• Title/Summary/Keyword: Point Kinetics

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Studies on Steroid Hormone Concentration during the Estrous Cycle in the MediKinetics Micropig®

  • Seong, Hun-Ki;Seo, Kyeong-Seok;Kim, Jeong-Su;Her, Chang-Gi;Kang, Myung-Hwa;Sim, Bo-Woong;Yoon, Jong-Taek;Min, Kwan-Sik
    • Reproductive and Developmental Biology
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    • v.41 no.1
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    • pp.1-6
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    • 2017
  • In all mammalian species, progesterone is essential to both the preparation for, and maintenance of, pregnancy. The $20{\alpha}$-hydroxysteroid dehydrogenase ($20{\alpha}$-HSD) enzyme predominantly converts progesterone into its biologically inactive form $20{\alpha}$-hydroxyprogesterone, thereby regulating its activity. Thus, to directly assess sexual maturation in the MediKinetics $micropig^{(R)}$, we analyzed the concentration of the steroid hormones progesterone and estradiol during the estrous cycle. Our results show that the progesterone level exhibited by the analyzed $micorpig^{(R)}$ was low at the beginning of the estrous cycle, and then abruptly increased to $30.32{\pm}10.0ng/mL$ and $46.37{\pm}11.0ng/mL$ by days 9 and 11 of the cycle, respectively. It reached the highest level $55.87{\pm}3.5ng/mL$ on day 13 of the estrous cycle, before decreasing to $46.58{\pm}13.1ng/mL$ and $10.0{\pm}7.6ng/mL$ by days 15 and 17 of the cycle, respectively. In contrast, the estradiol level was shown to be highest ($27.13{\pm}11.2ng/mL$) at the initiation of the estrous cycle, after which point it decreased to $13.29{\pm}6.5ng/mL$ and $10.94{\pm}5.9ng/mL$ by days 4 and 5 of the estrous cycle, respectively. By day 17 of the estrous cycle, the estradiol level decreased to $4.13{\pm}7.6ng/mL$. We anticipate that these results will provide useful information to enable the study of human ovulation and reproductive physiology using the MediKinetics $micoripig^{(R)}$ as a model system. We recommend further investigation to elucidate the functional mechanisms underlying the regulation of sexual maturation in the MediKinetics $micropig^{(R)}$.

Application of the Equivalent Point Method for Estimation of Kinetic Parameters (Kinetic Parameters 결정을 위한 Equivalent Point Method의 이용)

  • Rhim, Jong-Whan
    • Korean Journal of Food Science and Technology
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    • v.22 no.5
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    • pp.582-589
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    • 1990
  • A method for application of the equivalent time and temperature point for estimating kinetic parameters was proposed. The feasibility of the method was demonstrated with both theoretical and empirical kinetic data. The theoretical kinetic data were obtained from the arbitrarily chosen time-temperature data for three chemical reactions whose kinetics are well established. The experimental kinetic data were obtained for the acid (0.0005 N HCl) catalyzed hydrolysis of sucrose(2%). The activation energy and the frequency factor determined by the proposed method were $104.74{\pm}1.87kJ/mol\;and\;5.62{\times}10^{14}\;hr^{-1}$ respectively and the results agreed well with those obtained by a different method of kinetic parameter estimation, i.e. the linearly increasing temperature method.

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Kinetics Change of the R-134a Gas Hydrate Formation in Seawater with the Addition of Edible Surfactants (R-134a 가스 하이드레이트 형성 속도에 미치는 식용 계면활성제 첨가의 영향)

  • Jeong, Hui Cheol;Kim, A Ram;Lim, Jun-Heok;Won, Yong Sun
    • Clean Technology
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    • v.22 no.3
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    • pp.154-160
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    • 2016
  • For any conceivable desalination process using the gas hydrate formation, the kinetics has to be one of the most important parameters from the economic point of view. We thus were to improve the kinetics of the R-134a (also known as HFC-134a) gas hydrate formation by using promoters and three different kinds of edible surfactants were selected for the desalination process targeted to produce potable water; κ-carrageenan, lecithin, and polysorbate 80 among anionic, amphoteric, and nonionic surfactants, respectively. Then, the kinetics change of the R-134a hydrate formation was monitored by varying the surfactant concentration. Experimental results demonstrated that the rate of R-134a hydrate formation increases with the addition of edible surfactants in general and the effect as a promotor has an order of polysorbate 80 > κ-carrageenan > lecithin. As a supportive measure, the atomic charges of each surfactant were calculated by using a DFT (density functional theory)-based molecular modeling and the results showed a positive relationship between the promotor effect of each surfactant and the number of oxygens available for hydrogen bonding and the negativity of their atomic charge values.

Analysis for Force Distribution on Surface Between Busbar Contacts (부스바 접점 가동시 접촉면에서 압점력 해석)

  • Oh, Y.H.;Song, K.D.;Kim, K.S.;Kim, J.K.
    • Proceedings of the KIEE Conference
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    • 2003.04a
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    • pp.82-84
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    • 2003
  • In case contact between point of contacts is not achieved well, contact resistance is grown, and by current concentration at current conducting contacts can weld. In order to decrease contact resistance between contacts in case of busbar, installing spring between fixed contact and moving contact. and then force on faying surface of contacts increase and contact resistance decrease. But, in case increase force of spring to widen contact area, operating force moving contact can grow, on the contrary force of spring is small, contact resistance becomes low. Therefore, need to optimize force and number of spring. position, and also need to examine force change on contact surface at point of contact moving. In this paper, dynamic kinetics analysis for force on faying surface of contacts is performed at unsteady state. It is showed to not uniform force on surface between contacts, and we can got more uniform force by means of change spring position.

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Multiple Unstable Modes in the Reacting Mixing Layer (반응혼합층의 복수 불안정성 모드)

  • Sin, Dong-Sin
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.2
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    • pp.616-623
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    • 1996
  • This paper investigates the linear stability of reacting mixing layers with special emphasis on the existence of multiple unstable modes. The governing equations for laminar flows are from two-dimensional compressible boundary-layer equations. The chemistry is a finite rate single step irreversible reaction with Arrhenius kinetics. For the incompressible reacintg mixing layer with variable density. A necessary condition for instability has been derived. The condition requires that the angular momentum, not the vorticity, to have a maximum in the flow domain. New inflectional modes of instability are found to exist in the outer part of the mixing layer. For the compressible reacting mixing layer, supersonic unstable modes may exist in the abscence of a generalized inflection point. The outer modes at high Mach numbers in the reacting mixing layer are continuations of the inflectional modes of low Mach number flows. However, the generalized inflection point is less important at supersonic flows.

The Relaxation and Elimination Characteristics of Polarization-Photoinduced Dichrosim in Obliquely Deposited Amorphous Chalcogenide Thin Films (경사 증착된 비정질 칼코게나이드 박막에 평광-광유기된 이색성의 이완 및 소거 특성)

  • Park, Soo-Ho;Chun, Jin-Young;Lee, Hyun-Yong;Chung, Hong-Bay
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.11 no.10
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    • pp.891-896
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    • 1998
  • The relaxation and elimination characteristics of polarization-photoinduced dichroism have been investigated in amorphous chalcogenide thin films deposited having normal(0。) and obique (80。) vapor incident angles. The dark relaxation kinetics of dichroism from a saturation point(D\ulcorner\ulcorner) to a certain relaxation point(D\ulcorner\ulcorner) grew to be longer on subsequent cycles of switching on and off of the inducing light, and these decays are changed from simple exponential decay to stretched exponential decay. The dichroism induced by a long time(~3.3 hrs) exposure exhibited the characteristics of longer time maintenance and smaller decreasing rate, in contrast with that by a short time (~min) exposure. In addition, the dichroism was eliminated by the exposure of non-polarized He-Ne laser.

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Miscibility and Properties of cis-Polybutadiene/Ethyl-Branched Polyethylene Blends (II)

  • Cho, Ur-Ryong
    • Macromolecular Research
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    • v.8 no.2
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    • pp.66-72
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    • 2000
  • Cis-Polybutadiene (cis-PBD) and the three polyethylenes (PE's) having different branch content were mixed to investigate crystallinity, thermodynamic interaction parameter(c), and diluents effect. Crys-tallinty of PE's decreased with increasing content of amorphous cis-PBD because of a decrease in both the degree of annealing and kinetics of diffusion of the crystallizable polymer content. The thermodynamic interaction parameter(c) for the three blend systems approximately equals to zero near the melting point. These systems were determined to be miscible on a molecular scale near or above the crystalline melting point of the crystalline PE's. From the measurement of T$\sub$m/ vs. T$\sub$c/ behavior, all the three blends showed a straight line for a plot of T$\sub$m/ vs. T$\sub$c/. This result means that the melting behavior of PE is mainly due to a diluent effect of cis-PBD component.

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REACTIVITY OSCILLATION IN SOURCE-DRIVEN SYSTEMS

  • Dulla, S.;Nicolino, C.;Ravetto, P.
    • Nuclear Engineering and Technology
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    • v.38 no.7
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    • pp.657-664
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    • 2006
  • The problem of reactivity oscillations for a point reactor constitutes an interesting aspect of nuclear reactor physics and its solution may give important information for dynamic and safety assessments. The present paper considers the problem of a reactivity oscillation for a source-driven system which involves some specific aspects that introduce significant differences with respect to the source-free situation. Assuming a square-wave shape for the reactivity insertion, the solution is derived by a fully analytical approach. The conditions for stability and instability can be identified in a straightforward way by directly studying the stationarity of the power response. Numerical results presented allow to discuss the role of the system kinetic parameters and of the time-shape of the reactivity wave.

Kinetics of Chromium(III) Oxidation by Various Manganess Oxides (망간 산화물에 의한 3가 크롬의 산화)

  • Chung, Jong-Bae;Zasoski, Robert J.;Lim, Sun-Uk
    • Applied Biological Chemistry
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    • v.37 no.5
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    • pp.414-420
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    • 1994
  • Birnessite, pyrolusite and hausmannite were synthesized and tested for the ability to oxidize Cr(III) to Cr(VI). These oxides differed in zero point of charge, surface area, and crystallinity. The kinetic study showed that Cr(III) oxidation on the Mn-oxide surface is a first-order reaction. The reaction rate was various for different oxide at different conditions. Generally the reaction by hausmannite, containing Mn(III), was faster than the others, and oxidation by pyrolusite was much slower. Solution pH and initial Cr(III) concentration had a significant effect on the reaction. Inhibited oxidation at higher pH and initial Cr(III) concentration could be due to the chance of Cr(III) precipitation or complexing on the oxide surface. Oxidations by birnessite and hausmannite were faster at lower pH, but pyrolusite exhibited increased oxidation capacity at higher pH in the range between 3.0 and 5.0. Reactions were also temperature sensitive. Although calculated activation energies for the oxidation reactions at pH 3.0 were higher than the general activation energy for diffusion, there is no experimental evidence to suggest which reaction is the rate limiting step.

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A Study on the thermal Kinetics for Disposal of Sewage Sludge Using Thermal Wind Drying of One mechanical Power (ONE구동 열풍건조시스템을 이용한 하수슬러지 감량화를 위한 열적거동 연구)

  • Bae, Hae-Ryong;Ha, Sang-An
    • Journal of the Korea Organic Resources Recycling Association
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    • v.13 no.2
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    • pp.74-84
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    • 2005
  • The objectives of this study was to investigate the improvement of thermal kinetics for disposal of sewage sludge using thermal wind drying. The operational parameters varied are the temperature of $130{\sim}170^{\circ}C$ and evaporation velocity WD. Important parameters effect on thermal kinetics for evaporation of water in sewage sludge studied include the drying time, water content of sewage sludge, solids amount of sewage sludge(TS%) by the varied temperature. The saturation point of water evaporation was observed at the drying time of 60 min in conditions of drying temperature $170^{\circ}C$ and drying time of 120 min by drying temperature $130^{\circ}C$ and WD=0.95 m/s. Operation at drying temperature of $170^{\circ}C$ led to higher rate of evaporation than those 130, $150^{\circ}C$ at WD=1.0 m/s and WD=1.0 m/s was higher than WD=0.5 m/s at drying temperature of $130^{\circ}C$.

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