• Korean Journal of Clinical Laboratory Science
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• v.38 no.1
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• pp.1-8
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• 2006

The purposes of this study were to evaluate the changes in hematologic indices after plateletpheresis and to identify the preapheresis platelet count and clinical factors (age, gender, height, and weight) that showed some influence on the percentage of platelet decrement, yield and efficiency. Plateletpheresis was performed on 101 healthy donors in Bundang CHA general hospital. The data was analyzed using the SAS program with t-test, ANOVA test and Multiple regression. The mean percentage decrease after plateletpheresis was 2.0% in hemoglobin, 1.8% in hematocrit, and 29.7% in the platelet count, while a WBC count showed an increase of 2.6%. The mean percentage decrease of hemoglobin and hematocrit were 1.7% and 1.4%, in males and 3.6% and 3.7% in females, respectively. Particularly the percentage decrease of platelet count was significantly higher in females (40.0%) than in males (27.2%). The platelet decrementage and yield were significantly higher in females, but the efficiency did not differ significantly between males and females. The yield showed the lowest levels in subjects who were 40 years old or over but the platelet decrement and efficiency did not change according to age. The platelet decrement increased as height and weight increased. Also, the platelet decrement and yield increased as the initial platelet counts increased, but the efficiency did not. From multiple regression analysis, the platelet decrement was associated with gender, weight, and initial platelet count. The yield was related to the initial platelet count, but the efficiency was not related to gender, age, weight, height or initial platelet counts. This study has a limitation of the generality of the study results since this study was conducted only in a single university hospital. Further study would be necessary to find out a subpopulation that is sensitive to the hematologic change after plateletpheresis, and to determine the standard criteria for blood donation based on the subpopulation.

• Journal of Life Science
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• v.24 no.9
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• pp.1030-1038
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• 2014

Platelet products are used to treat hemorrhagic or platelet dysfunction diseases. Plateletpheresis involves collecting the platelet components of blood using an apheresis blood-collection system. Various indicators are available for evaluating the qualities of the apheresis platelets. The productivity of platelet collection is evaluated through both the collection efficiency and collection rates. Platelet storage quality can be evaluated in vitro using several indicators, including visual appearance, metabolic activities, volume, platelet count, white blood cell count, microparticles, and various platelet activation markers. Platelet activation markers have been used as indicators of storage quality in various studies. Post-transfusion platelet quality can be evaluated based on the corrected count increment and the percentage of platelet recovery. Although various studies have investigated the aspects of plateletpheresis, no article has systemically presented assessments of the platelet products obtained from different plateletpheresis devices. The present study provides a review of plateletpheresis, including the specifics of the process, the types of devices employed, the platelet quality, the overall efficacy, and the evaluation indicator qualities. Furthermore, the differences in functionality among the different apheresis devices are discussed. Although adverse reactions to the citrate anti-coagulant have been reported, apheresis processing may provide a safer option for donors who are at a high risk for presyncopal or syncopal reactions related to whole blood collection.

• Journal of Korean Academy of Nursing
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• v.27 no.3
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• pp.577-587
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• 1997

Purpose : To collect and interpret basic data involving the discomfort level of platelet donors and to see which nursing interventions would help make plateletpheresis more comfortable. Methods : Using "the Platelet Donor's Discomfort Scale" developed by the researcher herself and reviewed by an expert panel, the severity of discomfort as well as factors contributing to the development of this discomfort were analyzed. This scale contained 59 items and each item was scored by the 4-point Likert manner. Between March 1, 1996 and May 31, 1996, 500 platelet donors(16 years of age and older) were enrolled in this study. The Statistical methods used were factor analysis, t-test, and ANOVA. The results were as follows : 1. The mean of the platelet donor's discomfort scale was 130, range 69-207, possible score ranging from 59-236. 2. The platelet donor's discomfort scale had psychological, environmental, physical, and time-related factors. The time- related factor was the highest positive correlation with the development of the discomfort. 3. In looking at the psychological and environmental factors of the discomfort scores, the 16-20 age group had significantly higher ratings than those of the 26-30 age group. The students' group had higher scores than the soldier's group, and those who used the V-50, MCS -3P, or the PCS Plus machines had higher scores than those who used the COBE Spectra machine(P<.05, respectively), 4. In relation to the physical factor of the discomfort score, the youngest group felt significantly more discomfort, the student's group had a higher score than the soldier's group, and those who used the V-50, MCS-3P, or or the PCS Plus machines had higher scores than those who used the COBE Spectra machine(P<.05, respectively). 5. The time related factor of the discomfort score had the highest scores in every variable, however, statistically significant differences were not found between any of the variables(P>.05). Conclusion : Based on the above results, it can be oserved that the time-related factor was the most important factor influencing discomfort. The age and job of the donor, as well as the type of machine used, were significant variables in predicting the level of discomfort, regardless of psychological, environmental, and physical factors. This data could be used to determine nursing interventions that would relieve some of the discomfort of patients, as well as donors, undergoing plateletpheresis. Furthermore, consideration of the donor's time, introduction of a platelet donor pool system, publicity and education about platelet donation are required.

• Research in Community and Public Health Nursing
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• v.8 no.1
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• pp.21-30
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• 1997

The purpose of the study is to establish the nurses engaged in blood donation business right cognition and supply base data to make out proper directed blood donation rule through investigation of actual condition and general issue related to directed blood donation. In this study I searched for related reference and computed the directed blood donors in seoul national university hospital blood bank. The directed blood donation in Korea have been increased for supplying fresh whole blood and plateletpheresis donor blood. The most blood donation in the blood bank belong to hospital are directed blood donation. The benefits of directed blood donation are enlargement blood donor, easy insurance a demand type of blood. But that program also give rise to recipient severe burden, additional cost and confused blood donation system. First of all for lessening the burden of the recipient and the directed blood donor, blood donation site, time, cost and procedure must be repared by proper rules. An alternative plans for the directed blood donation are autologous blood program and donor registration system.