• Molecules and Cells
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• v.26 no.4
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• pp.396-403
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• 2008

The first ORF of the ARV S1133 S1 segment encodes the nonstructural protein p10, which is responsible for the induction of cell syncytium formation. However, p10-dependent signaling during syncytium formation is fully unknown. Here, we show that dominant negative RhoA, Rho inhibitor C3 exoenzyme, ROCK/Rho-kinase inhibitor Y-27632 and Rac1 inhibitor NSC23766 inhibit p10-mediated cell fusion. p10 over-expression is concomitant with activation and membrane translocation of RhoA and Rac1, but not cdc42. RhoA and Rac1 downstream events, including JNK phosphorylation and transcription factor AP-1 and $NF-{\kappa}B$ activation, as well as MLC expression and phosphorylation are simultaneously activated by p10. p10 point mutant T13M possessed 20% fusion-inducing ability and four p10 fusion-deficient mutants V15M, V19M, C21S and L32A reduced or lost their ability to activate RhoA and Rac1 signaling. We conclude that p10-mediated syncytium formation proceeds by utilizing RhoA and Rac1-dependent signaling.

• Proceedings of the Korean Society of Grassland Science Conference
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• 2005.06a
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• pp.206-207
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• 2005

• Journal of Fashion Business
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• v.12 no.1
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• pp.76-92
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• 2008

The purpose of this study was to analyze the general wearing attitude & brand Image Perception for Golf Wear in wearer's mind, and to investigate the brand preference on the image characteristics of golf wear, and to find out the wearer's purchasing point for golf wear, for developing the possibility and strategy of the golf wear market for the apparel marketers and manufacturers. For this study, the data obtained from 210 respondents were analyzed by the descriptive statistics, Pearson's simple correlation, Crossing Analysis, parato graph. The results from the study were as follow : The respondents who were specially wearing for golf game were 23.3%(49 persons) among the 210 respondents. The 210 respondents evaluated highly the features of golf wear, such as design(51%), quality(44.3%), materials(36.2%), color(35.2%), size(21.0%), as the purchasing point for golf shirts, otherwise, the 210 respondents evaluated lowly the social aspects of golf wear, such as, fashion conformity, brand loyalty and promotion. And the most important material features for the golf wear was the elasticity, speed dryness by the 210 respondents The most frequent brand by 207 respondents described in the free style was Daks(11.1%) and Ping(11.1%). The 205 respondents described in the free style evaluated Daks(14.6%) as the most preference brand. The reason for the most preference brand was based with the comfort and pleasure of design, quality, color, size, materials.

• Journal of Fashion Business
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• v.6 no.4
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• pp.113-124
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• 2002

The purpose on this study identified the purchasing conditions of Sports wear of the Chinese men residing in Beijing, Shanghai, Dalian, Tianjin, Harbin and Guangzhou, so that it helped sports wear manufacturers and retailers offer the basic data. For the study, a questionnaire used as a method of measurement, the 863 Chinese men were selected as a sample, SAS(Statistical Analysis System) program was used to analyze the data. The results from the study were as follows: 1. According to the investigation, the most preferred sports of Chinese men is soccer, as a whole. Swimming, basketball and ping-pong keep rank the next to soccer. 2. Accordingly age, area, profession and income, Chinese men maintained sports suit in order of training suit, swimming suit, soccer suit, tennis suit. It is found that holding amount of high-quality sports wears as ski, golf is on a low level. 3. It is appeared that Chinese men purchased in good order as follow brand: No-bran, Nike, Lening, Adidas. And except Nike, they purchased more Lening brand than foreign sports brand. 4. As the result of researching on the item of sports wear, it is found that they purchased various kind items in a higher rank 5 brands. 5. Sports wear's color that Chinese men purchased is blue, white, black, red. 6. The purchasing price that Chinese men favored is 200$\sim$599RMB. Thus, they expend average per head for sports suit buying, 486.0RMB. 7. Chinese men purchased very often at specialty store. And, coefficient of utilization at the usual market is on a low level. 8. In purchasing satisfaction, 80 % Chinese men were satisfied with goods(sports wear) that purchased in a higher rank 5 brands. So, average satisfaction degree showed over 3.8 as a high rate. 9. According to the result of satisfaction on Chinese men, 70% Chinese men showed satisfaction. Therefore, the average of satisfaction degree appeared 3.81 as a high rate.

• Journal of Information Processing Systems
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• v.6 no.1
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• pp.1-20
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• 2010

Due to the convergence of voice, data, and video, today's telecom operators are facing the complexity of service and network management to offer differentiated value-added services that meet customer expectations. Without the operations support of well-developed Business Support System/Operations Support System (BSS/OSS), it is difficult to timely and effectively provide competitive services upon customer request. In this paper, a suite of NGOSS-based Telecom OSS (TOSS) is developed for the support of fulfillment and assurance operations of telecom services and IT services. Four OSS groups, TOSS-P (intelligent service provisioning), TOSS-N (integrated large-scale network management), TOSS-T (trouble handling and resolution), and TOSS-Q (end-to-end service quality management), are organized and integrated following the standard telecom operation processes (i.e., eTOM). We use IPTV and IP-VPN operation scenarios to show how these OSS groups co-work to support daily business operations with the benefits of cost reduction and revenue acceleration.

• Geomechanics and Engineering
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• v.13 no.6
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• pp.1011-1025
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• 2017

The geological conditions surrounding the Jijiapo Tunnel of the Three Gorges Fanba Highway project in Hubei Province are very complex. In this paper, a 3-D physical model was carried out to study the evolution process of filling-type fracture water inrush and mud gush based on the conditions of the section located between 16.040 km and 16.042 km of the Jijiapo Tunnel. The 3-D physical model was conducted to clarify the effect of the self-weight of the groundwater level and tunnel excavation during water inrush and mud gush. The results of the displacement, stress and seepage pressure of fracture and surrounding rock in the physical model were analyzed. In the physical model the results of the model test show that the rock displacement suddenly jumped after sustainable growth, rock stress and rock seepage suddenly decreased after continuous growth before water inrushing. Once water inrush occured, internal displacement of filler increased successively from bottom up, stress and seepage pressure of filler droped successively from bottom up, which presented as water inrush and mud gush of filling-type fracture was a evolving process from bottom up. The numerical study was compared with the model test to demonstrate the effectiveness and accuracy of the results of the model test.

• Korean Journal of Remote Sensing
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• v.26 no.2
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• pp.175-188
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• 2010

A new correction method is required for the Geostationary Ocean Color Imager (GOCI), which is the world's first ocean color observing sensor in geostationary orbit. In this paper we introduce a new method of atmospheric and the Bidirectional Reflectance Distribution Function(BRDF) correction for GOCI. The Spectral Shape Matching Method(SSMM) and the Sun Glint Correction Algorithm(SGCA) were developed for atmospheric correction, and BRDF correction was improved using Inherent Optical Property(IOP) data. Each method was applied to the Sea-Viewing Wide Field-of-view Sensor(SeaWiFS) images obtained in the Korean sea area. More accurate estimates of chlorophyll concentrations could be possible in the turbid coastal waters as well as areas severely affected by aerosols.

• Geomechanics and Engineering
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• v.19 no.2
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• pp.115-126
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• 2019

The long-term settlement characteristics for the cast-in-place bored pile in the deep-thick soft soil are investigated by post-grouting field tests. Six cast-in-place bored engineering piles and three cast-in-place bored test piles are installed to study the long-term settlement characteristics. Three post-grouting methods (i.e., post-tip-grouting, post-side-grouting, and tip and side post-grouting) are designed and carried out by field tests. Results of the local test show that decreased settlements for the post-side-grouted pile, the post-tip-grouted pile and the tip and side post-grouted pile are 22.2%~25.8%, 30.10%~35.98% and 32.40%~35.50%, respectively, compared with non-grouted piles. The side friction resistance for non-grouted piles, post-side-grouted pile, post-tip-grouted pile and the tip and side post-grouted pile undertakes 89.6~91.3%, 94.6%, 92.4%~93.0%, 95.7% of the total loading, respectively. At last, the parameters back analysis method and numerical calculation are adopted to predict the long-term settlement characteristics of the cast-in-place bored pile in the deep-thick soft soil. Determined Bulk modulus (K) and a creep parameter (Ks) are used for the back analysis of the long-term settlement of the post-grouted pile. The settlement difference between the back analysis and the measurement data is about 1.11%-7.41%. Long-term settlement of the post-grouted piles are predicted by the back analysis method, and the predicted results show that the settlement of the post-grouted pile are less than 6 mm and will be stable in 30 days.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.6
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• pp.483-491
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• 2019

Cordycepin exerts neuroprotective effects against excitotoxic neuronal death. However, its direct electrophysiological evidence in Alzheimer's disease (AD) remains unclear. This study aimed to explore the electrophysiological mechanisms underlying the protective effect of cordycepin against the excitotoxic neuronal insult in AD using whole-cell patch clamp techniques. ${\beta}$-Amyloid ($A{\beta}$) and ibotenic acid (IBO)-induced injury model in cultured hippocampal neurons was used for the purpose. The results revealed that cordycepin significantly delayed $A{\beta}$ + IBO-induced excessive neuronal membrane depolarization. It increased the onset time/latency, extended the duration, and reduced the slope in both slow and rapid depolarization. Additionally, cordycepin reversed the neuronal hyperactivity in $A{\beta}$ + IBO-induced evoked action potential (AP) firing, including increase in repetitive firing frequency, shortening of evoked AP latency, decrease in the amplitude of fast afterhyperpolarization, and increase in membrane depolarization. Further, the suppressive effect of cordycepin against $A{\beta}$ + IBO-induced excessive neuronal membrane depolarization and neuronal hyperactivity was blocked by DPCPX (8-cyclopentyl-1,3-dipropylxanthine, an adenosine $A_1$ receptor-specific blocker). Collectively, these results revealed the suppressive effect of cordycepin against the $A{\beta}$ + IBO-induced excitotoxic neuronal insult by attenuating excessive neuronal activity and membrane depolarization, and the mechanism through the activation of $A_1R$ is strongly recommended, thus highlighting the therapeutic potential of cordycepin in AD.

• Nuclear Engineering and Technology
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• v.53 no.4
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• pp.1236-1249
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• 2021

Although there are still controversial opinions and uncertainty on application of SiC_f/SiC composite cladding as next-generation cladding material for its great oxidation resistance in high temperature steam environment and other outstanding advantages, it cannot deny that SiC_f/SiC cladding is a potential accident tolerant fuel (ATF) cladding with high research priority and still in the engineering design stage for now. However, considering its disadvantages, such as low irradiated thermal conductivity, ductility that barely not exist, further evaluations of its in-pile behaviors are still necessary. Based on the self-developed code we recently updated, relevant thermohydraulic and mechanical models in FROBA-ATF were applied to simulate the cladding behaviors under normal and accident conditions in this paper. Even through steady-state performance analysis revealed that this kind of cladding material could greatly reduce the oxidation thickness, the thermal performance of UO₂-SiC was poor due to its low inpile thermal conductivity and creep rate. Besides, the risk of failure exists when reactor power decreased. With geometry optimization and dopant addition in pellets, the steady-state performance of UO₂-SiC was enhanced and the failure risk was reduced. The thermal and mechanical performance of the improved UO₂-SiC was further evaluated under Loss of coolant accident (LOCA) and Reactivity Initiated Accident (RIA) conditions. Transient results showed that the optimized ATF had better thermal performance, lower cladding hoop stress, and could provide more coping time under accident conditions.