• Journal of the Korean Geosynthetics Society
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• v.13 no.4
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• pp.153-159
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• 2014

During the winter and spring seasons in Korea, structures such as buried water supply pipelines, roads, railways are frequently damaged due to frost heaving and thawing. Until now, the method of substituting the frost susceptible soil with the gravel or rubbles those are non-frost susceptible materials have been employed in Korea to prevent frost heaving. A series of laboratory soil tests and indoor frozen soil engineering experiments, as well as laboratory frost heaving tests were conducted for seeking the means of utilizing recycled PET bottles as substitute material.

• Proceedings of the KIEE Conference
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• 2005.10c
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• pp.276-278
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• 2005

For over 25 years, the stray currents from DC electric railroads have caused serious interference problems with underground metallic infrastructures in Korea. The most serious interference is reported at the pipelines near the depot areas. Our field survey proves that this phenomena is mainly due to the missing of dedicated rectifiers for mainline, depot and/or workshop areas. Because it takes so much time and costs too much to replace the traction power system, we consider a stray current confinement method which collects the stray currents and drains them to the negative terminal of the rectifier. This can be realized by installing a stray current collecting wire along the depot boundary. Moreover, we found the stray current collecting reinforcement bar located beneath the rails of concrete slab tracks. Using this bar, we arc going to draing the stray currents from mainline rails. In this paper we show the result of field survey on railroad facilities and present the stray current confinement method under field test.

• Journal of Soil and Groundwater Environment
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• v.6 no.3
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• pp.43-52
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• 2001

It is important that the gas collected from wells completed in waste landfill should be continuously and stably transported to pre-treatment stage through pipelines. The transport is generally affected by fluid flow characteristics of landfill, gas reserves, leachate moisture holdup in pipeline, structures and dimensions of pipeline network, etc. This paper analyzes the pipeline transport and collection mechanism for gas generated in a durable waste landfill. From the results, the optimal controlled scheme of blower inlet pressure is proposed for the prevention of trapped gas pocket zones.

• Journal of Korean Society of Water and Wastewater
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• v.30 no.6
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• pp.725-736
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• 2016

There is a growing concern on the improvement of water distribution pipeline for multi-regional water supply system in Korea along with its aging infrastructure. Rehabilitation of large diameter pipeline is more efficient in cost and time compared to replacement with trenching. The procedure for rehabilitation are diagnosis, cleaning, spraying coating material, and final inspection. The internal state of pipeline was carefully diagnosed and got C grade, which required rehabilitation. We found that 17,274,787,000 Korean won could be saved after pipe surface coating because of increased C coefficient of Hazen-Williams equation. Optimal coating material was D polyurea. We also found optimal distance between spraying nozzle and pipe wall to be 70 - 80 cm, which were critical factors for coating quality. This study also illustrated the time for spray drying to be more than 30 min. These results could be used in the quality control process during rehabilitation of aged pipelines.

• Journal of Welding and Joining
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• v.23 no.5
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• pp.43-48
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• 2005

Conventional non-destructive techniques for inspection of the weld in pipelines require significant test time and high cost. Ultrasonic guided waves have been widely studied and successfully applied to various non-destructive tests with advantage of the long-range inspection. In this paper, a study on the application of ultrasonic guided waves to the long-range inspection of the pipeline is presented using a long-range guided wave inspection system, Wavemaker SE16, GUL. The characteristics and setup of the long-range guided wave inspection system and experimental results in pipes of with various diameter are introduced. The experimental results in mock-up pipes with cluster type detects show that the minimum detectable wall thickness reduction with this guided wave system is $2\~3\%$ in the pipe cross section area. And the wall thickness reduction of $5\%$ in cross section area can be detected when actual detection level is used. Therefore, the applicability of the guided wave systeme to long-range inspection of wall thickness reduction in pipes is verified.

• Journal of the Korean Society of Mechanical Technology
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• v.13 no.4
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• pp.71-76
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• 2011

Earth to air heat exchangers made by iron, aluminium, copper and poly-ethylene pipe for single greenhouse heating were experimented and blowers. Earth to air heat exchanger was installed by pipelines in earth tube at 70cm depths and air blower was the heating capacity 3kW/h, As the result, Temperature difference due to temperature history of the inlet and outlet air on the various type in earth tube in greenhouse showed that air temperature at the various type in earth tube, comparison tube were make no difference respectively. Under the experimental condition, heat fluxes and heating load were showed 6,800Kcal/h, 19,699kcal/h generally yield of Lactuca Sativa cultured during days of sowing 90day in greenhouse using copper pipe was 170% incleased.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.352-357
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• 2016

광역상수관은 원수 또는 정수를 자체 수자원확보가 어려운 지자체에 적기에 공급해주는 중요한 역할을 하고 있다. 최근 자연재해에 및 관 노후, 공사 중 사고 등의 원인으로 광역상수관이 파손되는 사례가 발생되었다. 이와 같은 광역상수관의 파손은 상수 보급 수혜지역에 대한 단수피해가 발생될 뿐만 아니라 파손지점에서 상수유량의 분출으로 침수피해를 야기 시킬 수 있게 된다. 본 연구에서는 광역상수관 파손에 따른 파손지역 주변부에서 유량 분출에 의한 침수양상 및 분출지점에 위치하고 있는 지하시설물(지하철 정거장)에 대한 침수피해 영향을 검토하였다. 침수양상 분석 방법은 광역상수관 파손시 분출유량 산정, 지형자료 구축, 표면류 흐름 계산, 침수범람도 작성 순으로 검토를 수행하였다. 광역상수관 파손에 따른 분출유량은 상수관 공급량 $770,000m^3/day$를 기준으로 초당 흐르는 유량(2차원 부정류 흐름 해석)으로 환산하여 유입조건으로 선정하고, 파손위치 및 분출유량에 따른 시나리오를 설정하였다. 광역상수관 파손에 따른 침수양상을 살펴본 결과, 파손 지점의 위치의 지형적 여건에 따라 최대 침수심 및 최대 침수 위치가 상이한 결과가 나타나는 것을 확인할 수 있다. 정거장 주변부 최대 침수심은 0.50m로 정거장 노출부 최소 높이 0.65m(노출부 높이 - 지반고)보다 작은 수치이므로 광역상수관 파손에 따른 분출유량의 정거장 내부 유입은 없는 것으로 분석 되었다.

• Biomedical Science Letters
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• v.27 no.3
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• pp.121-133
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• 2021

Antibody-drug conjugates (ADCs) are drawing much interest due to its great potential to be one of the important options in cancer treatments. ADCs are acting like a magic bullet which delivers cytotoxic drugs specifically to cancerous cells throughout the body, thus attacks these cells, while not harming healthy cells. ADCs are complex molecules that are composed of an antibody having targeting capability and linked-payload or cytotoxic drug killing cancerous cells. The key factors of the success in the development of ADC are selection of appropriate antibody, cytotoxic payload and linker for conjugation. Recently there was considerable progress in ADCs development, and a large number of ADCs gained US FDA approval. About 80 new ADCs are under active clinical studies. In this review we present a brief introduction of the US-FDA approved ADCs and global situation in the clinical studies of ADC pipelines. We address an overview on each component of an ADC design such as target antigens, payloads, linkers, conjugation methods, drug antibody ratio. In addition, we discuss on the trend of ADC market where global big pharmas and domestic biopharmaceutical companies are competing to develop safer and more effective ADCs.

• Geomechanics and Engineering
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• v.18 no.5
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• pp.545-554
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• 2019

The customary approach used in the blast vibration analysis is to derive empirical relations between the peak particle velocities of blast-induced waves and the scaled distance, and to develop patterns limiting the amounts of explosives. During the periods when excavations involving blasting were performed at sites far from residential areas and infrastructure works, this method based on empirical correlations could be effective in reducing vibrations. However, blasting procedures applied by the fast-moving mining and construction industries today can be very close to, in particular cities, residential areas, pipelines, geothermal sites, etc., and this reveals the need to minimize blast vibrations not only by limiting the use of explosives, but also employing new scientific and technological methods. The conventional methodology in minimizing blast vibrations involves the steps of i) measuring by seismograph peak particle velocity induced by blasting, ii) defining ground transmission constants between the blasting area and the target station, iii) finding out the empirical relation involving the propagation of seismic waves, and iv) employing this relation to identify highest amount of explosive that may safely be fired at a time for blasting. This paper addresses practical difficulties during the implementation of this conventional method, particularly the defects and errors in data evaluation and analysis; illustrates the disadvantages of the method; emphasizes essential considerations in case the method is implemented; and finally discusses methods that would fit better to the conditions and demands of the present time compared to the conventional method that intrinsically hosts the abovementioned disadvantages.

• Genomics & Informatics
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• v.16 no.4
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• pp.22.1-22.5
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• 2018

In 1966, the International Classification of Viruses (ICNV) was established to standardize the naming of viruses. In 1975, the organization was renamed "International Committee on Taxonomy of Viruses (ICTV)," by which it is still known today. The primary virus classification provided by ICTV in 1971 was for viruses infecting vertebrates, which includes 19 genera, 2 families, and 24 unclassified groups. Presently, the 10th virus taxonomy has been published. However, the early classification of viruses was based on clinical results "in vivo" and "in vitro," as well as on the shape of the Phenotype virus. Due to the development of next-generation sequencing and the accompanying bioinformatics analysis pipelines, a reconstruction of the classification system has been proposed. At a meeting held in Boston, USA between June 9-11, 2016, there was even an in-depth discussion regarding the classification of viruses using metagenomic data. One suggested activity that arose from the meeting was that viral taxonomy should be reconstructed, based on genotype and bioinformatics analysis "in silico." This article describes our efforts to achieve this goal by construction of a web-based system and the extension of an associated database, based on ICTV taxonomy. This virus taxonomy web system was designed specifically to extend the virus taxonomy up to strain and isolation, which was then connected with the NCBI database to facilitate searches for specific viral genes; there are also links to journals provided by the EMBL RESTful API that improves accessibility for academic groups.