• 제목/요약/키워드: Plasticity development

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Synaptic Plasticity in Angelman Syndrome

  • Chung, Lee-Yup
    • 한국발생생물학회지:발생과생식
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    • 제16권3호
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    • pp.169-175
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    • 2012
  • Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability and autism. The genetic cause is the absence of UBE3A, an E3 ubiquitin ligase, from the maternal chromosome which can arise from multiple origins. Recently discovered targets of Ube3a are important for activity dependent changes in synaptic transmission and spine morphology. Plasticity studies in an AS mouse model is important for basic plasticity research with regard to understanding protein homeostasis as well as the search for therapeutic targets for the patients. The progress on synaptic plasticity from this unique disorder is reviewed.

간단한 현상학적 구성방정식의 고속 유동응력 기술 능력 (Description Capability of a Simple Phenomenological Constitutive Model for High-Strain-Rate Plasticity Data)

  • 신현호;김종봉
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2009년도 추계학술대회 논문집
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    • pp.190-193
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    • 2009
  • A recently reported simple phenomenological constitutive model (SK) demonstrated comparable or better data description capability to/than one of the rigorous and physics-based models, the PTW model. The simple SK model is believed to be an efficient model for practical applications where an extensive computation is needed, and can serve as a rigorous comparison standard for the development of a physics-based model.

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시냅스 가소성에 관한 고찰 (Review of Synaptic Plasticity)

  • 김석범;김진상
    • The Journal of Korean Physical Therapy
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    • 제13권1호
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    • pp.229-235
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    • 2001
  • Clinical interest has lately been roused by evidence that comprehension of synaptic plasticity may be based on the theoretical opinion. This paper describes perception of synaptic plasticity. Especially processes of long term potentiation(LTP) and long term depression(LTD) are discussed. Recently, it is assessed to genetical parts from development of molecular biology. Therefore this review also represents aspect of molecular events of synaptic plasticity.

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결정소성 유한요소법을 이용한 FCC 다결정 금속의 압연 집합조직 예측 (Prediction of Rolling Texture Evaolution in FCC Polycrystalline Metals Using Finite Element Method of Crystal Plasticity)

  • 박성준;조재형;한흥남;오규환
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 1999년도 제3회 압연심포지엄 논문집 압연기술의 미래개척 (Exploitation of Future Rolling Technologies)
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    • pp.313-319
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    • 1999
  • The development of deformation texture in FCC polycystalline metals during rolling was simulated by the finite element analysis using a large-deformation, elaatic-plastic, rate-dependent polycrystalline model of crystal plasticity. Different plastic anisotropy due to different orientation of each crystal makes inhomogeneous deformation. Assuming plane strain compression condition, the simulation with a high rate sensitivity resulted in main component change from Dillamore at low rate sensitivity to Brass component.

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단결정 밀리 부품의 입체성형 해석에 관한 연구 (A Study on Analysis for Bulk Forming of a Single Crystal Milli-Product)

  • 이용신;김용일
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2001년도 춘계학술대회 논문집
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    • pp.245-249
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    • 2001
  • This paper is concerned with numerical analyses for bulk forming of a single crystal milli-product, whose typical size ranges from a few hundreds ${\mu}m$ to a few mm. The numerical formulation invoked in this paper combines the crystal plasticity theory considering texture development and the ductile damage mechanics for growth of micro voids, since orientation development and growth of micro voids become the primary factors for bulk forming of milli-size products. As applications, milli-extrusion of a single crystal round bar and milli-rolling of a single crystal plate are simulated and the results are discussed in detail.

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밀리봉의 압출/인발의 유한요소해석 (Finite Element Analysis for Extrusion/Drawing of Milli-Size Bar)

  • 김용일;이용신
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2000년도 추계학술대회 논문집
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    • pp.70-73
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    • 2000
  • A finite element analysis model is suggested for analysis of forming process of milli structure whose size is from a few hundreds ${\mu}m$ to a few mm. In this paper, finite element formulation which assemble crystal plasticity theory considering texture development with damage mechanics is developed, since orientation development and growth of micro voids became the primary factors for deformation aspects in large deformation of milli structure. Applying to, extremely, extrusion process of single crystal and extrusion/drawing process of polycrystal milli-size bar, extrusion force, preferred orientation, and damage evolution are examined to understand the characteristics of deformation of milii-size bar.

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