• Development and Reproduction
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• v.16 no.3
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• pp.169-175
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• 2012

Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability and autism. The genetic cause is the absence of UBE3A, an E3 ubiquitin ligase, from the maternal chromosome which can arise from multiple origins. Recently discovered targets of Ube3a are important for activity dependent changes in synaptic transmission and spine morphology. Plasticity studies in an AS mouse model is important for basic plasticity research with regard to understanding protein homeostasis as well as the search for therapeutic targets for the patients. The progress on synaptic plasticity from this unique disorder is reviewed.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.04a
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• pp.45-53
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• 2002

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2005.05a
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• pp.340-340
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• 2005

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.10a
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• pp.190-193
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• 2009

A recently reported simple phenomenological constitutive model (SK) demonstrated comparable or better data description capability to/than one of the rigorous and physics-based models, the PTW model. The simple SK model is believed to be an efficient model for practical applications where an extensive computation is needed, and can serve as a rigorous comparison standard for the development of a physics-based model.

• The Journal of Korean Physical Therapy
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• v.13 no.1
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• pp.229-235
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• 2001

Clinical interest has lately been roused by evidence that comprehension of synaptic plasticity may be based on the theoretical opinion. This paper describes perception of synaptic plasticity. Especially processes of long term potentiation(LTP) and long term depression(LTD) are discussed. Recently, it is assessed to genetical parts from development of molecular biology. Therefore this review also represents aspect of molecular events of synaptic plasticity.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1999.08a
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• pp.313-319
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• 1999

The development of deformation texture in FCC polycystalline metals during rolling was simulated by the finite element analysis using a large-deformation, elaatic-plastic, rate-dependent polycrystalline model of crystal plasticity. Different plastic anisotropy due to different orientation of each crystal makes inhomogeneous deformation. Assuming plane strain compression condition, the simulation with a high rate sensitivity resulted in main component change from Dillamore at low rate sensitivity to Brass component.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2001.05a
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• pp.245-249
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• 2001

This paper is concerned with numerical analyses for bulk forming of a single crystal milli-product, whose typical size ranges from a few hundreds ${\mu}m$ to a few mm. The numerical formulation invoked in this paper combines the crystal plasticity theory considering texture development and the ductile damage mechanics for growth of micro voids, since orientation development and growth of micro voids become the primary factors for bulk forming of milli-size products. As applications, milli-extrusion of a single crystal round bar and milli-rolling of a single crystal plate are simulated and the results are discussed in detail.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2000.10a
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• pp.70-73
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• 2000

A finite element analysis model is suggested for analysis of forming process of milli structure whose size is from a few hundreds ${\mu}m$ to a few mm. In this paper, finite element formulation which assemble crystal plasticity theory considering texture development with damage mechanics is developed, since orientation development and growth of micro voids became the primary factors for deformation aspects in large deformation of milli structure. Applying to, extremely, extrusion process of single crystal and extrusion/drawing process of polycrystal milli-size bar, extrusion force, preferred orientation, and damage evolution are examined to understand the characteristics of deformation of milii-size bar.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2001.10a
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• pp.375-375
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• 2001

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2002.11a
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• pp.51-62
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• 2002