• 대한토목학회논문집
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• 제41권1호
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• pp.57-64
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• 2021

도시부도로에서 변속차로는 도로가 연결되는 지점에 설치되어 상대속도를 낮추도록 함으로써 교통소통을 원활하게 하고 있다. 그러나 도심내 안전 속도 "5030"시행에 따른 제한속도 30 km/h의 경우 기준이 모호하여 변속차로 설치에 대한 지적이 나오고 있다. 본 연구는 변속차로에 대한 이론적 고찰 후 안전속도 "5030" 정책 시행 예정 구간을 중심으로 변속차로 통행패턴을 사례조사를 실시하였다. 현장조사 후 도로조건 및 교통 조건 등에 따라 주도로의 통행 속도별 통행 패턴을 분석한 결과 안전속도 "5030"시행에 따른 변속차로의 실효성을 분석하였다. 본 연구수행을 통해 제시된 속도별 변속차로 설치기준은, 통행속도 30 km/h 구간인 경우는 변속차로를 미설치 하도록 하고, 50 km/h인 경우는 반드시 설치토록 하는 기준을 제시하였다. 향후 도시지역에서 다른 시설의 연결에 대한 공학적 기준을 정립할 때 참고할 수 있을 것으로 판단되며, 변속차로 설치 및 회전반경 확대를 통한 속도별 원활한 교통소통 및 안전성을 확보하고 개인의 사유재산권 행사에 대한 불필요한 제약을 최소화하는데 기여할 수 있을 것으로 기대된다.

• 한방안이비인후피부과학회지
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• 제26권2호
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• pp.10-18
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• 2013

Objectives : We performed a pilot study to investigate inter- and intra-rater reliability of pattern identification using nasal endoscopy for allergic rhinitis(AR). Methods : Eight experts of ophthalmology, otolaryngology and dermatology of Korean medicine evaluated 20 nasal endoscopy photograph cases of AR patients with pattern identification index using nasal endoscopy for AR including the nasal membrane color(pale / hyperemia), nasal membrane humidity(dryness / dampness), rhinorrhea(watery / yellow), and membrane edema (atrophic / edematous) on nasal endoscopy. Results : Intra-rater agreement(%) and Kappa coefficient was generally from 'moderate' to 'good'(% agreement: 73.13-90% / Kappa coefficient: 0.547-0.748). Inter-rater agreement(%) and Kappa coefficient was also from 'moderate' to 'good' (% agreement: 65-85% / Kappa: 0.475-0.778) except 'humidity(dryness / dampness)' item (% agreement: 55.98% / Kappa: 0.340). In findings of subgroup analysis according to affiliation of raters, Inter-rater agreement(%) and Kappa coefficient of raters in same affiliation was higher than inter-rater agreement(%) and Kappa coefficient of raters in different affiliation except 'dryness / dampness' item. Conclusions : It is necessary to improve objectivity and reproducibility of pattern identification using nasal endoscopy for allergic rhinitis(AR) through the development of detail-oriented criteria and enhanced training of clinicians with development of standard operating procedures(SOPs).

• 지질공학
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• 제12권1호
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• pp.75-88
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• 2002

오염된 연약지반에 편재하중이 작용하게 되면 지반 중에 침하, 측방변위, 융기 및 전단파괴 등의 큰 소성 전단변형이 발생하게 되고, 때로는 지반과 구조물에 막대한 손상을 초래하게 된다. 따라서 본 연구는 오염된 연약지반의 식내모형실험을 실시하였으며 측방유동압의 결정방법을 기존의 이론식과 비교하여 분석하였다. 모형실험은 먼저 모형재하장치를 제작하고 토조 안에 오염된 지반시료를 채워 비배수상태에서 하중을 인정한 시간 간격으로 재하하여 변형상태를 관측하였다. 그 결과 편재 하중을 받는 오염된 연약지반에서의 측방유동압은 P=K$_{0}$YH식에 의해서 산정함이 비교적 적절하며, 측방유동압의 최대값은 토층두께(H)의 0.3H 부근에서 발생하였다. 또한 종합형과 Poulos의 분포형태 및 오염되지 않는 연약점토(CL, CH) 지반보다 지표면측으로 상승하여 발생하였다.

• 대한한방내과학회지
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• 제35권2호
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• pp.157-174
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• 2014

Objectives : The aims of this study were to evaluate the diagnostic values of tongue coating thickness and sterno-costal angle as the quantitative diagnostic indicators in functional dyspepsia. Methods : We surveyed 60 functional dyspepsia patients recruited by the clinical trial, 'Clinical Trial for Evaluation on Availability of tongue diagnosis system (CTS-1000) : a Pilot study'. The patients were classified into three groups according to Rome III criteria for functional dyspepsia, and categorized into five groups according to Instrument of pattern identification for functional dyspepsia. Nepean dyspepsia index-Korean version (NDI-K) score, tongue coating thickness (percentage of tongue coating by tongue diagnosis system (CTS-1000), and weight of tongue coating by microbalance), sterno-costal angle, duration of illness and body mass index (BMI) were investigated. Results : Among the 5 types by instrument of pattern identification for functional dyspepsia, a significant difference of percentage of tongue coating was found. Percentage of tongue coating and weight of tongue coating showed significant correlation with total NDI-K score. Sterno-costal angle showed strong positive correlation with BMI and also showed significant difference between the non-overweight (BMI<23, n=32) and overweight ($BMI{\geq}23$, n=28) groups. Conclusions : Tongue coating thickness showed its potential as a new quantitative diagnostic indicator of functional dyspepsia. Further studies on the sterno-costal angle are anticipated to evaluate its potential as a new quantitative diagnostic indicator.

• Ocean and Polar Research
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• 제32권1호
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• pp.15-22
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• 2010

Calcium carbonate ($CaCO_3$) content was measured from 3 box core (BC060301, BC060303, BC070301) sediments, in addition to pilot core (PC313) sediments, from deep waters within the Western Pacific Ocean. At the two collection sites (BC060301, PC313) located close to the equator, downcore variation exhibited low $CaCO_3$ content during the interglacial period and high $CaCO_3$ content during the glacial period. Variation of coarse fraction (>$63\;{\mu}m$) content also followed changes in $CaCO_3$ content, indicating that dissolution effect of bottom water decreased during the glacial period. Such variation pattern is typical of the Pacific Ocean. However, downcore variation at the two collection sites (BC060303, BC070301) in the Philippine Sea contrasted the trend of the previous two cores (i.e., high $CaCO_3$ content during the interglacial period and low during the glacial period). This pattern is typical of the Atlantic Ocean. Such results may be attributed to the increasing dilution effect, initiated possibly by the increased transportation of terrigenous materials from nearby continent and archipelago during the glacial period when sea level was low. Alternatively, it is possible that the non-carbonate biogenic particles may have been responsible for dilution. Because of these uncertainties, the record of $CaCO_3$ variation in the deep Western Pacific Ocean is not regionally consistent.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6069-6075
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• 2013

Background: At present, the diagnosis of colorectal cancer (CRC) requires a colorectal biopsy which is an invasive procedure. We undertook this pilot study to develop an alternative method and potential new biomarkers for diagnosis, and validated a set of well-integrated tools called ClinProt to investigate the serum peptidome in CRC patients. Methods: Fasting blood samples from 67 patients diagnosed with CRC by histological diagnosis, 55 patients diagnosed with colorectal adenoma by biopsy, and 65 healthy volunteers were collected. Division was into a model construction group and an external validation group randomly. The present work focused on serum proteomic analysis of model construction group by ClinProt Kit combined with mass spectrometry. This approach allowed construction of a peptide pattern able to differentiate the studied populations. An external validation group was used to verify the diagnostic capability of the peptidome pattern blindly. An immunoassay method was used to determine serum CEA of CRC and controls. Results: The results showed 59 differential peptide peaks in CRC, colorectal adenoma and health volunteers. A genetic algorithm was used to set up the classification models. Four of the identified peaks at m/z 797, 810, 4078 and 5343 were used to construct peptidome patterns, achieving an accuracy of 100% (> CEA, P<0.05). Furthermore, the peptidome patterns could differentiate the validation group with high accuracy close to 100%. Conclusions: Our results showed that proteomic analysis of serum with MALDI-TOF MS is a fast and reproducible approach, which may provide a novel approach to screening for CRC.

• The Journal of Advanced Prosthodontics
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• 제11권6호
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• pp.331-340
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• 2019

PURPOSE. The purpose of this study is to assess the accuracy of three intraoral scanners along the complete dental arch and evaluate the feasibility of the assessment methodology for further in vivo analysis. MATERIALS AND METHODS. A specific measurement pattern was fabricated and measured using a coordinate measuring machine for the assessment of control distances and angles. Afterwards, the pattern was placed and fixed in replica of an upper jaw for their subsequent scans (10 times) using 3 intraoral scanners, namely iTero Element1, Trios 3, and True Definition. 4 reference distances and 5 angles were measured and compared with the controls. Trueness and precision were assessed for each IOS: trueness, as the deviation of the measures from the control ones, while precision, as the dispersion of measurements in each reference parameter. These measurements were carried out using software for analyzing 3-dimensional data. Data analysis software was used for statistical and measurements analysis (α=.05). RESULTS. Significant differences (P<.05) were found depending on the intraoral scanner used. Best trueness values were achieved with iTero Element1 (mean from 10 ± 7 ㎛ to 91 ± 63 ㎛) while the worst values were obtained with Trios3 (mean from 42 ± 23 ㎛ to 174 ± 77 ㎛). Trueness analysis in angle measurements, as well as precision analysis, did not show conclusive results. CONCLUSION. iTero Element1 was more accurate than the current versions of Trios3 and True Definition. Importantly, the proposed methodology is considered reliable for analyzing accuracy in any dental arch length and valid for assessing both trueness and precision in an in vivo study.

• Journal of Periodontal and Implant Science
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• 제40권2호
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• pp.49-55
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• 2010

Purpose: The purpose of this study was to preliminarily evaluate the influence of diabetes mellitus (DM) on periodontal tissue without establishment of periodontitis. Methods: Seven-week-old db/db mice were used for the diabetic experimental group and systematically healthy mice of the same age were used as controls. After 1 week of acclimatization, the animals were sacrificed for hard and soft tissue evaluation. The pattern of bone destruction was evaluated by stereomicroscope evaluation with alizarin red staining and radiographic evaluation by microscopic computerized tomography images. Histological evaluation was performed with hematoxylin and eosin stain for evaluation of soft tissue changes. Results: In both stereomicroscope evaluation and radiograph image analysis, aggressive form of bone destruction was observed in diabetic animals when compared to the systematically healthy controls. In histological evaluation, apical migration of junctional epithelium with slight inflammatory cell infiltration was observed with disarrangement of connective tissue fibers. Conclusions: Within the limits of this study, diabetic animals presented distortion in periodontal attachment and an aggressive bone loss pattern when compared to the healthy controls, suggesting that DM has an independent effect on periodontal tissue destruction irrespective of the presence or absence of periodontal disease.

• 농업생명과학연구
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• 제52권6호
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• pp.111-125
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• 2018

본 연구에서는 변량방제기술을 적용한 농용 회전익기를 이용하여 살포한 입자의 구간비행 상태에서의 거리별 살포 패턴을 측정함으로써 무인 항공방제의 농약 부착률과 입자경의 분포 균일도를 평가하였다. 비행을 등속으로 유지하는 안내비행과 자동비행 모드에서 유효살포폭 3.6m로 인접비행 구간과 살포폭이 일부 중첩된 피복률에 대한 가로방향 분포의 변이계수는 30% 정도를 보였고, 비행방향 진로위치에 대한 피복률의 변이계수는 10% 미만으로 매우 균등한 것으로 평가되었다. 따라서 살포작업시 기체의 지면속도(ground speed)의 변이를 보상하는 변량살포기술은 균일도 측면에서 우수한 것으로 판명되었으며, 또한 입자경의 분포에 있어서 체적중위직경(VMD)과 개체중위직경(NMD) 모두 항공방제에 적절한 크기와 균일한 분포를 보였다. 따라서 농용 회전익기를 이용하여 소필지의 항공방제작업을 무인화 하는데 있어, 변량방제장치를 적용함으로써 소규모 필지의 균일 정밀방제를 도모하고자 하였다.

• 대한토목학회논문집
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• 제30권3D호
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• pp.263-270
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• 2010

본 연구는 경제분석기법에서 편익항목의 통행시간절감편익의 개선안을 살펴보았다. 기존의 경제성분석 시 통행시간절감편익의 계산방법은 피크시간대의 O/D를 이용하여365를 곱하여 산정하고 있다. 이 계산방법의 문제점은 요일에 대한 교통량변화, 달에 대한 교통량변화를 고려하지 못하는 것이다. 이러한 분석점을 개선하기 위하여, 군집분석과 t-검증을 통하여 달별, 요일별 비슷한 교통량 패턴이 가지는 것끼리 묶었다. 이러한 결과값은 요일별과 월별로 교통량의 차이가 발생하는 것으로 나타났다. 본 연구에서는 이러한 요일별, 월별 가중치를 적용하여 pilot 예제를 통해 통행시간절감분을 계산하였더니 기존의 방법에 비해 다소 적게 도출되는 것을 알 수 있었다. 본 연구는 교통량의 변화패턴을 고려한 가중치 연구에 의의를 둘 수 있다.