• Journal of Genetic Medicine
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• 제12권2호
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• pp.66-71
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• 2015

Down syndrome screening with cell-free DNA (cfDNA) in the maternal plasma has recently received much attention in the prenatal diagnostic field. Indeed, a large amount of evidence has already accumulated to show that screening tests with cfDNA are more sensitive and specific than conventional maternal serum and/or ultrasound screening. Globally, more than 1,000,000 of these noninvasive prenatal tests (NIPTs) have been performed to date. There are several different methods for NIPTs that are currently commercially available, including shotgun massively parallel sequencing, targeted massively parallel sequencing, and single nucleotide polymorphism (SNP)-based methods. All of these methods have their own advantages and disadvantages. In this review, I will focus specifically on the SNP-based NIPT.

• 한국레이저가공학회지
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• 제6권2호
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• pp.27-33
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• 2003

A laser shock cleaning technology is a new dry cleaning methodology for the effective removal of small particles from the surface. This technique uses a plasma shock wave produced by a breakdown of air due to an intense laser pulse. In order to optimize the laser shock cleaning process, it needs to evaluate the cleaning performance quantitatively by using a monitoring technique. In this paper, an acoustic monitoring technique was attempted to investigate the laser shock cleaning process with an aim to optimize the cleaning process. A wide-band microphone with high sensitivity was utilized to detect acoustic signals during the cleaning process. It was found that the intensity of the shock wave was strongly dependent on the power density of laser beam and the gas species at the laser beam focus. As a power density was larger, the shock wave became stronger. It was also seen that the shock wave became stronger in the case of Ar gas compared with air and N$_2$ gas.

• 생물정신의학
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• 제7권1호
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• pp.21-33
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• 2000

As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little clinical significances, some may interfere with treatment or even be life-threatening. This review provides a better understanding of drug-drug interactions often encountered in pharmacotherapy of depression. Drug interactions can be grouped into two principal subdivisions : pharmacokinetic and pharmacodynamic. These subgroups serve to focus attention on possible sites of interaction as a drug moves from the site of administration and absorption to its site of action. Pharmacokinetic processes are those that include transport to and from the receptor site and consist of absorption, distribution on body tissue, plasma protein binding, metabolism, and excretion. Pharmacodynamic interactions occur at biologically active sites. In this review, emphasis is placed on antidepressant medications, how they are metabolized by the P450 system, and how they alter the metabolism of other drugs. When prescribing antidepressant medications, the clinician must consider the drug-drug interactions that are potentially problematic.

• 한국세라믹학회지
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• 제35권1호
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• pp.41-47
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• 1998

Cutting and planarization of diamond films have been performed using copper vapor laser under air at-mosphere. Diamond films of about 350${\mu}{\textrm}{m}$ and 800 ${\mu}{\textrm}{m}$ thick have been synthesized with DC plasma assisted chemical vapor deposition. The position of a specimen has been controlled by computer-driven stage. With copper vapor laser beam of 7W cutting depth increases rapidly and saturates with increasing scan number and decreasing scan speed. 8 repetitive scans at scan speed 0.5 mm/sec produce the maximum cutting depth without focus shifting Rod-shape copper vapor laser beam can be made and used effectively in planar-ization of rough diamond surface.

• 대한전기학회논문지
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• 제35권9호
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• pp.375-379
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• 1986

The HCP(Hypocycloidal Pinch) device for plasma focus was modified for a pumping source of the dye laser, and the spectral distribution and time behavior of its light pulses were investigated by using a UV spectrometer, 70 MHz CRO and Si-PIN photodiode detector. An array of multiple stages of HCP and narrower electrode gaps were chosen in order to make a more uniform discharge along the HCP axis. The possible spectral range for the pumping of dye laser is 360-620nm, when the HCP is operated at 5-8kv of apllied voltage and 50-150Torr of Ar fill gas pressure. The rise-time and FWHM of light pulses from the HCP are 5us and 30-50us respectively when it is operated under the same conditions as above.

• 대한치과기공학회지
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• 제34권3호
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• pp.221-226
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• 2012

Purpose: This study was performed to compare mechanical properties for sintering methods of porous Ti implants. Methods: The specimens of Ti implant were fabricated by several sintering methods. One of them is spark plasma sintering(SPS). Another is electro discharge singering(EDS) and the other is high vacuum sintering(HVS). Mechanical properties of porous Ti implants were evaluated by universal testing machine(UTM) and their fracture surface was examined under a sanning electron microscope(SEM). Results: The tensile strength was in a range of 71 to 230 MPa, and Young's modulus was in a range of 11 to 21 Gpa. It matched with range of cortical bone. Conclusion: Mechanical properties of porous Ti implants were similar to human bone. It was shown that sintering methods of spherical powders can efficiently produce porous Ti implants with various porosities. Porous metals will be commonly used in orthopedic and dental application despite of initial focus has been on bioceramics.

• 천문학회지
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• 제54권5호
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• pp.157-170
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• 2021

We investigate flow and magnetic structure of a solar prominence with a focus on how the magnetic field originally determined by subsurface dynamics gives rise to the structure. We perform a magnetohydrodynamic simulation that reproduces the self-consistent evolution of a flow and the magnetic field passing freely through the solar surface. By analyzing Lagrangian displacements of magnetized plasma elements, we demonstrate the flow structure that is naturally incorporated to the magnetic structure of the prominence formed via dynamic interaction between the flow and the magnetic field. Our results explain a diverging flow on a U-loop, a counterclockwise downdraft along a rotating field line, acceleration and deceleration of a downflow along an S-loop, and partial emergence of a W-loop, which may play key roles in determining structural properties of the prominence.

• 청정기술
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• 제26권1호
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• pp.72-78
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• 2020

화석연료의 사용과 바이오가스 생산 과정에서 공기오염과 기후변화문제가 발생된다. 기후변화 주요 원인물질인 이산화탄소와 메탄을 양질의 에너지원으로 전환하는데 연구가 지속되고 있다. 본 연구에서는 바이오가스를 양질의 에너지로 전환하고 태양광과 풍력과 같은 연속생산의 문제가 있는 재생에너지와 연계된 태양연료를 생산하기 위해 플라즈마-탄화물 전환장치를 제안하였다. 그리고 이에 대한 가능성을 제시하기 위해 바이오가스 전환에 영향을 미치는 O₂/C비, 전체가스공급량, CO₂/CH₄공급비의 변화에 따른 전환 및 생성가스 특성 파악하였으며 그 결과는 다음과 같다. O₂/C비가 높아질수록 메탄과 이산화탄소의 전환이 증가하였다. 전체가스공급량은 임의 특정 값에서 최대의 전환을 보였다. CO₂/CH₄비 감소할 때 전환율이 증가되었다. 이상의 결과로 볼 때 본 연구에서 새로이 제안된 플라즈마 산화분해-탄화물 가스화 전환에 의한 태양연료 생산의 가능성이 확인되었다. 그리고 O₂/C비가 0.8이고 CO₂/CH₄를 0.67로 하여 전체가스공급량을 40 L min^-1 (VHSV = 1.37)로 공급할 경우 이산화탄소와 메탄 전환이 최대가 되어 생성가스 중 양질의 연료인 수소와 일산화탄소로의 전환이 최대를 보였다.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2005년도 춘계학술대회
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• pp.192-195
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• 2005

The silicon thin film solar cells were fabricated by 13.56 MHz PECVD (Plasma-Enhanced Chemical-Vapor Deposition) and 60 MHz VHF PECVD (Very High-Frequency Plasma-Enhanced Chemical-Vapor Deposition). We focus on textured ZnO:Al films prepared by RF sputtering and post deposition wet chemical etching and studied the surface morphology and optical properties. These films were optimized the light scattering properties of the textured ZnO:Al after wet chemical etching. Finally, the textured ZnO:Al films were successfully applied as substrates for silicon thin films solar cells. The efficiency of tandem solar cells with $0.25 cm^2$ area was $11.8\%$ under $100mW/cm^2$ light intensity. The electrical properties of tandem solar cells were measured with solar simulator (AM 1.5, $100 mW/cm^2)$ and spectral response measurements.

• 한국전기전자재료학회논문지
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• 제27권9호
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• pp.561-565
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• 2014

Thermoelectric materials have been the topic of intensive research due to their unique dual capability of directly converting heat into electricity or electrical power into cooling or heating. Bismuth telluride ($Bi_2Te_3$) is the best-known commercially used thermoelectric material in the bulk form for cooling and power generation applications In this work we focus on the large scale synthesis of nanostructured undoped bulk nanostructured $Bi_2Te_3$ materials by employing a novel bottom-up solution-based chemical approach. Spark plasma sintering has been employed for compaction and sintering of $Bi_2Te_3$ nanopowders, resulting in relative density of $g{\cdot}cm^{-3}$ while preserving the nanostructure. The average grain size of the final compacts was obtained as 200 nm after sintering. An improved NS bulk undoped $Bi_2Te_3$ is achieved with sintered at $400^{\circ}C$ for 4 min holding time.