• Journal of architectural history
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• v.31 no.4
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• pp.57-70
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• 2022

The Joseon royal family considered the act of burying the placenta very important for various reasons. Accordingly, they developed their own ritual culture of burying the placenta based on the geomancy(Pungsu). In 1661, The King Sukjong's placenta chamber was built in Gong-ju, and later stone objects were added in 1683. Since its establishment, the King Sukjong's placenta chamer have been continuously managed by the Joseon royal family, but During the Japanese colonial period, the placenta chamber was partially destroyed, and now only some stone objects remain in the original site. This study aims to estimate the original style and structure of King Sukjong's placenta chamber by focusing on the stone objects which were discovered through recent field surveys. In addition to that, the stylistic review of Joseon Dynasty's royal placenta chamber was conducted to secure a literary data basis and acquired data were comprehensively analyzed. As a result, Some of the original style and structure of King Sukjong's placenta chamber could be confirmed. The results of this study are expected to help restore the authenticity of the royal placenta chamber damaged in japanese colonial period, and are expected to be a good example in the research methodology of historical evidence of other damaged royal placenta chambers.

• Journal of Haehwa Medicine
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• v.16 no.1
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• pp.31-40
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• 2007

Hominis placenta have been studied as herbal acupuncture because of it's limitation of use. The properties of Hominis placenta are warm and supplement of Jeong-Hyeol, Jin-Ki and I thought that Hominis placenta have various effectiveness. So I considered Hominis placenta in Dong-Eui-Bo-Gam which is famous comprehensive korean traditional medical book. Hominis placenta was mentioned parts of Sin, Chung, Hwa, Heo-Ro, Bu-In and most of them are mentioned in Heo-Ro part. As a source book, Eui-Hak-Ib-Mun was used the most. Prescription used in various parts as mental disease, forgetfulness, tuberculosis, fever, various malnutrition disease, sterility, but it's basic principle action is all supplement of Heo-Ro. In management of Hominis placenta, most useing method is heating with steam and most of additional medicinal stuffs had action of supplying Eum, Yang, Ki, Hyeol in composition of prescription.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.1
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• pp.15-25
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• 2019

Objectives: The aim of this study is to review clinical studies of Hominis Placenta Pharmacopuncutre on Obstetrics & Gynecology diseases. Methods: Key words "Jahageo Yakchim", "Hominis Placenta Pharmacopuncture", "Human Placenta Pharmacopuncture", "Hominis Placenta Pharmacoacupuncutre" were searched on 6 database systems (DBpia, KISS, KTKP, NDSL, Pubmed, CENTRAL) on August 31th 2018. Results: 1 case reports and 4 controlled studies were collected in accordance with the selection and exclusion criteria. The study design, study results and method of intervention were analyzed. Conclusions: This review shows the necessity of large-scale well designed clinical studies of Hominis Placenta Pharmacopuncture on Obstetrics & Gynecology diseases to evaluate the efficacy and safety.

• Journal of Pharmacopuncture
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• v.22 no.4
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• pp.279-283
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• 2019

Hominis placenta pharmacopuncture, a treatment that injects Hominis placenta extract into acupoints, has been suggested in the literature and researches that it could be used for cognitive decline. We experienced a case of mild neurocognitive disorder treated with Hominis placenta pharmacopuncture. Hominis placenta pharmacopuncture could be a possible treatment modality producing substantial clinical result in cognitive function which is assessed with Mini-Mental State Examination-Dementia Screening (MMSE-DS), Korean Version of Montreal Cognitive Assessment (MoCA-K), and Korean-Dementia Rating Scale (K-DRS). A 84-year-old man with mild neurocognitive disorder received Hominis placenta pharmacopuncture on GV20, CV12, and bilateral ST36 for a month. The results of neuropsychological examination showed increase in scores after treatment of Hominis placenta pharmacopuncture. Before treatment, they were 15 points for MoCA-K, and 120 points for K-DRS (7.6%), but after treatment, they elevated by 21 points for MoCA-K and 137 points for K-DRS (100%). MMSE-DS score was 28 points, unchanged before and after treatment. It did not cause any side-effect. Hominis placenta pharmacopuncture could be a safe option for treating mild neurocognitive disorder.

• Preventive Nutrition and Food Science
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• v.12 no.2
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• pp.89-94
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• 2007

Nutrients and hormone levels of dried pig placenta were studied. Placentas were freeze-dried (FD), oven-dried at 60 (OD-60), and 90$^{\circ}C$ (OD-90) and then crushed by a blender into small pieces. FD and OD-60 pig placenta had a higher moisture content than did OD-90, with no difference between FD and OD-60. There were no large differences in compositions of crude protein, crude fat, and crude ash of dried placenta among the treatments and the contents of K, Fe, and ${\alpha}$-tocopherol were highest in FD (p<0.05). Glutamine and glycine were the most abundant amino acids in all dried placenta and tyrosine was highly retained in FD placenta, compared with OD (p<0.05). Estradiol was the major sex hormone, followed by progesterone and testosterone in all dried placentas. Antibiotics including amoxicillin, sulfamethazine, tylosin, and chlorotetracyclin were not detected from the pig placentas tested. These results demonstrate that placenta is a good biomaterial with high nutritional quality, and that freeze drying is superior to oven drying for processing pig placenta.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.85-94
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• 2011

Purpose: Hominis placenta have used widely for women's disease like climacteric syndrome, dysmenorrhea, infertility, but we don't have enough evidence with it. This study is to investigate efficacy and safety of Hominis Placenta on women by investigating papers. Methods: We searched for papers which had Hominis placenta, placental extract associated with women's disease in the Pubmed and Korean journals. Results: 20 papers were found. 15 papers were associated with menopausal disorder. Hominis placenta could have the efficacy on osteoporosis and climacteric syndrome induced by menopause. And each 2 papers were relevant to postpartum symptoms and menses. 1 papers was relevant to pregnancy. Most of studies have shown that Hominis placenta is useful for female disorders. Conclusions: Hominis placenta could be a good treatment for female disorder like climacteric syndrome, dysmenorrhea, infertility. But evidence is not enough with Hominis placenta, so more research will be needed.

• Reproductive and Developmental Biology
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• v.31 no.2
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• pp.97-102
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• 2007

The objective of this study was to analyzed pattern of proteins expression abnormally in cloned bovine placenta. TIMP-2 protein whose function is related to extracellular matrix degradation and tissue remodeling processes was one of differentially up-regulated proteins in SCNT placenta. And one of down-regulated protein in SCNT placenta was identified as vimentin protein that is presumed to stabilize the architecture of the cytoplasm. The expression patterns of these proteins were validated by Western blotting. To evaluate how regulatory loci. of TIMP-2 and vimentin genes was programmed reprogramming in cloned placenta. the status of DNA methylation in the promoter region of TIMP-2 and vimentin genes was analyzed by sodium Bisulfite mapping. The DNA methylation results showed that there was not difference in methylation pattern of TIMP-2 and vimentin loci between cloned and normal placenta. Histone H3 acetylation state of the nucleosome was analyzed in the cloned placental and normal placenta by Western blotting. A small portion of the protein lysates were subjected to Western blotting with the antibodies against anti acetyl-Histone H3. Overall histone H3 acetylation state of SCNT placenta was significantly higher than those of normal placenta cells. It is postulated that cloned placenta at the end of gestation seems to be unusual in function and morphology of placenta via improper expression of TIMP-2 and vimentin by abnormal acetylation states of cloned genome.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.2
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• pp.99-107
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• 2006

Objectives : This experimental study was performed to investigate the effects of the Hominis placenta extracts on skin barrier. Methods : Male hairless mice, average weight 20g, were divided into two groups, intact and treatment group(paired, n=15). Intact group was not applied YB-301(an ointment including Hominis placenta). Treatment group was applied YB-301(an ointment including Hominis placenta) two times a day for 8 days. We observed skin melanin, skin erythema, skin pH, skin humidity, transepidermal water loss. Statistical analysis was performed by using paired sample T-test. Statistical significance was achieved if the probability was less than 5%(p<0.05) or 1%(p <0.01) Results : 1. YB-301(an ointment including Hominis placenta) showed statistically significant effect on skin melamin, skin pH, skin humidity(p<0.05). 2. YB-301(an ointment including Hominis placenta) showed statistically significant inhibitory effect on transepidermal water loss(p<0.01). 3. YB-301(an ointment including Hominis placenta) showed statistically no significant effect on skin erythema(p<0.05). conclusions : YB-301(an ointment including Hominis placenta) was effective m skin melanin, skin pH, skin humidity, transepidermal water loss in our study, so we suggest that Hominis placenta can be used as a ointment ingredient for strengthening the function of skin barrier.

• Journal of Acupuncture Research
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• v.17 no.1
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• pp.67-74
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• 2000

Hominis Placenta has been used as a medicinal stuff for a long time in Oriental Medicine. And further, aqua-acupuncture solution of Hominis Placenta has produced in South Korea recently. Bibliographical study was carried on to investigate the nature of Hominis Placenta and possible indications by aqua-acupuncture as well. The nature of Hominis Placenta is warm and its taste sweet-salty. It is non-poisonous. It has correspondence to the meridians of lung, liver and kidney. Hominis Placenta is mainly effective on recuperation of infirmity and the disease related to infirmity. Aqua-acupuncture solution of Hominis Placenta can be applied to the disease as chronic hepatitis, liver cirrhosis, asthma, pulmonary tuberculosis, sterility, insufficient lactation, degenerative change, neurasthenia and cerebrovascular disease.

• Journal of Medicine and Life Science
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• v.19 no.2
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• pp.39-45
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• 2022

This study was undertaken to assess the potential of body mass index (BMI) as a risk factor for massive hemorrhage (MH) after cesarean section (CS) in patients with placenta previa. We retrospectively reviewed the medical records of patients who underwent CS for placenta previa between January 2010 and December 2018. MH was defined as an estimated blood loss ≥2,000 mL during surgery. Clinical characteristics, including BMI, were compared between the groups with and without MH. Subsequently, multivariable logistic regression analysis was conducted to identify the independent risk factors for MH. A total of 189 patients were included in this study. MH was observed in 28 patients (14.8%). According to the multivariable logistic regression analysis results, the risk factors independently associated with MH were BMI at delivery (adjusted odds ratio [aOR], 1.19; 95% confidence interval [CI], 1.04-1.35; P=0.012), placenta accrete (aOR, 24.55; 95% CI, 2.75-219.02; P=0.004), and total previa degree (aOR, 9.86; 95% CI, 2.71-35.96; P=0.001). The study findings showed that maternal obesity, namely a higher BMI at delivery, was an independent risk factor for MH after CS in patients with placenta previa. Close attention should be paid to the potential risk of hemorrhage associated with maternal obesity as well as the well-known risk factors of placenta accreta and total previa degree.