• 제목/요약/키워드: Pigmented villonodular synovitis

검색결과 36건 처리시간 0.021초

근골격계 종양에서 사이토카인 발현의 분석 (The Analysis of the Cytokine Expression in Musculoskeletal Tumors)

  • 이준한;곽은석;손욱진;김희선;신덕섭
    • Journal of Yeungnam Medical Science
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    • 제20권2호
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    • pp.187-196
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    • 2003
  • The cytokines are the hormone-like proteins, which are produced in the mononuclear cells. They have many roles, such as immune mediators, cell differentiations, angiogenesis. The chemokines have chemotactic effects which control the host immune response. There were few reports about the cytokines associated with musculoskeletal tumors. From late 1980s, the cytokine studies of bone tumors such as osteosarcoma were started, but most studies for benign and malignant musculoskeletal tumors were left to be explored. To evaluate the characteristics of the cytokines in variable musculoskeletal tumors, tissues were obtained from the seven patients who visited the Yeungnam University hospital from February to July 2000. They were lipoma (1 case), parosteal osteoma (1 case), enchondroma (2 cases), pigmented villonodular synovitis (1 case), ganglion (1 case), and metastaic squamous cell carcinoma (1 case). The gene experession of the cytokines were analyzed by RNase protection assay (RPA) and reverse transcription-polymerase chain reaction (RT-PCR). The lipoma and parosteal osteoma expressed MIP-$1{\beta}$, and IP-10 genes. The two enchondromas showed different results, one expressed all of MIP-$1{\alpha}$, MIP-$1{\beta}$ and IP-10 genes but the other expressed none of above. The pigmented villonodular synovitis strongly expressed MIP-$1{\alpha}$ and IP-10 when compared with the other cases. The ganglion did not express all of the chemokines mentioned above. And the metastatic squamous cell carcinoma expressed all of the chemokines and especially IP-10 was highly expressed. Even though this study has only a few cases, these results provide a basis for the cytokine mediating network study in musculoskeletal tumors.

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측두하악관절에 발생한 색소성 융모결절성 활막염(Pigmented Villonodular Synovitis)의 영상진단 (Diagnostic Imaging of Pigmented Villonodular Synovitis of the Temporomandibular Joint.)

  • 송만용;이경희;이상철;이삼선;최순철;박태원;유동수
    • 치과방사선
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    • 제28권2호
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    • pp.505-519
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    • 1998
  • The occurrence of PVNS in the TMJ is very rare. We report a case of PVNS which was misdiagnosed as a parotid tumor at first. CT and conventional radiograph revealed a well defined mass demonstrating higher attenuation than adjacent soft tissue. Erosion and expansion of the cortical plate of the mandibular condyle and sclerotic change beneath the margin of the lesion were also shown. MRI demonstrated well defined mass of very low signal intensity on both Tl and T2-weighted images due to ferromagnetic effect of the high concentrated hemosiderin and clearly delineated the extent of the lesion. Histopathologic findings and characteristic appearance of the various imaging methods were described and the usefulness of these images for diagnosis and pretreatment evaluation of PVNS were also discussed.

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완전 격막형 슬개상 추벽에 의해 합병된 슬개상 점액낭 내 외상성 출혈 -1예 보고- (Traumatic Hemorrhage in Suprapatellar Bursa Complicated by Suprapatellar Plica with Complete Septum -A Case Report-)

  • 고해석;인용
    • 대한관절경학회지
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    • 제12권1호
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    • pp.63-65
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    • 2008
  • 37세 남자의 슬개상 점액낭내 외상성 출혈을 치험하여 보고하고자 한다. 둔탁한 외상 후 슬개상 부종과 통증이 지속되었고, 방사선 사진에서 비정상 소견은 보이지 않았지만, 자기 공명 영상의 시상면 사진상 액체액체층이 있는 고립된 슬개상 낭종이 관찰되었다. 관절경적 검사에서 완전한 격막의 슬개상 추벽이 있었고 슬관절내에 활액막염의 소견은 없었으며 슬개상 추벽을 절제하자 점액낭에 고여있던 혈액이 새어 나왔다. 슬개상 점액낭 내에 색소성 융모 결절성 활액막염이나 다른 종양을 의심할 만한 병변은 없었다. 수술 후 증상은 소실되었고 추시 6개월째 재발은 없었다.

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A case report of an unusual temporomandibular joint mass: Nodular fasciitis

  • Han-Sol Lee;Kyu-Young Oh;Ju-Hee Kang;Jo-Eun Kim;Kyung-Hoe Huh;Won-Jin Yi;Min-Suk Heo;Sam-Sun Lee
    • Imaging Science in Dentistry
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    • 제53권1호
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    • pp.83-89
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    • 2023
  • Nodular fasciitis (NF) is a benign myofibroblastic proliferation that grows very rapidly, mimicking a sarcoma on imaging. It is treated by local excision, and recurrence has been reported in only a few cases, even when excised incompletely. The most prevalent diagnoses of temporomandibular joint(TMJ) masses include synovial chondromatosis, pigmented villonodular synovitis, and sarcomas. Cases of NF in the TMJ are extremely rare, and only 3 cases have been reported to date. Due to its destructive features and rarity, NF has often been misdiagnosed as a more aggressive lesion, which could expose patients to unnecessary and invasive treatment approaches beyond repair. This report presents a case of NF in the TMJ, focusing on various imaging features, along with a literature review aiming to determine the hallmark features of NF in the TMJ and highlight the diagnostic challenges.

T2 강조 MR 영상에서 저신호강도를 보이는 윤활막 질환 (Synovial Lesions with Low Signal Intensities on T2-Weighted MR Image)

  • 추혜정;이선주;조길호;서경진;이성문;이영환;이인숙;이경규;김보미
    • Investigative Magnetic Resonance Imaging
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    • 제15권1호
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    • pp.1-10
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    • 2011
  • 색소성 융모결절성 윤활막염, 윤활막 연골종증, 장기간의 류마티스 관절염, 혈우병성 관절병증, 만성 결절성 통풍, 아밀로이드성 관절병증, 결핵성 관절염, 그리고 혈관종 등은 T2 강조 MR 영상에서 저신호강도를 보인다. 혈철소, 요산, 아밀로이드의 윤활막 침착, 증식된 윤활막의 섬유화, 치즈괴사 등이 T2 저신호강도의 병리적 원인으로 알려져 있다. T2 강조영상에서 저신호강도를 보이는 윤활막 질환의 빈도는 낮으므로 이에 대한 숙지는 질환의 정확한 진단에 도움을 줄 것이다.

양측 손목의 힘줄에 생긴 미만형의 건활막거대세포종 (Diffuse-Type Tenosynovial Giant Cell Tumor of the Tendon Sheath in Both Wrists)

  • 허선아;박선영;서진원;고성혜;이인재
    • 대한영상의학회지
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    • 제82권1호
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    • pp.250-254
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    • 2021
  • 건활막거대세포종은 이전에 색소성융모결절성 활막염으로 불리던 질환으로, 활막, 점액낭, 힘줄 등에 생기는 드문 양성 종양이다. 미만형의 건활막거대세포종은 국소형에 비해 드물고 그중에서도 관절 외에 발생하는 것은 더 드물다. 또한 대부분은 하나의 관절을 침범하기 때문에 양측을 대칭적으로 침범한 것도 매우 드물다. 이에 저자들은 64세 여자 환자에서 양측 손목의 신전건과 굴곡건을 모두 침범한 관절 외 미만형의 건활막거대세포종의 증례에 대해 초음파와 자기공명영상검사 소견을 중심으로 보고하고자 한다.