• Journal of Life Science
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• v.14 no.5
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• pp.732-740
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• 2004

MCM proteins are essential for eukaryotic DNA replication, playing roles in the initiation and elongation of DNA replication. MCM proteins expression is much higher in malignant tissues than normal tissues. Several reports have indicated the usefulness of MCM proteins as markers of cancer cells in histopathological diagnosis. However, the cause of enhanced expression of MCM proteins in cancer cells remain to be clarified. The purpose of this study is to examine the relative transcriptional activities of human mcm gene promoters in cancer and normal cells. The minimal promoter region required for transcription of a luciferase reporter gene was contained an E-box and one E2F site. In addition, luciferase activities from mcm7 and mcm2 promoter/luciferase gene reporter constructs were significantly increased in cancer cells at 8 times compared with normal cells. E-box and E2F binding site in the promoter of mcm genes are responsible for different mechanism of transcription regulation on the cellular environment.

• Korean Journal of Hospice Care
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• v.2 no.1
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• pp.182-192
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• 2002

Childhood Cancer Foundation of ROC(CCFROC) has been founded since 1982. Its goal is to provide comprehensive care for cancer children and their families. And in turn, under the provision of good and complete care, they can be back to the school and society. To achieve this goal, it needs to get every body's effort of the society together. The foundation has been founder under this concept and tried to fulfil this task. The first step is to educate the public to know that childhood cancer can be cured and the process of treatment is long and expensive. In order to reach this life-saving procedure, campaigns for raising money is most important thing. Then, pediatric hematologists / oncologists try to organize study group, named Taiwan Pediatric Qncology Goupp(TPOG), to make treatment protocols for childhood cancers. Its primary purpose is to increase the cure rate to prove the earlier the diagnosis and treatment, the better the prognosis. The second step is to provide full support of medical expenses and further to give help for emergent need to living. Through the varieties of active exercises of cancer children or families, foundation provides opportunities for them to share the experience during the different periods of diseases. The third step is to extend the scope of training activities for many kinds of personnel who devote to the care for cancer children. On the other hand, it promotes the cooperation or communication with international organizations and sets up recreation playing ground in the communities. The aim is to provide a comprehensive and integrated care for cancer children during their education, breeding and even accomplishment period. Besides the financial support of medical care, it provides social services to give psychological support for children and their families, to strengthen doctor-patients or doctor-families relationship. The foundation provides the mourning religious activities to cherish the memory of their children who passed away and to comfort their sadness. Since the childhood cancer is curable, its treatment should be active, comprehensive and it needs to provide to all cancer children without exception. Indeed, the work of CCFROC should be changed according to the environment and different time period. But, it needs the full support from the society. We hope the scope and content of the work will be more extended and its achievement will be better than now in the future.

• The Journal of Korean Association of Computer Education
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• v.14 no.6
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• pp.31-39
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• 2011

Information and communication environment includes a lot of dangerous factors to elementary school children who do not establish their own value sense as well as its related knowledge yet. This paper proposes a case based multiplex teaching and learning model which leads students to participate and be interested in, then to improve the educational level of information and communication ethics in elementary school. This model progresses in centric of the conflict situations in information and communication ethics that can be commonly occurred in actual life. To adapt case based approach, three types of teaching and learning models, value conflict, value clarification, and role playing, are applied in a combined form. Along with applying the models, their educational effects have been compared and analysed in time sequence, in the educational level improvement point of view. The verification has been conducted by using surveys and questionnaires, in the four areas; cognitive, affective, behavioral, and then overall. The verification results show that the proposed method is effective to improve the educational level of information and communication ethics in elementary schooll.

• Journal of the Korean housing association
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• v.25 no.3
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• pp.1-12
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• 2014

Korean traditional house has inherented construction characteristics that contain human requirements with the adaptation to nature's order. As for traditional buildings, there are a lot of facilities like palaces, Buddhist temples, Confucianism architectures, government facilities, etc. Among them, housing construction is not only closely connected to our lives, but also plays an important role to connect our lives from the past to present. The master room in a traditional korean house is responsible for playing a center role of the residential life which implies the traditional values responsible for multi-functions and it is also the sphere of the living space. Therefore, this thesis considers the residential environmental adjustment method and the behaviors centered around the main buildings of Jeonnam Province. And also investigates the main reason for windows and doors formation. From this, we would like to further evaluate the master room life, and the inner space constructions following the spacial and organizational analysis of windows and doors. We would like to analyze the space organization methods, environmental adjustment methods and the usages of traditional buildings. Using the modern interpretation as basis, we would like to use the foundation materials to reflect single family housing plans.

• Korean Institute of Interior Design Journal
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• v.20 no.4
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• pp.74-82
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• 2011

All the phenomena and subjects of nature and society are within correlation interconnection, and they are inseparably connected one another. The elements of this interaction can be found out through the concept of transparency in the space composition of Korean traditional architecture. This study is focusing on the access space, in other words, a gate-house that is a buffer zone playing a process role up to the main space among successive spaces. It was chosen to be the subject of the study since it strengthens convergence into the main building and with the effect connecting spaces, it could show well the spatial possibility of transparency. Besides, the subject of the study is limited to the Moonru Multi roofs that improves the functionality of spaces between gate-houses, and it is intended to progress contents by comparative analysis of two kinds such as Seo Won gate-house and temple gate-house. Korean traditional architecture places emphasis on harmony within the whole spaces. There are intimate relations between surrounding environment, external spaces and internal spaces, and it is important understand the spatial relations according to the shape appearing through interactions of parts in the whole spaces. In conclusion, the Moonru Multi roofs is analyzed with the method of extracting the concept that is contained in the frame of analysis and through ecological views through a visible and structural method. It can be understood what kinds of method for communication were used for ancestors to recognize and use spaces with the deduced concept through the analysis of the Moonru Multi roofs with different character.

• Journal of The Association for Neo Medicine
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• v.2 no.2
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• pp.253-295
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• 1997

It is very critical to specify certain medical personnels in defining the history of certain era. Due to the limited source of information and lack of thorough research, there still aren't enough study grounded on concrete historical investigation. Authors attempted to investigate those medicinal personnels engaged in Three Kingdoms period in terms of the activity area, relation with religion and their role in medical system and medical exchange. The sum of recorded medical personnels in Three Kingdoms period numbers 50 of which 6 belonged to Kokooryo, 18 to Baekje, 7 to Shilla and 19 to Unified Shilla. There might existed far more medical personnels who tried to alleviate the suffering of the people and were not recorded in the documents. The more earlier in times, the more medicine gets the religious tinge. This is not the exception for the period of the Three Kingdoms and those medicine men, wizard doctors and priest doctors were playing important role in healing people and processing crude drugs. The system of royal physician and medical education facility were established and doctors and pharmacists, shamanic doctor, herb collectors, Kongbong's doctor(供奉醫師), Kongbong's diviners(供奉卜師) took leads in medicine in those times. Those folkloric healers also took part in. Korea imported chinese medicine and Japan employed chinese medicine via Korea or directly from China and developed into traditional japanese medicine. In this process those who emigrated from Baekje and Kogooryo and their offsprings took an active part. Since the limited source of information of Three Kingdoms, we only can infer the me야cal environment of those times by featuring the activities of medical personnels.

• Journal of Korea Multimedia Society
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• v.3 no.4
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• pp.389-398
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• 2000

The focus of this study is to investigate how personal display system - Head Mounted Display(HMD) and VDU-affect to the body in virtual environments. This prediction was tested by a comparing of playing 3D games while wearing a HMD and monitoring a VDU for an hour. As quantitative measuring and analyzing tools, SSQ, RSSQ, pre and post posture stability test and vision test are used. The results showed that SSQ and RSSQ total score (TS) are related with the results of pre and post posture stability test and SSQ and RSSQ TS of HMD is higher than TS of VDU by one point five times. Especially, TS of MRG3C, having large field of view, has a possibility by two times of simulator sickness (SS). And in order to investigate the degree of SS regarding to the simulator control condition, two conditions, subjective-passive and subjective-active environments were compared. However, there was no significant difference between two environments. The repetition of the same environment has no effect to reduce the SS. Disorientation and oculomotor scores of the SSQ and RSSQ are higher than that of another symptoms. In addition, RSSQ score of strain/confusion is higher than that of nausea. Therefore, we assume that personal fear could possibly increase the simulator sickness in virtual environments.

• Journal of Biomedical Engineering Research
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• v.26 no.6
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• pp.399-406
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• 2005

In these days, HIS(Hospital Information System) raise the quality of medical services by effective management of medical records. As computing environment was developed, it is possible to search information quickly. But, standard medical data exchange is not completed between medical clinic and another organ so far. In case of patient transfer, past medical record was not efficiently transmitted. It be feasible treatment delay or medical accident. It is trouble that medical records is transferred by a person and communicate with each other. Extensible Markup Language (XML) is a simple, very flexible text format derived from SGML. Originally designed to meet the challenges of large-scale electronic publishing, XML is also playing an increasingly important role in the exchange of a wide variety of data on the Web and elsewhere. Form in system of company product, relative organs that handle bio-signal data is each other dissimilar and integration and to transmit to supplement bottleneck this research uses XML. In this study, it is discussed about sharing of medical data using XML web technology to standard medical record between hospital and relative organization The data structure model was designed to manage bio-signal data and patient record. We experimented about data transmission and all-in-one between different systems (one make use of MS-SQL database system and the other manage existent bio-signal data in itself form in file in this research). In order to search and refer medical record, the web-based system was implemented. The system that can be shared medical data was tested to estimate the merits of XML. Implemented XML schema confirms data transmission between different data system and integration result.

• Journal of the Society of Disaster Information
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• v.10 no.3
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• pp.466-480
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• 2014

In addition to aging social problem, the problem of older age structure ratio in the fire service organization playing the leading role of the disaster response activities is also expected to be this serious situation. In the case of Seoul fire fighting organization, it is expected that the ratio of over the age 50 reaches 31% or 40% between from 10 to 15 years later from now on, but this will be a serious problem in the fire fighting personnel needing a healthy body and physical strength in the disaster situation unlike the civil servants of general staff. Therefore, the purpose of this study is to take measures that can adapt to a new disaster environment of Increasing proportion of the elderly population by presenting the criteria of age limit of fire fighting field activities to analyze the relevance of the ability to perform on-site activities and age of Seoul fire civil servants, by using three analysis criteria.

• Journal of Broadcast Engineering
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• v.8 no.1
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• pp.63-71
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• 2003

In sport programs, real-time virtual imaging system come into notice for new technology which can compose information like team logos, scores. distances directly on playing ground, so it can compensate for the defects of general character generator. In order to synchronize graphics to camera movements, generally two method is used. One is for using sensors attached to camera moving axis and the other is for analyzing camera video itself. KBS technical research institute developed real-time sensor-based virtual imaging system 'VIVA', which uses four sensors on pan, tilt, zoom, focus axis and controls virtual graphic camera in three dimensional coordinates in real-time. In this paper, we introduce our system 'VIVA' and it's technology. For accurate camera tracking we calculated view-point movement occurred by zooming based on optical principal point variation data and we considered field of view variation not only by zoom but also by focus. We developed our system based on three dimensional graphic environment. so many useful three dimensional graphic techniques such as keyframe animation can be used. VIVA was successfully used both in Busan Asian Games and 2002 presidential election. We confirmed that it can be used not only in the field but also in the studio programs in which camera is used within more close range.