
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• 1998

In many practical lubricated contacts such as a rough concentrated contact on the sliding of nominally flat surfaces, the fluid may be of molecular (nanometer) scale owing to the asperity interactions on the surfaces. Under this condition, there is insufficient lubricant on the concentrated contact spot to maintain a realistic continuum. Rheological behavior for this kind of concentrated contact has been studied extensively to know whether the application of viscous fluid model is appropriate. The interaction of two rough surfaces is simplified as perfectly flat-rough surfaces contact under certain conditions by "composite topography" and for a nanometer scale fluid film, three kinds of rheological fluid behavior are analyzed in elastohydrodynamic asperity point contact.t contact.

• Journal of the Optical Society of Korea
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• 제18권6호
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• pp.799-808
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• 2014

The mechanism of optical interaction of two nanoholes, milled in an opaque gold film, by means of surface plasmon polariton (SPP) propagation is investigated. The interaction depends on the polarization direction of the incident light when the nanohole pair is illuminated through uniform single antenna excitations. It is shown that by illuminating one of the nanoholes, under single antenna excitation, the other nanohole can be excited indirectly via propagated SPPs from the excited nanohole. In addition, it is found that the spectrum of electromagnetic power above the surface of the metallic film at an arbitrary point along the axis of the nanohole pair presents two resonant peaks. These peaks are due to the optical interaction between nanoholes, where the short- and long-wavelength peaks can be assigned to in-phase and antiphase interactions of magnetic dipoles relative to each nanohole, respectively. The magnetic coupled dipole approximation (MCDA) method confirms the simulation results.